KEGG ORTHOLOGY: K00355

ORTHOLOGY: K00355

Entry

K00355 KO

Name

NQO1

Definition

NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]

Pathway

ko00130

Ubiquinone and other terpenoid-quinone biosynthesis

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    K00355  NQO1; NAD(P)H dehydrogenase (quinone)
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.5  With a quinone or similar compound as acceptor
    1.6.5.2  NAD(P)H dehydrogenase (quinone)
     K00355  NQO1; NAD(P)H dehydrogenase (quinone)

Other DBs

RN:

R02964 R03643 R03816

COG:

COG2249

GO:

0003955

Genes

HSA:	1728(NQO1)
PTR:	468012(NQO1)
PPS:	100976664(NQO1)
GGO:	101151289(NQO1)
PON:	100172039(NQO1)
MCC:	705635(NQO1)
MMU:	18104(Nqo1)
RNO:	24314(Nqo1)
CFA:	610935(NQO1)
AML:	100475899
FCA:	101097859(NQO1)
BTA:	519632(NQO1)
SSC:	100286873(NQO1)
ECB:	100067237
MDO:	100028121
SHR:	100916256(NQO1)
OAA:	100077094
GGA:	769737(NQO1)
MGP:	100548559
ACS:	100561335
XLA:	100049751(nqo1)
XTR:	549222(nqo1)
DRE:	322506(nqo1)
TRU:	101077116
OLA:	100049469(nqo1) 101170885
TVA:	TVAG_293430
EBT:	EBL_c38750
ECA:	ECA0951
PCT:	PC1_0837
PCC:	PCC21_008670
ENC:	ECL_02110
ENO:	ECENHK_10475
ESC:	Entcl_3821
ENL:	A3UG_10610
ESA:	ESA_01483
CSK:	ES15_1716
CTU:	CTU_24360
KPN:	KPN_04757
KPU:	KP1_0706
KPM:	KPHS_06010
KPP:	A79E_4397
KPE:	KPK_4873
KPO:	KPN2242_01905
KVA:	Kvar_4510
KOX:	KOX_08620 KOX_09820
SPE:	Spro_2460
SRR:	SerAS9_2440
SRS:	SerAS12_2441
SRA:	SerAS13_2442
SMAF:	D781_2123 D781_3955
SMW:	SMWW4_v1c09360 SMWW4_v1c24540
XNE:	XNC1_0071
PAM:	PANA_0914(nqo2)
PLF:	PANA5342_3395
PAJ:	PAJ_0246(nqo2)
PAQ:	PAGR_g3291
PVA:	Pvag_pPag30204
PAO:	Pat9b_0552 Pat9b_4108
RAH:	Rahaq_1059
RAQ:	Rahaq2_1128
RAA:	Q7S_05065
HSO:	HS_0336(kefF) HS_0573
HSM:	HSM_1601
ASU:	Asuc_0951
XCC:	XCC0060
XCB:	XC_0060
XAC:	XAC0088 XAC2229
XAX:	XACM_0061
XAO:	XAC29_00445 XAC29_11285
XCI:	XCAW_00476(mdaB)
SML:	Smlt1299
SMT:	Smal_2429 Smal_3642
BUJ:	BurJV3_2491 BurJV3_3678
SMZ:	SMD_2620 SMD_3828
VHA:	VIBHAR_04777
PAE:	PA1224 PA1225 PA4975
PAU:	PA14_48440 PA14_65760
PAP:	PSPA7_4162 PSPA7_4164 PSPA7_5708
PAG:	PLES_40841 PLES_40851 PLES_53631
