KEGG   ORTHOLOGY: K00182Help
Entry
K00182                      KO                                     

Name
WNT2
Definition
wingless-type MMTV integration site family, member 2
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing's syndrome
ko05165  Human papillomavirus infection
ko05166  HTLV-I infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Module
M00677  Wnt signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   04390 Hippo signaling pathway
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   04150 mTOR signaling pathway
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 Organismal Systems
  Endocrine system
   04916 Melanogenesis
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05205 Proteoglycans in cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05225 Hepatocellular carcinoma
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05226 Gastric cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05217 Basal cell carcinoma
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05224 Breast cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    K00182  WNT2; wingless-type MMTV integration site family, member 2
  Infectious diseases
   05166 HTLV-I infection
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05165 Human papillomavirus infection
    K00182  WNT2; wingless-type MMTV integration site family, member 2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00677  Wnt signaling
     K00182  WNT2; wingless-type MMTV integration site family, member 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Morphogens
   K00182  WNT2; wingless-type MMTV integration site family, member 2
BRITE hierarchy
Genes
HSA: 7472(WNT2) 7482(WNT2B)
PTR: 457103(WNT2B) 463673(WNT2)
PPS: 100983371(WNT2B) 100990322(WNT2)
GGO: 101129834(WNT2B) 101130779(WNT2)
PON: 100137034(WNT2) 100460815(WNT2B)
NLE: 100600353(WNT2) 100607954(WNT2B)
MCC: 704991(WNT2) 705773(WNT2B)
MCF: 102129174(WNT2) 102130917(WNT2B)
CSAB: 103224207(WNT2B) 103226775(WNT2)
RRO: 104658925(WNT2B) 104682628(WNT2)
RBB: 108526536(WNT2) 108528095(WNT2B)
CJC: 100395234(WNT2B) 100411308(WNT2)
SBQ: 101037307(WNT2) 101051098(WNT2B)
MMU: 22413(Wnt2) 22414(Wnt2b)
RNO: 114487(Wnt2) 116466(Wnt2b)
CGE: 100752722(Wnt2) 100761413(Wnt2b)
NGI: 103734912(Wnt2b) 103737375(Wnt2)
HGL: 101704935(Wnt2b) 101723565(Wnt2)
CCAN: 109681721(Wnt2b) 109684416(Wnt2)
OCU: 100126569(WNT2) 100349847(WNT2B)
TUP: 102479831(WNT2B) 102483867(WNT2)
CFA: 483220(WNT2B) 612141(WNT2)
AML: 100480237(WNT2) 100481665(WNT2B)
UMR: 103675048(WNT2B) 103676588(WNT2)
ORO: 101364222(WNT2) 101373643(WNT2B)
FCA: 101080904(WNT2B) 493672(WNT2)
PTG: 102954954(WNT2) 102963336(WNT2B)
AJU: 106969623(WNT2B) 106970665(WNT2)
BTA: 445420(WNT2B) 493729(WNT2)
BOM: 102285570(WNT2B) 102288008(WNT2)
BIU: 109555924(WNT2B) 109557407(WNT2)
PHD: 102331632(WNT2) 102336367(WNT2B)
CHX: 102180281(WNT2) 102182009(WNT2B)
OAS: 100126577(WNT2) 101116782(WNT2B)
SSC: 100516839(WNT2) 100520560(WNT2B)
CFR: 102505341(WNT2) 102517871(WNT2B)
