Entry
Symbol
FOXO1
Name
Pathway
map04213 Longevity regulating pathway - multiple species
map04919 Thyroid hormone signaling pathway
map04933 AGE-RAGE signaling pathway in diabetic complications
map05202 Transcriptional misregulation in cancer
Disease
H02434 Diffuse large B-cell lymphoma, not otherwise specified
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
K07201 FOXO1; forkhead box protein O1
04152 AMPK signaling pathway
K07201 FOXO1; forkhead box protein O1
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
K07201 FOXO1; forkhead box protein O1
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
K07201 FOXO1; forkhead box protein O1
04922 Glucagon signaling pathway
K07201 FOXO1; forkhead box protein O1
04919 Thyroid hormone signaling pathway
K07201 FOXO1; forkhead box protein O1
09149 Aging
04211 Longevity regulating pathway
K07201 FOXO1; forkhead box protein O1
04213 Longevity regulating pathway - multiple species
K07201 FOXO1; forkhead box protein O1
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K07201 FOXO1; forkhead box protein O1
05202 Transcriptional misregulation in cancer
K07201 FOXO1; forkhead box protein O1
09162 Cancer: specific types
05215 Prostate cancer
K07201 FOXO1; forkhead box protein O1
09172 Infectious disease: viral
05165 Human papillomavirus infection
K07201 FOXO1; forkhead box protein O1
09171 Infectious disease: bacterial
05131 Shigellosis
K07201 FOXO1; forkhead box protein O1
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
K07201 FOXO1; forkhead box protein O1
04931 Insulin resistance
K07201 FOXO1; forkhead box protein O1
04933 AGE-RAGE signaling pathway in diabetic complications
K07201 FOXO1; forkhead box protein O1
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors
K07201 FOXO1; forkhead box protein O1
Transcription factors [BR:ko03000 ]
Eukaryotic type
Helix-turn-helix
Fork head/winged helix other regulators
K07201 FOXO1; forkhead box protein O1
BRITE hierarchy
Genes
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Taxonomy UniProt
Reference
Authors
Bois PR, Izeradjene K, Houghton PJ, Cleveland JL, Houghton JA, Grosveld GC
Title
FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma.
Journal
Reference
Authors
Zhang X, Gan L, Pan H, Guo S, He X, Olson ST, Mesecar A, Adam S, Unterman TG
Title
Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding.
Journal
Sequence
Reference
Authors
Anderson MJ, Viars CS, Czekay S, Cavenee WK, Arden KC
Title
Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily.
Journal
Sequence