KEGG   PATHWAY: ko00670Help
Entry
ko00670                     Pathway                                

Name
One carbon pool by folate
Class
Metabolism; Metabolism of cofactors and vitamins
BRITE hierarchy
Pathway map
One carbon pool by folate
ko00670

All organismsOrtholog table
Module
M00126  
Tetrahydrofolate biosynthesis, GTP => THF [PATH:ko00670]
M00140  
C1-unit interconversion, prokaryotes [PATH:ko00670]
M00141  
C1-unit interconversion, eukaryotes [PATH:ko00670]
Disease
H00183  
Homocystinuria
H00262  
Spina bifida
H00966  
AICA-ribosiduria
H01197  
Dihydrofolate reductase (DHFR) deficiency
H01262  
Formiminotransferase deficiency
H01285  
Methylcobalamin deficiency type G (cblG)
Drug
D00145  
Trimethoprim (JAN/USP/INN)
D00488  
Pyrimethamine (JAN/USP/INN)
D02487  
Proguanil hydrochloride (JAN)
D03771  
Diaveridine (USAN/INN)
D06236  
Trimethoprim sulfate (USP)
D08337  
Iclaprim (USAN/INN)
D08428  
Proguanil (INN)
D08563  
Iclaprim mesylate (USAN)
D08644  
Trimethoprim lactate
Orthology
K00287  
dihydrofolate reductase [EC:1.5.1.3]
K18589  
dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18590  
dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18591  
dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K13998  
dihydrofolate reductase / thymidylate synthase [EC:2.1.1.45 1.5.1.3]
K13938  
dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.3 1.5.1.-]
K01938  
formate--tetrahydrofolate ligase [EC:6.3.4.3]
K13402  
monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]
K00288  
methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:6.3.4.3 3.5.4.9 1.5.1.5]
K01491  
methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9 1.5.1.5]
K13403  
methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9 1.5.1.15]
K00295  
methylenetetrahydrofolate dehydrogenase (NAD+) [EC:1.5.1.15]
K00600  
glycine hydroxymethyltransferase [EC:2.1.2.1]
K11787  
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1 2.1.2.2 6.3.4.13]
K00601  
phosphoribosylglycinamide formyltransferase [EC:2.1.2.2]
K11175  
phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
K08289  
phosphoribosylglycinamide formyltransferase 2 [EC:2.1.2.2]
K00602  
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:3.5.4.10 2.1.2.3]
K00603  
glutamate formiminotransferase [EC:2.1.2.5]
K13990  
glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:4.3.1.4 2.1.2.5]
K00604  
methionyl-tRNA formyltransferase [EC:2.1.2.9]
K00605  
aminomethyltransferase [EC:2.1.2.10]
K00548  
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
K00560  
thymidylate synthase [EC:2.1.1.45]
K03465  
thymidylate synthase (FAD) [EC:2.1.1.148]
K00289  
formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]
K01433  
formyltetrahydrofolate deformylase [EC:3.5.1.10]
K00297  
methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]
K01746  
formiminotetrahydrofolate cyclodeaminase [EC:4.3.1.4]
K01934  
5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
Compound
C00101  
Tetrahydrofolate
C00143  
5,10-Methylenetetrahydrofolate
C00234  
10-Formyltetrahydrofolate
C00415  
Dihydrofolate
C00440  
5-Methyltetrahydrofolate
C00445  
5,10-Methenyltetrahydrofolate
C00504  
Folate
C00664  
5-Formiminotetrahydrofolate
C03479  
Folinic acid

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