CDK: 105085323(WNT2) 105102049(WNT2B)
BACU: 103003752(WNT2) 103013943(WNT2B)
LVE: 103089326(WNT2) 103089709(WNT2B)
OOR: 101279049(WNT2) 101289035(WNT2B)
ECB: 100056092(WNT2) 100063931(WNT2B)
EPZ: 103541803(WNT2B) 103550603(WNT2)
EAI: 106828591(WNT2B) 106829346(WNT2)
MYB: 102255951(WNT2B) 102261227(WNT2)
MYD: 102752980(WNT2) 102765024(WNT2B)
HAI: 109389334(WNT2) 109391554(WNT2B)
RSS: 109446725(WNT2B) 109453462(WNT2)
PALE: 102880959(WNT2B) 102885080(WNT2)
LAV: 100653551(WNT2B) 100657046(WNT2)
MDO: 100011991(WNT2) 100033140(WNT2B)
SHR: 100918306(WNT2) 100918389(WNT2B)
OAA: 100077640(WNT2) 100087253(WNT2B)
GGA: 374243(WNT2B) 417769(WNT2)
MGP: 100545665(WNT2) 100551435(WNT2B)
CJO: 107309102(WNT2) 107324859(WNT2B)
APLA: 101799824 101800865(WNT2B)
ACYG: 106041264(WNT2B) 106042052(WNT2)
TGU: 100221216(WNT2) 100227493(WNT2B)
GFR: 102039793(WNT2B) 102040836(WNT2)
FAB: 101807109(WNT2B) 101821440(WNT2)
PHI: 102099201(WNT2) 102111953(WNT2B)
PMAJ: 107204737(WNT2) 107215039(WNT2B)
CCW: 104692318(WNT2B) 104698447(WNT2)
FPG: 101916797(WNT2B) 101924187(WNT2)
FCH: 102050583(WNT2) 102054880(WNT2B)
EGZ: 104126790(WNT2B) 104133417(WNT2)
AAM: 106485278(WNT2B) 106488127(WNT2)
ASN: 102377917(WNT2B) 102388685(WNT2)
AMJ: 102569359(WNT2) 102575620(WNT2B)
PSS: 102443393(WNT2B) 102448332(WNT2)
CMY: 102929895(WNT2B) 102936696(WNT2)
CPIC: 101932483(WNT2) 101949084(WNT2B)
ACS: 100559857(wnt2b)
PVT: 110072347(WNT2B)
PBI: 103048288(WNT2B)
GJA: 107110304(WNT2B)
XLA: 108711137 108713107 378566(wnt2b.L)
XTR: 100038261(wnt2) 100491761(wnt2b)
NPR: 108790556(WNT2B) 108802068(WNT2)
DRE: 359837(wnt2ba) 556087(wnt2bb)
IPU: 108263957(wnt2) 108266047(wnt2b) 108271793
AMEX: 103029625 103033339(wnt2) 103046094(wnt2b)
TRU: 100137508(wnt2) 101071463(wnt2b) 101071718
LCO: 104922301(wnt2b) 104925521(wnt2) 104932064
PRET: 103464374(wnt2b) 103465636(wnt2) 103467401
CSEM: 103379582(wnt2) 103384543 103386704(wnt2b)
LCF: 108889451(wnt2b) 108893965(wnt2) 108902118
LCM: 102345664(WNT2) 102352078(WNT2B)
CMK: 103179360(wnt2) 103182404(wnt2b)
CIN: 778720
APLC: 110984921
SKO: 100303493(Wnt2)
FCD: 110856954
DPX: DAPPUDRAFT_43478(WNT2)
TSP: Tsp_07695
CRG: 105340175
MYI: 110456287
OBI: 106880752
LAK: 106154358
SHX: MS3_03376
EPA: 110234822
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kawakami Y, Capdevila J, Buscher D, Itoh T, Rodriguez Esteban C, Izpisua Belmonte JC
  Title
WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo.
  Journal
Cell 104:891-900 (2001)
DOI:10.1016/S0092-8674(01)00285-9
  Sequence
[gga:374243]
Reference
PMID:2971536
  Authors
Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS, et al.
  Title
Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless.
  Journal
EMBO J 7:1743-8 (1988)
  Sequence
[hsa:7472]
Reference
PMID:8761309
  Authors
Katoh M, Hirai M, Sugimura T, Terada M
  Title
Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family.
  Journal
Oncogene 13:873-6 (1996)
  Sequence
[hsa:7482]

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