KEGG   ORTHOLOGY: K01253Help
Entry
K01253                      KO                                     

Name
EPHX1
Definition
microsomal epoxide hydrolase [EC:3.3.2.9]
Pathway
Metabolism of xenobiotics by cytochrome P450
Bile secretion
Chemical carcinogenesis
Disease
H00516  
Isolated orofacial clefts
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K01253  EPHX1; microsomal epoxide hydrolase
 Organismal Systems
  Digestive system
   04976 Bile secretion
    K01253  EPHX1; microsomal epoxide hydrolase
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K01253  EPHX1; microsomal epoxide hydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.9  microsomal epoxide hydrolase
     K01253  EPHX1; microsomal epoxide hydrolase
BRITE hierarchy
Other DBs
Genes
HSA: 
2052(EPHX1)
PTR: 
457777(EPHX1)
PPS: 
100995858(EPHX1)
GGO: 
101130068(EPHX1)
PON: 
100173792(EPHX1)
MCC: 
700180(EPHX1)
MCF: 
MMU: 
13849(Ephx1)
RNO: 
25315(Ephx1)
CGE: 
HGL: 
101725522(Ephx1)
TUP: 
102495357(EPHX1)
CFA: 
480113(EPHX1)
AML: 
100477671(EPHX1)
FCA: 
101085519(EPHX1)
PTG: 
102949568(EPHX1)
BTA: 
535293(EPHX1)
BOM: 
102267623(EPHX1)
PHD: 
102316040(EPHX1)
CHX: 
100860945(EPHX1)
SSC: 
397639(EPHX1)
CFR: 
102519415(EPHX1)
ECB: 
100054269(EPHX1)
MYB: 
102263401(EPHX1)
MYD: 
102767193(EPHX1)
PALE: 
102883919(EPHX1)
MDO: 
100025778(EPHX1)
SHR: 
100925093(EPHX1)
OAA: 
100081956(EPHX1)
GGA: 
421321(EPHX1) 421447
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
101914944(EPHX1)
FCH: 
102059804(EPHX1)
CLV: 
102085632(EPHX1)
ASN: 
102368835(EPHX1)
PSS: 
102457257(EPHX1)
ACS: 
XLA: 
432100(ephx1)
XTR: 
100158543(ephx1)
DRE: 
394043(ephx1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102353239(EPHX1)
BFO: 
CIN: 
SPU: 
CEL: 
CELE_W01A11.1(W01A11.1)
CBR: 
BMY: 
LOA: 
TSP: 
NVE: 
TAD: 
PIC: 
MGR: 
ANI: 
AFM: 
ANG: 
ANI_1_312144(An16g02170)
CNE: 
UMA: 
REH: 
H16_A1767(h16_A1767) H16_A1793(h16_A1793)
BUR: 
BRA: 
BBT: 
HNE: 
GBE: 
PUB: 
SAR11_0803(ephX1)
BCL: 
MBB: 
BCG_1185(ephC) BCG_1977(ephB) BCG_3200c(mesTb) BCG_3201c(mesTa) BCG_3728(ephE)
MSM: 
AAU: 
FRA: 
FAL: 
SEN: 
STP: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
von Dippe P, Zhu QS, Levy D
  Title
Cell surface expression and bile acid transport function of one topological form  of m-epoxide hydrolase.
  Journal
Biochem Biophys Res Commun 309:804-9 (2003)
Reference
  Authors
Decker M, Arand M, Cronin A
  Title
Mammalian epoxide hydrolases in xenobiotic metabolism and signalling.
  Journal
Arch Toxicol 83:297-318 (2009)

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