KEGG   ORTHOLOGY: K05719Help
Entry
K05719                      KO                                     

Name
ITGB1, CD29
Definition
integrin beta 1
Pathway
Rap1 signaling pathway
Phagosome
PI3K-Akt signaling pathway
Axon guidance
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Tight junction
Platelet activation
Leukocyte transendothelial migration
Regulation of actin cytoskeleton
Bacterial invasion of epithelial cells
Pathogenic Escherichia coli infection
Shigellosis
Pertussis
Leishmaniasis
Toxoplasmosis
Human papillomavirus infection
Pathways in cancer
Proteoglycans in cancer
Small cell lung cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K05719  ITGB1, CD29; integrin beta 1
   04151 PI3K-Akt signaling pathway
    K05719  ITGB1, CD29; integrin beta 1
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K05719  ITGB1, CD29; integrin beta 1
   04514 Cell adhesion molecules (CAMs)
    K05719  ITGB1, CD29; integrin beta 1
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K05719  ITGB1, CD29; integrin beta 1
  Cellular community - eukaryotes
   04510 Focal adhesion
    K05719  ITGB1, CD29; integrin beta 1
   04530 Tight junction
    K05719  ITGB1, CD29; integrin beta 1
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05719  ITGB1, CD29; integrin beta 1
 Organismal Systems
  Immune system
   04611 Platelet activation
    K05719  ITGB1, CD29; integrin beta 1
   04670 Leukocyte transendothelial migration
    K05719  ITGB1, CD29; integrin beta 1
  Development
   04360 Axon guidance
    K05719  ITGB1, CD29; integrin beta 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05719  ITGB1, CD29; integrin beta 1
   05205 Proteoglycans in cancer
    K05719  ITGB1, CD29; integrin beta 1
   05222 Small cell lung cancer
    K05719  ITGB1, CD29; integrin beta 1
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K05719  ITGB1, CD29; integrin beta 1
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K05719  ITGB1, CD29; integrin beta 1
   05414 Dilated cardiomyopathy (DCM)
    K05719  ITGB1, CD29; integrin beta 1
  Infectious diseases
   05130 Pathogenic Escherichia coli infection
    K05719  ITGB1, CD29; integrin beta 1
   05131 Shigellosis
    K05719  ITGB1, CD29; integrin beta 1
   05133 Pertussis
    K05719  ITGB1, CD29; integrin beta 1
   05100 Bacterial invasion of epithelial cells
    K05719  ITGB1, CD29; integrin beta 1
   05165 Human papillomavirus infection
    K05719  ITGB1, CD29; integrin beta 1
   05145 Toxoplasmosis
    K05719  ITGB1, CD29; integrin beta 1
   05140 Leishmaniasis
    K05719  ITGB1, CD29; integrin beta 1
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    K05719  ITGB1, CD29; integrin beta 1
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K05719  ITGB1, CD29; integrin beta 1
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Neural system
   6/5 subfamily
    NRCAM; neuronal cell adhesion molecule
     VLA-4
      K05719 ITGB1, CD29; integrin beta 1
    L1CAM; L1 cell adhesion molecule
     VLA-5
      K05719 ITGB1, CD29; integrin beta 1
  Others
   VCAM1; vascular cell adhesion molecule 1
    VLA-4
     K05719 ITGB1, CD29; integrin beta 1
    VLA-9
     K05719 ITGB1, CD29; integrin beta 1
   ICAM4; intercellular adhesion molecule 4
    alpha V beta 1
     K05719 ITGB1, CD29; integrin beta 1
   LU; Lutheran blood group glycoprotein
    VLA-4
     K05719 ITGB1, CD29; integrin beta 1
   JAM2; junctional adhesion molecule 2
    VLA-4
     K05719 ITGB1, CD29; integrin beta 1
 2. Integrin Family
  Beta1 integrins
   VLA-2
    ITGB1; integrin beta 1
     VLA-3
      K05719 ITGB1, CD29; integrin beta 1
   VLA-3
    ITGB1; integrin beta 1
     VLA-2
      K05719 ITGB1, CD29; integrin beta 1
     VLA-3
      K05719 ITGB1, CD29; integrin beta 1
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type I classic cadherins
    CDHE, CDH1; cadherin 1, type 1, E-cadherin
     VLA-2
      K05719 ITGB1, CD29; integrin beta 1
  Clustered protocadherin
   PCDHA; protocadherin alpha
    VLA-5
     K05719 ITGB1, CD29; integrin beta 1
 7. Others
  TNFSF5, CD40L; tumor necrosis factor (ligand) superfamily, member 5
   VLA-5
    K05719 ITGB1, CD29; integrin beta 1
  SDC1; syndecan 1
   VLA-5
    K05719 ITGB1, CD29; integrin beta 1
  SDC4; syndecan 4
   VLA-5
    K05719 ITGB1, CD29; integrin beta 1
CD molecules [BR:ko04090]
 Proteins
  K05719  CD29, ITGB1; integrin, beta 1
