KEGG   ORTHOLOGY: K08041Help
Entry
K08041                      KO                                     

Name
ADCY1
Definition
adenylate cyclase 1 [EC:4.6.1.1]
Pathway
Purine metabolism
Endocrine resistance
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Apelin signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Aldosterone synthesis and secretion
Relaxin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
Chagas disease (American trypanosomiasis)
Amoebiasis
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy (DCM)
Module
M00695  
cAMP signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08041  ADCY1; adenylate cyclase 1
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04371 Apelin signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04020 Calcium signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04072 Phospholipase D signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04024 cAMP signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04022 cGMP - PKG signaling pathway
    K08041  ADCY1; adenylate cyclase 1
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08041  ADCY1; adenylate cyclase 1
  Cellular community - eukaryotes
   04540 Gap junction
    K08041  ADCY1; adenylate cyclase 1
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08041  ADCY1; adenylate cyclase 1
   04062 Chemokine signaling pathway
    K08041  ADCY1; adenylate cyclase 1
  Endocrine system
   04911 Insulin secretion
    K08041  ADCY1; adenylate cyclase 1
   04923 Regulation of lipolysis in adipocyte
    K08041  ADCY1; adenylate cyclase 1
   04912 GnRH signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04913 Ovarian Steroidogenesis
    K08041  ADCY1; adenylate cyclase 1
   04915 Estrogen signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04914 Progesterone-mediated oocyte maturation
    K08041  ADCY1; adenylate cyclase 1
   04921 Oxytocin signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04926 Relaxin signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04918 Thyroid hormone synthesis
    K08041  ADCY1; adenylate cyclase 1
   04916 Melanogenesis
    K08041  ADCY1; adenylate cyclase 1
   04925 Aldosterone synthesis and secretion
    K08041  ADCY1; adenylate cyclase 1
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08041  ADCY1; adenylate cyclase 1
   04270 Vascular smooth muscle contraction
    K08041  ADCY1; adenylate cyclase 1
  Digestive system
   04970 Salivary secretion
    K08041  ADCY1; adenylate cyclase 1
   04971 Gastric acid secretion
    K08041  ADCY1; adenylate cyclase 1
   04972 Pancreatic secretion
    K08041  ADCY1; adenylate cyclase 1
   04976 Bile secretion
    K08041  ADCY1; adenylate cyclase 1
  Nervous system
   04724 Glutamatergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04727 GABAergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04725 Cholinergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04720 Long-term potentiation
    K08041  ADCY1; adenylate cyclase 1
   04723 Retrograde endocannabinoid signaling
    K08041  ADCY1; adenylate cyclase 1
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08041  ADCY1; adenylate cyclase 1
  Aging
   04211 Longevity regulating pathway - mammal
    K08041  ADCY1; adenylate cyclase 1
   04213 Longevity regulating pathway - multiple species
    K08041  ADCY1; adenylate cyclase 1
  Environmental adaptation
   04713 Circadian entrainment
    K08041  ADCY1; adenylate cyclase 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08041  ADCY1; adenylate cyclase 1
  Substance dependence
   05032 Morphine addiction
    K08041  ADCY1; adenylate cyclase 1
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08041  ADCY1; adenylate cyclase 1
  Infectious diseases
   05166 HTLV-I infection
    K08041  ADCY1; adenylate cyclase 1
   05146 Amoebiasis
    K08041  ADCY1; adenylate cyclase 1
   05142 Chagas disease (American trypanosomiasis)
    K08041  ADCY1; adenylate cyclase 1
  Drug resistance
   01522 Endocrine resistance
    K08041  ADCY1; adenylate cyclase 1
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00695  cAMP signaling
     K08041  ADCY1; adenylate cyclase 1
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08041  ADCY1; adenylate cyclase 1
BRITE hierarchy
Other DBs
Genes
HSA: 
107(ADCY1)
PTR: 
PPS: 
100984585(ADCY1)
GGO: 
101125943(ADCY1)
PON: 
100449504(ADCY1)
NLE: 
100595636(ADCY1)
MCC: 
697230(ADCY1)
MCF: 
102147015(ADCY1)
CSAB: 
103226115(ADCY1)
RRO: 
104671165(ADCY1)
RBB: 
108534793(ADCY1)
CJC: 
100394265(ADCY1)
SBQ: 
101027981(ADCY1)
MMU: 
432530(Adcy1)
RNO: 
305509(Adcy1)
CGE: 
100764561(Adcy1)
NGI: 
103741433(Adcy1)
HGL: 
101711366(Adcy1)
CCAN: 
109694874(Adcy1)
OCU: 
TUP: 
102468873(ADCY1)
CFA: 
607357(ADCY1)
AML: 
100472777(ADCY1)
UMR: 
FCA: 
101101375(ADCY1)
PTG: 
102961712(ADCY1)
AJU: 
106968223(ADCY1)
BTA: 
281601(ADCY1)
BOM: 
102267116(ADCY1)
BIU: 
109557525(ADCY1)
PHD: 
102335300(ADCY1)
CHX: 
102180724(ADCY1)
OAS: 
101117327(ADCY1)
SSC: 
100624934(ADCY1)
CFR: 
102517882(ADCY1)
CDK: 
105095715(ADCY1)
BACU: 
102998650(ADCY1)
LVE: 
103081539(ADCY1)
ECB: 
100065563(ADCY1)
EPZ: 
103550430(ADCY1)
EAI: 
106822932(ADCY1)
MYB: 
102257679(ADCY1)
MYD: 
102759978(ADCY1)
HAI: 
109373011(ADCY1)
RSS: 
109447331(ADCY1)
PALE: 
102887497(ADCY1)
LAV: 
100671072(ADCY1)
MDO: 
100030463(ADCY1)
SHR: 
100922193(ADCY1)
OAA: 
GGA: 
420788(ADCY1)
CJO: 
107309766(ADCY1)
APLA: 
101804073(ADCY1)
ACYG: 
106046455(ADCY1)
TGU: 
100226080(ADCY1)
GFR: 
102040399(ADCY1)
FAB: 
101807752(ADCY1)
PHI: 
102110269(ADCY1)
PMAJ: 
107201036(ADCY1)
CCW: 
104689252(ADCY1)
FPG: 
101914769(ADCY1)
FCH: 
102056699(ADCY1)
CLV: 
102094612(ADCY1)
AAM: 
106492856(ADCY1)
ASN: 
102372645(ADCY1)
AMJ: 
102573818(ADCY1)
PSS: 
102445759(ADCY1)
CMY: 
102939135(ADCY1)
CPIC: 
101935286(ADCY1)
ACS: 
100564004(adcy1)
PVT: 
110091617(ADCY1)
PBI: 
GJA: 
107119176(ADCY1)
XLA: 
108695214 108705348(adcy1.S) 108718988(adcy1.L)
XTR: 
100492373(adcy1)
NPR: 
108796974(ADCY1)
DRE: 
557026(adcy1a) 569499(adcy1b)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102351204(ADCY1)
CMK: 
103187011(adcy1)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
TCA: 
661438(rut)
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
DPX: 
ISC: 
TUT: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
PIF: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9662407
  Authors
Abdel-Majid RM, Leong WL, Schalkwyk LC, Smallman DS, Wong ST, Storm DR, Fine A, Dobson MJ, Guernsey DL, Neumann PE
  Title
Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex.
  Journal
Nat Genet 19:289-91 (1998)
DOI:10.1038/980
  Sequence
[mmu:432530]

