KEGG   ORTHOLOGY: K05854Help
Entry
K05854                      KO                                     

Name
LYN
Definition
tyrosine-protein kinase Lyn [EC:2.7.10.2]
Pathway
Chemokine signaling pathway
NF-kappa B signaling pathway
Platelet activation
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Long-term depression
Epithelial cell signaling in Helicobacter pylori infection
Kaposi's sarcoma-associated herpesvirus infection
Epstein-Barr virus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K05854  LYN; tyrosine-protein kinase Lyn
 Organismal Systems
  Immune system
   04611 Platelet activation
    K05854  LYN; tyrosine-protein kinase Lyn
   04662 B cell receptor signaling pathway
    K05854  LYN; tyrosine-protein kinase Lyn
   04664 Fc epsilon RI signaling pathway
    K05854  LYN; tyrosine-protein kinase Lyn
   04666 Fc gamma R-mediated phagocytosis
    K05854  LYN; tyrosine-protein kinase Lyn
   04062 Chemokine signaling pathway
    K05854  LYN; tyrosine-protein kinase Lyn
  Nervous system
   04730 Long-term depression
    K05854  LYN; tyrosine-protein kinase Lyn
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K05854  LYN; tyrosine-protein kinase Lyn
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K05854  LYN; tyrosine-protein kinase Lyn
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K05854  LYN; tyrosine-protein kinase Lyn
   05169 Epstein-Barr virus infection
    K05854  LYN; tyrosine-protein kinase Lyn
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K05854  LYN; tyrosine-protein kinase Lyn
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  Src family
   K05854  LYN; tyrosine-protein kinase Lyn
Membrane trafficking [BR:ko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    K05854  LYN; tyrosine-protein kinase Lyn
BRITE hierarchy
Other DBs
Genes
HSA: 
4067(LYN)
PTR: 
472771(LYN)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
698553(LYN)
MCF: 
CSAB: 
RRO: 
RBB: 
CJC: 
SBQ: 
MMU: 
17096(Lyn) 666513(Gm11787)
RNO: 
81515(Lyn)
CGE: 
NGI: 
HGL: 
CCAN: 
OCU: 
TUP: 
CFA: 
477886(LYN)
AML: 
UMR: 
FCA: 
PTG: 
AJU: 
BTA: 
534996(LYN)
BOM: 
BIU: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
CDK: 
BACU: 
LVE: 
ECB: 
EPZ: 
EAI: 
MYB: 
MYD: 
HAI: 
RSS: 
PALE: 
LAV: 
MDO: 
SHR: 
OAA: 
GGA: 
421127(LYN)
MGP: 
CJO: 
APLA: 
ACYG: 
TGU: 
GFR: 
FAB: 
PHI: 
PMAJ: 
CCW: 
FPG: 
FCH: 
CLV: 
AAM: 
ASN: 
AMJ: 
PSS: 
CMY: 
CPIC: 
ACS: 
PVT: 
PBI: 
GJA: 
XLA: 
108695301(lyn.S) 373649(lyn.L)
XTR: 
549989(lyn)
NPR: 
DRE: 
447804(lyn)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3561390
  Authors
Yamanashi Y, Fukushige S, Semba K, Sukegawa J, Miyajima N, Matsubara K, Yamamoto T, Toyoshima K
  Title
The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck.
  Journal
Mol Cell Biol 7:237-43 (1987)
DOI:10.1128/MCB.7.1.237
  Sequence
[hsa:4067]
Reference
  Authors
Gaul BS, Harrison ML, Geahlen RL, Burton RA, Post CB
  Title
Substrate recognition by the Lyn protein-tyrosine kinase. NMR structure of the immunoreceptor tyrosine-based activation motif signaling region of the B cell antigen receptor.
  Journal
J Biol Chem 275:16174-82 (2000)
DOI:10.1074/jbc.M909044199

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