BRITE hierarchy
Genes
HSA: 
3688(ITGB1)
PTR: 
450396(ITGB1)
PPS: 
100992059(ITGB1)
GGO: 
101142683(ITGB1)
PON: 
100172223(ITGB1)
NLE: 
100595108(ITGB1)
MCC: 
574312(ITGB1)
MCF: 
102144610(ITGB1)
CSAB: 
103238098(ITGB1)
RRO: 
104663301(ITGB1)
RBB: 
108529400(ITGB1)
CJC: 
100394145(ITGB1)
SBQ: 
101040620(ITGB1)
MMU: 
16412(Itgb1)
RNO: 
24511(Itgb1)
CGE: 
100763033(Itgb1)
NGI: 
103745645(Itgb1)
HGL: 
101711253(Itgb1)
CCAN: 
OCU: 
100008898(ITGB1)
TUP: 
102489284(ITGB1)
CFA: 
477956(ITGB1)
AML: 
100482697(ITGB1)
UMR: 
103656511(ITGB1)
ORO: 
101385291(ITGB1)
FCA: 
751821(ITGB1)
PTG: 
102967350(ITGB1)
AJU: 
106967340(ITGB1)
BTA: 
281876(ITGB1)
BOM: 
102273972(ITGB1)
BIU: 
109567924(ITGB1)
PHD: 
102315653(ITGB1)
CHX: 
102178060(ITGB1)
OAS: 
443141(ITGB1)
SSC: 
397019(ITGB1)
CFR: 
102509512(ITGB1)
CDK: 
105100650(ITGB1)
BACU: 
103008019(ITGB1)
LVE: 
103070821(ITGB1)
ECB: 
100055024(ITGB1)
EPZ: 
103565316(ITGB1)
EAI: 
106836617(ITGB1)
MYB: 
102260978(ITGB1)
MYD: 
102757018(ITGB1)
HAI: 
109388160(ITGB1)
RSS: 
109452639(ITGB1)
PALE: 
102886785(ITGB1)
LAV: 
100664978(ITGB1)
TMU: 
MDO: 
100018342(ITGB1)
SHR: 
100913968(ITGB1)
OAA: 
100073959(ITGB1)
GGA: 
374058(ITGB1)
MGP: 
100551464(ITGB1)
CJO: 
107308921(ITGB1)
APLA: 
101792849(ITGB1)
ACYG: 
TGU: 
100230947(ITGB1)
GFR: 
102039987(ITGB1)
FAB: 
101810282(ITGB1)
PHI: 
102112472(ITGB1)
PMAJ: 
107200467(ITGB1)
CCW: 
104686529(ITGB1)
FPG: 
101917395(ITGB1)
FCH: 
102059641(ITGB1)
CLV: 
102089491(ITGB1)
EGZ: 
104133604(ITGB1)
AAM: 
106489947(ITGB1)
ASN: 
102383871(ITGB1)
AMJ: 
102575802(ITGB1)
PSS: 
102452555(ITGB1)
CMY: 
102946836(ITGB1)
CPIC: 
101948025(ITGB1)
ACS: 
100562954(itgb1)
PVT: 
110082773(ITGB1)
PBI: 
103060558(ITGB1)
GJA: 
107125566(ITGB1)
XLA: 
397755(itgb1.L) 399443(itgb1.S)
XTR: 
394767(itgb1)
NPR: 
108792462(ITGB1)
DRE: 
405864(itgb1b.2) 556734(itgb1a) 570216(itgb1b)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
100304492(itgb1) 108271845(itgb1)
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
PRET: 
NFU: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
APLC: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD16875(Dsim_GD16875) Dsimw501_GD28212(Dsim_GD28212)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
CQU: 
AME: 
100576742 406097(GB19541) 724950(GB12005)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PMAC: 
PRAP: 
PXY: 
API: 
DNX: 
PHU: 
ZNE: 
FCD: 
DPX: 
ISC: 
TUT: 
CEL: 
CBR: 
CBG03601(Cbr-pat-3)
NAI: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
MYI: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
EPA: 
ADF: 
HMG: 
TAD: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2958481
  Authors
Argraves WS, Suzuki S, Arai H, Thompson K, Pierschbacher MD, Ruoslahti E
  Title
Amino acid sequence of the human fibronectin receptor.
  Journal
J Cell Biol 105:1183-90 (1987)
DOI:10.1083/jcb.105.3.1183
  Sequence
[hsa:3688]
Reference
PMID:7523423
  Authors
Balzac F, Retta SF, Albini A, Melchiorri A, Koteliansky VE, Geuna M, Silengo L, Tarone G
  Title
Expression of beta 1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motility.
  Journal
J Cell Biol 127:557-65 (1994)
DOI:10.1083/jcb.127.2.557

KEGG   ORTHOLOGY: K06493Help
Entry
K06493                      KO                                     

Name
ITGB3, CD61
Definition
integrin beta 3
Pathway
Rap1 signaling pathway
Phagosome
PI3K-Akt signaling pathway
Osteoclast differentiation
Focal adhesion
ECM-receptor interaction
Platelet activation
Hematopoietic cell lineage
Regulation of actin cytoskeleton
Thyroid hormone signaling pathway
Human papillomavirus infection
Proteoglycans in cancer
MicroRNAs in cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy (DCM)
Fluid shear stress and atherosclerosis
Disease
H00083  
Allograft rejection
H00226  
Glanzmann thrombasthenia
H01740  
Macrothrombocytopenia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K06493  ITGB3, CD61; integrin beta 3
   04151 PI3K-Akt signaling pathway
    K06493  ITGB3, CD61; integrin beta 3
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06493  ITGB3, CD61; integrin beta 3
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K06493  ITGB3, CD61; integrin beta 3
  Cellular community - eukaryotes
   04510 Focal adhesion
    K06493  ITGB3, CD61; integrin beta 3
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06493  ITGB3, CD61; integrin beta 3