KEGG   ORTHOLOGY: K08042Help
Entry
K08042                      KO                                     

Name
ADCY2
Definition
adenylate cyclase 2 [EC:4.6.1.1]
Pathway
Purine metabolism
Endocrine resistance
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Apelin signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Glucagon signaling pathway
Regulation of lipolysis in adipocytes
Aldosterone synthesis and secretion
Relaxin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy (DCM)
Module
M00695  
cAMP signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08042  ADCY2; adenylate cyclase 2
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04371 Apelin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04020 Calcium signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04072 Phospholipase D signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04024 cAMP signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04022 cGMP - PKG signaling pathway
    K08042  ADCY2; adenylate cyclase 2
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08042  ADCY2; adenylate cyclase 2
  Cellular community - eukaryotes
   04540 Gap junction
    K08042  ADCY2; adenylate cyclase 2
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08042  ADCY2; adenylate cyclase 2
   04062 Chemokine signaling pathway
    K08042  ADCY2; adenylate cyclase 2
  Endocrine system
   04911 Insulin secretion
    K08042  ADCY2; adenylate cyclase 2
   04922 Glucagon signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04923 Regulation of lipolysis in adipocyte
    K08042  ADCY2; adenylate cyclase 2
   04912 GnRH signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04913 Ovarian Steroidogenesis
    K08042  ADCY2; adenylate cyclase 2
   04915 Estrogen signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04914 Progesterone-mediated oocyte maturation
    K08042  ADCY2; adenylate cyclase 2
   04921 Oxytocin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04926 Relaxin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04918 Thyroid hormone synthesis
    K08042  ADCY2; adenylate cyclase 2
   04916 Melanogenesis
    K08042  ADCY2; adenylate cyclase 2
   04925 Aldosterone synthesis and secretion
    K08042  ADCY2; adenylate cyclase 2
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08042  ADCY2; adenylate cyclase 2
   04270 Vascular smooth muscle contraction
    K08042  ADCY2; adenylate cyclase 2
  Digestive system
   04970 Salivary secretion
    K08042  ADCY2; adenylate cyclase 2
   04971 Gastric acid secretion
    K08042  ADCY2; adenylate cyclase 2
   04972 Pancreatic secretion
    K08042  ADCY2; adenylate cyclase 2
   04976 Bile secretion
    K08042  ADCY2; adenylate cyclase 2
  Nervous system
   04724 Glutamatergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04727 GABAergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04725 Cholinergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04723 Retrograde endocannabinoid signaling
    K08042  ADCY2; adenylate cyclase 2
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08042  ADCY2; adenylate cyclase 2
  Aging
   04211 Longevity regulating pathway - mammal
    K08042  ADCY2; adenylate cyclase 2
   04213 Longevity regulating pathway - multiple species
    K08042  ADCY2; adenylate cyclase 2
  Environmental adaptation
   04713 Circadian entrainment
    K08042  ADCY2; adenylate cyclase 2
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08042  ADCY2; adenylate cyclase 2
  Substance dependence
   05032 Morphine addiction
    K08042  ADCY2; adenylate cyclase 2
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08042  ADCY2; adenylate cyclase 2
  Infectious diseases
   05166 HTLV-I infection
    K08042  ADCY2; adenylate cyclase 2
  Drug resistance
   01522 Endocrine resistance
    K08042  ADCY2; adenylate cyclase 2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00695  cAMP signaling
     K08042  ADCY2; adenylate cyclase 2
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08042  ADCY2; adenylate cyclase 2
BRITE hierarchy
Other DBs
Genes
HSA: 
108(ADCY2)
PTR: 
100608010(ADCY2)
PPS: 
100992014(ADCY2)
GGO: 
101141389(ADCY2)
PON: 
NLE: 
100600367(ADCY2)
MCC: 
695328(ADCY2)
MCF: 
102130114(ADCY2)
CSAB: 
103214981(ADCY2)
RRO: 
104674083(ADCY2)
RBB: 
108536960(ADCY2)
CJC: 
100385658(ADCY2)
SBQ: 
101043334(ADCY2)
MMU: 
210044(Adcy2)
RNO: 
81636(Adcy2)
CGE: 
100773811(Adcy2)
NGI: 
103735350(Adcy2)
HGL: 
101718304(Adcy2)
CCAN: 
OCU: 
100009201(ADCY2)
TUP: 
102492353(ADCY2)
CFA: 
478624(ADCY2)
AML: 
100473195(ADCY2)
UMR: 
103679250(ADCY2)
FCA: 
101094327(ADCY2)
PTG: 
102949732(ADCY2)
AJU: 
106971248(ADCY2)
BTA: 
510708(ADCY2)
BOM: 
102274117(ADCY2)
BIU: 
109574822(ADCY2)
PHD: 
102326467(ADCY2)
CHX: 
102171922(ADCY2)
OAS: 
101102089(ADCY2)
SSC: 
100517503(ADCY2)
CFR: 
102510993(ADCY2)
CDK: 
105094039(ADCY2)
BACU: 
103020085(ADCY2)
LVE: 
103084817(ADCY2)
ECB: 
100071337(ADCY2)
EPZ: 
EAI: 
106823001(ADCY2)
MYB: 
102260356(ADCY2)
MYD: 
102774384(ADCY2)
HAI: 
109375976(ADCY2)
RSS: 
109453572(ADCY2)
PALE: 
102893265(ADCY2)
LAV: 
100673570(ADCY2)
MDO: 
100013164(ADCY2)
SHR: 
100922434(ADCY2)
OAA: 
100089708(ADCY2)
GGA: 
420935(ADCY2)
MGP: 
100540738(ADCY2)
CJO: 
107309543(ADCY2)
APLA: 
101803512(ADCY2)
ACYG: 
106036531(ADCY2)
TGU: 
100223820(ADCY2)
GFR: 
102038853(ADCY2)
FAB: 
101808400(ADCY2)
PHI: 
102113898(ADCY2)
PMAJ: 
107199935(ADCY2)
CCW: 
104685925(ADCY2)
FPG: 
101911647(ADCY2)
FCH: 
102049688(ADCY2)
CLV: 
102097532(ADCY2)
AAM: 
106492356(ADCY2)
ASN: 
102383838(ADCY2)
AMJ: 
102562034(ADCY2)
PSS: 
102444057(ADCY2)
CMY: 
102930552(ADCY2)
CPIC: 
101952054(ADCY2)
ACS: 
PVT: 
PBI: 
103050340(ADCY2)
GJA: 
107108835(ADCY2)
DRE: 
557902(adcy2b) 563724(adcy2a)
SRX: 
SANH: 
SGH: 
IPU: 
108272199(Adcy2) 108272792(ADCY2)
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
105012408(adcy2)
SFM: 
LCM: 
CMK: 
103183192(adcy2)
BFO: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD14841(Dsim_GD14841)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
TUT: 
LGI: 
CRG: 
LAK: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1427768
  Authors
Stengel D, Parma J, Gannage MH, Roeckel N, Mattei MG, Barouki R, Hanoune J
  Title
Different chromosomal localization of two adenylyl cyclase genes expressed in human brain.
  Journal
Hum Genet 90:126-30 (1992)
DOI:10.1007/BF00210755
  Sequence
[hsa:108]
Reference
  Authors
Hardin M, Zielinski J, Wan ES, Hersh CP, Castaldi PJ, Schwinder E, Hawrylkiewicz I, Sliwinski P, Cho MH, Silverman EK
  Title
CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland.
  Journal
Am J Respir Cell Mol Biol 47:203-8 (2012)
DOI:10.1165/rcmb.2012-0011OC

