KEGG   ORTHOLOGY: K07197Help
Entry
K07197                      KO                                     

Name
SREBP1, SREBF1
Definition
sterol regulatory element-binding transcription factor 1
Pathway
ko04152  AMPK signaling pathway
ko04910  Insulin signaling pathway
ko04931  Insulin resistance
ko04932  Non-alcoholic fatty liver disease (NAFLD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04152 AMPK signaling pathway
    K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
 Human Diseases
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
   04931 Insulin resistance
    K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Ubiquitous bHLH-ZIP factors
    K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
Membrane trafficking [BR:ko04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
BRITE hierarchy
Genes
HSA: 6720(SREBF1)
PTR: 454480(SREBF1)
PPS: 100974159(SREBF1)
GGO: 101154562(SREBF1)
PON: 100438806(SREBF1)
NLE: 100591724(SREBF1)
MCC: 706972(SREBF1)
MCF: 102140831(SREBF1)
CSAB: 103242479(SREBF1)
RRO: 104665664(SREBF1)
RBB: 108544463(SREBF1)
CJC: 100405845(SREBF1)
SBQ: 101029259(SREBF1)
MMU: 20787(Srebf1)
RNO: 78968(Srebf1)
CGE: 100689018(Srebf1)
NGI: 103724841(Srebf1)
HGL: 101705277(Srebf1)
CCAN: 109701447(Srebf1)
OCU: 103346501(SREBF1)
TUP: 102484139(SREBF1)
CFA: 403475(SREBF1)
AML: 100476071(SREBF1)
UMR: 103658535(SREBF1)
ORO: 101373569(SREBF1)
FCA: 101087535(SREBF1)
PTG: 102967397(SREBF1)
AJU: 106981387(SREBF1)
BTA: 539361(SREBF1)
BOM: 102272556(SREBF1)
BIU: 109573629(SREBF1)
PHD: 102334617(SREBF1)
CHX: 100860908(SREBF1) 108635517
OAS: 100329218(SREBF1)
SSC: 397308(SREBF1)
CFR: 102511046(SREBF1)
CDK: 105100581(SREBF1)
BACU: 103011610(SREBF1)
LVE: 103071798(SREBF1)
OOR: 101272079(SREBF1)
ECB: 100052283(SREBF1)
EPZ: 103566435(SREBF1)
EAI: 106840596(SREBF1)
MYB: 102255796(SREBF1)
MYD: 102767914(SREBF1)
HAI: 109390325(SREBF1)
RSS: 109436859(SREBF1)
PALE: 102882131(SREBF1)
LAV: 100653881(SREBF1)
TMU: 101352805
MDO: 100029730(SREBF1)
SHR: 100913395(SREBF1)
OAA: 100079611(SREBF1)
GGA: 373915(SREBF1)
MGP: 100543534(SREBF1)
CJO: 107320619(SREBF1)
TGU: 100221184(SREBF1)
GFR: 102034801(SREBF1)
FAB: 101816525(SREBF1)
PHI: 102111817(SREBF1)
PMAJ: 107211194(SREBF1)
CCW: 104685021(SREBF1)
FPG: 101920211(SREBF1)
FCH: 102059224(SREBF1)
CLV: 102096606(SREBF1)
EGZ: 104123591(SREBF1)
AAM: 106485067(SREBF1)
ASN: 102380092(SREBF1)
AMJ: 102575658(SREBF1)
PSS: 102454387(SREBF1)
CMY: 102946183(SREBF1)
CPIC: 101949383(SREBF1) 103307498
ACS: 100567358(srebf1)
PVT: 110090325(SREBF1)
PBI: 103054943 103064964(SREBF1)
GJA: 107124247(SREBF1)
XLA: 108701685 108703239(srebf1.S)
XTR: 100485631(srebf1)
NPR: 108788747
DRE: 793274(srebf1)
SRX: 107713935 107724733(srebf1)
SANH: 107662509(srebf1) 107691218
SGH: 107555671(srebf1) 107559518
CCAR: 109056082 109056088(srebf1)
IPU: 108256078(srebf1)
AMEX: 103027171(srebf1)
TRU: 101070738(srebf1)
LCO: 104918839(srebf1)
NCC: 104957712(srebf1)
MZE: 101476344(srebf1)
OLA: 101163083(srebf1)
XMA: 102233782(srebf1)
PRET: 103469249(srebf1)
NFU: 107376556(srebf1)
CSEM: 103393095(srebf1)
LCF: 108879904(srebf1) 108894857
HCQ: 109522738(srebf1)
BPEC: 110171451(srebf1)
ELS: 105013003(srebf1)
LCM: 102349558(SREBF1)
CMK: 103186611(srebf1)
SPU: 590876
APLC: 110988878
SKO: 100313740(SREB)
DME: Dmel_CG8522(SREBP)
DPO: Dpse_GA21134(Dpse_SREBP)
DAN: Dana_GF23590(Dana_SREBP)
DER: Dere_GG16056(Dere_SREBP)
DSI: Dsimw501_GD14826(Dsim_GD14826)
DWI: Dwil_GK17496(Dwil_SREBP)
DYA: Dyak_GE19622(Dyak_SREBP)
DMO: Dmoj_GI11638(Dmoj_SREBP)
DVI: Dvir_GJ11320(Dvir_SREBP)
MDE: 101900785
AAG: 5573523
AME: 413422
BIM: 100750005
BTER: 100652148
SOC: 105199149
AEC: 105151412
ACEP: 105617217
PBAR: 105433716
HST: 105182216
CFO: 105251410
LHU: 105673619
PGC: 109856002
NVI: 100124259
TCA: 663039
DPA: 109538803
NVL: 108557039
BMOR: 101743180
PMAC: 106708898
PRAP: 110998524
PXY: 105392526
API: 100164413
DNX: 107170425
ZNE: 110837451
FCD: 110847213
CRG: 105345607
MYI: 110457610
OBI: 106873465
LAK: 106158965
EPA: 110248868
ADF: 107328115
AQU: 100640588
MBR: MONBRDRAFT_32649(Mb_HLH_10)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Hagen RM, Rodriguez-Cuenca S, Vidal-Puig A
  Title
An allostatic control of membrane lipid composition by SREBP1.
  Journal
FEBS Lett 584:2689-98 (2010)
DOI:10.1016/j.febslet.2010.04.004
  Sequence
[hsa:6720]

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