Entry
Name
Pathways in cancer
Class
Human Diseases; Cancer: overview
BRITE hierarchy
Pathway map
Ortholog table
Orthology
K06765 deleted in colorectal carcinoma
K08733 DCC-interacting protein 13 alpha
K05689 cadherin 1, type 1, E-cadherin
K02085 adenomatosis polyposis coli protein
K04490 transcription factor 7-like 1
K04491 transcription factor 7-like 2
K04492 lymphoid enhancer-binding factor 1
K08731 baculoviral IAP repeat-containing protein 5
K04377 Myc proto-oncogene protein
K04503 G1/S-specific cyclin-D1
K03209 wingless-type MMTV integration site family, member 1
K00182 wingless-type MMTV integration site family, member 2
K00312 wingless-type MMTV integration site family, member 3
K00408 wingless-type MMTV integration site family, member 4
K00444 wingless-type MMTV integration site family, member 5
K00445 wingless-type MMTV integration site family, member 6
K00572 wingless-type MMTV integration site family, member 7
K00714 wingless-type MMTV integration site family, member 8
K01064 wingless-type MMTV integration site family, member 9
K01357 wingless-type MMTV integration site family, member 10
K01384 wingless-type MMTV integration site family, member 11
K01558 wingless-type MMTV integration site family, member 16
K03068 low density lipoprotein receptor-related protein 5/6
K02353 segment polarity protein dishevelled
K03069 frequently rearranged in advanced T-cell lymphomas 1
K03096 frequently rearranged in advanced T-cell lymphomas 2
K03914 coagulation factor II (thrombin) receptor
K04236 coagulation factor II (thrombin) receptor-like 3
K04289 lysophosphatidic acid receptor 1
K04291 lysophosphatidic acid receptor 2
K04294 lysophosphatidic acid receptor 3
K04275 lysophosphatidic acid receptor 4
K08390 lysophosphatidic acid receptor 5
K04273 lysophosphatidic acid receptor 6
K04166 angiotensin II receptor type 1
K04346 guanine nucleotide-binding protein subunit alpha-12
K04639 guanine nucleotide-binding protein subunit alpha-13
K07532 Rho guanine nucleotide exchange factor 12
K12331 Rho guanine nucleotide exchange factor 11
K12330 Rho guanine nucleotide exchange factor 1
K19464 pleckstrin homology domain-containing family G member 5
K04513 Ras homolog gene family, member A
K10031 C-X-C motif chemokine 12
K04189 C-X-C chemokine receptor type 4
K04630 guanine nucleotide-binding protein G(i) subunit alpha
K04258 prostaglandin E receptor 1
K04259 prostaglandin E receptor 2
K04260 prostaglandin E receptor 3
K04261 prostaglandin E receptor 4
K04632 guanine nucleotide-binding protein G(s) subunit alpha
K04536 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 guanine nucleotide-binding protein subunit beta-4
K04539 guanine nucleotide-binding protein subunit beta-5
K07826 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K00922 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153 ]
K02649 phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K09348 homeobox protein Nkx-3.1
K04467 inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10 ]
K07209 inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10 ]
K07210 inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NF-kappa-B inhibitor alpha
K02580 nuclear factor NF-kappa-B p105 subunit
K04469 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 transcription factor p65
K02161 apoptosis regulator Bcl-2
K16060 baculoviral IAP repeat-containing protein 2/3
K16061 baculoviral IAP repeat-containing protein 7/8
K04570 Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TNF receptor-associated factor 1
K03174 TNF receptor-associated factor 3
K09848 TNF receptor-associated factor 4
K09849 TNF receptor-associated factor 5
K02158 Bcl-2-antagonist of cell death
K07201 forkhead box protein O1
K06624 cyclin-dependent kinase inhibitor 1B
K06625 cyclin-dependent kinase inhibitor 1A
K04438 C-crk adapter molecule crk
K11223 signal transducer and activator of transcription 5A
K11224 signal transducer and activator of transcription 5B
K04702 proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1 ]
K08806 proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1 ]
K04197 endothelin receptor type A
K04198 endothelin receptor type B
K04634 guanine nucleotide-binding protein G(q) subunit alpha
K04635 guanine nucleotide-binding protein subunit alpha-11
K05426 interleukin 23 subunit alpha
K05068 interleukin 2 receptor alpha
K05069 interleukin 2 receptor beta
K05070 interleukin 2 receptor gamma
K04737 interleukin 3 receptor alpha
K04738 cytokine receptor common subunit beta
K05067 interleukin 5 receptor alpha
K05060 interleukin 6 signal transducer
K05063 interleukin 12 receptor beta-1
K05064 interleukin 12 receptor beta-2
K05076 interleukin 13 receptor alpha-1
K05074 interleukin 15 receptor alpha
K05065 interleukin 23 receptor
K05079 erythropoietin receptor
K05132 interferon gamma receptor 1
K05133 interferon gamma receptor 2
K15420 echinoderm microtubule-associated protein-like 4
K04350 RAS guanyl-releasing protein 1
K12361 RAS guanyl-releasing protein 2
K12362 RAS guanyl-releasing protein 3
K12363 RAS guanyl-releasing protein 4
K04692 signal transducer and activator of transcription 3
K11220 signal transducer and activator of transcription 1
K11221 signal transducer and activator of transcription 2
K11222 signal transducer and activator of transcription 4