KEGG   ORTHOLOGY: K08043Help
Entry
K08043                      KO                                     

Name
ADCY3
Definition
adenylate cyclase 3 [EC:4.6.1.1]
Pathway
Purine metabolism
Endocrine resistance
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Apelin signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Olfactory transduction
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Aldosterone synthesis and secretion
Relaxin signaling pathway
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
Vibrio cholerae infection
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy (DCM)
Module
M00695  
cAMP signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08043  ADCY3; adenylate cyclase 3
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04371 Apelin signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04020 Calcium signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04072 Phospholipase D signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04024 cAMP signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04022 cGMP - PKG signaling pathway
    K08043  ADCY3; adenylate cyclase 3
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08043  ADCY3; adenylate cyclase 3
  Cellular community - eukaryotes
   04540 Gap junction
    K08043  ADCY3; adenylate cyclase 3
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08043  ADCY3; adenylate cyclase 3
   04062 Chemokine signaling pathway
    K08043  ADCY3; adenylate cyclase 3
  Endocrine system
   04911 Insulin secretion
    K08043  ADCY3; adenylate cyclase 3
   04923 Regulation of lipolysis in adipocyte
    K08043  ADCY3; adenylate cyclase 3
   04912 GnRH signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04913 Ovarian Steroidogenesis
    K08043  ADCY3; adenylate cyclase 3
   04915 Estrogen signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04914 Progesterone-mediated oocyte maturation
    K08043  ADCY3; adenylate cyclase 3
   04921 Oxytocin signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04926 Relaxin signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04918 Thyroid hormone synthesis
    K08043  ADCY3; adenylate cyclase 3
   04916 Melanogenesis
    K08043  ADCY3; adenylate cyclase 3
   04925 Aldosterone synthesis and secretion
    K08043  ADCY3; adenylate cyclase 3
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08043  ADCY3; adenylate cyclase 3
   04270 Vascular smooth muscle contraction
    K08043  ADCY3; adenylate cyclase 3
  Digestive system
   04970 Salivary secretion
    K08043  ADCY3; adenylate cyclase 3
   04971 Gastric acid secretion
    K08043  ADCY3; adenylate cyclase 3
   04972 Pancreatic secretion
    K08043  ADCY3; adenylate cyclase 3
   04976 Bile secretion
    K08043  ADCY3; adenylate cyclase 3
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    K08043  ADCY3; adenylate cyclase 3
  Nervous system
   04724 Glutamatergic synapse
    K08043  ADCY3; adenylate cyclase 3
   04727 GABAergic synapse
    K08043  ADCY3; adenylate cyclase 3
   04725 Cholinergic synapse
    K08043  ADCY3; adenylate cyclase 3
   04723 Retrograde endocannabinoid signaling
    K08043  ADCY3; adenylate cyclase 3
  Sensory system
   04740 Olfactory transduction
    K08043  ADCY3; adenylate cyclase 3
   04750 Inflammatory mediator regulation of TRP channels
    K08043  ADCY3; adenylate cyclase 3
  Aging
   04211 Longevity regulating pathway - mammal
    K08043  ADCY3; adenylate cyclase 3
   04213 Longevity regulating pathway - multiple species
    K08043  ADCY3; adenylate cyclase 3
  Environmental adaptation
   04713 Circadian entrainment
    K08043  ADCY3; adenylate cyclase 3
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08043  ADCY3; adenylate cyclase 3
  Substance dependence
   05032 Morphine addiction
    K08043  ADCY3; adenylate cyclase 3
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08043  ADCY3; adenylate cyclase 3
  Infectious diseases
   05110 Vibrio cholerae infection
    K08043  ADCY3; adenylate cyclase 3
   05166 HTLV-I infection
    K08043  ADCY3; adenylate cyclase 3
  Drug resistance
   01522 Endocrine resistance
    K08043  ADCY3; adenylate cyclase 3
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00695  cAMP signaling
     K08043  ADCY3; adenylate cyclase 3
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08043  ADCY3; adenylate cyclase 3
BRITE hierarchy
Other DBs
Genes
HSA: 
109(ADCY3)
PTR: 
459070(ADCY3)
PPS: 
100995134(ADCY3)
GGO: 
101144031(ADCY3)
PON: 
100431221(ADCY3)
NLE: 
100586735(ADCY3)
MCC: 
693523(ADCY3)
MCF: 
101925741(ADCY3)
CSAB: 
103220665(ADCY3)
RRO: 
104658457(ADCY3)
RBB: 
108543021(ADCY3)
CJC: 
100415165(ADCY3)
SBQ: 
101040601(ADCY3)
MMU: 
104111(Adcy3)
RNO: 
64508(Adcy3)
CGE: 
100770498(Adcy3)
NGI: 
103746460(Adcy3)
HGL: 
101713887(Adcy3)
CCAN: 
109685686(Adcy3)
OCU: 
100343958(ADCY3)
TUP: 
102477532(ADCY3)
CFA: 
482994(ADCY3)
AML: 
100471164(ADCY3)
UMR: 
103671685(ADCY3)
FCA: 
101088157(ADCY3)
PTG: 
102952000(ADCY3)
AJU: 
BTA: 
535603(ADCY3)
BOM: 
102282732(ADCY3)
BIU: 
109566330(ADCY3)
PHD: 
102326984(ADCY3)
CHX: 
102169019(ADCY3)
OAS: 
101108203(ADCY3)
SSC: 
100514402(ADCY3)
CFR: 
102512950(ADCY3)
CDK: 
105100030(ADCY3)
BACU: 
103020845(ADCY3)
LVE: 
103076182(ADCY3)
ECB: 
100055961(ADCY3)
EPZ: 
103547823(ADCY3)
EAI: 
106841140(ADCY3)
MYB: 
102261014(ADCY3)
MYD: 
102757252(ADCY3)
HAI: 
109385186(ADCY3)
RSS: 
109435127(ADCY3)
PALE: 
102886232(ADCY3)
LAV: 
100674724(ADCY3)
MDO: 
100025332(ADCY3)
SHR: 
100925657(ADCY3)
OAA: 
100085901(ADCY3)
GGA: 
422013(ADCY3)
MGP: 
100538467(ADCY3)
CJO: 
107312346(ADCY3)
APLA: 
101791112(ADCY3)
ACYG: 
106038094(ADCY3)
FAB: 
PHI: 
102112216(ADCY3)
FPG: 
101921567(ADCY3)
FCH: 
102047195(ADCY3)
CLV: 
102092425(ADCY3)
AAM: 
106488018(ADCY3)
ASN: 
102374249(ADCY3)
AMJ: 
102566746(ADCY3)
PSS: 
102463305(ADCY3)
CMY: 
102941584(ADCY3)
CPIC: 
101948171(ADCY3)
ACS: 
100558229(adcy3)
PVT: 
110089954(ADCY3)
PBI: 
GJA: 
107124706(ADCY3)
XLA: 
XTR: 
100038110(dnajc27)
NPR: 
108795542(ADCY3)
DRE: 
571825(adcy3a)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
108929094(adcy3)
LCM: 
BFO: 
SPU: 
SKO: 
100372163(ADCY3)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD24328(Dsim_GD24328) Dsimw501_GD29214(Dsim_GD29214)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
AaeL_AAEL009344(AAEL801139)
CQU: 
AME: 
408363(Ac3)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
DPX: 
TUT: 
LGI: 
CRG: 
LAK: 
NVE: 
ADF: 
TAD: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2255909
  Authors
Bakalyar HA, Reed RR
  Title
Identification of a specialized adenylyl cyclase that may mediate odorant detection.
  Journal
Science 250:1403-6 (1990)
DOI:10.1126/science.2255909
  Sequence
[rno:64508]

KEGG   ORTHOLOGY: K08044Help
Entry
K08044                      KO                                     

Name
ADCY4
Definition
adenylate cyclase 4 [EC:4.6.1.1]
Pathway
Purine metabolism
Endocrine resistance
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Apelin signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Aldosterone synthesis and secretion
Relaxin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy (DCM)
Module
M00695  
cAMP signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08044  ADCY4; adenylate cyclase 4
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04371 Apelin signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04020 Calcium signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04072 Phospholipase D signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04024 cAMP signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04022 cGMP - PKG signaling pathway
    K08044  ADCY4; adenylate cyclase 4
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08044  ADCY4; adenylate cyclase 4
  Cellular community - eukaryotes
   04540 Gap junction
    K08044  ADCY4; adenylate cyclase 4
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08044  ADCY4; adenylate cyclase 4
   04062 Chemokine signaling pathway
    K08044  ADCY4; adenylate cyclase 4
  Endocrine system
   04911 Insulin secretion
    K08044  ADCY4; adenylate cyclase 4
   04923 Regulation of lipolysis in adipocyte
    K08044  ADCY4; adenylate cyclase 4
   04912 GnRH signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04913 Ovarian Steroidogenesis
    K08044  ADCY4; adenylate cyclase 4
   04915 Estrogen signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04914 Progesterone-mediated oocyte maturation
    K08044  ADCY4; adenylate cyclase 4
   04921 Oxytocin signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04926 Relaxin signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04918 Thyroid hormone synthesis
    K08044  ADCY4; adenylate cyclase 4
   04916 Melanogenesis
    K08044  ADCY4; adenylate cyclase 4
   04925 Aldosterone synthesis and secretion
    K08044  ADCY4; adenylate cyclase 4
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08044  ADCY4; adenylate cyclase 4
   04270 Vascular smooth muscle contraction
    K08044  ADCY4; adenylate cyclase 4
  Digestive system
   04970 Salivary secretion
    K08044  ADCY4; adenylate cyclase 4
   04971 Gastric acid secretion
    K08044  ADCY4; adenylate cyclase 4
   04972 Pancreatic secretion
    K08044  ADCY4; adenylate cyclase 4
   04976 Bile secretion
    K08044  ADCY4; adenylate cyclase 4
  Nervous system
   04724 Glutamatergic synapse
    K08044  ADCY4; adenylate cyclase 4
   04727 GABAergic synapse
    K08044  ADCY4; adenylate cyclase 4
   04725 Cholinergic synapse
    K08044  ADCY4; adenylate cyclase 4
   04723 Retrograde endocannabinoid signaling
    K08044  ADCY4; adenylate cyclase 4
  Sensory system
   04742 Taste transduction
    K08044  ADCY4; adenylate cyclase 4
   04750 Inflammatory mediator regulation of TRP channels
    K08044  ADCY4; adenylate cyclase 4
  Aging
   04211 Longevity regulating pathway - mammal
    K08044  ADCY4; adenylate cyclase 4
   04213 Longevity regulating pathway - multiple species
    K08044  ADCY4; adenylate cyclase 4
  Environmental adaptation
   04713 Circadian entrainment
    K08044  ADCY4; adenylate cyclase 4
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08044  ADCY4; adenylate cyclase 4
  Substance dependence
   05032 Morphine addiction
    K08044  ADCY4; adenylate cyclase 4
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08044  ADCY4; adenylate cyclase 4
  Infectious diseases
   05166 HTLV-I infection
    K08044  ADCY4; adenylate cyclase 4
  Drug resistance
   01522 Endocrine resistance
    K08044  ADCY4; adenylate cyclase 4
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00695  cAMP signaling
     K08044  ADCY4; adenylate cyclase 4
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08044  ADCY4; adenylate cyclase 4
BRITE hierarchy
Other DBs
Genes
HSA: 
196883(ADCY4)
PTR: 
452819(ADCY4)
PPS: 
100978200(ADCY4)
GGO: 
101125890(ADCY4)
PON: 
100460806(ADCY4)
NLE: 
100603282(ADCY4)
MCC: 
714684(ADCY4)
MCF: 
102123837(ADCY4)
CSAB: 
103228726(ADCY4)
RRO: 
104662674(ADCY4)
RBB: 
108540946(ADCY4)
CJC: 
100415141(ADCY4)
SBQ: 
101044688(ADCY4)
MMU: 
104110(Adcy4)
RNO: 
54223(Adcy4)
CGE: 
100768998(Adcy4)
NGI: 
103739411(Adcy4)
HGL: 
101719464(Adcy4)
CCAN: 
109685852(Adcy4)
OCU: 
100346742(ADCY4)
TUP: 
102490273(ADCY4)
CFA: 
480271(ADCY4)
AML: 
100471940(ADCY4)
UMR: 
103679331(ADCY4)
FCA: 
101097735(ADCY4)
PTG: 
102965866(ADCY4)
AJU: 
106987869(ADCY4)
BTA: 
788151(ADCY4)
BOM: 
102286168(ADCY4)
BIU: 
109564199(ADCY4)
PHD: 
102337499(ADCY4)
CHX: 
102185469(ADCY4)
OAS: 
101119139(ADCY4)
SSC: 
100152067(ADCY4)
CFR: 
102524031(ADCY4)
CDK: 
105102432(ADCY4)
BACU: 
103005549(ADCY4)
LVE: 
103075499(ADCY4)
ECB: 
100054305(ADCY4)
EPZ: 
103561050(ADCY4)
EAI: 
106848607(ADCY4)
MYB: 
102247996(ADCY4)
MYD: 
102762536(ADCY4)
HAI: 
109393593(ADCY4)
RSS: 
109436107(ADCY4)
PALE: 
102890575(ADCY4)
LAV: 
100675525(ADCY4)
MDO: 
100030872(ADCY4)
SHR: 
100920243(ADCY4)
ASN: 
102385636(ADCY4)
AMJ: 
102558956(ADCY4)
PSS: 
102451515(ADCY4)
CMY: 
102946725(ADCY4)
CPIC: 
101936524(ADCY4)
ACS: 
100562762(adcy4)
PVT: 
110091692(ADCY4)
PBI: 
103055695(ADCY4)
GJA: 
107111738(ADCY4)
XLA: 
XTR: 
100497212(adcy4)
NPR: 
108788450(ADCY4)
SRX: 
SANH: 
SGH: 
IPU: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
OVI: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ludwig MG, Seuwen K
  Title
Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.
  Journal
J Recept Signal Transduct Res 22:79-110 (2002)
DOI:10.1081/RRS-120014589
  Sequence
[hsa:196883]

