KEGG   PATHWAY: ko00052Help
Entry
ko00052                     Pathway                                

Name
Galactose metabolism
Class
Metabolism; Carbohydrate metabolism
BRITE hierarchy
Pathway map
ko00052  Galactose metabolism
ko00052

Ortholog table
Module
M00277  PTS system, N-acetylgalactosamine-specific II component [PATH:ko00052]
M00279  PTS system, galactitol-specific II component [PATH:ko00052]
M00281  PTS system, lactose-specific II component [PATH:ko00052]
M00287  PTS system, galactosamine-specific II component [PATH:ko00052]
M00309  Non-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate [PATH:ko00052]
M00552  D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:ko00052]
M00554  Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:ko00052]
M00632  Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:ko00052]
M00633  Semi-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate-3P [PATH:ko00052]
Disease
H00070  Galactosemia
H00116  Congenital lactase deficiency
H01940  Glycogen storage disease type II
H02008  Galactose-1P uridylyltransferase deficiency
H02009  Galactokinase deficiency
H02010  Galactose epimerase deficiency
Other DBs
BSID: 292
GO: 0006012
Orthology
K01785  aldose 1-epimerase [EC:5.1.3.3]
K00849  galactokinase [EC:2.7.1.6]
K00965  UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
K01784  UDP-glucose 4-epimerase [EC:5.1.3.2]
K17716  UDP-glucose 4-epimerase [EC:5.1.3.2]
K00963  UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
K01835  phosphoglucomutase [EC:5.4.2.2]
K15778  phosphomannomutase / phosphoglucomutase [EC:5.4.2.2 5.4.2.8]
K15779  phosphoglucomutase / phosphopentomutase [EC:5.4.2.7 5.4.2.2]
K00844  hexokinase [EC:2.7.1.1]
K12407  glucokinase [EC:2.7.1.2]
K00845  glucokinase [EC:2.7.1.2]
K01084  glucose-6-phosphatase [EC:3.1.3.9]
K01190  beta-galactosidase [EC:3.2.1.23]
K12111  evolved beta-galactosidase subunit alpha [EC:3.2.1.23]
K12112  evolved beta-galactosidase subunit beta
K12308  beta-galactosidase [EC:3.2.1.23]
K12309  beta-galactosidase [EC:3.2.1.23]
K01229  lactase-phlorizin hydrolase [EC:3.2.1.62 3.2.1.108]
K00704  alpha-lactalbumin [EC:2.4.1.22]
K07966  beta-1,4-galactosyltransferase 1 [EC:2.4.1.- 2.4.1.38 2.4.1.90 2.4.1.22]
K07967  beta-1,4-galactosyltransferase 2 [EC:2.4.1.- 2.4.1.38 2.4.1.90 2.4.1.22]
K12447  UDP-sugar pyrophosphorylase [EC:2.7.7.64]
K01854  UDP-galactopyranose mutase [EC:5.4.99.9]
K18819  inositol 3-alpha-galactosyltransferase [EC:2.4.1.123]
K06617  raffinose synthase [EC:2.4.1.82]
K01189  alpha-galactosidase [EC:3.2.1.22]
K07406  alpha-galactosidase [EC:3.2.1.22]
K07407  alpha-galactosidase [EC:3.2.1.22]
K00011  aldehyde reductase [EC:1.1.1.21]
K02773  PTS system, galactitol-specific IIA component [EC:2.7.1.200]
K02774  PTS system, galactitol-specific IIB component [EC:2.7.1.200]
K02775  PTS system, galactitol-specific IIC component
K00094  galactitol-1-phosphate 5-dehydrogenase [EC:1.1.1.251]
K21620  galactitol 2-dehydrogenase [EC:1.1.1.16]
K21621  tagatose kinase [EC:2.7.1.101]
K21622  D-tagatose 6-phosphate 4-epimerase [EC:5.1.3.40]
K00917  tagatose 6-phosphate kinase [EC:2.7.1.144]
K00850  6-phosphofructokinase 1 [EC:2.7.1.11]
K16370  6-phosphofructokinase 2 [EC:2.7.1.11]
K21071  ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.90 2.7.1.11]
K01635  tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]
K08302  tagatose 1,6-diphosphate aldolase GatY/KbaY [EC:4.1.2.40]