PAF:	PAM18_3808 PAM18_3809 PAM18_5086
PNC:	NCGM2_0543 NCGM2_2104
PDK:	PADK2_19515 PADK2_19520 PADK2_26365
PPU:	PP_3720
PPF:	Pput_2044
PPG:	PputGB1_2068 PputGB1_2187
PPW:	PputW619_3074
PPT:	PPS_3187
PPB:	PPUBIRD1_2042 PPUBIRD1_3259
PPI:	YSA_09441
PPX:	T1E_1734(nqo2) T1E_4847(nqo1)
PPUH:	B479_15815 B479_16385
PPUU:	PputUW4_02746
PSB:	Psyr_0122 Psyr_3797
PFL:	PFL_2716 PFL_3429
PFO:	Pfl01_3534
PFS:	PFLU2771
PFE:	PSF113_2268 PSF113_2821
PFC:	PflA506_2922
PEN:	PSEEN2157 PSEEN2559 PSEEN3245
PMY:	Pmen_3208
PSA:	PST_1625
PSZ:	PSTAB_1535
PSR:	PSTAA_1654
PSC:	A458_08710
PSH:	Psest_2747
PBA:	PSEBR_a2968 PSEBR_a3458
PFV:	Psefu_1385
PDR:	H681_24920
AVN:	Avin_20800
ACD:	AOLE_03345
ACB:	A1S_2772
ABM:	ABSDF0690
ABY:	ABAYE0712
ABC:	ACICU_03022
ABN:	AB57_3273
ABB:	ABBFA_000695
ABX:	ABK1_3074
ABZ:	ABZJ_03205
ABR:	ABTJ_00691
ABD:	ABTW07_3243
ABH:	M3Q_3252
ABAD:	ABD1_27180
ACC:	BDGL_002224(nqO2)
CSA:	Csal_0147
ADI:	B5T_03358
AVR:	B565_2515
CVI:	CV_0290
RPF:	Rpic12D_4017
REU:	Reut_C6287
REH:	H16_B2315
RME:	Rmet_4021
CNC:	CNE_2c22750
BMA:	BMAA1893
BMV:	BMASAVP1_0903
BML:	BMA10229_1191
BMN:	BMA10247_A2166
BPS:	BPSS0188
BPM:	BURPS1710b_A1711
BPL:	BURPS1106A_A0261
BPD:	BURPS668_A0353
BPZ:	BP1026B_II0210
BPQ:	BPC006_II0249
BVI:	Bcep1808_4156
BUR:	Bcep18194_B2332
BCN:	Bcen_4596
BCH:	Bcen2424_3767
BCM:	Bcenmc03_3756
BCJ:	BCAM0802 BCAS0623
BAM:	Bamb_5496
BAC:	BamMC406_3642
BMU:	Bmul_4963
BMJ:	BMULJ_03551(nqo1)
BCT:	GEM_4558 GEM_4996
BXE:	Bxe_A1917 Bxe_B2110
BUG:	BC1001_5284
BGE:	BC1002_3493
BGF:	BC1003_4134
BGD:	bgla_2g07280
BYI:	BYI23_C001170 BYI23_C001310 BYI23_D009000
BUK:	MYA_3857
BPX:	BUPH_05798
BPT:	Bpet2092
AXY:	AXYL_05483
AKA:	TKWG_19905
RFR:	Rfer_2434
AAV:	Aave_3540
AAA:	Acav_2799 Acav_3445
DEL:	DelCs14_3722
VAP:	Vapar_2044
VPE:	Varpa_3021 Varpa_3819
MPT:	Mpe_A3318
CFU:	CFU_1367
RGE:	RGE_23910
AZO:	azo1477(drgA) azo1583(nqo1)
AZA:	AZKH_1989
DBA:	Dbac_3453
MSD:	MYSTI_05724
PUB:	SAR11_1255
MLO:	mll7814
MCI:	Mesci_6213
MOP:	Mesop_2797 Mesop_5279
MAM:	Mesau_01763
SME:	SMc03185
SMK:	Sinme_2970
SMQ:	SinmeB_2745
SMX:	SM11_chr3088
SMI:	BN406_02772
SMEG:	C770_GR4Chr3045
SMEL:	SM2011_c03185