KEGG   ORTHOLOGY: K08045Help
Entry
K08045                      KO                                     

Name
ADCY5
Definition
adenylate cyclase 5 [EC:4.6.1.1]
Pathway
Purine metabolism
Endocrine resistance
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Apelin signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Renin secretion
Aldosterone synthesis and secretion
Relaxin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Morphine addiction
Alcoholism
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy (DCM)
Module
M00695  
cAMP signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08045  ADCY5; adenylate cyclase 5
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08045  ADCY5; adenylate cyclase 5
   04371 Apelin signaling pathway
    K08045  ADCY5; adenylate cyclase 5
   04072 Phospholipase D signaling pathway
    K08045  ADCY5; adenylate cyclase 5
   04024 cAMP signaling pathway
    K08045  ADCY5; adenylate cyclase 5
   04022 cGMP - PKG signaling pathway
    K08045  ADCY5; adenylate cyclase 5
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08045  ADCY5; adenylate cyclase 5
  Cellular community - eukaryotes
   04540 Gap junction
    K08045  ADCY5; adenylate cyclase 5
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08045  ADCY5; adenylate cyclase 5
   04062 Chemokine signaling pathway
    K08045  ADCY5; adenylate cyclase 5
  Endocrine system
   04911 Insulin secretion
    K08045  ADCY5; adenylate cyclase 5
   04923 Regulation of lipolysis in adipocyte
    K08045  ADCY5; adenylate cyclase 5
   04912 GnRH signaling pathway
    K08045  ADCY5; adenylate cyclase 5
   04913 Ovarian Steroidogenesis
    K08045  ADCY5; adenylate cyclase 5
   04915 Estrogen signaling pathway
    K08045  ADCY5; adenylate cyclase 5
   04914 Progesterone-mediated oocyte maturation
    K08045  ADCY5; adenylate cyclase 5
   04921 Oxytocin signaling pathway
    K08045  ADCY5; adenylate cyclase 5
   04926 Relaxin signaling pathway
    K08045  ADCY5; adenylate cyclase 5
   04918 Thyroid hormone synthesis
    K08045  ADCY5; adenylate cyclase 5
   04916 Melanogenesis
    K08045  ADCY5; adenylate cyclase 5
   04924 Renin secretion
    K08045  ADCY5; adenylate cyclase 5
   04925 Aldosterone synthesis and secretion
    K08045  ADCY5; adenylate cyclase 5
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08045  ADCY5; adenylate cyclase 5
   04270 Vascular smooth muscle contraction
    K08045  ADCY5; adenylate cyclase 5
  Digestive system
   04970 Salivary secretion
    K08045  ADCY5; adenylate cyclase 5
   04971 Gastric acid secretion
    K08045  ADCY5; adenylate cyclase 5
   04972 Pancreatic secretion
    K08045  ADCY5; adenylate cyclase 5
   04976 Bile secretion
    K08045  ADCY5; adenylate cyclase 5
  Nervous system
   04724 Glutamatergic synapse
    K08045  ADCY5; adenylate cyclase 5
   04727 GABAergic synapse
    K08045  ADCY5; adenylate cyclase 5
   04725 Cholinergic synapse
    K08045  ADCY5; adenylate cyclase 5
   04728 Dopaminergic synapse
    K08045  ADCY5; adenylate cyclase 5
   04726 Serotonergic synapse
    K08045  ADCY5; adenylate cyclase 5
   04723 Retrograde endocannabinoid signaling
    K08045  ADCY5; adenylate cyclase 5
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08045  ADCY5; adenylate cyclase 5
  Aging
   04211 Longevity regulating pathway - mammal
    K08045  ADCY5; adenylate cyclase 5
   04213 Longevity regulating pathway - multiple species
    K08045  ADCY5; adenylate cyclase 5
  Environmental adaptation
   04713 Circadian entrainment
    K08045  ADCY5; adenylate cyclase 5
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08045  ADCY5; adenylate cyclase 5
  Neurodegenerative diseases
   05012 Parkinson's disease
    K08045  ADCY5; adenylate cyclase 5
  Substance dependence
   05030 Cocaine addiction
    K08045  ADCY5; adenylate cyclase 5
   05031 Amphetamine addiction
    K08045  ADCY5; adenylate cyclase 5
   05032 Morphine addiction
    K08045  ADCY5; adenylate cyclase 5
   05034 Alcoholism
    K08045  ADCY5; adenylate cyclase 5
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08045  ADCY5; adenylate cyclase 5
  Infectious diseases
   05166 HTLV-I infection
    K08045  ADCY5; adenylate cyclase 5
  Drug resistance
   01522 Endocrine resistance
    K08045  ADCY5; adenylate cyclase 5
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00695  cAMP signaling
     K08045  ADCY5; adenylate cyclase 5
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08045  ADCY5; adenylate cyclase 5
BRITE hierarchy
Other DBs
Genes
HSA: 
111(ADCY5)
PTR: 
470905(ADCY5)
PPS: 
100989177(ADCY5)
GGO: 
101150181(ADCY5)
PON: 
100454138(ADCY5)
NLE: 
100580455(ADCY5)
MCC: 
715897(ADCY5)
MCF: 
102135142(ADCY5)
CSAB: 
103228169(ADCY5)
RRO: 
RBB: 
108517430(ADCY5)
CJC: 
100412782(ADCY5)
SBQ: 
101049747(ADCY5)
MMU: 
224129(Adcy5)
RNO: 
64532(Adcy5)
CGE: 
100765958(Adcy5)
NGI: 
103741989(Adcy5)
HGL: 
101702436(Adcy5)
CCAN: 
109701078(Adcy5)
OCU: 
100009315(ADCY5)
TUP: 
102490639(ADCY5)
CFA: 
403859(ADCY5)
AML: 
100482519(ADCY5)
UMR: 
103678826(ADCY5)
FCA: 
101100749(ADCY5)
PTG: 
102969833(ADCY5)
AJU: 
106984082(ADCY5)
BTA: 
505740(ADCY5)
BOM: 
102276460(ADCY5)
BIU: 
109555842(ADCY5)
PHD: 
102343137(ADCY5)
CHX: 
102189798(ADCY5)
OAS: 
SSC: 
100155970(ADCY5)
CFR: 
102503785(ADCY5)
CDK: 
105090284(ADCY5)
BACU: 
103006764(ADCY5)
LVE: 
103091169(ADCY5)
ECB: 
100070498(ADCY5)
EPZ: 
103563830(ADCY5)
EAI: 
106823728(ADCY5)
MYB: 
102257731(ADCY5)
MYD: 
102760678(ADCY5)
HAI: 
109387200(ADCY5)
RSS: 
109451056(ADCY5)
PALE: 
102897495(ADCY5)
LAV: 
100670244(ADCY5)
MDO: 
100019274(ADCY5)
SHR: 
100929558(ADCY5)
GGA: 
395340(ADCY5)
MGP: 
100547372(ADCY5)
CJO: 
107316827(ADCY5)
APLA: 
ACYG: 
106029894(ADCY5)
TGU: 
100220777(ADCY5)
GFR: 
102031760(ADCY5)
FAB: 
101807084(ADCY5)
PHI: 
102107286(ADCY5)
PMAJ: 
107207500(ADCY5)
CCW: 
104694019(ADCY5)
FPG: 
101922323(ADCY5)
FCH: 
102049855(ADCY5)
CLV: 
102085466(ADCY5)
AAM: 
106499045(ADCY5)
ASN: 
AMJ: 
102562224(ADCY5)
PSS: 
102461993(ADCY5)
CMY: 
102937309(ADCY5)
CPIC: 
101950146(ADCY5)
ACS: 
100558125(adcy5)
PVT: 
110083012(ADCY5)
PBI: 
103060584(ADCY5)
GJA: 
XLA: 
XTR: 
NPR: 
DRE: 
562619(adcy5)
SRX: 
SANH: 
SGH: 
IPU: 
108266230(adcy5)
TRU: 
101070040(adcy5)
TNG: 
LCO: 
104918228(adcy5)
NCC: 
MZE: 
101480556(adcy5)
OLA: 
101174709(adcy5)
XMA: 
CSEM: 
103391879(adcy5)
LCF: 
108897108(adcy5)
HCQ: 
BPEC: 
110156638(adcy5)
SASA: 
ELS: 
105016121(adcy5)
SFM: 
LCM: 
102353581(ADCY5)
CMK: 
BFO: 
CIN: 
778532(rut)
SPU: 
SKO: 
DPE: 
AME: 
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
TCA: 
DPA: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
DPX: 
ISC: 
LOA: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
ADF: 
TAD: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ludwig MG, Seuwen K
  Title
Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.
  Journal
J Recept Signal Transduct Res 22:79-110 (2002)
DOI:10.1081/RRS-120014589
  Sequence
[hsa:111]
Reference
  Authors
Ding Q, Gros R, Gray ID, Taussig R, Ferguson SS, Feldman RD
  Title
Raf kinase activation of adenylyl cyclases: isoform-selective regulation.
  Journal
Mol Pharmacol 66:921-8 (2004)
DOI:10.1124/mol.66.4.921