K16371  D-tagatose-1,6-bisphosphate aldolase subunit GatZ/KbaZ
K00035  D-galactose 1-dehydrogenase [EC:1.1.1.48]
K22215  galactose dehydrogenase [EC:1.1.1.120 1.1.1.48]
K18124  glucose/galactose 1-dehydrogenase (NADP+) [EC:1.1.1.360]
K18125  aldose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.359]
K04618  galactose oxidase [EC:1.1.3.9]
K01684  galactonate dehydratase [EC:4.2.1.6]
K05308  gluconate/galactonate dehydratase [EC:4.2.1.140]
K11395  2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase [EC:4.1.2.55]
K18127  2-dehydro-3-deoxy-D-gluconate aldolase [EC:4.1.2.51]
K00883  2-dehydro-3-deoxygalactonokinase [EC:2.7.1.58]
K18126  2-dehydro-3-deoxygluconokinase / 2-dehydro-3-deoxygalactonokinase [EC:2.7.1.178]
K01631  2-dehydro-3-deoxyphosphogalactonate aldolase [EC:4.1.2.21]
K01819  galactose-6-phosphate isomerase [EC:5.3.1.26]
K01220  6-phospho-beta-galactosidase [EC:3.2.1.85]
K02786  PTS system, lactose-specific IIA component [EC:2.7.1.207]
K02787  PTS system, lactose-specific IIB component [EC:2.7.1.207]
K02788  PTS system, lactose-specific IIC component
K01193  beta-fructofuranosidase [EC:3.2.1.26]
K06611  stachyose synthetase [EC:2.4.1.67]
K12047  maltase-glucoamylase [EC:3.2.1.3 3.2.1.20]
K01187  alpha-glucosidase [EC:3.2.1.20]
K12316  lysosomal alpha-glucosidase [EC:3.2.1.20]
K12317  neutral alpha-glucosidase C [EC:3.2.1.20]
K01182  oligo-1,6-glucosidase [EC:3.2.1.10]
K01203  sucrase-isomaltase [EC:3.2.1.10 3.2.1.48]
K02744  PTS system, N-acetylgalactosamine-specific IIA component [EC:2.7.1.-]
K02745  PTS system, N-acetylgalactosamine-specific IIB component [EC:2.7.1.-]
K02746  PTS system, N-acetylgalactosamine-specific IIC component
K02747  PTS system, N-acetylgalactosamine-specific IID component
K02079  N-acetylgalactosamine-6-phosphate deacetylase [EC:3.5.1.25]
K02080  galactosamine-6-phosphate isomerase [EC:5.3.1.-]
K10984  PTS system, galactosamine-specific IIB component [EC:2.7.1.-]
K10985  PTS system, galactosamine-specific IIC component
K10986  PTS system, galactosamine-specific IID component
Compound
C00029  UDP-glucose
C00031  D-Glucose
C00052  UDP-alpha-D-galactose
C00085  D-Fructose 6-phosphate
C00089  Sucrose
C00095  D-Fructose
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00116  Glycerol
C00118  D-Glyceraldehyde 3-phosphate
C00124  D-Galactose
C00137  myo-Inositol
C00159  D-Mannose
C00243  Lactose
C00267  alpha-D-Glucose
C00446  alpha-D-Galactose 1-phosphate
C00492  Raffinose
C00577  D-Glyceraldehyde
C00668  alpha-D-Glucose 6-phosphate
C00794  D-Sorbitol
C00795  D-Tagatose
C00880  D-Galactonate
C00984  alpha-D-Galactose
C01097  D-Tagatose 6-phosphate
C01113  D-Galactose 6-phosphate
C01132  N-Acetyl-D-galactosamine
C01216  2-Dehydro-3-deoxy-D-galactonate
C01235  alpha-D-Galactosyl-(1->3)-1D-myo-inositol
C01286  2-Dehydro-3-deoxy-6-phospho-D-galactonate
C01613  Stachyose
C01697  Galactitol
C02262  D-Galactosamine
C02669  D-Galactono-1,5-lactone
C03383  D-Galactono-1,4-lactone
C03733  UDP-alpha-D-galactofuranose
C03785  D-Tagatose 1,6-bisphosphate
C05396  Lactose 6'-phosphate
C05399  Melibiitol
C05400  Epimelibiose
C05401  3-beta-D-Galactosyl-sn-glycerol
C05402  Melibiose
C05404  D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose
C05796  Galactan
C06311  Galactitol 1-phosphate
C06376  N-Acetyl-D-galactosamine 6-phosphate
C06377  D-Galactosamine 6-phosphate

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