SFH:	SFHH103_02528
ARA:	Arad_0487
RLE:	RL2909
RLG:	Rleg_2441
RTR:	RTCIAT899_CH16040
BRA:	BRADO5589
BBT:	BBta_6111
RPA:	RPA4746
RPB:	RPB_0823
RPC:	RPC_0109
RPT:	Rpal_5228
RPX:	Rpdx1_4923
AOL:	S58_20170
AZC:	AZC_4684
MRD:	Mrad2831_1088
MNO:	Mnod_4996
BID:	Bind_1407
HMC:	HYPMC_3594
CAK:	Caul_2450
RSP:	RSP_3025
RSH:	Rsph17029_3569 Rsph17029_3750
RSK:	RSKD131_4287
RLI:	RLO149_c001470 RLO149_c020640
ZMO:	ZMO1949
SPHM:	G432_16600
GOH:	B932_2223 B932_2235 B932_3263
GDI:	GDI_0214 GDI_1006
GXY:	GLX_23460
RRU:	Rru_A1713 Rru_A3066
RRF:	F11_08820 F11_15710
ABS:	AZOBR_p1130031
TMO:	TMO_c0421 TMO_c0545
APM:	HIMB5_00008940
BLI:	BL03025
BLD:	BLi00867(ydeQ)
BAO:	BAMF_0798(RBAM_008460)
BAY:	RBAM_008460
BAQ:	BACAU_0821(ydeQ)
BYA:	BANAU_0764
BAMP:	B938_04070
BAML:	BAM5036_0756(ydeQ)
BAZ:	BAMTA208_03840
BQL:	LL3_00855
BXH:	BAXH7_00802
BQY:	MUS_0853
BAMI:	KSO_015585
BHA:	BH2748
BAN:	BA_3358 BA_5191
BAR:	GBAA_3358 GBAA_5191
BAT:	BAS3112 BAS4826
BAH:	BAMEG_1268 BAMEG_5248
BAI:	BAA_3392 BAA_5227
BAX:	H9401_3196 H9401_4956
BAL:	BACI_c32550 BACI_c49620
BCE:	BC4958
BCA:	BCE_3317 BCE_5095
BCZ:	BCZK3002 BCZK3128 BCZK4683
BCR:	BCAH187_A3330 BCAH187_A5100
BCB:	BCB4264_A3310 BCB4264_A5101
BCU:	BCAH820_3331 BCAH820_5061
BCG:	BCG9842_B0139 BCG9842_B1921
BCQ:	BCQ_3108 BCQ_4775
BCX:	BCA_3394 BCA_5090
BNC:	BCN_3124 BCN_4853
BCF:	bcf_16345 bcf_24830
BCER:	BCK_10480 BCK_18605
BTK:	BT9727_3099 BT9727_4666
BTL:	BALH_2976 BALH_3075 BALH_4491
BTB:	BMB171_C2985 BMB171_C4569
BTT:	HD73_3566 HD73_5327
BTC:	CT43_CH3222 CT43_CH5017
BTF:	YBT020_16265 YBT020_24600
BTM:	MC28_2441 MC28_4222
BTG:	BTB_c33550 BTB_c51820
BTI:	BTG_02965 BTG_24055
BTN:	BTF1_13915 BTF1_23345
BTHT:	H175_ch3278 H175_ch5099
BWE:	BcerKBAB4_3035 BcerKBAB4_4778
BPU:	BPUM_0365 BPUM_2597
BMQ:	BMQ_3657
BMD:	BMD_2478
BSE:	Bsel_1498
BCO:	Bcell_0819
OIH:	OB3182
SWA:	A284_12342
LSP:	Bsph_2062
PJD:	Pjdr2_0582 Pjdr2_5083
PPY:	PPE_00661 PPE_01828
PPM:	PPSC2_c0735 PPSC2_c2026
PPO:	PPM_0683(M1-870) PPM_1825(M1_2093)
PMS:	KNP414_04375 KNP414_04849
PMQ:	PM3016_3796 PM3016_4257
PMW:	B2K_19710 B2K_22075
PTA:	HPL003_17840
SMU:	SMU_1420
SMC:	SmuNN2025_0681