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K06493  ITGB3, CD61; integrin beta 3
   04611 Platelet activation
    K06493  ITGB3, CD61; integrin beta 3
  Endocrine system
   04919 Thyroid hormone signaling pathway
    K06493  ITGB3, CD61; integrin beta 3
  Development
   04380 Osteoclast differentiation
    K06493  ITGB3, CD61; integrin beta 3
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K06493  ITGB3, CD61; integrin beta 3
   05205 Proteoglycans in cancer
    K06493  ITGB3, CD61; integrin beta 3
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K06493  ITGB3, CD61; integrin beta 3
   05410 Hypertrophic cardiomyopathy (HCM)
    K06493  ITGB3, CD61; integrin beta 3
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06493  ITGB3, CD61; integrin beta 3
   05414 Dilated cardiomyopathy (DCM)
    K06493  ITGB3, CD61; integrin beta 3
  Infectious diseases
   05165 Human papillomavirus infection
    K06493  ITGB3, CD61; integrin beta 3
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    K06493  ITGB3, CD61; integrin beta 3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06493  ITGB3, CD61; integrin beta 3
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Neural system
   6/5 subfamily
    L1CAM; L1 cell adhesion molecule
     VNR
      K06493 ITGB3, CD61; integrin beta 3
   N/0 subfamily
    THY1, CD90; Thy-1 cell surface antigen
     VNR
      K06493 ITGB3, CD61; integrin beta 3
  Others
   PECAM1, CD31; platelet/endothelial cell adhesion molecule
    VNR
     K06493 ITGB3, CD61; integrin beta 3
   ICAM4; intercellular adhesion molecule 4
    VNR
     K06493 ITGB3, CD61; integrin beta 3
    alpha IIb beta 3
     K06493 ITGB3, CD61; integrin beta 3
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type II classic cadherins
    CDH6; cadherin 6, type 2, K-cadherin
     alpha IIb  beta 3
      K06493 ITGB3, CD61; integrin beta 3
 7. Others
  TNFSF5, CD40L; tumor necrosis factor (ligand) superfamily, member 5
   alpha IIb beta 3
    K06493 ITGB3, CD61; integrin beta 3
  SDC1; syndecan 1
   VNR
    K06493 ITGB3, CD61; integrin beta 3
CD molecules [BR:ko04090]
 Proteins
  K06493  CD61, ITGB3; integrin, beta 3
BRITE hierarchy
Genes
HSA: 
3690(ITGB3)
PTR: 
468295(ITGB3)
PPS: 
100974497(ITGB3)
GGO: 
101149719(ITGB3)
PON: 
100445345(ITGB3)
NLE: 
100593791(ITGB3)
MCC: 
717379(ITGB3)
MCF: 
102117791(ITGB3)
CSAB: 
103243277(ITGB3)
RRO: 
104662513(ITGB3)
RBB: 
108536294(ITGB3)
CJC: 
100386042(ITGB3)
SBQ: 
101049562(ITGB3)
MMU: 
16416(Itgb3)
RNO: 
29302(Itgb3)
CGE: 
100775048(Itgb3)
NGI: 
103724762(Itgb3)
HGL: 
101715910(Itgb3)
CCAN: 
109696588(Itgb3)
OCU: 
100008735(ITGB3)
TUP: 
102486101(ITGB3)
CFA: 
403788(ITGB3)
AML: 
100476256(ITGB3)
UMR: 
103665892(ITGB3)
ORO: 
101369957(ITGB3)
FCA: 
101092159(ITGB3)
PTG: 
102963673(ITGB3)
AJU: 
106988847(ITGB3)
BTA: 
282642(ITGB3)
BOM: 
102268918(ITGB3)
BIU: 
109574140(ITGB3)
PHD: 
102334258(ITGB3)
CHX: 
102169417(ITGB3)
OAS: 
100423047(ITGB3)
SSC: 
397063(ITGB3)
CFR: 
102512014(ITGB3)
CDK: 
105090426(ITGB3)
BACU: 
103005345(ITGB3)
LVE: 
103070292(ITGB3)
ECB: 
100009709(ITGB3)
EPZ: 
103560746(ITGB3)
EAI: 
106843793(ITGB3)
MYB: 
102242014(ITGB3)
MYD: 
102761706(ITGB3)
HAI: 
109380323(ITGB3)
RSS: 
109448085(ITGB3)
PALE: 
102881894(ITGB3)
LAV: 
100660405(ITGB3)
TMU: 
MDO: 
100025359(ITGB3)
SHR: 
100920734(ITGB3)
OAA: 
GGA: 
374209(ITGB3)
MGP: 
100540307(ITGB3)
CJO: 
107325258(ITGB3)
APLA: 
101803666(ITGB3)
ACYG: 
106045987(ITGB3)
TGU: 
100226539(ITGB3)
GFR: 
102043377(ITGB3)
FAB: 
101806454(ITGB3)
PHI: 
102114571(ITGB3)
PMAJ: 
107215302(ITGB3)
CCW: 
104698490(ITGB3)
FPG: 
101924792(ITGB3)
FCH: 
102048772(ITGB3)
CLV: 
102089259(ITGB3)
EGZ: 
104134605(ITGB3)
AAM: 
ASN: 
102372699(ITGB3)
AMJ: 
102570288(ITGB3)
PSS: 
102444998(ITGB3)
CMY: 
CPIC: 
101953490(ITGB3)
ACS: 
PVT: 
110081384(ITGB3)
PBI: 
103060352(ITGB3)
GJA: 
XLA: 
397699(itgb3.L)
XTR: 
100498495(itgb3)
NPR: 
108797421(ITGB3)
DRE: 
100001836(itgb3b)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108274212(itgb3) 108279461(Itgb3)
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
PRET: 
NFU: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102349935(ITGB3)
CMK: 
103187732(itgb3)
CRG: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3494014
  Authors
Fitzgerald LA, Steiner B, Rall SC Jr, Lo SS, Phillips DR
  Title
Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to "integrin".
