KEGG   ORTHOLOGY: K00182Help
Entry
K00182                      KO                                     

Name
WNT2
Definition
wingless-type MMTV integration site family, member 2
Pathway
mTOR signaling pathway
Wnt signaling pathway
Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells
Melanogenesis
Human papillomavirus infection
HTLV-I infection
Pathways in cancer
Proteoglycans in cancer
Basal cell carcinoma
Breast cancer
Module
M00677  
Wnt signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   04390 Hippo signaling pathway
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   04150 mTOR signaling pathway
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 Organismal Systems
  Endocrine system
   04916 Melanogenesis
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05205 Proteoglycans in cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05217 Basal cell carcinoma
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05224 Breast cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
  Infectious diseases
   05166 HTLV-I infection
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05165 Human papillomavirus infection
    K00182  WNT2; wingless-type MMTV integration site family, member 2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00677  Wnt signaling
     K00182  WNT2; wingless-type MMTV integration site family, member 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Morphogens
   K00182  WNT2; wingless-type MMTV integration site family, member 2
BRITE hierarchy
Genes
HSA: 
7472(WNT2) 7482(WNT2B)
PTR: 
457103(WNT2B) 463673(WNT2)
PPS: 
100983371(WNT2B) 100990322(WNT2)
GGO: 
101129834(WNT2B) 101130779(WNT2)
PON: 
100137034(WNT2) 100460815(WNT2B)
NLE: 
100600353(WNT2) 100607954(WNT2B)
MCC: 
704991(WNT2) 705773(WNT2B)
MCF: 
102129174(WNT2) 102130917(WNT2B)
CSAB: 
103224207(WNT2B) 103226775(WNT2)
RRO: 
104658925(WNT2B) 104682628(WNT2)
RBB: 
108526536(WNT2) 108528095(WNT2B)
CJC: 
100395234(WNT2B) 100411308(WNT2)
SBQ: 
101037307(WNT2) 101051098(WNT2B)
MMU: 
22413(Wnt2) 22414(Wnt2b)
RNO: 
114487(Wnt2) 116466(Wnt2b)
CGE: 
100752722(Wnt2) 100761413(Wnt2b)
NGI: 
103734912(Wnt2b) 103737375(Wnt2)
HGL: 
101704935(Wnt2b) 101723565(Wnt2)
CCAN: 
109681721(Wnt2b) 109684416(Wnt2)
OCU: 
100126569(WNT2) 100349847(WNT2B)
TUP: 
102479831(WNT2B) 102483867(WNT2)
CFA: 
483220(WNT2B) 612141(WNT2)
AML: 
100480237(WNT2) 100481665(WNT2B)
UMR: 
103675048(WNT2B) 103676588(WNT2)
FCA: 
101080904(WNT2B) 493672(WNT2)
PTG: 
102954954(WNT2) 102963336(WNT2B)
AJU: 
106969623(WNT2B) 106970665(WNT2)
BTA: 
445420(WNT2B) 493729(WNT2)
BOM: 
102285570(WNT2B) 102288008(WNT2)
BIU: 
109555924(WNT2B) 109557407(WNT2)
PHD: 
102331632(WNT2) 102336367(WNT2B)
CHX: 
102180281(WNT2) 102182009(WNT2B)
OAS: 
100126577(WNT2) 101116782(WNT2B)
SSC: 
100516839(WNT2) 100520560(WNT2B)
CFR: 
102505341(WNT2) 102517871(WNT2B)
CDK: 
105085323(WNT2) 105102049(WNT2B)
BACU: 
103003752(WNT2) 103013943(WNT2B)
LVE: 
103089326(WNT2) 103089709(WNT2B)
ECB: 
100056092(WNT2) 100063931(WNT2B)
EPZ: 
103541803(WNT2B) 103550603(WNT2)
EAI: 
106828591(WNT2B) 106829346(WNT2)
MYB: 
102255951(WNT2B) 102261227(WNT2)
MYD: 
102752980(WNT2) 102765024(WNT2B)
HAI: 
109389334(WNT2) 109391554(WNT2B)
RSS: 
109446725(WNT2B) 109453462(WNT2)
PALE: 
102880959(WNT2B) 102885080(WNT2)
LAV: 
100653551(WNT2B) 100657046(WNT2)
MDO: 
100011991(WNT2) 100033140(WNT2B)
SHR: 
100918306(WNT2) 100918389(WNT2B)
OAA: 
100077640(WNT2) 100087253(WNT2B)
GGA: 
374243(WNT2B) 417769(WNT2)
MGP: 
100545665(WNT2) 100551435(WNT2B)
CJO: 
107309102(WNT2) 107324859(WNT2B)
APLA: 
ACYG: 
106041264(WNT2B) 106042052(WNT2)
TGU: 
100221216(WNT2) 100227493(WNT2B)
GFR: 
102039793(WNT2B) 102040836(WNT2)
FAB: 
101807109(WNT2B) 101821440(WNT2)
PHI: 
102099201(WNT2) 102111953(WNT2B)
PMAJ: 
107204737(WNT2) 107215039(WNT2B)
CCW: 
104692318(WNT2B) 104698447(WNT2)
FPG: 
101916797(WNT2B) 101924187(WNT2)
FCH: 
102050583(WNT2) 102054880(WNT2B)
CLV: 
102085110(WNT2B) 102093378(WNT2)
AAM: 
106485278(WNT2B) 106488127(WNT2)
ASN: 
102377917(WNT2B) 102388685(WNT2)
AMJ: 
102569359(WNT2) 102575620(WNT2B)
PSS: 
102443393(WNT2B) 102448332(WNT2)
CMY: 
102929895(WNT2B) 102936696(WNT2)
CPIC: 
101932483(WNT2) 101949084(WNT2B)
ACS: 
100559857(wnt2b)
PVT: 
110072347(WNT2B)
PBI: 
103048288(WNT2B)
GJA: 
107110304(WNT2B)
XLA: 
XTR: 
100038261(wnt2) 100491761(wnt2b)
NPR: 
108790556(WNT2B) 108802068(WNT2)
DRE: 
359837(wnt2ba) 556087(wnt2bb)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102345664(WNT2) 102352078(WNT2B)
CMK: 
103179360(wnt2) 103182404(wnt2b)
BFO: 
CIN: 
SKO: 
100303493(Wnt2)
DPX: 
NAI: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
ADF: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kawakami Y, Capdevila J, Buscher D, Itoh T, Rodriguez Esteban C, Izpisua Belmonte JC
  Title
WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo.
  Journal
Cell 104:891-900 (2001)
DOI:10.1016/S0092-8674(01)00285-9
  Sequence
[gga:374243]
Reference
PMID:2971536
  Authors
Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS, et al.
  Title
Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless.
  Journal
EMBO J 7:1743-8 (1988)
  Sequence
[hsa:7472]
Reference
PMID:8761309
  Authors
Katoh M, Hirai M, Sugimura T, Terada M
  Title
Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family.
  Journal
Oncogene 13:873-6 (1996)
  Sequence
[hsa:7482]

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