KEGG   ORTHOLOGY: K01115Help
Entry
K01115                      KO                                     

Name
PLD1_2
Definition
phospholipase D1/2 [EC:3.1.4.4]
Pathway
ko00564  Glycerophospholipid metabolism
ko00565  Ether lipid metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko04014  Ras signaling pathway
ko04024  cAMP signaling pathway
ko04071  Sphingolipid signaling pathway
ko04072  Phospholipase D signaling pathway
ko04144  Endocytosis
ko04666  Fc gamma R-mediated phagocytosis
ko04724  Glutamatergic synapse
ko04912  GnRH signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00564 Glycerophospholipid metabolism
    K01115  PLD1_2; phospholipase D1/2
   00565 Ether lipid metabolism
    K01115  PLD1_2; phospholipase D1/2
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K01115  PLD1_2; phospholipase D1/2
   04072 Phospholipase D signaling pathway
    K01115  PLD1_2; phospholipase D1/2
   04071 Sphingolipid signaling pathway
    K01115  PLD1_2; phospholipase D1/2
   04024 cAMP signaling pathway
    K01115  PLD1_2; phospholipase D1/2
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K01115  PLD1_2; phospholipase D1/2
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    K01115  PLD1_2; phospholipase D1/2
  Endocrine system
   04912 GnRH signaling pathway
    K01115  PLD1_2; phospholipase D1/2
   04928 Parathyroid hormone synthesis, secretion and action
    K01115  PLD1_2; phospholipase D1/2
  Nervous system
   04724 Glutamatergic synapse
    K01115  PLD1_2; phospholipase D1/2
 Human Diseases
  Cancers
   05231 Choline metabolism in cancer
    K01115  PLD1_2; phospholipase D1/2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     K01115  PLD1_2; phospholipase D1/2
Membrane trafficking [BR:ko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    K01115  PLD1_2; phospholipase D1/2
 Endosome - Golgi transport
  Others
   Others
    K01115  PLD1_2; phospholipase D1/2
BRITE hierarchy
Other DBs
RN: R01310 R02051 R07385
GO: 0004630
Genes
HSA: 5337(PLD1) 5338(PLD2)
PTR: 454454(PLD2) 470996(PLD1)
PPS: 100984892(PLD1) 100985373(PLD2)
GGO: 101135150(PLD1) 101135996(PLD2)
PON: 100439813(PLD1) 100457163(PLD2)
NLE: 100601695(PLD2) 100605600(PLD1)
MCC: 694963(PLD1) 721573(PLD2)
MCF: 102130012(PLD2) 102132109(PLD1)
CSAB: 103221251(PLD1) 103242204(PLD2)
RRO: 104657174 104663087(PLD2) 104666985
RBB: 108524801(PLD2) 108525335 108540404(PLD1)
CJC: 100391217(PLD2) 100397093(PLD1)
SBQ: 101028583(PLD1) 101035480(PLD2)
MMU: 18805(Pld1) 18806(Pld2)
RNO: 25096(Pld1) 25097(Pld2)
CGE: 100689404(Pld1) 100752582(Pld2)
NGI: 103731722(Pld1) 103752195(Pld2)
HGL: 101700438(Pld1) 101713528(Pld2)
CCAN: 109684749(Pld2) 109694743(Pld1)
TUP: 102495205(PLD1) 102499889(PLD2)
CFA: 479473(PLD2) 488167(PLD1)
AML: 100477588(PLD2) 100484111(PLD1)
UMR: 103660447(PLD2) 103676145(PLD1)
ORO: 101369263(PLD1) 101383564(PLD2)
FCA: 101084052(PLD1) 101092214(PLD2)
PTG: 102962016(PLD1) 102971823(PLD2)
AJU: 106972398(PLD2) 106990052(PLD1)
BTA: 514554(PLD1) 522159(PLD2)
BOM: 102279771(PLD1) 102288325(PLD2)
