KEGG ORTHOLOGY: K00910

ORTHOLOGY: K00910

Entry

K00910 KO

Name

ADRBK, GRK

Definition

beta-adrenergic-receptor kinase [EC:2.7.11.15]

Pathway

ko04062	Chemokine signaling pathway
ko04144	Endocytosis
ko04724	Glutamatergic synapse
ko04745	Phototransduction - fly
ko05032	Morphine addiction

Brite

KEGG Orthology (KO) [BR:ko00001]
Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
Organismal Systems
  Immune system
   04062 Chemokine signaling pathway
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
  Nervous system
   04724 Glutamatergic synapse
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
  Sensory system
   04745 Phototransduction - fly
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
Human Diseases
  Substance dependence
   05032 Morphine addiction
    K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.15  beta-adrenergic-receptor kinase
     K00910  ADRBK, GRK; beta-adrenergic-receptor kinase
Protein kinases [BR:ko01001]
Serine/threonine protein kinases: AGC group
  GRK family
   K00910  ADRBK, GRK; beta-adrenergic-receptor kinase

Other DBs

GO:

0047696

Genes

HSA:	156(ADRBK1) 157(ADRBK2)
PTR:	100614029(ADRBK2) 451363(ADRBK1)
PPS:	100984800(ADRBK2) 100991802(ADRBK1)
GGO:	101140574(ADRBK1) 101148325(ADRBK2)
PON:	100454669(ADRBK2) 100461893(ADRBK1)
MCC:	714510(ADRBK2) 721754(ADRBK1)
MMU:	110355(Adrbk1)
RNO:	25238(Adrbk1) 25372(Adrbk2)
CFA:	483701(ADRBK1) 486327(ADRBK2)
AML:	100469854 100475417
FCA:	101090393(ADRBK2) 101101082(ADRBK1)
BTA:	282136(ADRBK2) 282682(ADRBK1)
SSC:	100156449(ADRBK2) 100513842(ADRBK1)
ECB:	100059001 100065495(ADRBK2)
MDO:	100009844
SHR:	100913578(ADRBK2)
OAA:	100078284 100090102
GGA:	416904(ADRBK2) 426000(ADRBK1)
MGP:	100541374 100545380
TGU:	100217970(ADRBK2) 100227701(ADRBK1)
ACS:	100555775(adrbk1)
XTR:	100379889(adrbk2)
DRE:	569403(adrbk2)
TRU:	101073064
OLA:	101161494
BFO:	BRAFLDRAFT_218343
CIN:	100184862(adrbk2)
SPU:	100888242(adrbk2)
DME:	Dmel_CG40129(Gprk1)
DAN:	Dana_GF14814
DER:	Dere_GG16712
DSE:	Dsec_GM19330
DSI:	Dsim_GD17695
DWI:	Dwil_GK21377
DYA:	Dyak_GE25059
DGR:	Dgri_GH21712
DMO:	Dmoj_GI18854
DVI:	Dvir_GJ19694
AGA:	AgaP_AGAP012026
AAG:	AaeL_AAEL006868
CQU:	CpipJ_CPIJ004653 CpipJ_CPIJ004656
AME:	413197(Gprk1)
NVI:	100121113(NV12967)
TCA:	654946
API:	100166085(Gprk1)
PHU:	Phum_PHUM014910
ISC:	IscW_ISCW009785
CEL:	CELE_W02B3.2(grk-2)
CBR:	CBG15249(Cbr-grk-2)
TSP:	Tsp_00495
SMM:	Smp_159010.1
NVE:	NEMVE_v1g246204
HMG:	100214170
TAD:	TRIADDRAFT_59012
AQU:	100638292(Adrbk1)
MBR:	MONBRDRAFT_38629
PTI:	PHATRDRAFT_27639
TPS:	THAPSDRAFT_15351

» show all

Reference

PMID:9122168

Authors

Daaka Y, Pitcher JA, Richardson M, Stoffel RH, Robishaw JD, Lefkowitz RJ

Title

Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases.

Journal

Proc Natl Acad Sci U S A 94:2180-5 (1997)

All links

Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (107)   
   KEGG GENES (76)   
   KEGG DGENES (7)   
   KEGG EGENES (17)   
   KEGG MGENES (7)   
Protein sequence (43)   
   UniProt (43)   
Literature (1)   
   PubMed (1)   
All databases (166)   

Download RDF

DBGET integrated database retrieval system