KEGG   ORTHOLOGY: K08733Help
Entry
K08733                      KO                                     

Name
APPL1, DIP13A
Definition
DCC-interacting protein 13 alpha
Pathway
Longevity regulating pathway
Pathways in cancer
Colorectal cancer
Disease
H00410  
Maturity onset diabetes of the young (MODY)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Aging
   04211 Longevity regulating pathway - mammal
    K08733  APPL1, DIP13A; DCC-interacting protein 13 alpha
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08733  APPL1, DIP13A; DCC-interacting protein 13 alpha
   05210 Colorectal cancer
    K08733  APPL1, DIP13A; DCC-interacting protein 13 alpha
Membrane trafficking [BR:ko04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    K08733  APPL1, DIP13A; DCC-interacting protein 13 alpha
BRITE hierarchy
Genes
HSA: 
26060(APPL1)
PTR: 
460469(APPL1)
PPS: 
100995535(APPL1)
GGO: 
101126724(APPL1)
PON: 
100442490(APPL1)
NLE: 
100599415(APPL1)
MCC: 
100425753(APPL1)
MCF: 
102126071(APPL1)
CSAB: 
103227788(APPL1)
RRO: 
104660203(APPL1)
RBB: 
108543582(APPL1)
CJC: 
100389847(APPL1)
SBQ: 
101034147(APPL1)
MMU: 
72993(Appl1)
RNO: 
290537(Appl1)
CGE: 
100751324(Appl1)
NGI: 
103747007(Appl1)
HGL: 
101703342(Appl1)
CCAN: 
OCU: 
100353097(APPL1)
TUP: 
102477144(APPL1)
CFA: 
484716(APPL1)
AML: 
100463883(APPL1)
UMR: 
103675060(APPL1)
FCA: 
101096960(APPL1)
PTG: 
102956094(APPL1)
AJU: 
106967026(APPL1)
BTA: 
517850(APPL1)
BOM: 
102266894(APPL1)
BIU: 
109575959(APPL1)
PHD: 
102343229(APPL1)
CHX: 
102169529(APPL1)
OAS: 
101109218(APPL1)
SSC: 
100188978(APPL1)
CFR: 
102516958(APPL1)
CDK: 
105089793(APPL1)
BACU: 
103012463(APPL1)
LVE: 
103085402(APPL1)
ECB: 
100058653(APPL1)
EPZ: 
103547870(APPL1)
EAI: 
106848655(APPL1)
MYB: 
102250837(APPL1)
MYD: 
102773012(APPL1)
HAI: 
109377590(APPL1)
RSS: 
109443606(APPL1)
PALE: 
102887604(APPL1)
LAV: 
100657434(APPL1)
MDO: 
100010013(APPL1)
SHR: 
100921499(APPL1)
OAA: 
100089140(APPL1)
GGA: 
416002(APPL1)
MGP: 
100547896(APPL1)
CJO: 
107319769(APPL1)
APLA: 
101798507(APPL1)
ACYG: 
106040513(APPL1)
TGU: 
100226921(APPL1)
GFR: 
102036365(APPL1)
FAB: 
101818861(APPL1)
PHI: 
102101270(APPL1)
PMAJ: 
107210342(APPL1)
CCW: 
104683267(APPL1)
FPG: 
101918142(APPL1)
FCH: 
102055056(APPL1)
CLV: 
102087711(APPL1)
AAM: 
106495171(APPL1)
ASN: 
102384706(APPL1)
AMJ: 
102573987(APPL1)
PSS: 
102457050(APPL1)
CMY: 
102937117(APPL1)
CPIC: 
101950184(APPL1)
ACS: 
100564640(appl1)
PVT: 
110082404(APPL1)
PBI: 
103061921(APPL1)
GJA: 
107107451(APPL1)
XLA: 
398493(appl1.S) 398984(appl1.L)
XTR: 
100038055(appl1)
NPR: 
108786881(APPL1)
DRE: 
571540(appl1)
SRX: 
SANH: 
SGH: 
107557417(appl1)
IPU: 
108254880(appl1)
AMEX: 
103038259(appl1)
TRU: 
101078952(appl1)
TNG: 
LCO: 
104940242(appl1)
NCC: 
MZE: 
101469918(appl1)
OLA: 
101169445(appl1)
XMA: 
CSEM: 
103386656(appl1)
LCF: 
108874777(appl1)
HCQ: 
109521490(appl1)
BPEC: 
110157714(appl1)
SASA: 
ELS: 
105017453(appl1)
SFM: 
108936613(appl1)
LCM: 
102354094(APPL1)
CMK: 
103176777(appl1)
BFO: 
CIN: 
SPU: 
SKO: 
ISC: 
TSP: 
LGI: 
CRG: 
OBI: 
LAK: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Miaczynska M, Christoforidis S, Giner A, Shevchenko A, Uttenweiler-Joseph S, Habermann B, Wilm M, Parton RG, Zerial M
  Title
APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment.
  Journal
Cell 116:445-56 (2004)
DOI:10.1016/S0092-8674(04)00117-5
  Sequence
[hsa:26060]

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