| Entry |
|
| Name |
EPHX1
|
| Definition |
microsomal epoxide hydrolase [EC: 3.3.2.9]
|
| Pathway |
| Metabolism of xenobiotics by cytochrome P450 | | Bile secretion | | Chemical carcinogenesis |
|
| Disease |
| Isolated orofacial clefts |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
Metabolism
Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
K01253 EPHX1; microsomal epoxide hydrolase
Organismal Systems
Digestive system
04976 Bile secretion
K01253 EPHX1; microsomal epoxide hydrolase
Human Diseases
Cancers
05204 Chemical carcinogenesis
K01253 EPHX1; microsomal epoxide hydrolase
Enzymes [BR:ko01000]
3. Hydrolases
3.3 Acting on ether bonds
3.3.2 Ether hydrolases
3.3.2.9 microsomal epoxide hydrolase
K01253 EPHX1; microsomal epoxide hydrolase
 |
| Other DBs |
|
| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | CIN: | | SPU: | | CEL: | | CBR: | | BMY: | | TSP: | | NVE: | | TAD: | | PIC: | | MGR: | | ANI: | | AFM: | | ANG: | | CNE: | | UMA: | | REH: | | BUR: | | PUB: | | BRA: | | BBT: | | HNE: | | GBE: | | BCL: | | MBB: | | MSM: | | AAU: | | FRA: | | FAL: | | SEN: | | STP: | | » show all
   |
| Reference |
|
| Authors |
von Dippe P, Zhu QS, Levy D |
| Title |
Cell surface expression and bile acid transport function of one topological form of m-epoxide hydrolase. |
| Journal |
Biochem Biophys Res Commun 309:804-9 (2003) |
| Reference |
|
| Authors |
Decker M, Arand M, Cronin A |
| Title |
Mammalian epoxide hydrolases in xenobiotic metabolism and signalling. |
| Journal |
Arch Toxicol 83:297-318 (2009) |