KEGG   ORTHOLOGY: K08046Help
Entry
K08046                      KO                                     

Name
ADCY6
Definition
adenylate cyclase 6 [EC:4.6.1.1]
Pathway
Purine metabolism
Endocrine resistance
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Apelin signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Renin secretion
Aldosterone synthesis and secretion
Relaxin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy (DCM)
Module
M00695  
cAMP signaling
Disease
H00865  
Lethal congenital contractural syndrome (LCCS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08046  ADCY6; adenylate cyclase 6
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04371 Apelin signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04072 Phospholipase D signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04024 cAMP signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04022 cGMP - PKG signaling pathway
    K08046  ADCY6; adenylate cyclase 6
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08046  ADCY6; adenylate cyclase 6
  Cellular community - eukaryotes
   04540 Gap junction
    K08046  ADCY6; adenylate cyclase 6
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08046  ADCY6; adenylate cyclase 6
   04062 Chemokine signaling pathway
    K08046  ADCY6; adenylate cyclase 6
  Endocrine system
   04911 Insulin secretion
    K08046  ADCY6; adenylate cyclase 6
   04923 Regulation of lipolysis in adipocyte
    K08046  ADCY6; adenylate cyclase 6
   04912 GnRH signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04913 Ovarian Steroidogenesis
    K08046  ADCY6; adenylate cyclase 6
   04915 Estrogen signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04914 Progesterone-mediated oocyte maturation
    K08046  ADCY6; adenylate cyclase 6
   04921 Oxytocin signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04926 Relaxin signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04918 Thyroid hormone synthesis
    K08046  ADCY6; adenylate cyclase 6
   04916 Melanogenesis
    K08046  ADCY6; adenylate cyclase 6
   04924 Renin secretion
    K08046  ADCY6; adenylate cyclase 6
   04925 Aldosterone synthesis and secretion
    K08046  ADCY6; adenylate cyclase 6
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08046  ADCY6; adenylate cyclase 6
   04270 Vascular smooth muscle contraction
    K08046  ADCY6; adenylate cyclase 6
  Digestive system
   04970 Salivary secretion
    K08046  ADCY6; adenylate cyclase 6
   04971 Gastric acid secretion
    K08046  ADCY6; adenylate cyclase 6
   04972 Pancreatic secretion
    K08046  ADCY6; adenylate cyclase 6
   04976 Bile secretion
    K08046  ADCY6; adenylate cyclase 6
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    K08046  ADCY6; adenylate cyclase 6
   04961 Endocrine and other factor-regulated calcium reabsorption
    K08046  ADCY6; adenylate cyclase 6
  Nervous system
   04724 Glutamatergic synapse
    K08046  ADCY6; adenylate cyclase 6
   04727 GABAergic synapse
    K08046  ADCY6; adenylate cyclase 6
   04725 Cholinergic synapse
    K08046  ADCY6; adenylate cyclase 6
   04723 Retrograde endocannabinoid signaling
    K08046  ADCY6; adenylate cyclase 6
  Sensory system
   04742 Taste transduction
    K08046  ADCY6; adenylate cyclase 6
   04750 Inflammatory mediator regulation of TRP channels
    K08046  ADCY6; adenylate cyclase 6
  Aging
   04211 Longevity regulating pathway - mammal
    K08046  ADCY6; adenylate cyclase 6
   04213 Longevity regulating pathway - multiple species
    K08046  ADCY6; adenylate cyclase 6
  Environmental adaptation
   04713 Circadian entrainment
    K08046  ADCY6; adenylate cyclase 6
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08046  ADCY6; adenylate cyclase 6
  Substance dependence
   05032 Morphine addiction
    K08046  ADCY6; adenylate cyclase 6
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08046  ADCY6; adenylate cyclase 6
  Infectious diseases
   05166 HTLV-I infection
    K08046  ADCY6; adenylate cyclase 6
  Drug resistance
   01522 Endocrine resistance
    K08046  ADCY6; adenylate cyclase 6
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00695  cAMP signaling
     K08046  ADCY6; adenylate cyclase 6
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08046  ADCY6; adenylate cyclase 6
BRITE hierarchy
Other DBs
Genes
HSA: 
112(ADCY6)
PTR: 
451866(ADCY6)
PPS: 
100991116(ADCY6)
GGO: 
101139873(ADCY6)
PON: 
100438178(ADCY6)
NLE: 
100589304(ADCY6)
MCC: 
707978(ADCY6)
MCF: 
102116122(ADCY6)
CSAB: 
103238242(ADCY6)
RRO: 
RBB: 
108543933(ADCY6)
CJC: 
100406617(ADCY6)
SBQ: 
101037803(ADCY6)
MMU: 
11512(Adcy6)
RNO: 
25289(Adcy6)
CGE: 
100768368(Adcy6)
NGI: 
103750558(Adcy6)
HGL: 
101698189(Adcy6)
CCAN: 
109686365(Adcy6)
OCU: 
100354934(ADCY6)
TUP: 
102468478(ADCY6)
CFA: 
477625(ADCY6)
AML: 
100476922(ADCY6)
UMR: 
103675618(ADCY6)
FCA: 
101091211(ADCY6)
PTG: 
102949044(ADCY6)
AJU: 
106969297(ADCY6)
BTA: 
509936(ADCY6)
BOM: 
102265325(ADCY6)
BIU: 
109559159(ADCY6)
PHD: 
102341113(ADCY6)
CHX: 
102169557(ADCY6)
OAS: 
101105735(ADCY6)
SSC: 
100522613(ADCY6)
CFR: 
102519611(ADCY6)
CDK: 
105103816(ADCY6)
BACU: 
103014094(ADCY6)
LVE: 
103075153(ADCY6)
ECB: 
100051295(ADCY6)
EPZ: 
103563634(ADCY6)
EAI: 
106836825(ADCY6)
MYB: 
102248773(ADCY6)
MYD: 
102766123(ADCY6)
HAI: 
109393238(ADCY6)
RSS: 
109443844(ADCY6)
PALE: 
102890588(ADCY6)
LAV: 
100653532(ADCY6)
SHR: 
100932634(ADCY6)
OAA: 
100081118(ADCY6)
CJO: 
107307087(ADCY6)
GFR: 
102033025(ADCY6)
FAB: 
101810909(ADCY6)
PHI: 
102101002(ADCY6)
PMAJ: 
107198603(ADCY6)
FPG: 
101916278(ADCY6)
FCH: 
102050328(ADCY6)
CLV: 
102092552(ADCY6)
ASN: 
102388125(ADCY6)
AMJ: 
102573402(ADCY6)
PSS: 
102448834(ADCY6)
CMY: 
102942183(ADCY6)
CPIC: 
101948443(ADCY6)
ACS: 
100558069(adcy6)
PVT: 
110074939(ADCY6)
PBI: 
103050190(ADCY6)
GJA: 
107120916(ADCY6)
XLA: 
108708542 414728(adcy6.L)
XTR: 
100493933(adcy6)
NPR: 
DRE: 
560807(adcy6b) 570652(adcy6a)
SRX: 
SANH: 
SGH: 
IPU: 
108276068(ADCY6)
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102366154(ADCY6)
CMK: 
DGR: 
NAI: 
NVE: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wicker R, Catalan AG, Cailleux A, Starenki D, Stengel D, Sarasin A, Suarez HG
  Title
Cloning and expression of human adenylyl cyclase type VI in normal thyroid tissues.
  Journal
Biochim Biophys Acta 1493:279-83 (2000)
DOI:10.1016/S0167-4781(00)00187-1
  Sequence
[hsa:112]
Reference
  Authors
Ding Q, Gros R, Gray ID, Taussig R, Ferguson SS, Feldman RD
  Title
Raf kinase activation of adenylyl cyclases: isoform-selective regulation.
  Journal
Mol Pharmacol 66:921-8 (2004)
DOI:10.1124/mol.66.4.921