BIU: 109558091(PLD1) 109574235(PLD2)
PHD: 102321950(PLD2) 102331547 102334692(PLD1)
CHX: 102174434(PLD1) 102176556(PLD2)
OAS: 101110687(PLD2) 101114661(PLD1)
SSC: 100519446(PLD1) 414900(PLD2)
CFR: 102505040(PLD1) 102520901(PLD2)
CDK: 105085948(PLD1) 105101475(PLD2)
BACU: 102999715(PLD1) 103008865(PLD2)
LVE: 103069742(PLD2) 103084538(PLD1)
OOR: 101278706(PLD2) 101284082(PLD1)
ECB: 100057774(PLD1) 100072863(PLD2)
EPZ: 103546360(PLD1) 103560664(PLD2)
EAI: 106844149(PLD2) 106847524(PLD1)
MYB: 102239050(PLD1) 102264100(PLD2)
MYD: 102756028(PLD1) 102760085(PLD2)
HAI: 109371666(PLD1) 109394696(PLD2)
PALE: 102884736(PLD1) 102894598(PLD2)
LAV: 100658318(PLD2) 100660595(PLD1)
MDO: 100009769(PLD1) 100618309(PLD2)
SHR: 100914579(PLD2) 100926651(PLD1) 111720053
GGA: 424986(PLD1)
MGP: 100547741(PLD1)
CJO: 107318313(PLD1)
APLA: 101802558(PLD1)
ACYG: 106031996(PLD1)
TGU: 100224050(PLD1)
GFR: 102038107(PLD1)
FAB: 101820022(PLD1)
PHI: 102101034(PLD1)
PMAJ: 107208899(PLD1)
CCW: 104688039(PLD1)
FPG: 101923489(PLD1)
FCH: 102052716(PLD1)
CLV: 102090500(PLD1)
EGZ: 104132470(PLD1)
ASN: 102371892(PLD1)
AMJ: 102573958(PLD1)
PSS: 102453139(PLD1) 102453375(PLD2)
CMY: 102945664(PLD1)
CPIC: 101931414(PLD1) 101939354
ACS: 100566734(pld1) 103282730
PVT: 110079069(PLD1) 110082332(PLD2)
PBI: 103048104(PLD2) 103062756(PLD1)
GJA: 107113860(PLD1) 107124417(PLD2)
XLA: 100191021(pld1.L) 108711785(pld2.L) 108718097
XTR: 100216200(pld2) 100379682(pld1)
NPR: 108784828(PLD1) 108800202
DRE: 556641(pld1a) 565743(pld2) 572492(pld1b) 799278(si:ch211-168k14.2)
LCO: 104920045(pld1) 104937282(pld2) 104938656
LCM: 102353212(PLD2) 102359218(PLD1)
CMK: 103189334(pld1) 103190576(pld2)
CIN: 100182057
APLC: 110987506
SKO: 100366642(PLD1)
DME: Dmel_CG12110(Pld)
DSI: Dsimw501_GD10404(Dsim_GD10404)
MDE: 101896559
AME: 725119(Pld)
BIM: 100742072
BTER: 100652186
SOC: 105201964
AEC: 105149246
ACEP: 105627094
PBAR: 105427752
HST: 105192308
CFO: 105254432
LHU: 105672039
PGC: 109854134
NVI: 100123116
TCA: 658196
DPA: 109544965
NVL: 108565175
BMOR: 101746390
ZNE: 110835596
FCD: 110858053
TUT: 107371515
CEL: CELE_C04G6.3(pld-1)
CBR: CBG02320(Cbr-pld-1)
BMY: Bm1_08640
TSP: Tsp_10708
CRG: 105332889
MYI: 110454166
OBI: 106868096
SHX: MS3_08230
EPA: 110241295
HMG: 100213342
ATH: AT1G52570(PLDALPHA2) AT1G55180(PLDEPSILON) AT2G42010(PLDBETA1) AT3G05630(PLDP2) AT3G15730(PLDALPHA1) AT3G16785(PLDP1) AT4G00240(PLDBETA2) AT4G11830(PLDGAMMA2) AT4G11840(PLDGAMMA3) AT4G11850(PLDGAMMA1) AT4G35790(PLDDELTA) AT5G25370(PLDALPHA3)
LJA: Lj0g3v0004479.1(Lj0g3v0004479.1) Lj0g3v0057229.1(Lj0g3v0057229.1) Lj0g3v0060819.1(Lj0g3v0060819.1) Lj0g3v0101819.1(Lj0g3v0101819.1) Lj0g3v0116389.1(Lj0g3v0116389.1) Lj0g3v0255459.1(Lj0g3v0255459.1) Lj0g3v0335969.1(Lj0g3v0335969.1) Lj0g3v0363499.1(Lj0g3v0363499.1) Lj1g3v1911660.1(Lj1g3v1911660.1) Lj1g3v1911690.1(Lj1g3v1911690.1) Lj1g3v2264770.1(Lj1g3v2264770.1) Lj2g3v1647880.1(Lj2g3v1647880.1) Lj2g3v1659550.1(Lj2g3v1659550.1) Lj2g3v2003100.1(Lj2g3v2003100.1) Lj3g3v0305820.1(Lj3g3v0305820.1) Lj3g3v2693190.1(Lj3g3v2693190.1) Lj4g3v2690740.1(Lj4g3v2690740.1) Lj5g3v1500430.1(Lj5g3v1500430.1) Lj6g3v1491480.1(Lj6g3v1491480.1) Lj6g3v1491490.1(Lj6g3v1491490.1)
