KEGG   ORTHOLOGY: K01365Help
Entry
K01365                      KO                                     

Name
CTSL
Definition
cathepsin L [EC:3.4.22.15]
Pathway
Lysosome
Phagosome
Antigen processing and presentation
Proteoglycans in cancer
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K01365  CTSL; cathepsin L
   04142 Lysosome
    K01365  CTSL; cathepsin L
 Organismal Systems
  Immune system
   04612 Antigen processing and presentation
    K01365  CTSL; cathepsin L
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K01365  CTSL; cathepsin L
  Immune diseases
   05323 Rheumatoid arthritis
    K01365  CTSL; cathepsin L
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.15  cathepsin L
     K01365  CTSL; cathepsin L
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C1: papain family
   K01365  CTSL; cathepsin L
Chaperones and folding catalysts [BR:ko03110]
 Intramolecular chaperones
  Papain family
   K01365  CTSL; cathepsin L
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
1514(CTSL)
PTR: 
737449(CTSL1)
PPS: 
100987260(CTSL1)
GGO: 
PON: 
100450374(CTSL1)
MCC: 
MCF: 
MMU: 
13039(Ctsl)
RNO: 
25697(Ctsl)
CGE: 
HGL: 
TUP: 
CFA: 
AML: 
FCA: 
PTG: 
BTA: 
281108(CTSV) 515200(CTSL1)
BOM: 
PHD: 
CHX: 
OAS: 
780510(CTSL2)
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
420160 427466(CTSL2)
MGP: 
TGU: 
FAB: 
101814636(CTSL)
PHI: 
102099328(CTSL)
APLA: 
101803168(CTSL1)
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
100561941(ctsl)
PBI: 
XLA: 
447313(ctsv)
XTR: 
448179(ctsv)
DRE: 
30443(ctsl1b) 321453(ctsla)
TRU: 
MZE: 
OLA: 
100049246(ctsl)
XMA: 
LCM: 
CMK: 
103188176(ctsl)
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
552756(GB19923)
NVI: 
BMOR: 
693031(Bcp)
API: 
100166071(Ctsl)
PHU: 
CEL: 
CBR: 
CBG22599(Cbr-cpl-1)
BMY: 
LOA: 
NVE: 
HMG: 
TAD: 
AQU: 
MTR: 
OLU: 
OTA: 
MBR: 
DDI: 
DPP: 
EDI: 
ACAN: 
TET: 
PTI: 
TPS: 
GTT: 
TVA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3342889
  Authors
Ritonja A, Popovic T, Kotnik M, Machleidt W, Turk V
  Title
Amino acid sequences of the human kidney cathepsins H and L.
  Journal
FEBS Lett 228:341-5 (1988)
Reference
  Authors
Hook V, Yasothornsrikul S, Greenbaum D, Medzihradszky KF, Troutner K, Toneff T, Bundey R, Logrinova A, Reinheckel T, Peters C, Bogyo M
  Title
Cathepsin L and Arg/Lys aminopeptidase: a distinct prohormone processing pathway  for the biosynthesis of peptide neurotransmitters and hormones.
  Journal
Biol Chem 385:473-80 (2004)

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