  Journal
J Biol Chem 262:3936-9 (1987)
  Sequence
[hsa:3690]
Reference
PMID:9195946
  Authors
Kumar CS, James IE, Wong A, Mwangi V, Feild JA, Nuthulaganti P, Connor JR, Eichman C, Ali F, Hwang SM, Rieman DJ, Drake FH, Gowen M
  Title
Cloning and characterization of a novel integrin beta3 subunit.
  Journal
J Biol Chem 272:16390-7 (1997)
DOI:10.1074/jbc.272.26.16390

KEGG   ORTHOLOGY: K06525Help
Entry
K06525                      KO                                     

Name
ITGB4, CD104
Definition
integrin beta 4
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Regulation of actin cytoskeleton
Human papillomavirus infection
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy (DCM)
Disease
H00586  
Epidermolysis bullosa, junctional
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06525  ITGB4, CD104; integrin beta 4
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06525  ITGB4, CD104; integrin beta 4
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K06525  ITGB4, CD104; integrin beta 4
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06525  ITGB4, CD104; integrin beta 4
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06525  ITGB4, CD104; integrin beta 4
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06525  ITGB4, CD104; integrin beta 4
   05414 Dilated cardiomyopathy (DCM)
    K06525  ITGB4, CD104; integrin beta 4
  Infectious diseases
   05165 Human papillomavirus infection
    K06525  ITGB4, CD104; integrin beta 4
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K06525  ITGB4, CD104; integrin beta 4
  Exosomal proteins of bladder cancer cells
   K06525  ITGB4, CD104; integrin beta 4
Cell adhesion molecules and their ligands [BR:ko04516]
 7. Others
  SDC1; syndecan 1
   alpha 6 beta 4
    K06525 ITGB4, CD104; integrin beta 4
  SDC4; syndecan 4
   alpha 6 beta 4
    K06525 ITGB4, CD104; integrin beta 4
CD molecules [BR:ko04090]
 Proteins
  K06525  CD104, ITGB4; integrin, beta 4
BRITE hierarchy
Genes
HSA: 
3691(ITGB4)
PTR: 
454887(ITGB4)
PPS: 
100986193(ITGB4)
GGO: 
PON: 
100453768(ITGB4)
NLE: 
100606975(ITGB4)
MCC: 
703770(ITGB4)
MCF: 
102132595(ITGB4)
CSAB: 
103243035(ITGB4)
RRO: 
104681299(ITGB4)
RBB: 
108537357(ITGB4)
CJC: 
100398837(ITGB4)
SBQ: 
101037393(ITGB4)
MMU: 
192897(Itgb4)
RNO: 
25724(Itgb4)
CGE: 
100756849(Itgb4)
NGI: 
103732717(Itgb4)
HGL: 
101697313(Itgb4)
CCAN: 
109695994(Itgb4)
OCU: 
100101587(ITGB4)
TUP: 
102488207(ITGB4)
CFA: 
483318(ITGB4)
AML: 
100469928(ITGB4)
UMR: 
103665746(ITGB4)
ORO: 
101384197(ITGB4)
FCA: 
101080415(ITGB4)
PTG: 
102948858(ITGB4)
AJU: 
106987780(ITGB4)
BTA: 
506995(ITGB4)
BOM: 
102288240(ITGB4)
BIU: 
109574049(ITGB4)
PHD: 
102327436(ITGB4)
CHX: 
102191175(ITGB4)
OAS: 
101119919(ITGB4)
SSC: 
100521988(ITGB4)
CFR: 
102513390(ITGB4)
CDK: 
105104653(ITGB4)
BACU: 
103016174(ITGB4)
LVE: 
103077180(ITGB4)
ECB: 
100051679(ITGB4)
EPZ: 
103546589(ITGB4)
EAI: 
106830304(ITGB4)
MYB: 
102260390(ITGB4)
MYD: 
102761395(ITGB4)
HAI: 
109383761(ITGB4)
RSS: 
109454713(ITGB4)
PALE: 
102898254(ITGB4)
LAV: 
100671877(ITGB4)
TMU: 
MDO: 
100027264(ITGB4)
SHR: 
100919163(ITGB4)
OAA: 
100090852(ITGB4)
GGA: 
417374(ITGB4)
MGP: 
100544044(ITGB4)
CJO: 
107322089(ITGB4)
APLA: 
101798901(ITGB4)
ACYG: 
106034721(ITGB4)
TGU: 
100231330(ITGB4)
GFR: 
102031672(ITGB4)
FAB: 
101809686(ITGB4)
PHI: 
102104162(ITGB4)
PMAJ: 
107212403(ITGB4)
CCW: 
104694382(ITGB4)
FPG: 
101923093(ITGB4)
FCH: 
102049446(ITGB4)
CLV: 
102087266(ITGB4)
EGZ: 
104125393(ITGB4)
AAM: 
106485674(ITGB4)
ASN: 
102379093(ITGB4)
AMJ: 
102562806(ITGB4)
PSS: 
102445383(ITGB4)
CMY: 
102937311(ITGB4)
CPIC: 
101940932(ITGB4)
ACS: 
100556105(itgb4)
PVT: 
110085179(ITGB4)
PBI: 
103048232(ITGB4)
GJA: 
107113186(ITGB4)
XLA: 
108701118(itgb4.L) 108702819(itgb4.S)
XTR: 
100485847(itgb4)
NPR: 
108791154(ITGB4)
DRE: 
335269(itgb4)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108265318(itgb4)
AMEX: 
103047644(itgb4)
TRU: 
101073040(itgb4)
TNG: 
LCO: 
104924907(itgb4)
NCC: 
MZE: 
101465287(itgb4)
OLA: 
101158429(itgb4)
XMA: 
102232649(itgb4)
PRET: 
NFU: 
107388303(itgb4)
CSEM: 
103382112(itgb4)
LCF: 
108872502(itgb4)
HCQ: 
109513294(itgb4)
BPEC: 
110155181(itgb4)
SASA: 
ELS: 
105023024(itgb4)
SFM: 
108939918(itgb4)
LCM: 
102353222(ITGB4)
CMK: 
103175434(itgb4)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2311577
  Authors
Suzuki S, Naitoh Y
  Title
Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells.
