KEGG   ORTHOLOGY: K00071Help
Entry
K00071                      KO                                     

Name
HSD11B2
Definition
corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
Pathway
Steroid hormone biosynthesis
Aldosterone-regulated sodium reabsorption
Module
M00109  
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Disease
H00259  
Apparent mineralocorticoid excess syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K00071  HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2
 Organismal Systems
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K00071  HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2
KEGG pathway modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Sterol biosynthesis
    M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
     K00071  HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-  
     K00071  HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2
BRITE hierarchy
Other DBs
Genes
HSA: 
3291(HSD11B2)
PTR: 
468001(HSD11B2)
PPS: 
100993079(HSD11B2)
GGO: 
101153708(HSD11B2)
PON: 
100443811(HSD11B2)
MCC: 
574396(HSD11B2)
MCF: 
102115494(HSD11B2)
MMU: 
15484(Hsd11b2)
RNO: 
25117(Hsd11b2)
CGE: 
HGL: 
101712460(Hsd11b2)
TUP: 
102494408(HSD11B2)
CFA: 
489758(HSD11B2)
AML: 
FCA: 
100529249(HSD11B2)
BTA: 
282434(HSD11B2)
BOM: 
102284703(HSD11B2)
PHD: 
102318720(HSD11B2)
CHX: 
102183447(HSD11B2)
SSC: 
396948(HSD11B2)
CFR: 
102516692(HSD11B2)
ECB: 
100034124(HSD11B2)
MYB: 
102247970(HSD11B2)
OAA: 
GGA: 
MGP: 
TGU: 
100222854(HSD11B2)
FAB: 
101815475(HSD11B2)
PHI: 
102111344(HSD11B2)
APLA: 
101790751(HSD11B2)
FPG: 
101912301(HSD11B2)
FCH: 
102059634(HSD11B2)
CLV: 
102085620(HSD11B2)
ASN: 
102377421(HSD11B2)
PSS: 
102451930(HSD11B2)
ACS: 
XLA: 
444491(hsd11b2)
XTR: 
100489854(hsd11b2)
DRE: 
334098(hsd11b2)
TRU: 
MZE: 
OLA: 
100125474(hsd11b2)
XMA: 
LCM: 
102360976(HSD11B2)
ZMA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Gong R, Morris DJ, Brem AS
  Title
Variable expression of 11beta Hydroxysteroid dehydrogenase (11beta-HSD) isoforms  in vascular endothelial cells.
  Journal
Steroids 73:1187-96 (2008)

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