POP: 7475119
VVI: 100232987(PLD) 100241982(PLDdelta2) 100250490(PLDbeta2) 100252422(PLDdelta) 100252995(PLDbeta1) 100256679(PLDepsilon) 100257647(PLDalpha3) 100259366(PLDalpha4) 100261019(PLDdelta1) 100261040(PLDalpha1) 100261987(PLDp) 104878268
DOSA: Os01t0172400-01(Os01g0172400) Os03t0119100-01(Os03g0119100) Os03t0391400-01(Os03g0391400) Os03t0840800-01(Os03g0840800) Os05t0171000-01(Os05g0171000) Os06t0604200-02(Os06g0604200) Os06t0604300-01(Os06g0604300) Os06t0604400-01(Os06g0604400) Os07t0260400-01(Os07g0260400) Os08t0401800-00(Os08g0401800) Os09t0421300-01(Os09g0421300) Os09t0543100-01(Os09g0543100) Os10t0524400-01(Os10g0524400)
ATS: 109735067(LOC109735067) 109735812(LOC109735812) 109738906(LOC109738906) 109745354(LOC109745354) 109752875(LOC109752875) 109757341(LOC109757341) 109761343(LOC109761343) 109761352(LOC109761352) 109761476(LOC109761476) 109763387(LOC109763387) 109763403(LOC109763403) 109765171(LOC109765171) 109768018(LOC109768018) 109771434(LOC109771434) 109773406(LOC109773406) 109777211(LOC109777211) 109780953(LOC109780953)
MNG: MNEG_3611
SCE: YKR031C(SPO14)
ERC: Ecym_6364
KMX: KLMA_40231(SPO14)
NCS: NCAS_0B07800(NCAS0B07800)
NDI: NDAI_0B05150(NDAI0B05150)
TPF: TPHA_0I00790(TPHA0I00790)
TBL: TBLA_0H02990(TBLA0H02990)
TDL: TDEL_0D01270(TDEL0D01270)
KAF: KAFR_0A03420(KAFR0A03420)
PIC: PICST_81277(SPO14)
CAL: CAALFM_C111590WA(PLD1)
CAUR: QG37_03448
SLB: AWJ20_2932(SPO14)
NTE: NEUTE1DRAFT132041(NEUTE1DRAFT_132041) NEUTE1DRAFT145274(NEUTE1DRAFT_145274) NEUTE1DRAFT78227(NEUTE1DRAFT_78227)
ANG: ANI_1_1734134(An15g07040) ANI_1_2596094(An11g11010) ANI_1_282064(An07g02240)
SPO: SPAC2F7.16c(pld1)
ABP: AGABI1DRAFT132820(AGABI1DRAFT_132820) AGABI1DRAFT58967(AGABI1DRAFT_58967)
ABV: AGABI2DRAFT186563(AGABI2DRAFT_186563) AGABI2DRAFT188389(AGABI2DRAFT_188389)
MGL: MGL_0321
DDI: DDB_G0277949(pldC) DDB_G0279483(pldB) DDB_G0281031(pldA)
DFA: DFA_08300(pldA) DFA_08480(pldB) DFA_10706(pldC)
EHI: EHI_082560(145.t00004) EHI_146550(350.t00005)
SMIN: v1.2.008765.t1(symbB.v1.2.008765.t1) v1.2.012415.t1(symbB.v1.2.012415.t1)
CTU: CTU_19640
RSL: RPSI07_mp0694(pld)
REH: H16_B0932(h16_B0932)
CTI: RALTA_B1035(pld2)
CARE: LT85_0735
DAR: Daro_0392
RLE: pRL120739
MEX: Mext_0106
RSP: RSP_0113
RDE: RD1_2477(pld)
RRU: Rru_A0202
MAV: MAV_3989
MVA: Mvan_5802
MGI: Mflv_1004
CTA: CTA_0306
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8530346
  Authors
Hammond SM, Altshuller YM, Sung TC, Rudge SA, Rose K, Engebrecht J, Morris AJ, Frohman MA
  Title
Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family.
  Journal
J Biol Chem 270:29640-3 (1995)
  Sequence
[hsa:5337]
Reference
  Authors
Speranza F, Mahankali M, Henkels KM, Gomez-Cambronero J
  Title
The molecular basis of leukocyte adhesion involving phosphatidic acid and phospholipase D.
  Journal
J Biol Chem 289:28885-97 (2014)
DOI:10.1074/jbc.M114.597146
  Sequence
[mmu:18805 18806]

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