  Journal
EMBO J 9:757-63 (1990)
  Sequence
[hsa:3691]
Reference
  Authors
Koster J, Geerts D, Favre B, Borradori L, Sonnenberg A
  Title
Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.
  Journal
J Cell Sci 116:387-99 (2003)
DOI:10.1242/jcs.00241

KEGG   ORTHOLOGY: K06588Help
Entry
K06588                      KO                                     

Name
ITGB5
Definition
integrin beta 5
Pathway
Phagosome
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Regulation of actin cytoskeleton
Human papillomavirus infection
Proteoglycans in cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06588  ITGB5; integrin beta 5
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06588  ITGB5; integrin beta 5
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K06588  ITGB5; integrin beta 5
  Cellular community - eukaryotes
   04510 Focal adhesion
    K06588  ITGB5; integrin beta 5
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06588  ITGB5; integrin beta 5
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K06588  ITGB5; integrin beta 5
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06588  ITGB5; integrin beta 5
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06588  ITGB5; integrin beta 5
   05414 Dilated cardiomyopathy (DCM)
    K06588  ITGB5; integrin beta 5
  Infectious diseases
   05165 Human papillomavirus infection
    K06588  ITGB5; integrin beta 5
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    K06588  ITGB5; integrin beta 5
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Others
   ICAM4; intercellular adhesion molecule 4
    alpha V beta 5
     K06588 ITGB5; integrin beta 5
 7. Others
  SDC1; syndecan 1
   alpha V beta 5
    K06588 ITGB5; integrin beta 5
BRITE hierarchy
Genes
HSA: 
3693(ITGB5)
PTR: 
460646(ITGB5)
PPS: 
100979758(ITGB5)
GGO: 
101127698(ITGB5)
PON: 
100449826(ITGB5)
NLE: 
100592156(ITGB5)
MCC: 
715710(ITGB5)
MCF: 
102123619(ITGB5)
CSAB: 
103228149(ITGB5)
RRO: 
104655400(ITGB5)
RBB: 
108517420(ITGB5)
CJC: 
100395279(ITGB5)
SBQ: 
101029859(ITGB5)
MMU: 
16419(Itgb5)
RNO: 
257645(Itgb5)
CGE: 
100765378(Itgb5)
NGI: 
103741999(Itgb5)
HGL: 
101702445(Itgb5)
CCAN: 
OCU: 
100353546(ITGB5)
TUP: 
102489381(ITGB5)
CFA: 
608977(ITGB5)
AML: 
100476382(ITGB5)
UMR: 
103678821(ITGB5)
ORO: 
101376952(ITGB5)
FCA: 
101101247(ITGB5)
PTG: 
102969248(ITGB5)
AJU: 
106984073(ITGB5)
BTA: 
282564(ITGB5)
BOM: 
102270944(ITGB5)
BIU: 
109555956(ITGB5)
PHD: 
102342431(ITGB5)
CHX: 
102173608(ITGB5)
OAS: 
101120887(ITGB5)
SSC: 
100134977(ITGB5)
CFR: 
102524464(ITGB5)
CDK: 
105090274(ITGB5)
BACU: 
103010943(ITGB5)
LVE: 
103089053(ITGB5)
ECB: 
100070376(ITGB5)
EPZ: 
103547475(ITGB5)
EAI: 
106847529(ITGB5)
MYB: 
102262191(ITGB5)
MYD: 
102754300(ITGB5)
HAI: 
109387967(ITGB5)
RSS: 
109451059(ITGB5)
PALE: 
102892062(ITGB5)
LAV: 
100676335(ITGB5)
TMU: 
MDO: 
100020074(ITGB5)
SHR: 
100932177(ITGB5)
GGA: 
395142(ITGB5)
MGP: 
104911802(ITGB5)
CJO: 
107316778(ITGB5)
APLA: 
101795907(ITGB5)
ACYG: 
106029904(ITGB5)
TGU: 
100222654(ITGB5)
GFR: 
102045444(ITGB5)
FAB: 
101807892(ITGB5)
PHI: 
102106421(ITGB5)
PMAJ: 
107207337(ITGB5)
CCW: 
104694025(ITGB5)
FPG: 
101923809(ITGB5)
FCH: 
102048115(ITGB5)
CLV: 
102096917(ITGB5)
EGZ: 
104128131(ITGB5)
AAM: 
ASN: 
102373539(ITGB5)
AMJ: 
102563470(ITGB5)
PSS: 
102460733(ITGB5)
CMY: 
102947437(ITGB5)
CPIC: 
101952519(ITGB5)
ACS: 
100557339(itgb5)
PVT: 
110090759(ITGB5)
PBI: 
103054002(ITGB5)
GJA: 
107106324(ITGB5)
XLA: 
108702890(itgb5.S) 446423(itgb5.L)
XTR: 
100216279(itgb5)
NPR: 
108791265(ITGB5)
DRE: 
563556(itgb5)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108266628(itgb5)
AMEX: 
103047818(itgb5)
TRU: 
101079123(itgb5)
TNG: 
LCO: 
104926275(itgb5)
MZE: 
101463607(itgb5)
OLA: 
101165543(itgb5)
XMA: 
102223398(itgb5)
PRET: 
103482002(itgb5)
NFU: 
107389558(itgb5)
CSEM: 
103391620(itgb5)
LCF: 
108902467(itgb5)
HCQ: 
109520005(itgb5)
BPEC: 
110170582(itgb5)
SASA: 
ELS: 
105016113(itgb5)
SFM: 
108930200(itgb5)
LCM: 
102360569(ITGB5)
CMK: 
103176393(itgb5)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2328726
  Authors
Ramaswamy H, Hemler ME
  Title
Cloning, primary structure and properties of a novel human integrin beta subunit.
