KEGG   ORTHOLOGY: K00445Help
Entry
K00445                      KO                                     

Name
WNT6
Definition
wingless-type MMTV integration site family, member 6
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing's syndrome
ko05165  Human papillomavirus infection
ko05166  HTLV-I infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Module
M00677  Wnt signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   04390 Hippo signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   04150 mTOR signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 Organismal Systems
  Endocrine system
   04916 Melanogenesis
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05205 Proteoglycans in cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05225 Hepatocellular carcinoma
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05226 Gastric cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05217 Basal cell carcinoma
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05224 Breast cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  Infectious diseases
   05166 HTLV-I infection
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05165 Human papillomavirus infection
    K00445  WNT6; wingless-type MMTV integration site family, member 6
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00677  Wnt signaling
     K00445  WNT6; wingless-type MMTV integration site family, member 6
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Morphogens
   K00445  WNT6; wingless-type MMTV integration site family, member 6
BRITE hierarchy
Genes
HSA: 7475(WNT6)
PTR: 742467(WNT6)
PPS: 100987794(WNT6)
GGO: 101132496(WNT6)
PON: 100440643(WNT6)
NLE: 100606818(WNT6)
MCC: 700573(WNT6)
MCF: 102132660(WNT6)
CSAB: 103217884(WNT6)
RRO: 104660036(WNT6)
RBB: 108518481(WNT6)
CJC: 100394855(WNT6)
SBQ: 101028364(WNT6)
MMU: 22420(Wnt6)
RNO: 316526(Wnt6)
CGE: 100751289(Wnt6)
NGI: 103727729(Wnt6)
HGL: 101698823(Wnt6)
CCAN: 109693790(Wnt6)
OCU: 100348986(WNT6)
TUP: 102483667(WNT6)
CFA: 488527(WNT6)
AML: 100467896(WNT6)
ORO: 101374890(WNT6)
FCA: 101099392(WNT6)
PTG: 102956004(WNT6)
BTA: 505075(WNT6)
BOM: 102286828(WNT6)
BIU: 109570782(WNT6)
PHD: 102320956(WNT6)
CHX: 108637658(WNT6)
OAS: 101111785(WNT6)
SSC: 100622044(WNT6)
CFR: 102511574(WNT6)
CDK: 105096131(WNT6)
BACU: 102997453(WNT6)
LVE: 103079243(WNT6)
OOR: 101288015(WNT6)
ECB: 100058824(WNT6)
EPZ: 103567913(WNT6)
EAI: 106838461(WNT6)
MYB: 102256374(WNT6)
MYD: 102757803(WNT6)
HAI: 109380535(WNT6)
RSS: 109452642(WNT6)
PALE: 102882368(WNT6)
LAV: 100675069(WNT6)
TMU: 101341737
MDO: 100010861(WNT6)
SHR: 100933826(WNT6)
OAA: 100089786(WNT6)
GGA: 395235(WNT6)
MGP: 100540128(WNT6)
CJO: 107317037(WNT6)
APLA: 101803438(WNT6)
ACYG: 106039313(WNT6)
TGU: 100230318(WNT6)
GFR: 102035490(WNT6)
FAB: 101819686(WNT6)
PHI: 102100841(WNT6)
PMAJ: 107207801(WNT6)
CCW: 104693964(WNT6)
FPG: 101921385(WNT6)
FCH: 102054753(WNT6)
CLV: 102085008(WNT6)
EGZ: 104132404(WNT6)
AAM: 106499139(WNT6)
ASN: 102377243(WNT6)
AMJ: 106737397(WNT6)
PSS: 102457308(WNT6)
CPIC: 101949600(WNT6)
ACS: 100565609(wnt6)
PVT: 110078170(WNT6)
PBI: 103054454(WNT6)
GJA: 107107564(WNT6)
XLA: 108701298(wnt6.L) 378676(wnt6.S)
XTR: 101733784(wnt6)
NPR: 108801546(WNT6)
DRE: 100332722(wnt6a) 561831(wnt6b)
IPU: 108266110(wnt6) 108273177
AMEX: 103038704 103041984(wnt6)
TRU: 101062888(wnt6)
LCO: 104919603(wnt6)
NCC: 104943745(wnt6)
MZE: 101474169(wnt6)
OLA: 101174712(wnt6)
XMA: 102234174(wnt6)
PRET: 103460530(wnt6)
NFU: 107390192(wnt6)
LCF: 108902815(wnt6)
HCQ: 109522420(wnt6)
BPEC: 110156189(wnt6)
SASA: 106581837(wnt6) 106586152
ELS: 105029531(wnt6)
SFM: 108927964(wnt6)
LCM: 102350297 102352652(WNT6)
SPU: 585147
APLC: 110984744
SKO: 100313763(Wnt6)
DME: Dmel_CG4969(Wnt6)
DSI: Dsimw501_GD23460(Dsim_wg)
MDE: 101898284
AAG: 5564830
AME: 413501(Wnt6)
BIM: 100745430
BTER: 100647833
SOC: 105200052
AEC: 105150855
ACEP: 105618731
PBAR: 105429522
HST: 105189290
CFO: 105258968
LHU: 105676116
PGC: 109859095
NVI: 100119613
TCA: 656429(Wnt6)
DPA: 109545719
NVL: 108563654
BMOR: 101741216
PMAC: 106714253
PRAP: 110994201
PXY: 105397939
ZNE: 110828845
FCD: 110849830
DPX: DAPPUDRAFT_290641(WNT6)
CRG: 105348241
MYI: 110462024
OBI: 106878314
LAK: 106180551
ADF: 107333377
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kirikoshi H, Sekihara H, Katoh M
  Title
WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells.
  Journal
Biochem Biophys Res Commun 283:798-805 (2001)
DOI:10.1006/bbrc.2001.4855
  Sequence
[hsa:7475]
Reference
  Authors
Yuan G, Regel I, Lian F, Friedrich T, Hitkova I, Hofheinz RD, Strobel P, Langer R, Keller G, Rocken C, Zimmermann W, Schmid RM, Ebert MP, Burgermeister E
  Title
WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells.
  Journal
Oncogene 32:375-87 (2013)
DOI:10.1038/onc.2012.40
  Sequence
[hsa:7475]

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