KEGG PATHWAY: ko00071

PATHWAY: ko00071

Entry

ko00071 Pathway

Name

Fatty acid metabolism

Class

Metabolism; Lipid metabolism

Pathway map

ko00071

Fatty acid metabolism

Module

M00086	beta-Oxidation, acyl-CoA synthesis [PATH:ko00071]
M00087	beta-Oxidation [PATH:ko00071]

Disease

H00162	Sjogren-Larsson syndrome
H00178	Glutaric acidemia
H00407	Peroxisomal beta-oxidation enzyme deficiency
H00525	Disorders of fatty-acid oxidation
H01267	Familial hyperinsulinemic hypoglycemia (HHF)

Orthology

K00626	acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00632	acetyl-CoA acyltransferase [EC:2.3.1.16]
K07513	acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
K07508	acetyl-CoA acyltransferase 2 [EC:2.3.1.16]
K07509	acetyl-CoA acyltransferase [EC:2.3.1.16]
K01825	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:5.3.3.8 5.1.2.3 4.2.1.17 1.1.1.35]
K01782	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:5.1.2.3 4.2.1.17 1.1.1.35]
K00022	3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K07515	enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.211 4.2.1.17]
K10527	enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.211 1.1.1.35 4.2.1.17]
K01692	enoyl-CoA hydratase [EC:4.2.1.17]
K07514	enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8 1.1.1.35 4.2.1.17]
K07511	enoyl-CoA hydratase [EC:4.2.1.17]
K07516	3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K13767	enoyl-CoA hydratase [EC:4.2.1.17]
K00232	acyl-CoA oxidase [EC:1.3.3.6]
K00248	butyryl-CoA dehydrogenase [EC:1.3.8.1]
K00249	acyl-CoA dehydrogenase [EC:1.3.8.7]
K00255	long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]
K06445	acyl-CoA dehydrogenase [EC:1.3.99.-]
K09478	short/branched chain acyl-CoA dehydrogenase [EC:1.3.99.12]
K09479	very long chain acyl-CoA dehydrogenase [EC:1.3.8.9]
K00252	glutaryl-CoA dehydrogenase [EC:1.3.8.6]
K01897	long-chain acyl-CoA synthetase [EC:6.2.1.3]
K15013	long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K08765	carnitine O-palmitoyltransferase 1 [EC:2.3.1.21]
K08766	carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K01909	long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:6.2.1.20]
K05939	acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:6.2.1.20 2.3.1.40]
K13238	3,2-trans-enoyl-CoA isomerase, mitochondrial [EC:5.3.3.8]
K13239	peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8]
K00496	alkane 1-monooxygenase [EC:1.14.15.3]
K07425	cytochrome P450, family 4, subfamily A [EC:1.14.15.3]
K00529	ferredoxin--NAD+ reductase [EC:1.18.1.3]
K14581	naphthalene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component [EC:1.18.1.3]
K05297	rubredoxin-NAD+ reductase [EC:1.18.1.1]
K13951	alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980	alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121	S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.1 1.1.1.284]
K13952	alcohol dehydrogenase 6 [EC:1.1.1.1]
K04072	acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.1.1.1 1.2.1.10]
K13953	alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
K13954	alcohol dehydrogenase [EC:1.1.1.1]
K00001	alcohol dehydrogenase [EC:1.1.1.1]
K00128	aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K14085	aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.3 1.2.1.8 1.2.1.31]
K00149	aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.3 1.2.1.47]
K00493	unspecific monooxygenase [EC:1.14.14.1]
K14338	cytochrome P450 / NADPH-cytochrome P450 reductase [EC:1.6.2.4 1.14.14.1]

Compound

C00010	CoA
C00024	Acetyl-CoA
C00071	Aldehyde
C00136	Butanoyl-CoA
C00154	Palmitoyl-CoA
C00162	Fatty acid
C00173	Acyl-[acyl-carrier protein]
C00226	Primary alcohol
C00229	Acyl-carrier protein
C00249	Hexadecanoic acid
C00332	Acetoacetyl-CoA
C00340	Reduced rubredoxin
C00435	Oxidized rubredoxin
C00489	Glutarate
C00517	Hexadecanal
C00527	Glutaryl-CoA
C00638	Long-chain fatty acid
C00823	1-Hexadecanol
C00877	Crotonoyl-CoA
C01144	(S)-3-Hydroxybutanoyl-CoA
C01371	Alkane
C01832	Lauroyl-CoA
C01944	Octanoyl-CoA
C02593	Tetradecanoyl-CoA
C02990	L-Palmitoylcarnitine
C03221	2-trans-Dodecenoyl-CoA
C03547	omega-Hydroxy fatty acid
C03561	(R)-3-Hydroxybutanoyl-CoA
C05102	alpha-Hydroxy fatty acid
C05258	(S)-3-Hydroxyhexadecanoyl-CoA
C05259	3-Oxopalmitoyl-CoA
C05260	(S)-3-Hydroxytetradecanoyl-CoA
C05261	3-Oxotetradecanoyl-CoA
C05262	(S)-3-Hydroxydodecanoyl-CoA
C05263	3-Oxododecanoyl-CoA
C05264	(S)-Hydroxydecanoyl-CoA
C05265	3-Oxodecanoyl-CoA
C05266	(S)-3-Hydroxyoctanoyl-CoA
C05267	3-Oxooctanoyl-CoA
C05268	(S)-Hydroxyhexanoyl-CoA
C05269	3-Oxohexanoyl-CoA
C05270	Hexanoyl-CoA
C05271	trans-Hex-2-enoyl-CoA
C05272	trans-Hexadec-2-enoyl-CoA
C05273	trans-Tetradec-2-enoyl-CoA
C05274	Decanoyl-CoA
C05275	trans-Dec-2-enoyl-CoA
C05276	trans-Oct-2-enoyl-CoA
C05279	trans,cis-Lauro-2,6-dienoyl-CoA
C05280	cis,cis-3,6-Dodecadienoyl-CoA

Reference

PMID:869535

Authors

Parekh VR, Traxler RW, Sobek JM

Title

N-Alkane oxidation enzymes of a pseudomonad.

Journal

Appl Environ Microbiol 33:881-4 (1977)

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (7)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
   BioSystems (1)   
Disease (5)   
   KEGG DISEASE (5)   
Chemical substance (50)   
   KEGG COMPOUND (50)   
Chemical reaction (31)   
   KEGG ENZYME (31)   
Gene (49)   
   KEGG ORTHOLOGY (49)   
Literature (1)   
   PubMed (1)   
All databases (144)   

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