KEGG ORTHOLOGY: K08063

ORTHOLOGY: K08063

Entry

K08063                      KO

Symbol

RFXAP

Name

regulatory factor X-associated protein

Pathway

map04612

Antigen processing and presentation

map05152

Tuberculosis

map05340

Primary immunodeficiency

Disease

H00985

Bare lymphocyte syndrome type2

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K08063  RFXAP; regulatory factor X-associated protein
09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K08063  RFXAP; regulatory factor X-associated protein
  09163 Immune disease
   05340 Primary immunodeficiency
    K08063  RFXAP; regulatory factor X-associated protein

Genes

HSA:	5994(RFXAP)

PTR:	100610983(RFXAP)

PPS:	100984854(RFXAP)

GGO:	101138043(RFXAP)

PON:	100450280(RFXAP)

NLE:	100582394(RFXAP)

HMH:	116467079(RFXAP)

MCC:	694441(RFXAP)

MCF:

102138204

MTHB:

126940314

MNI:	105486041(RFXAP)

CSAB:

103214283(RFXAP)

CATY:

105587865(RFXAP)

PANU:

101004422(RFXAP)

TGE:	112610875(RFXAP)

MLEU:

105548797(RFXAP)

RRO:	104677939(RFXAP)

RBB:	108516591(RFXAP)

TFN:	117097323(RFXAP)

PTEH:

111540491(RFXAP)

CANG:

105512540(RFXAP)

CJC:	100393775(RFXAP)

SBQ:	101027776(RFXAP)

CIMI:

108310787

MMUR:

105862082(RFXAP)

LCAT:

123649092

PCOQ:

105810125(RFXAP)

OGA:	100944066(RFXAP)

MMU:	170767(Rfxap)

MCAL:

110291319(Rfxap)

MPAH:

110320546(Rfxap)

RNO:	499617(Rfxap)

MCOC:

116092874(Rfxap)

ANU:	117707613(Rfxap)

MUN:	110554912(Rfxap)

CGE:	100774659(Rfxap)

MAUA:

101823038

PROB:

127216334(Rfxap)

PLEU:

MORG:

MFOT:

AAMP:

NGI:	103752221(Rfxap)

HGL:	101719989(Rfxap)

CPOC:

100717309(Rfxap)

CCAN:

109699608(Rfxap)

DORD:

105997133(Rfxap)

DSP:

PLOP:

NCAR:

MMMA:

OCU:

OPI:

TUP:	102484630(RFXAP)

GVR:	103606841(RFXAP)

CFA:	607367(RFXAP)

CLUD:

112670174

VVP:	112918543(RFXAP)

VLG:

121497710

NPO:	129504517(RFXAP)

AML:	100475849(RFXAP)

UMR:

103664419

UAH:	113251009(RFXAP)

UAR:

123791799

ELK:

111158537

LLV:

125095617

MPUF:

101691297(RFXAP)

MNP:	132002961(RFXAP)

MLK:	131813818(RFXAP)

NVS:

122907026

ORO:	101375274(RFXAP)

EJU:	114209262(RFXAP)

ZCA:

113920434

MLX:	118009506(RFXAP)

NSU:

110570217

LWW:	102736882(RFXAP)

FCA:	101088294(RFXAP)

PYU:

121012650

PCOO:

112860842(RFXAP)

PBG:

122476973

PVIV:

125163493(RFXAP)

LRUF:

124508332

PTG:	102967387(RFXAP)

PPAD:

109265816(RFXAP)

PUC:

125934000

AJU:

106973843

HHV:

120246209

BTA:	540760(RFXAP)

BIU:	109566774(RFXAP)

BBUB:

102412691

CHX:	102185753(RFXAP)

OAS:	105612445(RFXAP)

BTAX:

128057741(RFXAP)

ODA:

120883112

CCAD:

122447069

MBEZ:

129556325(RFXAP)

SSC:	100155648(RFXAP)

CFR:	102520757(RFXAP)

CBAI:

105066308(RFXAP)

CDK:	105100832(RFXAP)

VPC:	102529776(RFXAP)

BACU:

103020095(RFXAP)

BMUS:

118884400

LVE:	103077390(RFXAP)

OOR:	101287764(RFXAP)

DLE:	111175071(RFXAP)

PCAD:

102974203(RFXAP)

PSIU:

