KEGG   ORTHOLOGY: K08523Help
Entry
K08523                      KO                                     

Name
HBEGF
Definition
heparin-binding EGF-like growth factor
Pathway
Endocrine resistance
ErbB signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Epithelial cell signaling in Helicobacter pylori infection
Proteoglycans in cancer
Bladder cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    K08523  HBEGF; heparin-binding EGF-like growth factor
 Organismal Systems
  Endocrine system
   04912 GnRH signaling pathway
    K08523  HBEGF; heparin-binding EGF-like growth factor
   04915 Estrogen signaling pathway
    K08523  HBEGF; heparin-binding EGF-like growth factor
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K08523  HBEGF; heparin-binding EGF-like growth factor
   05219 Bladder cancer
    K08523  HBEGF; heparin-binding EGF-like growth factor
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K08523  HBEGF; heparin-binding EGF-like growth factor
  Drug resistance
   01522 Endocrine resistance
    K08523  HBEGF; heparin-binding EGF-like growth factor
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Growth factors/receptors
   K08523  HBEGF; heparin-binding EGF-like growth factor
BRITE hierarchy
Genes
HSA: 
1839(HBEGF)
PTR: 
735979(HBEGF)
PPS: 
100977885(HBEGF)
GGO: 
101138938(HBEGF)
PON: 
100437870(HBEGF)
NLE: 
100600047(HBEGF)
MCC: 
695559(HBEGF)
MCF: 
102120009(HBEGF)
CSAB: 
103244654(HBEGF)
RRO: 
104681756(HBEGF)
RBB: 
108530840(HBEGF)
CJC: 
100392997(HBEGF)
SBQ: 
101029484(HBEGF)
MMU: 
15200(Hbegf)
RNO: 
25433(Hbegf)
CGE: 
100689423(Hbegf)
NGI: 
103743072(Hbegf)
HGL: 
101699647(Hbegf)
CCAN: 
109682066(Hbegf)
OCU: 
100008809(HBEGF)
TUP: 
102498262(HBEGF)
CFA: 
607007(HBEGF)
AML: 
100467713(HBEGF)
UMR: 
103663938(HBEGF)
FCA: 
101093578(HBEGF)
PTG: 
102950862(HBEGF)
AJU: 
106968439(HBEGF)
BTA: 
522921(HBEGF)
BOM: 
102283032(HBEGF)
BIU: 
109562095(HBEGF)
PHD: 
102339878(HBEGF)
CHX: 
102185462(HBEGF)
OAS: 
101118185(HBEGF)
SSC: 
397564(HBEGF)
CFR: 
102510168(HBEGF)
CDK: 
105098108(HBEGF)
BACU: 
102998316(HBEGF)
LVE: 
103074900(HBEGF)
ECB: 
100629956(HBEGF)
EPZ: 
103548009(HBEGF)
EAI: 
106823779(HBEGF)
MYB: 
102244188(HBEGF)
MYD: 
102751834(HBEGF)
HAI: 
109392466(HBEGF)
RSS: 
109451856(HBEGF)
PALE: 
102882842(HBEGF)
LAV: 
100675899(HBEGF)
MDO: 
100026152(HBEGF)
SHR: 
100933188(HBEGF)
OAA: 
100093606(HBEGF)
GGA: 
395654(HBEGF)
MGP: 
100549227(HBEGF)
CJO: 
107320476(HBEGF)
APLA: 
101799901(HBEGF)
ACYG: 
106042744(HBEGF)
TGU: 
100232539(HBEGF)
GFR: 
102031792(HBEGF)
FAB: 
101808558(HBEGF)
PHI: 
102106304(HBEGF)
PMAJ: 
107210893(HBEGF)
CCW: 
104693556(HBEGF)
FPG: 
101923240(HBEGF)
FCH: 
102052533(HBEGF)
CLV: 
102094772(HBEGF)
AAM: 
106494293(HBEGF)
ASN: 
102372604(HBEGF)
AMJ: 
102565343(HBEGF)
PSS: 
102455005(HBEGF)
CMY: 
102931453(HBEGF)
CPIC: 
101934074(HBEGF)
ACS: 
100562149(hbegf)
PVT: 
110082119(HBEGF)
PBI: 
103051348(HBEGF)
GJA: 
107119740(HBEGF)
XLA: 
108710907(hbegf.L) 108713286(hbegf.S)
XTR: 
100497436(hbegf)
DRE: 
797938(hbegfa)
SRX: 
SANH: 
SGH: 
IPU: 
108268609(HBEGF) 108278919(hbegf)
TRU: 
101072713(hbegf)
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
102236217(hbegf)
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102353749(HBEGF)
CMK: 
103186469(hbegf)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1840698
  Authors
Higashiyama S, Abraham JA, Miller J, Fiddes JC, Klagsbrun M
  Title
A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF.
  Journal
Science 251:936-9 (1991)
DOI:10.1126/science.1840698
  Sequence
[hsa:1839]
Reference
  Authors
Iwamoto R, Mekada E
  Title
Heparin-binding EGF-like growth factor: a juxtacrine growth factor.
  Journal
Cytokine Growth Factor Rev 11:335-44 (2000)
DOI:10.1016/S1359-6101(00)00013-7

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