K11225 signal transducer and activator of transcription 6
K05448 vascular endothelial growth factor A
K16858 vascular endothelial growth factor B
K05449 vascular endothelial growth factor C/D
K08774 transforming growth factor, alpha
K04357 epidermal growth factor
K04359 platelet-derived growth factor subunit A
K17386 platelet-derived growth factor subunit B
K05459 insulin-like growth factor 1
K13769 insulin-like growth factor 2
K05454 fms-related tyrosine kinase 3 ligand
K05460 hepatocyte growth factor
K18496 fibroblast growth factor 1
K18497 fibroblast growth factor 2
K04358 fibroblast growth factor
K22603 fibroblast growth factor 19
K22429 fibroblast growth factor 21
K22428 fibroblast growth factor 23
K04364 growth factor receptor-bound protein 2
K08845 A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1 ]
K04365 B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1 ]
K04366 RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1 ]
K04448 transcription factor AP-1
K04379 proto-oncogene protein c-fos
K01388 matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7 ]
K09288 coiled-coil domain-containing protein 6
K09289 nuclear receptor coactivator 4
K09850 Ras association domain-containing protein 1
K08015 Ras association domain-containing protein 5
K04411 serine/threonine kinase 4
K04375 ETS domain-containing protein Elk-1
K04515 calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17 ]
K08732 ral guanine nucleotide dissociation stimulator
K07834 Ras-related protein Ral-A
K07835 Ras-related protein Ral-B
K04393 cell division control protein 42
K04392 Ras-related C3 botulinum toxin substrate 1
K07860 Ras-related C3 botulinum toxin substrate 2
K07861 Ras-related C3 botulinum toxin substrate 3
K04440 mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24 ]
K08530 peroxisome proliferator-activated receptor gamma
K08524 retinoid X receptor alpha
K08525 retinoid X receptor beta
K08526 retinoid X receptor gamma
K08528 retinoic acid receptor beta
K08550 estrogen receptor alpha
K04684 transcription factor Sp1
K04504 peroxisome proliferator-activated receptor delta
K10055 zinc finger and BTB domain-containing protein 16
K08527 retinoic acid receptor alpha
K10054 E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 runt-related transcription factor 1
K10053 CBFA2/RNUX1 translocation partner 1
K09438 transcription factor PU.1
K09055 CCAAT/enhancer binding protein (C/EBP), alpha
K05066 granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 granulocyte colony-stimulating factor receptor
K06621 cyclin-dependent kinase inhibitor 2A
K17454 transcription factor E2F1
K09389 transcription factor E2F2
K06620 transcription factor E2F3
K10500 zinc finger and BTB domain-containing protein 17
K04685 cyclin-dependent kinase inhibitor 2B
K10151 G1/S-specific cyclin-D2
K10152 G1/S-specific cyclin-D3
K02219 cyclin-dependent kinase regulatory subunit CKS1
K03094 S-phase kinase-associated protein 1
K03875 F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06626 G1/S-specific cyclin-E1
K06618 retinoblastoma-associated protein
K04402 growth arrest and DNA-damage-inducible protein
K02159 apoptosis regulator BAX
K14021 Bcl-2 homologous antagonist/killer
K10140 DNA damage-binding protein 2
K22183 telomerase RNA component
K09455 microphthalmia-associated transcription factor
K13375 transforming growth factor beta-1
K13376 transforming growth factor beta-2
K13377 transforming growth factor beta-3
K04500 mothers against decapentaplegic homolog 2
K23605 mothers against decapentaplegic homolog 3
K04501 mothers against decapentaplegic homolog 4
K04462 [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367 ]
K08734 DNA mismatch repair protein MLH1
K08735 DNA mismatch repair protein MSH2
K08736 DNA mismatch repair protein MSH3
K08737 DNA mismatch repair protein MSH6
K08775 breast cancer 2 susceptibility protein
K04482 DNA repair protein RAD51
K04389 tumor necrosis factor ligand superfamily member 6
K04390 tumor necrosis factor receptor superfamily member 6
K02373 FAS-associated death domain protein
K04726 BH3 interacting domain death agonist
K10131 phorbol-12-myristate-13-acetate-induced protein 1
K10132 Bcl-2-binding component 3
K02084 apoptotic protease-activating factor
K05638 nuclear factor erythroid 2-related factor 2
K03871 von Hippel-Lindau disease tumor supressor
K08268 hypoxia-inducible factor 1 alpha
K09095 hypoxia-inducible factor 2 alpha
K09097 aryl hydrocarbon receptor nuclear translocator
K15589 aryl hydrocarbon receptor nuclear translocator 2
K07299 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06054 hairy and enhancer of split 1
K06055 hairy and enhancer of split 5
K09091 hairy and enhancer of split related with YRPW motif
K18806 kinesin family member 7
K16797 zinc finger protein GLI1
K16798 zinc finger protein GLI2
K06230 zinc finger protein GLI3
K21283 bone morphogenetic protein 2
K04662 bone morphogenetic protein 4
K06231 hedgehog interacting protein
K04079 molecular chaperone HtpG
K09487 heat shock protein 90kDa beta
Compound
C00681 1-Acyl-sn-glycerol 3-phosphate
C01245 D-myo-Inositol 1,4,5-trisphosphate
C05981 Phosphatidylinositol-3,4,5-trisphosphate
C16038 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
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ko04060 Cytokine-cytokine receptor interaction