SMJ:	SMULJ23_0689
SMUT:	SMUGS5_06335
STU:	STH8232_0152(pig-9)
SSA:	SSA_0047
SSI:	SSU1434
SST:	SSUST3_1465
SSF:	SSUA7_1452
SSK:	SSUD12_1578
SSQ:	SSUD9_1628
SSW:	SSGZ1_1452
SUI:	SSUJS14_1590
SUO:	SSU12_1567
SRP:	SSUST1_1499
SUP:	YYK_06835
SSUS:	NJAUSS_1498
SGO:	SGO_2084
SCP:	HMPREF0833_11639
SCF:	Spaf_0267
SSR:	SALIVB_1940(NQO2)
STF:	Ssal_00204
STJ:	SALIVA_1875
OOE:	OEOE_1767
CAE:	SMB_G0018(ycaK)
CAY:	CEA_G0018
CCB:	Clocel_3353
CSR:	Cspa_c37650
AMT:	Amet_3652
TJR:	TherJR_1268
DMI:	Desmer_2927
TPZ:	Tph_c13230
VPR:	Vpar_1733
MSM:	MSMEG_5564
MSG:	MSMEI_0277 MSMEI_5413
NCY:	NOCYR_1166
NBR:	O3I_010235 O3I_019540
RHA:	RHA1_ro06352
RER:	RER_19670
ROP:	ROP_64130
GBR:	Gbro_2368
GPO:	GPOL_c03650
TPR:	Tpau_2353 Tpau_3083
SSX:	SACTE_5530
SVL:	Strvi_0619
SBH:	SBI_06849
SHY:	SHJG_0297
SHO:	SHJGH_0131
SALB:	XNR_2670
KSK:	KSE_74970
CMI:	CMM_2373
CMC:	CMN_00520 CMN_02329
KSE:	Ksed_17880
SKE:	Sked_19550
NAL:	B005_4442
FRA:	Francci3_2561
FAL:	FRAAL6868
AMI:	Amir_3388
STP:	Strop_1404
SAQ:	Sare_1362
CAI:	Caci_4131
SNA:	Snas_4047
BBI:	BBIF_1053
BBP:	BBPR_1114
BBF:	BBB_1041(nqo)
BAST:	BAST_0900 BAST_0973
CWO:	Cwoe_3978
TBE:	Trebr_1004
TAZ:	TREAZ_1524
OSP:	Odosp_1747
NKO:	Niako_0868
SCN:	Solca_3580
ZGA:	zobellia_2660(wrbA)
MRS:	Murru_2882
HTE:	Hydth_1741
SUL:	SYO3AOP1_0608
MAC:	MA0326
MBA:	Mbar_A1308
MMA:	MM_1581
MMAZ:	MmTuc01_1646
MEV:	Metev_0215
MZH:	Mzhil_1248
MPY:	Mpsy_2849
MHZ:	Metho_1023
MEW:	MSWAN_0984

» show all

Reference

PMID:21239697

Authors

Tie JK, Jin DY, Straight DL, Stafford DW

Title

Functional study of the vitamin K cycle in mammalian cells.

Journal

Blood 117:2967-74 (2011)

All links

Ontology (8)   
   KEGG BRITE (6)   
   GO (1)   
   COG (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Drug (5)   
   KEGG DRUG (5)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
   KEGG RCLASS (1)   
Gene (4767)   
   KEGG GENES (463)   
   KEGG DGENES (3)   
   KEGG EGENES (11)   
   KEGG MGENES (4290)   
Protein sequence (216)   
   UniProt (216)   
Literature (1)   
   PubMed (1)   
All databases (5004)   

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