KEGG   ORTHOLOGY: K08047Help
Entry
K08047                      KO                                     

Name
ADCY7
Definition
adenylate cyclase 7 [EC:4.6.1.1]
Pathway
Purine metabolism
Endocrine resistance
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Apelin signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Aldosterone synthesis and secretion
Relaxin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy (DCM)
Module
M00695  
cAMP signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08047  ADCY7; adenylate cyclase 7
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04371 Apelin signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04020 Calcium signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04072 Phospholipase D signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04024 cAMP signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04022 cGMP - PKG signaling pathway
    K08047  ADCY7; adenylate cyclase 7
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08047  ADCY7; adenylate cyclase 7
  Cellular community - eukaryotes
   04540 Gap junction
    K08047  ADCY7; adenylate cyclase 7
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08047  ADCY7; adenylate cyclase 7
   04062 Chemokine signaling pathway
    K08047  ADCY7; adenylate cyclase 7
  Endocrine system
   04911 Insulin secretion
    K08047  ADCY7; adenylate cyclase 7
   04923 Regulation of lipolysis in adipocyte
    K08047  ADCY7; adenylate cyclase 7
   04912 GnRH signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04913 Ovarian Steroidogenesis
    K08047  ADCY7; adenylate cyclase 7
   04915 Estrogen signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04914 Progesterone-mediated oocyte maturation
    K08047  ADCY7; adenylate cyclase 7
   04921 Oxytocin signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04926 Relaxin signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04918 Thyroid hormone synthesis
    K08047  ADCY7; adenylate cyclase 7
   04916 Melanogenesis
    K08047  ADCY7; adenylate cyclase 7
   04925 Aldosterone synthesis and secretion
    K08047  ADCY7; adenylate cyclase 7
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08047  ADCY7; adenylate cyclase 7
   04270 Vascular smooth muscle contraction
    K08047  ADCY7; adenylate cyclase 7
  Digestive system
   04970 Salivary secretion
    K08047  ADCY7; adenylate cyclase 7
   04971 Gastric acid secretion
    K08047  ADCY7; adenylate cyclase 7
   04972 Pancreatic secretion
    K08047  ADCY7; adenylate cyclase 7
   04976 Bile secretion
    K08047  ADCY7; adenylate cyclase 7
  Nervous system
   04724 Glutamatergic synapse
    K08047  ADCY7; adenylate cyclase 7
   04727 GABAergic synapse
    K08047  ADCY7; adenylate cyclase 7
   04725 Cholinergic synapse
    K08047  ADCY7; adenylate cyclase 7
   04723 Retrograde endocannabinoid signaling
    K08047  ADCY7; adenylate cyclase 7
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08047  ADCY7; adenylate cyclase 7
  Aging
   04211 Longevity regulating pathway - mammal
    K08047  ADCY7; adenylate cyclase 7
   04213 Longevity regulating pathway - multiple species
    K08047  ADCY7; adenylate cyclase 7
  Environmental adaptation
   04713 Circadian entrainment
    K08047  ADCY7; adenylate cyclase 7
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08047  ADCY7; adenylate cyclase 7
  Substance dependence
   05032 Morphine addiction
    K08047  ADCY7; adenylate cyclase 7
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08047  ADCY7; adenylate cyclase 7
  Infectious diseases
   05166 HTLV-I infection
    K08047  ADCY7; adenylate cyclase 7
  Drug resistance
   01522 Endocrine resistance
    K08047  ADCY7; adenylate cyclase 7
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00695  cAMP signaling
     K08047  ADCY7; adenylate cyclase 7
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08047  ADCY7; adenylate cyclase 7
BRITE hierarchy
Other DBs
Genes
HSA: 
113(ADCY7)
PTR: 
473278(ADCY7)
PPS: 
100984225(ADCY7)
GGO: 
101126268(ADCY7)
PON: 
100436577(ADCY7)
NLE: 
100587036(ADCY7)
MCC: 
694730(ADCY7)
MCF: 
102125718(ADCY7)
CSAB: 
103232667(ADCY7)
RRO: 
104672569(ADCY7)
RBB: 
108522948(ADCY7)
CJC: 
100404620(ADCY7)
SBQ: 
101032672(ADCY7)
MMU: 
11513(Adcy7)
RNO: 
84420(Adcy7)
CGE: 
100756132(Adcy7)
NGI: 
103730120(Adcy7)
HGL: 
101712483(Adcy7)
CCAN: 
109698373(Adcy7)
OCU: 
100357357(ADCY7)
TUP: 
102496578(ADCY7)
CFA: 
487289(ADCY7)
AML: 
100466965(ADCY7)
UMR: 
103673916(ADCY7)
FCA: 
101094148(ADCY7)
PTG: 
102972917(ADCY7)
AJU: 
106985835(ADCY7)
BTA: 
281603(ADCY7)
BOM: 
102266966(ADCY7)
BIU: 
109572478(ADCY7)
PHD: 
102326057(ADCY7)
CHX: 
102185858(ADCY7)
OAS: 
101112667(ADCY7)
SSC: 
100620994(ADCY7)
CFR: 
102524614(ADCY7)
CDK: 
105097528(ADCY7)
BACU: 
102997912(ADCY7)
LVE: 
103078677(ADCY7)
ECB: 
100058891(ADCY7)
EPZ: 
103556685(ADCY7)
EAI: 
106824126(ADCY7)
MYB: 
102253549(ADCY7)
MYD: 
102764043(ADCY7)
HAI: 
109383261(ADCY7)
RSS: 
109447700(ADCY7)
PALE: 
102881535(ADCY7)
LAV: 
100653771(ADCY7)
MDO: 
100013823(ADCY7)
SHR: 
100929278(ADCY7)
OAA: 
100076221(ADCY7)
GGA: 
415732(ADCY7)
MGP: 
100548914(ADCY7)
CJO: 
107319017(ADCY7)
APLA: 
101794076(ADCY7)
ACYG: 
106039584(ADCY7)
TGU: 
100225700(ADCY7)
GFR: 
102043194(ADCY7)
FAB: 
101816007(ADCY7)
PHI: 
102106688(ADCY7)
PMAJ: 
107209841(ADCY7)
CCW: 
104687454(ADCY7)
FPG: 
101914615(ADCY7)
FCH: 
102052224(ADCY7)
CLV: 
102090470(ADCY7)
AAM: 
106483289(ADCY7)
ASN: 
102368976(ADCY7)
AMJ: 
102566330(ADCY7)
PSS: 
102449192(ADCY7)
CMY: 
102946407(ADCY7)
CPIC: 
101938536(ADCY7)
ACS: 
100558751(adcy7)
PVT: 
110086573(ADCY7)
PBI: 
GJA: 
107117185(ADCY7)
XLA: 
399055(adcy7.L)
XTR: 
100127741(adcy7)
NPR: 
108794932(ADCY7)
DRE: 
568726(adcy7)
SRX: 
SANH: 
SGH: 
IPU: 
108259218(adcy7)
TRU: 
101066272(adcy7)
TNG: 
LCO: 
104940647(adcy7)
MZE: 
101480238(adcy7)
OLA: 
101164967(adcy7)
XMA: 
102223009(adcy7)
CSEM: 
LCF: 
108876970(adcy7)
HCQ: 
109513976(adcy7)
BPEC: 
110175272(adcy7)
SASA: 
ELS: 
105025700(adcy7)
SFM: 
LCM: 
102351065(ADCY7)
CMK: 
103176081(adcy7)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7961850
  Authors
Watson PA, Krupinski J, Kempinski AM, Frankenfield CD
  Title
Molecular cloning and characterization of the type VII isoform of mammalian adenylyl cyclase expressed widely in mouse tissues and in S49 mouse lymphoma cells.
  Journal
J Biol Chem 269:28893-8 (1994)
  Sequence
[hsa:113]
Reference
  Authors
Joeyen-Waldorf J, Nikolova YS, Edgar N, Walsh C, Kota R, Lewis DA, Ferrell R, Manuck SB, Hariri AR, Sibille E
  Title
Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry.
  Journal
Biol Psychiatry 71:627-32 (2012)
DOI:10.1016/j.biopsych.2011.11.029