  Journal
EMBO J 9:1561-8 (1990)
  Sequence
[hsa:3693]
Reference
  Authors
Lyle C, McCormick F
  Title
Integrin alphavbeta5 is a primary receptor for adenovirus in CAR-negative cells.
  Journal
Virol J 7:148 (2010)
DOI:10.1186/1743-422X-7-148

KEGG   ORTHOLOGY: K06589Help
Entry
K06589                      KO                                     

Name
ITGB6
Definition
integrin beta 6
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Regulation of actin cytoskeleton
Human papillomavirus infection
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy (DCM)
Disease
H00615  
Amelogenesis imperfecta
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06589  ITGB6; integrin beta 6
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06589  ITGB6; integrin beta 6
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K06589  ITGB6; integrin beta 6
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06589  ITGB6; integrin beta 6
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06589  ITGB6; integrin beta 6
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06589  ITGB6; integrin beta 6
   05414 Dilated cardiomyopathy (DCM)
    K06589  ITGB6; integrin beta 6
  Infectious diseases
   05165 Human papillomavirus infection
    K06589  ITGB6; integrin beta 6
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of epithelial cells
   K06589  ITGB6; integrin beta 6
BRITE hierarchy
Genes
HSA: 
3694(ITGB6)
PTR: 
459683(ITGB6)
PPS: 
100987022(ITGB6)
GGO: 
101135367(ITGB6)
PON: 
100171913(ITGB6)
NLE: 
100601748(ITGB6)
MCC: 
700454(ITGB6)
MCF: 
102122296(ITGB6)
CSAB: 
103217169(ITGB6)
RRO: 
104674711(ITGB6)
RBB: 
108527702(ITGB6)
CJC: 
100401625(ITGB6)
SBQ: 
101045524(ITGB6)
MMU: 
16420(Itgb6)
RNO: 
311061(Itgb6)
CGE: 
100768511(Itgb6)
NGI: 
103744081(Itgb6)
HGL: 
101701540(Itgb6)
CCAN: 
109694161(Itgb6)
OCU: 
100338232(ITGB6)
TUP: 
102485830(ITGB6)
CFA: 
488368(ITGB6)
AML: 
100471721(ITGB6)
UMR: 
103659497(ITGB6)
ORO: 
101366733(ITGB6)
FCA: 
101094363(ITGB6)
PTG: 
102949682(ITGB6)
AJU: 
106984682(ITGB6)
BTA: 
282644(ITGB6)
BOM: 
102285344(ITGB6)
BIU: 
109567207(ITGB6)
PHD: 
102330616(ITGB6)
CHX: 
102188539(ITGB6)
OAS: 
443209(ITGB6)
SSC: 
100037276(ITGB6)
CFR: 
102516154(ITGB6)
CDK: 
105093695(ITGB6)
BACU: 
103009431(ITGB6)
LVE: 
103082310(ITGB6)
ECB: 
100051266(ITGB6)
EPZ: 
103546835(ITGB6)
EAI: 
106843040(ITGB6)
MYB: 
102249275(ITGB6)
MYD: 
102758665(ITGB6)
HAI: 
109379873(ITGB6)
RSS: 
109445158(ITGB6)
PALE: 
102885280(ITGB6)
LAV: 
100664907(ITGB6)
TMU: 
MDO: 
100022034(ITGB6)
SHR: 
100913762(ITGB6)
OAA: 
100081941(ITGB6)
GGA: 
424191(ITGB6)
MGP: 
100548345(ITGB6)
CJO: 
107317016(ITGB6)
APLA: 
101796767(ITGB6)
ACYG: 
106029926(ITGB6)
TGU: 
100226511(ITGB6)
GFR: 
102038988(ITGB6)
FAB: 
101811524(ITGB6)
PHI: 
102105914(ITGB6)
PMAJ: 
107207823(ITGB6)
CCW: 
104693933(ITGB6)
FPG: 
101915498(ITGB6)
FCH: 
102050584(ITGB6)
CLV: 
102089659(ITGB6)
EGZ: 
104128819(ITGB6)
AAM: 
106499136(ITGB6)
ASN: 
102376186(ITGB6)
AMJ: 
106736963(ITGB6)
PSS: 
102456822(ITGB6)
CMY: 
102945711(ITGB6)
CPIC: 
101951190(ITGB6)
ACS: 
100562379(itgb6)
PVT: 
110081565(ITGB6)
PBI: 
103067112(ITGB6)
GJA: 
107126129(ITGB6)
XLA: 
378686(itgb6.L)
XTR: 
100037861(itgb6)
NPR: 
108799786(ITGB6)
DRE: 
100499533(itgb6)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108270759(itgb6)
AMEX: 
TRU: 
101072262(itgb6)
TNG: 
LCO: 
104918253(itgb6)
NCC: 
104967076(itgb6)
MZE: 
101471632(itgb6)
OLA: 
101157680(itgb6)
XMA: 
102237167(itgb6)
PRET: 
103462005(itgb6)
NFU: 
107381662(itgb6)
CSEM: 
103378678(itgb6)
LCF: 
108887971(itgb6)
HCQ: 
109525832(itgb6)
BPEC: 
110172827(itgb6)
SASA: 
ELS: 
105019946(itgb6)
SFM: 
108927878(itgb6)
LCM: 
102346959(ITGB6)
CMK: 
103176359(itgb6)
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2365683
  Authors
Sheppard D, Rozzo C, Starr L, Quaranta V, Erle DJ, Pytela R
  Title
Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.
