KEGG   ORTHOLOGY: K00910Help
Entry
K00910                      KO                                     

Name
ADRBK, GRK
Definition
beta-adrenergic-receptor kinase [EC:2.7.11.15]
Pathway
Chemokine signaling pathway
Endocytosis
Hedgehog signaling pathway
Glutamatergic synapse
Olfactory transduction
Phototransduction - fly
Morphine addiction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04340 Hedgehog signaling pathway
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
 Organismal Systems
  Immune system
   04062 Chemokine signaling pathway
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
  Nervous system
   04724 Glutamatergic synapse
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
  Sensory system
   04745 Phototransduction - fly
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
   04740 Olfactory transduction
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.15  beta-adrenergic-receptor kinase
     K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: AGC group
  GRK family [OT]
   K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
156(GRK2) 157(GRK3)
PTR: 
100614029(GRK3) 451363(GRK2)
PPS: 
100984800(GRK3) 100991802(GRK2)
GGO: 
101140574(GRK2) 101148325(GRK3)
PON: 
100454669(GRK3) 100461893(GRK2)
NLE: 
MCC: 
714510(GRK3) 721754(GRK2)
MCF: 
102141861(GRK2) 102141926(GRK3)
CSAB: 
103219132(GRK2) 103223079(GRK3)
RRO: 
104664749(GRK2) 104671949(GRK3)
RBB: 
108515962(GRK3) 108518610(GRK2)
CJC: 
100396838(GRK3)
SBQ: 
101027803(ADRBK2) 101049133(ADRBK1)
MMU: 
110355(Grk2) 320129(Grk3)
RNO: 
25238(Grk2) 25372(Grk3)
CGE: 
100761290(Adrbk2) 100762552(Grk2)
NGI: 
103725575(Grk2) 103746714(Grk3)
HGL: 
101708742(Grk3) 101708906(Grk2)
CCAN: 
OCU: 
100349708(GRK3) 103345045(GRK2)
TUP: 
102482004(GRK2) 102499442(GRK3)
CFA: 
483701(GRK2) 486327(GRK3)
AML: 
100469854(GRK2) 100475417(GRK3)
UMR: 
103659256(GRK3) 103679607(GRK2)
FCA: 
101090393(GRK3) 101101082(GRK2)
PTG: 
102957039(GRK3) 102970752(GRK2)
AJU: 
106971185(GRK2) 106982294(GRK3)
BTA: 
282136(GRK3) 282682(GRK2)
BOM: 
102286310(GRK2) 102288247(GRK3)
BIU: 
109554452(GRK2) 109571286(GRK3)
PHD: 
102322462(GRK3) 102323551(GRK2)
CHX: 
102180735(GRK2) 102185296(GRK3)
OAS: 
101108265(GRK2) 101117366(GRK3)
SSC: 
100156449(GRK3) 100513842(GRK2)
CFR: 
102505202(GRK3) 102523137(GRK2)
CDK: 
105099520(GRK3) 105104436(GRK2)
BACU: 
LVE: 
103073421(GRK3) 103076247(GRK2)
ECB: 
100059001(GRK2) 100065495(GRK3)
EPZ: 
103550032(GRK3) 103559830(GRK2)
EAI: 
106833505(GRK2) 106841709(GRK3)
MYB: 
102243341(GRK2) 102248143(GRK3)
MYD: 
102761774(GRK3) 102764962(GRK2)
HAI: 
109384296(GRK2) 109394134(GRK3)
RSS: 
109450370(GRK2) 109460327(GRK3)
PALE: 
102881239(GRK3) 102893733(GRK2)
LAV: 
100666578(GRK3) 100671884(GRK2)
MDO: 
100009844(GRK3)
SHR: 
100913578(GRK3)
OAA: 
GGA: 
416904(GRK3) 426000(GRK2)
MGP: 
100541374(GRK3) 100545380(GRK2)
CJO: 
107314190(GRK2) 107321443(GRK3)
APLA: 
101801089(ADRBK1) 101802877(GRK3)
ACYG: 
106029321(ADRBK1) 106031075(ADRBK2)
TGU: 
100217970(GRK3) 100227701(GRK2)
GFR: 
102032477(GRK2) 102036360(GRK3)
FAB: 
101810197(GRK3) 101811193(GRK2)
PHI: 
102108753(GRK3) 102114443(GRK2)
PMAJ: 
107205270(GRK2) 107211779(GRK3)
CCW: 
104688799(GRK3)
FPG: 
101911656(GRK2) 101916842(GRK3)
FCH: 
102048951(GRK3) 102058946(GRK2)
CLV: 
102092240(GRK2) 102096658(GRK3)
AAM: 
ASN: 
102367979(GRK2) 102378654(GRK3)
AMJ: 
102563874(GRK2) 106737118(GRK3)
PSS: 
102443539(GRK2) 102454375(ADRBK2)
CMY: 
102946005(GRK3) 102947181(GRK2)
CPIC: 
101944586(GRK2) 101953922(GRK3)
ACS: 
PVT: 
110083438(GRK3) 110085629(GRK2)
PBI: 
103064129(GRK2) 103066055(GRK3)
GJA: 
107116822(GRK2) 107123215(GRK3)
XLA: 
XTR: 
100379889(grk3)
NPR: 
DRE: 
569403(adrbk2)
SRX: 
SANH: 
SGH: 
IPU: 
108276813(ADRBK2)
TRU: 
101073064(grk3)
TNG: 
LCO: 
MZE: 
XMA: 
CSEM: 
103389928(grk3)
LCF: 
108895613(grk3)
HCQ: 
109527953(grk3)
BPEC: 
110166677(grk3)
SASA: 
ELS: 
105015221(grk3)
SFM: 
108930044(grk3)
LCM: 
102362780(GRK2) 102365333(ADRBK2)
CMK: 
BFO: 
CIN: 
100184862(adrbk2)
SPU: 
100888242(adrbk2)
SKO: 
DME: 
DAN: 
DER: 
DSE: 
DSI: 
Dsimw501_GD17695(Dsim_GD17695) Dsimw501_GD28815(Dsim_GD28815)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
413197(Gprk1)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
100166085(Gprk1)
DNX: 
PHU: 
DPX: 
ISC: 
TUT: 
CEL: 
CBR: 
CBG15249(Cbr-grk-2)
NAI: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
ADF: 
HMG: 
TAD: 
AQU: 
MBR: 
SRE: 
PTI: 
FCY: 
TPS: 
AAF: 
PIF: 
PSOJ: 
EHX: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9122168
  Authors
Daaka Y, Pitcher JA, Richardson M, Stoffel RH, Robishaw JD, Lefkowitz RJ
  Title
Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases.
  Journal
Proc Natl Acad Sci U S A 94:2180-5 (1997)
DOI:10.1073/pnas.94.6.2180
Reference
  Authors
Pao CS, Benovic JL
  Title
Structure/function analysis of alpha2A-adrenergic receptor interaction with G protein-coupled receptor kinase 2.
  Journal
J Biol Chem 280:11052-8 (2005)
DOI:10.1074/jbc.M412996200
  Sequence
[hsa:156]

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