KEGG   PATHWAY: ko00562Help
Entry
ko00562                     Pathway                                

Name
Inositol phosphate metabolism
Class
Metabolism; Carbohydrate metabolism
BRITE hierarchy
Pathway map
Inositol phosphate metabolism
ko00562

All organismsOrtholog table
Module
M00130  
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:ko00562]
M00131  
Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:ko00562]
M00132  
Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:ko00562]
Disease
H00530  
Joubert syndrome
H00692  
Lowe syndrome
H00694  
Dent disease
H00700  
Centronuclear myopathy
H00865  
Lethal congenital contractural syndrome (LCCS)
H00957  
Fleck corneal dystrophy (FCD)
H01195  
VACTERL/VATER association
H01387  
Activated PI3K-delta syndrome (APDS)
Other DBs
BSID: 
GO: 
Orthology
K00914  
phosphatidylinositol 3-kinase [EC:2.7.1.137]
K01108  
phosphatidylinositol-3-phosphatase [EC:3.1.3.64]
K00888  
phosphatidylinositol 4-kinase [EC:2.7.1.67]
K13711  
phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
K00889  
1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K13712  
phosphatidylinositol-4-phosphate 5-kinase-like protein 1 [EC:2.7.1.68]
K01099  
phosphatidylinositol-bisphosphatase [EC:3.1.3.36]
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05857  
phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05860  
phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859  
phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05861  
phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K01110  
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.67 3.1.3.48 3.1.3.16]
K00920  
1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K03084  
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K15909  
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K00923  
phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
K01109  
inositol polyphosphate-4-phosphatase [EC:3.1.3.66]
K00921  
1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
K01114  
phospholipase C [EC:3.1.4.3]
K16619  
phospholipase C / alpha-toxin [EC:3.1.4.3]
K01771  
1-phosphatidylinositol phosphodiesterase [EC:4.6.1.13]
K01092  
myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
K10047  
inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase [EC:3.1.3.- 3.1.3.25]
K15759  
inositol monophosphatase 3 [EC:3.1.3.7 3.1.3.25]
K00999  
CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11]
K01858  
myo-inositol-1-phosphate synthase [EC:5.5.1.4]
K01107  
inositol polyphosphate 1-phosphatase [EC:3.1.3.57]
K15422  
3'(2'), 5'-bisphosphate nucleotidase / inositol polyphosphate 1-phosphatase [EC:3.1.3.57 3.1.3.7]
K01106  
inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]
K03103  
multiple inositol-polyphosphate phosphatase [EC:3.1.3.62]
K00911  
1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]
K00913  
inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.134 2.7.1.159]
K00915  
1D-myo-Inositol-tetrakisphosphate 5-kinase / inositol-polyphosphate multikinase [EC:2.7.1.151 2.7.1.140]
K00328  
inositol-polyphosphate multikinase [EC:2.7.1.151]
K10572  
inositol-pentakisphosphate 2-kinase [EC:2.7.1.158]
K01083  
3-phytase [EC:3.1.3.8]
K01093  
4-phytase / acid phosphatase [EC:3.1.3.2 3.1.3.26]
K07281  
1L-myo-inositol 1-phosphate cytidylyltransferase [EC:2.7.7.74]
K07291  
CDP-L-myo-inositol myo-inositolphosphotransferase [EC:2.7.8.34]
K00469  
inositol oxygenase [EC:1.13.99.1]
K00010  
myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.369 1.1.1.18]
K06606  
2-keto-myo-inositol isomerase [EC:5.3.99.11]
K16043  
scyllo-inositol 2-dehydrogenase (NAD+) [EC:1.1.1.370]
K16044  
scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.371]
K03335  
inosose dehydratase [EC:4.2.1.44]
K03336  
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) [EC:3.7.1.22]
K03337  
5-deoxy-glucuronate isomerase [EC:5.3.1.30]
K03338  
5-dehydro-2-deoxygluconokinase [EC:2.7.1.92]
K03339  
6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase [EC:4.1.2.29]
K00140  
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.27 1.2.1.18]
K01803  
triosephosphate isomerase (TIM) [EC:5.3.1.1]
Compound
C00024  
Acetyl-CoA
C00092  
D-Glucose 6-phosphate
C00111  
Glycerone phosphate
C00118  
D-Glyceraldehyde 3-phosphate
C00137  
myo-Inositol
C00191  
D-Glucuronate
C00222  
3-Oxopropanoate
C00641  
1,2-Diacyl-sn-glycerol
C00691  
2,4,6/3,5-Pentahydroxycyclohexanone
C01177  
Inositol 1-phosphate
C01194  
1-Phosphatidyl-D-myo-inositol
C01204  
Phytic acid
C01220  
1D-myo-Inositol 1,4-bisphosphate
C01243  
1D-myo-Inositol 1,3,4-trisphosphate
C01245  
D-myo-Inositol 1,4,5-trisphosphate
C01272  
1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  
1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  
1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  
myo-Inositol 4-phosphate
C03659  
1-O-Methyl-myo-inositol
C03660  
3-O-Methyl-myo-inositol
C04006  
1D-myo-Inositol 3-phosphate
C04062  
D-myo-Inositol 1,3-bisphosphate
C04063  
D-myo-Inositol 3,4-bisphosphate
C04287  
3D-(3,5/4)-Trihydroxycyclohexane-1,2-dione
C04477  
1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04520  
1D-myo-Inositol 3,4,5,6-tetrakisphosphate
C04549  
1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04563  
D-myo-Inositol 1,2,4,5,6-pentakisphosphate
C04579  
Inositol 1,2,3,5,6-pentakisphosphate
C04637  
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  
Phosphatidylinositol-3,4,5-trisphosphate
C06153  
scyllo-Inositol
C06892  
2-Deoxy-5-keto-D-gluconic acid
C06893  
2-Deoxy-5-keto-D-gluconic acid 6-phosphate
C11554  
1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  
1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  
1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  
1-Phosphatidyl-1D-myo-inositol 5-phosphate
C16737  
5-Deoxy-D-glucuronate
C19794  
CDP-1L-myo-inositol
C19799  
Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
C19891  
1D-chiro-Inositol
C20251  
1-Keto-D-chiro-inositol
Reference
  Authors
Yoshida K, Yamaguchi M, Ikeda H, Omae K, Tsurusaki K, Fujita Y
  Title
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
  Journal
Microbiology 150:571-80 (2004)
Reference
  Authors
Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y.
  Title
myo-Inositol catabolism in Bacillus subtilis.
  Journal
J Biol Chem 283:10415-24 (2008)

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