KEGG   ORTHOLOGY: K00431Help
Entry
K00431                      KO                                     

Name
TPO
Definition
thyroid peroxidase [EC:1.11.1.8]
Pathway
Tyrosine metabolism
Thyroid hormone synthesis
Autoimmune thyroid disease
Module
M00043  
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Disease
H00251  
Thyroid dyshormonogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00350 Tyrosine metabolism
    K00431  TPO; thyroid peroxidase
 Organismal Systems
  Endocrine system
   04918 Thyroid hormone synthesis
    K00431  TPO; thyroid peroxidase
 Human Diseases
  Immune diseases
   05320 Autoimmune thyroid disease
    K00431  TPO; thyroid peroxidase
KEGG modules [BR:ko00002]
 Pathway module
  Nucleotide and amino acid metabolism
   Aromatic amino acid metabolism
    M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
     K00431  TPO; thyroid peroxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.8  iodide peroxidase
     K00431  TPO; thyroid peroxidase
Cytokines [BR:ko04052]
 Class I cytokines (hematopoietin family)
  Single chain family
   K00431  TPO; thyroid peroxidase
BRITE hierarchy
Other DBs
Genes
HSA: 
7173(TPO)
PTR: 
470287(TPO)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
721610(TPO)
MCF: 
CJC: 
MMU: 
22018(Tpo)
RNO: 
54314(Tpo)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
403521(TPO)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
525013(TPO)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
776120(TPO)
MGP: 
APLA: 
TGU: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XTR: 
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1497352
  Authors
Rawitch AB, Pollock G, Yang SX, Taurog A
  Title
Thyroid peroxidase glycosylation: the location and nature of the N-linked oligosaccharide units in porcine thyroid peroxidase.
  Journal
Arch Biochem Biophys 297:321-7 (1992)
  Sequence
Reference
  Authors
Ruf J, Carayon P
  Title
Structural and functional aspects of thyroid peroxidase.
  Journal
Arch Biochem Biophys 445:269-77 (2006)

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