  Journal
J Biol Chem 265:11502-7 (1990)
  Sequence
[hsa:3694]
Reference
PMID:9426447
  Authors
Agrez MV, Shafren DR, Gu X, Cox K, Sheppard D, Barry RD
  Title
Integrin alpha v beta 6 enhances coxsackievirus B1 lytic infection of human colon cancer cells.
  Journal
Virology 239:71-7 (1997)
DOI:10.1006/viro.1997.8831

KEGG   ORTHOLOGY: K06590Help
Entry
K06590                      KO                                     

Name
ITGB7
Definition
integrin beta 7
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Intestinal immune network for IgA production
Regulation of actin cytoskeleton
Human papillomavirus infection
Transcriptional misregulation in cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06590  ITGB7; integrin beta 7
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06590  ITGB7; integrin beta 7
   04514 Cell adhesion molecules (CAMs)
    K06590  ITGB7; integrin beta 7
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K06590  ITGB7; integrin beta 7
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06590  ITGB7; integrin beta 7
 Organismal Systems
  Immune system
   04672 Intestinal immune network for IgA production
    K06590  ITGB7; integrin beta 7
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K06590  ITGB7; integrin beta 7
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06590  ITGB7; integrin beta 7
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06590  ITGB7; integrin beta 7
   05414 Dilated cardiomyopathy (DCM)
    K06590  ITGB7; integrin beta 7
  Infectious diseases
   05165 Human papillomavirus infection
    K06590  ITGB7; integrin beta 7
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06590  ITGB7; integrin beta 7
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Others
   VCAM1; vascular cell adhesion molecule 1
    alpha 4 beta7
     K06590 ITGB7; integrin beta 7
   MADCAM1; mucosal vascular addressin cell adhesion molecule 1
    alpha 4 beta7
     K06590 ITGB7; integrin beta 7
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type I classic cadherins
    CDHE, CDH1; cadherin 1, type 1, E-cadherin
     alpha E beta 7
      K06590 ITGB7; integrin beta 7
BRITE hierarchy
Genes
HSA: 
3695(ITGB7)
PTR: 
451934(ITGB7)
PPS: 
100989804(ITGB7)
GGO: 
101145271(ITGB7)
PON: 
100440010(ITGB7)
NLE: 
100590097(ITGB7)
MCC: 
699405(ITGB7)
MCF: 
102137082(ITGB7)
CSAB: 
103238384(ITGB7)
RRO: 
104670606(ITGB7)
RBB: 
108521588(ITGB7)
CJC: 
100402863(ITGB7)
SBQ: 
101028462(ITGB7)
MMU: 
16421(Itgb7)
RNO: 
25713(Itgb7)
CGE: 
100770075(Itgb7)
NGI: 
103738472(Itgb7)
HGL: 
101719620(Itgb7)
CCAN: 
109684070(Itgb7)
OCU: 
100350557(ITGB7)
TUP: 
102469446(ITGB7)
CFA: 
477598(ITGB7)
AML: 
100474212(ITGB7)
UMR: 
103675667(ITGB7)
ORO: 
101371307(ITGB7)
FCA: 
101099982(ITGB7)
PTG: 
102956549(ITGB7)
AJU: 
106986437(ITGB7)
BTA: 
514031(ITGB7)
BOM: 
102285452(ITGB7)
BIU: 
109559043(ITGB7)
PHD: 
102343070(ITGB7)
CHX: 
102180190(ITGB7)
OAS: 
101109956(ITGB7)
CFR: 
102509667(ITGB7)
CDK: 
105094574(ITGB7)
BACU: 
103006205(ITGB7)
LVE: 
103081453(ITGB7)
ECB: 
100063747(ITGB7)
EPZ: 
103559421(ITGB7)
EAI: 
106835324(ITGB7)
MYB: 
MYD: 
102754396(ITGB7)
HAI: 
109391828(ITGB7)
RSS: 
109443745(ITGB7)
PALE: 
102896485(ITGB7)
LAV: 
100661118(ITGB7)
TMU: 
SHR: 
100920489(ITGB7)
GGA: 
CJO: 
107306950(ITGB7)
ASN: 
102378313(ITGB7)
AMJ: 
102573931(ITGB7)
PSS: 
102459674(ITGB7)
CMY: 
102934106(ITGB7)
CPIC: 
101940453(ITGB7)
ACS: 
100566599(itgb7)
PVT: 
110070338(ITGB7)
PBI: 
103048661(ITGB7)
GJA: 
107118966(ITGB7)
XLA: 
108708650(itgb7.L)
XTR: 
100486332(itgb7)
NPR: 
108786823(ITGB7)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
AMEX: 
SASA: 
ELS: 
SFM: 
LCM: 
102367083(ITGB7)
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2083230
  Authors
Yuan QA, Jiang WM, Krissansen GW, Watson JD
  Title
Cloning and sequence analysis of a novel beta 2-related integrin transcript from T lymphocytes: homology of integrin cysteine-rich repeats to domain III of laminin B chains.
  Journal
Int Immunol 2:1097-108 (1990)
DOI:10.1093/intimm/2.11.1097
  Sequence
[hsa:3695]
Reference
  Authors
Cicala C, Martinelli E, McNally JP, Goode DJ, Gopaul R, Hiatt J, Jelicic K, Kottilil S, Macleod K, O'Shea A, Patel N, Van Ryk D, Wei D, Pascuccio M, Yi L, McKinnon L, Izulla P, Kimani J, Kaul R, Fauci AS, Arthos J
  Title
The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.