KEGG   ORTHOLOGY: K08048Help
Entry
K08048                      KO                                     

Name
ADCY8
Definition
adenylate cyclase 8 [EC:4.6.1.1]
Pathway
Purine metabolism
Endocrine resistance
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Apelin signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Aldosterone synthesis and secretion
Relaxin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy (DCM)
Module
M00695  
cAMP signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08048  ADCY8; adenylate cyclase 8
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04371 Apelin signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04020 Calcium signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04072 Phospholipase D signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04024 cAMP signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04022 cGMP - PKG signaling pathway
    K08048  ADCY8; adenylate cyclase 8
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08048  ADCY8; adenylate cyclase 8
  Cellular community - eukaryotes
   04540 Gap junction
    K08048  ADCY8; adenylate cyclase 8
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08048  ADCY8; adenylate cyclase 8
   04062 Chemokine signaling pathway
    K08048  ADCY8; adenylate cyclase 8
  Endocrine system
   04911 Insulin secretion
    K08048  ADCY8; adenylate cyclase 8
   04923 Regulation of lipolysis in adipocyte
    K08048  ADCY8; adenylate cyclase 8
   04912 GnRH signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04913 Ovarian Steroidogenesis
    K08048  ADCY8; adenylate cyclase 8
   04915 Estrogen signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04914 Progesterone-mediated oocyte maturation
    K08048  ADCY8; adenylate cyclase 8
   04921 Oxytocin signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04926 Relaxin signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04918 Thyroid hormone synthesis
    K08048  ADCY8; adenylate cyclase 8
   04916 Melanogenesis
    K08048  ADCY8; adenylate cyclase 8
   04925 Aldosterone synthesis and secretion
    K08048  ADCY8; adenylate cyclase 8
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08048  ADCY8; adenylate cyclase 8
   04270 Vascular smooth muscle contraction
    K08048  ADCY8; adenylate cyclase 8
  Digestive system
   04970 Salivary secretion
    K08048  ADCY8; adenylate cyclase 8
   04971 Gastric acid secretion
    K08048  ADCY8; adenylate cyclase 8
   04972 Pancreatic secretion
    K08048  ADCY8; adenylate cyclase 8
   04976 Bile secretion
    K08048  ADCY8; adenylate cyclase 8
  Nervous system
   04724 Glutamatergic synapse
    K08048  ADCY8; adenylate cyclase 8
   04727 GABAergic synapse
    K08048  ADCY8; adenylate cyclase 8
   04725 Cholinergic synapse
    K08048  ADCY8; adenylate cyclase 8
   04720 Long-term potentiation
    K08048  ADCY8; adenylate cyclase 8
   04723 Retrograde endocannabinoid signaling
    K08048  ADCY8; adenylate cyclase 8
  Sensory system
   04742 Taste transduction
    K08048  ADCY8; adenylate cyclase 8
   04750 Inflammatory mediator regulation of TRP channels
    K08048  ADCY8; adenylate cyclase 8
  Aging
   04211 Longevity regulating pathway - mammal
    K08048  ADCY8; adenylate cyclase 8
   04213 Longevity regulating pathway - multiple species
    K08048  ADCY8; adenylate cyclase 8
  Environmental adaptation
   04713 Circadian entrainment
    K08048  ADCY8; adenylate cyclase 8
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08048  ADCY8; adenylate cyclase 8
  Substance dependence
   05032 Morphine addiction
    K08048  ADCY8; adenylate cyclase 8
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08048  ADCY8; adenylate cyclase 8
  Infectious diseases
   05166 HTLV-I infection
    K08048  ADCY8; adenylate cyclase 8
  Drug resistance
   01522 Endocrine resistance
    K08048  ADCY8; adenylate cyclase 8
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00695  cAMP signaling
     K08048  ADCY8; adenylate cyclase 8
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08048  ADCY8; adenylate cyclase 8
BRITE hierarchy
Other DBs
Genes
HSA: 
114(ADCY8)
PTR: 
464400(ADCY8)
PPS: 
100994715(ADCY8)
GGO: 
101142672(ADCY8)
PON: 
NLE: 
100592592(ADCY8)
MCC: 
695792(ADCY8)
MCF: 
102144854(ADCY8)
CSAB: 
103237447(ADCY8)
RRO: 
RBB: 
108514094(ADCY8)
CJC: 
100404484(ADCY8)
SBQ: 
101034552(ADCY8)
MMU: 
11514(Adcy8)
RNO: 
29241(Adcy8)
CGE: 
NGI: 
103743923(Adcy8)
HGL: 
101698293(Adcy8)
CCAN: 
109678665(Adcy8)
OCU: 
100337882(ADCY8)
TUP: 
102472317(ADCY8)
CFA: 
482045(ADCY8)
AML: 
100474121(ADCY8)
UMR: 
103661704(ADCY8)
FCA: 
101087555(ADCY8)
PTG: 
102948581(ADCY8)
AJU: 
106976879(ADCY8)
BTA: 
535017(ADCY8)
BOM: 
102272964(ADCY8)
BIU: 
109568647(ADCY8)
PHD: 
102315306(ADCY8)
CHX: 
102184919(ADCY8)
OAS: 
101121944(ADCY8)
SSC: 
100622999(ADCY8)
CFR: 
102521259(ADCY8)
CDK: 
105096450(ADCY8)
BACU: 
103019172(ADCY8)
LVE: 
103085845(ADCY8)
ECB: 
100057796(ADCY8)
EPZ: 
EAI: 
106824833(ADCY8)
MYB: 
102249345(ADCY8)
MYD: 
102765722(ADCY8)
HAI: 
109372359(ADCY8)
RSS: 
109443475(ADCY8)
PALE: 
102896789(ADCY8)
LAV: 
100661616(ADCY8)
MDO: 
100026554(ADCY8)
SHR: 
100923926(ADCY8)
OAA: 
100077908(ADCY8)
GGA: 
420328(ADCY8)
MGP: 
100548951(ADCY8)
CJO: 
107310566(ADCY8)
APLA: 
101794043(ADCY8)
ACYG: 
106046364(ADCY8)
TGU: 
100230277(ADCY8)
GFR: 
102037430(ADCY8)
FAB: 
101809046(ADCY8)
PHI: 
102108193(ADCY8)
PMAJ: 
107200813(ADCY8)
CCW: 
104692638(ADCY8)
FPG: 
101921528(ADCY8)
FCH: 
102056487(ADCY8)
CLV: 
102086133(ADCY8)
AAM: 
106496221(ADCY8)
ASN: 
102369910(ADCY8)
AMJ: 
102562540(ADCY8)
PSS: 
CMY: 
102930804(ADCY8)
CPIC: 
101947738(ADCY8)
ACS: 
100556578(adcy8)
PVT: 
110090751(ADCY8)
PBI: 
GJA: 
107119214(ADCY8)
XLA: 
108719413 414729(adcy8.S)
XTR: 
NPR: 
108788952(ADCY8)
DRE: 
100148976(adcy8) 560410(si:ch211-132f19.7) 560719(si:dkey-206f10.1)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102346737(ADCY8)
CMK: 
103183440(adcy8)
BFO: 
CIN: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DSE: 
DSI: 
Dsimw501_GD12142(Dsim_GD12142)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
726262(GB19497)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
DPX: 
ISC: 
TUT: 
LAK: 
AQU: 
DFA: 
DFA_04345(acaA)
SPAR: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8076676
  Authors
Defer N, Marinx O, Stengel D, Danisova A, Iourgenko V, Matsuoka I, Caput D, Hanoune J
  Title
Molecular cloning of the human type VIII adenylyl cyclase.
  Journal
FEBS Lett 351:109-13 (1994)
DOI:10.1016/0014-5793(94)00836-1
  Sequence
[hsa:114]
Reference
  Authors
Roger B, Papin J, Vacher P, Raoux M, Mulot A, Dubois M, Kerr-Conte J, Voy BH, Pattou F, Charpentier G, Jonas JC, Moustaid-Moussa N, Lang J
  Title
Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells.
  Journal
Diabetologia 54:390-402 (2011)
DOI:10.1007/s00125-010-1955-x