116749884

NASI:

112409269

EPZ:	103559383(RFXAP)

EAI:

106844942

MYB:	102243528(RFXAP) 106725997

MYD:	102753562(RFXAP)

MMYO:

118650050

MLF:	102428345(RFXAP)

PKL:

118728723

EFUS:

103303304(RFXAP)

MNA:	107525164(RFXAP)

DRO:	112313590(RFXAP)

SHON:

AJM:

PDIC:

PHAS:

MMF:

PPAM:

129081143(RFXAP)

HAI:	109388472(RFXAP)

RFQ:	117021063(RFXAP)

PALE:

102898769(RFXAP)

PGIG:

120610613

PVP:	105293314(RFXAP)

RAY:	107503949(RFXAP)

TOD:	119258530(RFXAP)

SARA:

101539233(RFXAP)

SETR:

126015935(RFXAP)

LAV:	100658303(RFXAP)

TMU:

101345853

ETF:

101664682

DNM:	101432051(RFXAP)

MDO:	100027231(RFXAP)

GAS:

123241257

SHR:	100920977(RFXAP)

AFZ:

127555244

PCW:	110195160(RFXAP)

OAA:

100080809

GGA:	418899(RFXAP)

PCOC:

116244162(RFXAP)

CJO:	107306771(RFXAP)

TPAI:

128074839(RFXAP)

LMUT:

125694886

NMEL:

110402808(RFXAP)

APLA:

101800567

ACYG:

125185055

CATA:

118246026(RFXAP)

AFUL:

116501334(RFXAP)

TGU:	101234225(RFXAP)

LSR:	110476700(RFXAP)

SCAN:

103812558(RFXAP)

PMOA:

120496306

OTC:

121337267

PRUF:

121353247

FAB:	101806274(RFXAP)

OMA:	130253238(RFXAP)

PMAJ:

107209746(RFXAP)

CCW:

104689928

ETL:	114060971(RFXAP)

SVG:	106865352(RFXAP)

MMEA:

130578553(RFXAP)

HRT:	120748639(RFXAP)

TALA:

ACHC:

AGEN:

GCL:

SHAB:

115604511(RFXAP)

RTD:	128913404(RFXAP)

NPD:	112942882(RFXAP)

DNE:	112982142(RFXAP)

AMJ:	102570327(RFXAP)

CMY:

CCAY:

DCC:

CPIC:

TST:	117871030(RFXAP)

CABI:

116839744(RFXAP)

MRV:

120401683

ACS:	103278417(rfxap)

ASAO:

132772083(RFXAP)

PVT:	110074023(RFXAP)

SUND:

121926989

PBI:	103048639(RFXAP)

PMUR:

107287661(RFXAP)

CTIG:

120300827

TSR:	106545914(RFXAP)

PGUT:

117662136(RFXAP)

APRI:

131200054(RFXAP)

PTEX:

113441745(RFXAP)

NSS:	113421489(RFXAP)

VKO:

123029553

PMUA:

114595806(RFXAP)

PRAF:

128412745(RFXAP)

ZVI:	118085782(RFXAP)

HCG:	128352040(RFXAP)

GJA:	107106040(RFXAP)

STOW:

125432056

EMC:	129325448(RFXAP)

XLA:	108709940(rfxap.S)

XTR:	100379771(rfxap)

NPR:	108785355(RFXAP)

RTEM:

120929140

BBUF:

120996288

BGAR:

122931146

MUO:	115468582(RFXAP)

GSH:	117362855(RFXAP)

DRE:	100006212(rfxap)

SRX:	107728283 107728874 107734457(rfxap)

SANH:

107686162(rfxap) 107697413

SGH:	107578759 107589095

CCAR:

CAUA:

CGIB:

PTET:

LROH:

127172122(rfxap)

OMC:	131548634(rfxap)

PPRM:

120482693

RKG:	130074093(rfxap)

MAMB:

125262767

CIDE:

127521532

MASI:

127432946 127433679

TROS:

130546625(rfxap)

TDW:	130411515(rfxap)

MANU:

129446780(rfxap)

IPU:

108276696

IFU:	128620352(rfxap)

PHYP:

113543604(rfxap)

SMEO:

124393606

TFD:

113638030

TVC:	132863096(rfxap)

AMEX:

103039202(rfxap)

CMAO:

