KEGG   ORTHOLOGY: K00445Help
Entry
K00445                      KO                                     

Name
WNT6
Definition
wingless-type MMTV integration site family, member 6
Pathway
mTOR signaling pathway
Wnt signaling pathway
Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells
Melanogenesis
HTLV-I infection
Pathways in cancer
Proteoglycans in cancer
Basal cell carcinoma
Breast cancer
Module
M00677  
Wnt signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   04390 Hippo signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   04150 mTOR signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 Cellular Processes
  Cellular community
   04550 Signaling pathways regulating pluripotency of stem cells
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 Organismal Systems
  Endocrine system
   04916 Melanogenesis
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05205 Proteoglycans in cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05217 Basal cell carcinoma
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05224 Breast cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  Infectious diseases
   05166 HTLV-I infection
    K00445  WNT6; wingless-type MMTV integration site family, member 6
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00677  Wnt signaling
     K00445  WNT6; wingless-type MMTV integration site family, member 6
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Morphogens
   K00445  WNT6; wingless-type MMTV integration site family, member 6
BRITE hierarchy
Genes
HSA: 
7475(WNT6)
PTR: 
742467(WNT6)
PPS: 
100987794(WNT6)
GGO: 
101132496(WNT6)
PON: 
100440643(WNT6)
NLE: 
100606818(WNT6)
MCC: 
700573(WNT6)
MCF: 
102132660(WNT6)
CSAB: 
103217884(WNT6)
RRO: 
104660036(WNT6)
CJC: 
100394855(WNT6)
SBQ: 
101028364(WNT6)
MMU: 
22420(Wnt6)
RNO: 
316526(Wnt6)
CGE: 
100751289(Wnt6)
NGI: 
103727729(Wnt6)
HGL: 
101698823(Wnt6)
OCU: 
100348986(WNT6)
TUP: 
102483667(WNT6)
CFA: 
488527(WNT6)
AML: 
100467896(WNT6)
FCA: 
101099392(WNT6)
PTG: 
102956004(WNT6)
BTA: 
505075(WNT6)
BOM: 
102286828(WNT6)
PHD: 
102320956(WNT6)
OAS: 
101111785(WNT6)
SSC: 
CFR: 
102511574(WNT6)
BACU: 
102997453(WNT6)
LVE: 
103079243(WNT6)
ECB: 
100058824(WNT6)
MYB: 
102256374(WNT6)
MYD: 
102757803(WNT6)
PALE: 
102882368(WNT6)
LAV: 
100675069(WNT6)
MDO: 
100010861(WNT6)
SHR: 
100933826(WNT6)
OAA: 
100089786(WNT6)
GGA: 
395235(WNT6)
MGP: 
100540128(WNT6)
CJO: 
107317037(WNT6)
APLA: 
101803438(WNT6)
TGU: 
100230318(WNT6)
GFR: 
102035490(WNT6)
FAB: 
101819686(WNT6)
PHI: 
102100841(WNT6)
CCW: 
104693964(WNT6)
FPG: 
101921385(WNT6)
FCH: 
102054753(WNT6)
CLV: 
102085008(WNT6)
AAM: 
106499139(WNT6)
ASN: 
102377243(WNT6)
AMJ: 
106737397(WNT6)
PSS: 
102457308(WNT6)
ACS: 
100565609(wnt6)
PBI: 
103054454(WNT6)
GJA: 
107107564(WNT6)
XLA: 
378676(wnt6)
XTR: 
101733784(wnt6)
DRE: 
100332722(wnt6a) 561831(wnt6b)
TRU: 
101062888(wnt6)
TNG: 
MZE: 
101474169(wnt6)
OLA: 
101174712(wnt6)
XMA: 
102234174(wnt6)
SASA: 
LCM: 
CMK: 
BFO: 
SPU: 
SKO: 
100313763(Wnt6)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
Dyak_GE14461(dyak_GLEANR_1458)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
413501(Wnt6)
BIM: 
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
656429(Wnt6)
BMOR: 
DPL: 
PXY: 
PHU: 
DPX: 
ISC: 
LGI: 
CRG: 
OBI: 
ADF: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kirikoshi H, Sekihara H, Katoh M
  Title
WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells.
  Journal
Biochem Biophys Res Commun 283:798-805 (2001)
  Sequence
[hsa:7475]
Reference
  Authors
Yuan G, Regel I, Lian F, Friedrich T, Hitkova I, Hofheinz RD, Strobel P, Langer R, Keller G, Rocken C, Zimmermann W, Schmid RM, Ebert MP, Burgermeister E
  Title
WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells.
  Journal
Oncogene 32:375-87 (2013)
  Sequence
[hsa:7475]

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