KEGG   ORTHOLOGY: K00489Help
Entry
K00489                      KO                                     

Name
CYP7A1
Definition
cholesterol 7alpha-monooxygenase [EC:1.14.13.17]
Pathway
Primary bile acid biosynthesis
Steroid hormone biosynthesis
PPAR signaling pathway
Bile secretion
Module
M00104  
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00120 Primary bile acid biosynthesis
    K00489  CYP7A1; cholesterol 7alpha-monooxygenase
   00140 Steroid hormone biosynthesis
    K00489  CYP7A1; cholesterol 7alpha-monooxygenase
 Organismal Systems
  Endocrine system
   03320 PPAR signaling pathway
    K00489  CYP7A1; cholesterol 7alpha-monooxygenase
  Digestive system
   04976 Bile secretion
    K00489  CYP7A1; cholesterol 7alpha-monooxygenase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Sterol biosynthesis
    M00104  Bile acid biosynthesis, cholesterol => cholate
     K00489  CYP7A1; cholesterol 7alpha-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.17  cholesterol 7alpha-monooxygenase
     K00489  CYP7A1; cholesterol 7alpha-monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP7 family
   K00489  CYP7A1; cholesterol 7alpha-monooxygenase
BRITE hierarchy
Other DBs
Genes
HSA: 
1581(CYP7A1)
PTR: 
464191(CYP7A1)
PPS: 
GGO: 
PON: 
MCC: 
698127(CYP7A1)
MCF: 
102132452(CYP7A1)
MMU: 
13122(Cyp7a1)
RNO: 
25428(Cyp7a1)
CGE: 
100689275(Cyp7a1)
HGL: 
TUP: 
CFA: 
486962(CYP7A1)
AML: 
FCA: 
PTG: 
BTA: 
510507(CYP7A1)
BOM: 
PHD: 
CHX: 
SSC: 
448985(CYP7A1)
CFR: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
100022261(CYP7A1)
SHR: 
OAA: 
GGA: 
414834(CYP7A1)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
101790267(CYP7A1)
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
CMY: 
ACS: 
XTR: 
DRE: 
394148(cyp7a1a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
SSL: 
BFU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Norlin M, Wikvall K
  Title
Enzymes in the conversion of cholesterol into bile acids.
  Journal
Curr Mol Med 7:199-218 (2007)

DBGET integrated database retrieval system