  Journal
Proc Natl Acad Sci U S A 106:20877-82 (2009)
DOI:10.1073/pnas.0911796106

KEGG   ORTHOLOGY: K06591Help
Entry
K06591                      KO                                     

Name
ITGB8
Definition
integrin beta 8
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Regulation of actin cytoskeleton
Human papillomavirus infection
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06591  ITGB8; integrin beta 8
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06591  ITGB8; integrin beta 8
   04514 Cell adhesion molecules (CAMs)
    K06591  ITGB8; integrin beta 8
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K06591  ITGB8; integrin beta 8
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06591  ITGB8; integrin beta 8
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06591  ITGB8; integrin beta 8
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06591  ITGB8; integrin beta 8
   05414 Dilated cardiomyopathy (DCM)
    K06591  ITGB8; integrin beta 8
  Infectious diseases
   05165 Human papillomavirus infection
    K06591  ITGB8; integrin beta 8
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K06591  ITGB8; integrin beta 8
BRITE hierarchy
Genes
HSA: 
3696(ITGB8)
PTR: 
PPS: 
100970723(ITGB8)
GGO: 
101147846(ITGB8)
PON: 
100459025(ITGB8)
NLE: 
100589408(ITGB8)
MCC: 
707247(ITGB8)
MCF: 
102116742(ITGB8)
CSAB: 
103226407(ITGB8)
RRO: 
104658643(ITGB8)
RBB: 
108529317(ITGB8)
CJC: 
100401019(ITGB8)
SBQ: 
101039828(ITGB8)
MMU: 
320910(Itgb8)
RNO: 
362800(Itgb8)
CGE: 
100769713(Itgb8)
NGI: 
103733702(Itgb8)
HGL: 
101703316(Itgb8)
CCAN: 
OCU: 
100009141(ITGB8)
TUP: 
102495199(ITGB8)
CFA: 
475253(ITGB8)
AML: 
100468149(ITGB8)
UMR: 
103658858(ITGB8)
ORO: 
101374393(ITGB8)
FCA: 
101087724(ITGB8)
PTG: 
102970624(ITGB8)
AJU: 
106982217(ITGB8)
BTA: 
536286(ITGB8)
BOM: 
102283263(ITGB8)
BIU: 
109557291(ITGB8)
PHD: 
102338048(ITGB8)
CHX: 
102191301(ITGB8)
OAS: 
101107517(ITGB8)
SSC: 
100037284(ITGB8)
CFR: 
102518839(ITGB8)
CDK: 
105092896(ITGB8)
BACU: 
103005840(ITGB8)
LVE: 
103090223(ITGB8)
ECB: 
100053462(ITGB8)
EPZ: 
103559760(ITGB8)
EAI: 
106824352(ITGB8)
MYB: 
102246659(ITGB8)
MYD: 
102762898(ITGB8)
HAI: 
109386990(ITGB8)
RSS: 
109445237(ITGB8)
PALE: 
102893900(ITGB8)
LAV: 
100661984(ITGB8)
TMU: 
MDO: 
100018731(ITGB8)
SHR: 
100931776(ITGB8)
OAA: 
100083540(ITGB8)
GGA: 
395470(ITGB8)
MGP: 
100540683(ITGB8)
CJO: 
107309198(ITGB8)
APLA: 
101797604(ITGB8)
ACYG: 
106030178(ITGB8)
TGU: 
100232167(ITGB8)
GFR: 
102035625(ITGB8)
FAB: 
101806937(ITGB8)
PHI: 
102110187(ITGB8)
PMAJ: 
107200580(ITGB8)
CCW: 
104689120(ITGB8)
FPG: 
101918459(ITGB8)
FCH: 
102059714(ITGB8)
CLV: 
102094007(ITGB8)
EGZ: 
104126160(ITGB8)
AAM: 
106483431(ITGB8)
ASN: 
102380004(ITGB8)
AMJ: 
102563842(ITGB8)
PSS: 
102448463(ITGB8)
CMY: 
102938213(ITGB8)
CPIC: 
101938854(ITGB8)
ACS: 
100566496(itgb8)
PVT: 
110072726(ITGB8)
PBI: 
GJA: 
107123057(ITGB8)
XLA: 
108718868(itgb8.L) 108719918(itgb8.S)
XTR: 
100494899(itgb8)
NPR: 
108804525(ITGB8)
DRE: 
556752(itgb8)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108257400(itgb8)
AMEX: 
103039055(itgb8)
TRU: 
101077495(itgb8)
TNG: 
LCO: 
104936837(itgb8)
NCC: 
MZE: 
101468369(itgb8)
OLA: 
101167379(itgb8)
XMA: 
102229338(itgb8)
PRET: 
NFU: 
107383328(itgb8)
CSEM: 
103394627(itgb8)
LCF: 
108877780(itgb8)
HCQ: 
109513513(itgb8)
BPEC: 
110167428(itgb8)
SASA: 
ELS: 
105012465(itgb8)
SFM: 
108933444(itgb8)
LCM: 
102345380(ITGB8)
CMK: 
103185062(itgb8)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1918072
  Authors
Moyle M, Napier MA, McLean JW
  Title
Cloning and expression of a divergent integrin subunit beta 8.
  Journal
J Biol Chem 266:19650-8 (1991)
  Sequence
[hsa:3696]
Reference
  Authors
Reyes SB, Narayanan AS, Lee HS, Tchaicha JH, Aldape KD, Lang FF, Tolias KF, McCarty JH
  Title
alphavbeta8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion.
  Journal
Mol Biol Cell 24:474-82 (2013)
DOI:10.1091/mbc.E12-07-0521

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