KEGG   ORTHOLOGY: K17685
Entry
K17685                      KO                                     
Symbol
CYP2A13
Name
cytochrome P450 family 2 subfamily A13 [EC:1.14.14.1]
Pathway
map00980  Metabolism of xenobiotics by cytochrome P450
map05204  Chemical carcinogenesis - DNA adducts
Reaction
R09406  
R09408  
R09421  
R09423  
R09424  
R09425  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K17685  CYP2A13; cytochrome P450 family 2 subfamily A13
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K17685  CYP2A13; cytochrome P450 family 2 subfamily A13
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17685  CYP2A13; cytochrome P450 family 2 subfamily A13
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K17685  CYP2A13; cytochrome P450 family 2 subfamily A13
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K17685  CYP2A13; cytochrome P450 family 2 subfamily A13
Genes
HSA: 1553(CYP2A13)
PTR: 101058187
PPS: 100982833(CYP2A13)
GGO: 101127384
PON: 100458875
NLE: 100579248 115830830
HMH: 116480658
MCC: 114674219 678689(CYP2A24) 678690(CYP2A23) 702954(CYP2A26) 722086
MCF: 102121341(CYP2A26) 102123758(CYP2A23) 102143277(CYP2A13)
MTHB: 126942025 126942026 126942027
PTEH: 111554024
CJC: 100399054(CYP2A7)
SBQ: 101046499
CIMI: 108285671(CYP2A6)
LCAT: 123624295
PCOQ: 105820478
PKL: 118730245
TOD: 119250434
CTIG: 120316367
APRI: 131204543
HCG: 128332693
STOW: 125424829
DPOL: 127863877
 » show all
Reference
  Authors
Su T, Bao Z, Zhang QY, Smith TJ, Hong JY, Ding X
  Title
Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
  Journal
Cancer Res 60:5074-9 (2000)
  Sequence
[hsa:1553]

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