| Entry |
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| Name |
Acridone alkaloid biosynthesis
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| Description |
Acridone alkaloids are anthranillic acid-derived plant alkaloids found in Rutaceae (rue family). Compounds in this class have been tested for antitumor and antimicrobial activities.
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| Class |
Metabolism; Biosynthesis of other secondary metabolites
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| Pathway map |
| Acridone alkaloid biosynthesis |
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| Orthology |
| anthranilate N-methyltransferase [EC: 2.1.1.111] | | |
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| Compound |
| Anthranilate | | N-Methylanthranilate | | Acronycine | | Melicopicine | | Rutacridone | | N-Methylanthraniloyl-CoA | | 1,3-Dihydroxy-N-methylacridone |
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| Reference |
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| Authors |
Funayama S. |
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| Title |
[Arukaroido -Doku to Kusuri no Houko-] (In Japanese) |
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| Journal |
Kyouritu shuppan kabusikikaisya:183-187 (1998) |
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| Reference |
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| Authors |
Paul M Dewick. |
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| Title |
Medicinal Natural Products -A Biosynthetic Approach- (2nd ed) |
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| Journal |
John Wiley and Sons, LTD:376-379 (2001) |
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| Reference |
|
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| Authors |
Jeffrey B, Herbert B, Gerard P. |
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| Title |
Phytochemical Dictionary-A Handbook of Bioactive Compounds from Plants (2nd ed) |
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| Journal |
Taylor and Francis:301-316 (1999) |
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| Reference |
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| Authors |
Lukacin R, Springob K, Urbanke C, Ernwein C, Schroder G, Schroder J, Matern U. |
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| Title |
Native acridone synthases I and II from Ruta graveolens L. form homodimers |
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| Journal |
FEBS Lett 448:135-40 (1999) |
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