KEGG   ORTHOLOGY: K08049Help
Entry
K08049                      KO                                     

Name
ADCY9
Definition
adenylate cyclase 9 [EC:4.6.1.1]
Pathway
Purine metabolism
Endocrine resistance
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Phospholipase D signaling pathway
Oocyte meiosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Apelin signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Regulation of lipolysis in adipocytes
Aldosterone synthesis and secretion
Relaxin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
Vibrio cholerae infection
HTLV-I infection
Pathways in cancer
Dilated cardiomyopathy (DCM)
Module
M00695  
cAMP signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08049  ADCY9; adenylate cyclase 9
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04371 Apelin signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04020 Calcium signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04072 Phospholipase D signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04024 cAMP signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04022 cGMP - PKG signaling pathway
    K08049  ADCY9; adenylate cyclase 9
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08049  ADCY9; adenylate cyclase 9
  Cellular community - eukaryotes
   04540 Gap junction
    K08049  ADCY9; adenylate cyclase 9
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08049  ADCY9; adenylate cyclase 9
   04062 Chemokine signaling pathway
    K08049  ADCY9; adenylate cyclase 9
  Endocrine system
   04911 Insulin secretion
    K08049  ADCY9; adenylate cyclase 9
   04923 Regulation of lipolysis in adipocyte
    K08049  ADCY9; adenylate cyclase 9
   04912 GnRH signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04913 Ovarian Steroidogenesis
    K08049  ADCY9; adenylate cyclase 9
   04915 Estrogen signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04914 Progesterone-mediated oocyte maturation
    K08049  ADCY9; adenylate cyclase 9
   04921 Oxytocin signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04926 Relaxin signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04918 Thyroid hormone synthesis
    K08049  ADCY9; adenylate cyclase 9
   04916 Melanogenesis
    K08049  ADCY9; adenylate cyclase 9
   04925 Aldosterone synthesis and secretion
    K08049  ADCY9; adenylate cyclase 9
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08049  ADCY9; adenylate cyclase 9
   04270 Vascular smooth muscle contraction
    K08049  ADCY9; adenylate cyclase 9
  Digestive system
   04970 Salivary secretion
    K08049  ADCY9; adenylate cyclase 9
   04971 Gastric acid secretion
    K08049  ADCY9; adenylate cyclase 9
   04972 Pancreatic secretion
    K08049  ADCY9; adenylate cyclase 9
   04976 Bile secretion
    K08049  ADCY9; adenylate cyclase 9
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    K08049  ADCY9; adenylate cyclase 9
   04961 Endocrine and other factor-regulated calcium reabsorption
    K08049  ADCY9; adenylate cyclase 9
  Nervous system
   04724 Glutamatergic synapse
    K08049  ADCY9; adenylate cyclase 9
   04727 GABAergic synapse
    K08049  ADCY9; adenylate cyclase 9
   04725 Cholinergic synapse
    K08049  ADCY9; adenylate cyclase 9
   04723 Retrograde endocannabinoid signaling
    K08049  ADCY9; adenylate cyclase 9
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08049  ADCY9; adenylate cyclase 9
  Aging
   04211 Longevity regulating pathway - mammal
    K08049  ADCY9; adenylate cyclase 9
   04213 Longevity regulating pathway - multiple species
    K08049  ADCY9; adenylate cyclase 9
  Environmental adaptation
   04713 Circadian entrainment
    K08049  ADCY9; adenylate cyclase 9
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08049  ADCY9; adenylate cyclase 9
  Substance dependence
   05032 Morphine addiction
    K08049  ADCY9; adenylate cyclase 9
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08049  ADCY9; adenylate cyclase 9
  Infectious diseases
   05110 Vibrio cholerae infection
    K08049  ADCY9; adenylate cyclase 9
   05166 HTLV-I infection
    K08049  ADCY9; adenylate cyclase 9
  Drug resistance
   01522 Endocrine resistance
    K08049  ADCY9; adenylate cyclase 9
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00695  cAMP signaling
     K08049  ADCY9; adenylate cyclase 9
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08049  ADCY9; adenylate cyclase 9
BRITE hierarchy
Other DBs
Genes
HSA: 
115(ADCY9)
PTR: 
453869(ADCY9)
PPS: 
100972356(ADCY9)
GGO: 
101145410(ADCY9)
PON: 
NLE: 
100599484(ADCY9)
MCC: 
706789(ADCY9)
MCF: 
CSAB: 
103227576(ADCY9)
RRO: 
104672288(ADCY9)
RBB: 
108538326(ADCY9)
CJC: 
100405403(ADCY9)
SBQ: 
101052034(ADCY9)
MMU: 
11515(Adcy9)
RNO: 
302950(Adcy9)
CGE: 
100751372(Adcy9)
NGI: 
103744458(Adcy9)
HGL: 
101714605(Adcy9)
CCAN: 
OCU: 
100340877(ADCY9)
TUP: 
102477344(ADCY9)
CFA: 
490031(ADCY9)
AML: 
100476495(ADCY9)
UMR: 
103668547(ADCY9)
FCA: 
101095942(ADCY9)
PTG: 
102969003(ADCY9)
AJU: 
106978803(ADCY9)
BTA: 
525482(ADCY9)
BOM: 
102285642(ADCY9)
BIU: 
109578364(ADCY9)
PHD: 
CHX: 
102188104(ADCY9)
OAS: 
101122401(ADCY9)
SSC: 
100625423(ADCY9)
CFR: 
102505261(ADCY9)
CDK: 
105099828(ADCY9)
BACU: 
103016058(ADCY9)
LVE: 
103070451(ADCY9)
ECB: 
100066046(ADCY9)
EPZ: 
103553014(ADCY9)
EAI: 
106826021(ADCY9)
MYB: 
102248953(ADCY9)
MYD: 
102760324(ADCY9)
HAI: 
109392133(ADCY9)
RSS: 
109436708(ADCY9)
PALE: 
102885676(ADCY9)
LAV: 
100663448(ADCY9)
MDO: 
100013831(ADCY9)
SHR: 
100926025(ADCY9)
OAA: 
GGA: 
395339(ADCY9)
MGP: 
CJO: 
107320968(ADCY9)
APLA: 
101800617(ADCY9)
ACYG: 
106033354(ADCY9)
TGU: 
100231171(ADCY9)
GFR: 
102043312(ADCY9)
FAB: 
101818533(ADCY9)
PHI: 
102103610(ADCY9)
PMAJ: 
107211136(ADCY9)
CCW: 
104684954(ADCY9)
FPG: 
101921768(ADCY9)
FCH: 
102047847(ADCY9)
CLV: 
102095574(ADCY9)
AAM: 
106482327(ADCY9)
ASN: 
AMJ: 
102574362(ADCY9)
PSS: 
102448197(ADCY9)
CMY: 
CPIC: 
101940138(ADCY9)
ACS: 
100556223(adcy9)
PVT: 
110089110(ADCY9)
PBI: 
103051661(ADCY9)
GJA: 
107109291(ADCY9)
XLA: 
108703189 378610(adcy9.L)
XTR: 
100126441(adcy9)
NPR: 
108790811(ADCY9)
DRE: 
SRX: 
SANH: 
SGH: 
IPU: 
108259388(adcy9)
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102363182(ADCY9)
CMK: 
103178726(adcy9)
BFO: 
CIN: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD27717(Dsim_GD27717)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
PHU: 
DPX: 
ISC: 
CEL: 
CBR: 
CBG18000(Cbr-acy-1)
NAI: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
ADF: 
HMG: 
TAD: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9628827
  Authors
Hacker BM, Tomlinson JE, Wayman GA, Sultana R, Chan G, Villacres E, Disteche C, Storm DR
  Title
Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9).
  Journal
Genomics 50:97-104 (1998)
DOI:10.1006/geno.1998.5293
  Sequence
[hsa:115]

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