KEGG   ORTHOLOGY: K00458Help
Entry
K00458                      KO                                     

Name
ALOX12
Definition
arachidonate 12-lipoxygenase [EC:1.13.11.31]
Pathway
Arachidonic acid metabolism
Metabolic pathways
Antifolate resistance
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00590 Arachidonic acid metabolism
    K00458  ALOX12; arachidonate 12-lipoxygenase
 Organismal Systems
  Nervous system
   04726 Serotonergic synapse
    K00458  ALOX12; arachidonate 12-lipoxygenase
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K00458  ALOX12; arachidonate 12-lipoxygenase
 Human Diseases
  Drug resistance
   01523 Antifolate resistance
    K00458  ALOX12; arachidonate 12-lipoxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.31  arachidonate 12-lipoxygenase
     K00458  ALOX12; arachidonate 12-lipoxygenase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
HSA: 
239(ALOX12)
PTR: 
455242(ALOX12) 455243
PPS: 
100992721(ALOX12)
GGO: 
PON: 
100448016(ALOX12)
NLE: 
MCC: 
713683 713748(ALOX12)
MCF: 
CSAB: 
RRO: 
RBB: 
CJC: 
100400641(ALOX12)
SBQ: 
101051396(ALOX12)
MMU: 
11684(Alox12) 11685(Alox12e)
RNO: 
287454(Alox12) 303252(Alox12e)
CGE: 
100764620(Alox12) 100764916(Alox15)
NGI: 
HGL: 
CCAN: 
OCU: 
100340525(ALOX12)
TUP: 
CFA: 
479476(ALOX12) 607567
AML: 
100471037(ALOX12)
UMR: 
103660455(ALOX12)
FCA: 
101094304(ALOX12)
PTG: 
102969788(ALOX12)
AJU: 
BTA: 
407169(ALOX12) 787450(ALOX12E)
BOM: 
BIU: 
PHD: 
CHX: 
OAS: 
SSC: 
100620614(ALOX12)
CFR: 
102504047(ALOX12)
CDK: 
105103060(ALOX12)
BACU: 
103020542(ALOX12)
LVE: 
103074060(ALOX12)
ECB: 
100072916(ALOX12)
EPZ: 
103561430(ALOX12)
EAI: 
106844160(ALOX12)
MYB: 
MYD: 
HAI: 
109394599(ALOX12)
RSS: 
109439024(ALOX12)
PALE: 
102897481(ALOX12)
LAV: 
100656524(ALOX12)
MDO: 
SHR: 
100933073(ALOX12)
OAA: 
DRE: 
322732(alox12)
IPU: 
LCF: 
HCQ: 
109516476(alox15)
SASA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2244907
  Authors
Yoshimoto T, Yamamoto Y, Arakawa T, Suzuki H, Yamamoto S, Yokoyama C, Tanabe T, Toh H
  Title
Molecular cloning and expression of human arachidonate 12-lipoxygenase.
  Journal
Biochem Biophys Res Commun 172:1230-5 (1990)
DOI:10.1016/0006-291X(90)91580-L
  Sequence
[hsa:239]
Reference
  Authors
Yoshimoto T, Takahashi Y
  Title
Arachidonate 12-lipoxygenases.
  Journal
Prostaglandins Other Lipid Mediat 68-69:245-62 (2002)
DOI:10.1016/S0090-6980(02)00034-5

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