118824552

EEE:	113572180(rfxap)

CHAR:

105896329

TRU:	101075394(rfxap)

TFS:	130537962(rfxap)

TNG:	GSTEN00018868G001

LCO:	104928218(rfxap)

NCC:	104964550(rfxap)

TBEN:

117490436(rfxap)

CGOB:

115019327(rfxap)

PGEO:

117458522(rfxap)

GACU:

117535137(rfxap)

EMAC:

134872431(rfxap)

ELY:	117271275(rfxap)

EFO:

125898419

PLEP:

121963486

SLUC:

116037130

ECRA:

117955437(rfxap)

ESP:	116701152(rfxap)

PFLV:

114567182(rfxap)

GAT:

120822385

PPUG:

119215906

AFB:	129113463(rfxap)

CLUM:

117742489(rfxap)

PSWI:

130188574(rfxap)

MSAM:

SCHU:

CUD:

ALAT:

MZE:	101471661(rfxap)

ONL:	100704569(rfxap)

OAU:

116311904

OLA:	101167388(rfxap)

OML:

112139895

CSAI:

133459442 133459554

XMA:	102218213(rfxap)

XCO:	114153306(rfxap)

XHE:	116728703(rfxap)

PRET:

103475560(rfxap)

PFOR:

103140050 103140107(rfxap)

PLAI:

106951405(rfxap)

PMEI:

106922235(rfxap)

GAF:

122844505

PPRL:

129373607(rfxap)

CVG:	107088285(rfxap)

CTUL:

119779216

GMU:

124876473

NFU:	107391187(rfxap)

KMR:

108236909

ALIM:

106514161(rfxap)

NWH:

119420563

AOCE:

111566079(rfxap)

MCEP:

125021382

CSEM:

103395221(rfxap) 103399480

POV:	109635807(rfxap)

SSEN:

122779557

HHIP:

117774126(rfxap)

HSP:

118122094

SMAU:

118300872

LCF:

108893716

SDU:	111217127(rfxap)

SLAL:

111662677(rfxap)

XGL:

120802587

HCQ:	109515632(rfxap)

SSCV:

125982575

SBIA:

133492160(rfxap)

PEE:	133416121(rfxap)

PTAO:

133467599(rfxap)

BPEC:

110158608(rfxap)

MALB:

109971886(rfxap)

BSPL:

114869072(rfxap)

SJO:	128371351(rfxap)

SASA:

106563855(rfxap) 106604035

STRU:

115153827 115204639

OTW:	112238481(rfxap) 112239533

OMY:	110510256 110533260

OGO:	123995231 124007444

ONE:	115123809 115125633

OKI:	109873981(rfxap) 109881529

OKE:	118362200 118384885(rfxap)

SALP:

112072828 112076117

SNH:	120021647 120056819

CCLU:

121542048 121555391

ELS:	105029978(rfxap)

SFM:	108936053(rfxap)

PKI:	111840452(rfxap)

AANG:

118236196(rfxap)

LOC:	102690257(rfxap)

PSPA:

121321372

ARUT:

117406047 117406921

PSEX:

120524015

LCM:	102346053(RFXAP)

CMK:

103177191

CPLA:

122551070

HOC:	132816492(rfxap)

LERI:

129698013(rfxap)

PMRN:

LRJ:

BFO:

BBEL:

SPU:

APLC:

SKO:

HAME:

PTRU:

PCAN:

MYI:

PMAX:

DGT:

Reference

PMID:9118943

Authors

Durand B, Sperisen P, Emery P, Barras E, Zufferey M, Mach B, Reith W

Title

RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency.

Journal

EMBO J 16:1045-55 (1997)
DOI:10.1093/emboj/16.5.1045

Sequence

[hsa:5994]

Reference

PMID:20024540

Authors

Bushway M, Cycon KA, Mulvaney K, Murphy SP

Title

Coordinate loss of MHC class II expression in the diffuse large B cell lymphoma cell line OCI-Ly2 is due to a novel mutation in RFX-AP.

Journal

Immunogenetics 62:109-16 (2010)
DOI:10.1007/s00251-009-0418-3

Sequence

[hsa:5994]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (451)   
   KEGG GENES (369)   
   KEGG MGENES (32)   
   RefGene (48)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (461)   

Download RDF

DBGET integrated database retrieval system