KEGG   ORTHOLOGY: K01253Help
Entry
K01253                      KO                                     

Name
EPHX1
Definition
microsomal epoxide hydrolase [EC:3.3.2.9]
Pathway
ko00980  Metabolism of xenobiotics by cytochrome P450
ko04976  Bile secretion
ko05204  Chemical carcinogenesis
Disease
H00516  Cleft lip and/or cleft palate
H01935  Familial hypercholanemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K01253  EPHX1; microsomal epoxide hydrolase
 Organismal Systems
  Digestive system
   04976 Bile secretion
    K01253  EPHX1; microsomal epoxide hydrolase
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K01253  EPHX1; microsomal epoxide hydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.9  microsomal epoxide hydrolase
     K01253  EPHX1; microsomal epoxide hydrolase
Peptidases [BR:ko01002]
 Serine Peptidases
  Family S33
   K01253  EPHX1; microsomal epoxide hydrolase
BRITE hierarchy
Other DBs
RN: R07013 R07014 R07027 R07071 R07072 R07082 R09410 R09417 R09443
COG: COG0596
GO: 0004301
Genes
HSA: 2052(EPHX1)
PTR: 457777(EPHX1)
PPS: 100995858(EPHX1)
GGO: 101130068(EPHX1)
PON: 100173792(EPHX1)
NLE: 100592261
MCC: 700180(EPHX1)
MCF: 101866419(EPHX1)
CSAB: 103230002(EPHX1)
RRO: 104660094
RBB: 108538734(EPHX1)
CJC: 100409580(EPHX1)
SBQ: 101029266(EPHX1)
MMU: 13849(Ephx1)
RNO: 25315(Ephx1)
CGE: 100758590
HGL: 101725522(Ephx1)
CCAN: 109691483
OCU: 100009104(EPHX1)
TUP: 102495357(EPHX1)
CFA: 480113(EPHX1)
AML: 100477671(EPHX1)
UMR: 103669061(EPHX1)
ORO: 101368385(EPHX1)
FCA: 101085519(EPHX1)
PTG: 102949568(EPHX1)
AJU: 106968617(EPHX1)
BTA: 535293(EPHX1)
BOM: 102267623(EPHX1)
BIU: 109570425(EPHX1)
PHD: 102316040(EPHX1)
CHX: 100860945(EPHX1)
OAS: 101111038(EPHX1)
SSC: 397639(EPHX1)
CFR: 102519415(EPHX1)
CDK: 105099693(EPHX1)
BACU: 103003233(EPHX1)
LVE: 103074317(EPHX1)
OOR: 101288139(EPHX1)
ECB: 100054269(EPHX1)
EPZ: 103543505(EPHX1)
EAI: 106844729(EPHX1)
MYB: 102263401(EPHX1)
MYD: 102767193(EPHX1)
HAI: 109391461(EPHX1)
RSS: 109446996(EPHX1)
PALE: 102883919(EPHX1)
LAV: 100673770(EPHX1)
TMU: 101360751
MDO: 100025778(EPHX1)
SHR: 100925093(EPHX1)
OAA: 100081956(EPHX1)
GGA: 421321(EPHX1) 421447(EPHX1L)
MGP: 100539493 100545721(EPHX1)
CJO: 107311037(EPHX1) 107311272
APLA: 101790722 101801005(EPHX1)
ACYG: 106031535(EPHX1)
TGU: 100222959(EPHX1) 100227392
GFR: 102041759(EPHX1) 102042334
FAB: 101806940(EPHX1) 101814529
PHI: 102100615 102109472(EPHX1)
PMAJ: 107201817(EPHX1)
CCW: 104684354 104685565(EPHX1)
FPG: 101912868 101914944(EPHX1)
FCH: 102050687 102059804(EPHX1)
CLV: 102085632(EPHX1) 102092641
EGZ: 104134609(EPHX1)
AAM: 106482713(EPHX1) 106485556
ASN: 102368835(EPHX1) 102386213
AMJ: 102571832 102577262(EPHX1)
PSS: 102456152 102457257(EPHX1)
CMY: 102934448(EPHX1) 102942209
CPIC: 101936865(EPHX1) 101949762
ACS: 100554472 100555586(ephx1)
PVT: 110075401(EPHX1)
PBI: 103058096(EPHX1)
GJA: 107119060(EPHX1)
XLA: 108716563 432100(ephx1.L)
XTR: 100158543(ephx1)
NPR: 108787057(EPHX1)
DRE: 394043(ephx1)
SRX: 107732537
SANH: 107690044(ephx1)
SGH: 107601524
CCAR: 109080243
IPU: 108263372(ephx1)
AMEX: 103040834(ephx1)
TRU: 101066103(ephx1)
LCO: 104918259 104918311(ephx1)
NCC: 104963447(ephx1)
MZE: 101463752 101487605(ephx1)
OLA: 101166982 101172051(ephx1)
XMA: 102229129 102230310(ephx1)
PRET: 103477226
NFU: 107375461
CSEM: 103380678(ephx1)
LCF: 108901766(ephx1)
HCQ: 109516170
BPEC: 110154206(ephx1)
ELS: 105017773(ephx1)
SFM: 108925178(ephx1)
LCM: 102353239(EPHX1)
CMK: 103181611
CIN: 100176449
SPU: 588166
APLC: 110978249
SKO: 100371948
TUT: 107364002
CEL: CELE_W01A11.1(W01A11.1)
CBR: CBG18950
BMY: Bm1_48070
TSP: Tsp_04403
LAK: 106154062
EPA: 110242247
PIC: PICST_38202(SEH1)
ANI: AN3017.2
ANG: ANI_1_312144(An16g02170)
CNE: CNN02220
HNE: HNE_2052
PUB: SAR11_0803(ephX1)
BCL: ABC1387
MBB: BCG_1185(ephC) BCG_1977(ephB) BCG_3200c(mesTb) BCG_3201c(mesTa) BCG_3728(ephE)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
von Dippe P, Zhu QS, Levy D
  Title
Cell surface expression and bile acid transport function of one topological form of m-epoxide hydrolase.
  Journal
Biochem Biophys Res Commun 309:804-9 (2003)
DOI:10.1016/j.bbrc.2003.08.074
Reference
  Authors
Decker M, Arand M, Cronin A
  Title
Mammalian epoxide hydrolases in xenobiotic metabolism and signalling.
  Journal
Arch Toxicol 83:297-318 (2009)
DOI:10.1007/s00204-009-0416-0

DBGET integrated database retrieval system