KEGG   ORTHOLOGY: K01370Help
Entry
K01370                      KO                                     

Name
CASP1
Definition
caspase 1 [EC:3.4.22.36]
Pathway
NOD-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Legionellosis
Influenza A
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04621 NOD-like receptor signaling pathway
    K01370  CASP1; caspase 1
   04623 Cytosolic DNA-sensing pathway
    K01370  CASP1; caspase 1
 Human Diseases
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    K01370  CASP1; caspase 1
  Infectious diseases
   05132 Salmonella infection
    K01370  CASP1; caspase 1
   05133 Pertussis
    K01370  CASP1; caspase 1
   05134 Legionellosis
    K01370  CASP1; caspase 1
   05164 Influenza A
    K01370  CASP1; caspase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.36  caspase-1
     K01370  CASP1; caspase 1
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C14: caspase family
   K01370  CASP1; caspase 1
BRITE hierarchy
Genes
HSA: 
834(CASP1)
PTR: 
101058924(CASP1)
PPS: 
100985633(CARD17) 100985973 100986637(CARD16)
GGO: 
101136563(CASP1)
PON: 
100437679(CASP1)
NLE: 
100588974(CASP1)
MCC: 
706568(CASP1)
MCF: 
102118885(CASP1)
CSAB: 
RRO: 
CJC: 
100385618(CASP1)
SBQ: 
MMU: 
12362(Casp1)
RNO: 
25166(Casp1)
CGE: 
100759171(Casp1)
NGI: 
103743236(Casp1)
HGL: 
101725179(Casp1)
OCU: 
100101588(CASP1)
TUP: 
102490614(CASP1)
BTA: 
514214(CASP1)
PHD: 
OAS: 
SSC: 
397319(CASP1)
CFR: 
BACU: 
LVE: 
ECB: 
100033888(CASP1)
MYB: 
MYD: 
LAV: 
MDO: 
SHR: 
OAA: 
GGA: 
395764(CASP1)
MGP: 
CJO: 
APLA: 
101789899(CASP1)
FPG: 
FCH: 
CLV: 
AAM: 
ASN: 
AMJ: 
102575910(CASP1) 106738110(CARD18)
PSS: 
CMY: 
ACS: 
PBI: 
GJA: 
XLA: 
378669(casp1.S) 397719(casp1.L)
XTR: 
100491605(casp1)
DRE: 
57933(caspa)
TRU: 
TNG: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
CMK: 
103180499(caspase-1)
VG: 
26281673(ATL82_gp041) 28218312(ORF67) 28619903(BGV90_gp043) 2947764(FV3gorf64R) 3678208(ATVp41)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
PMID:7780029
  Authors
Keane KM, Giegel DA, Lipinski WJ, Callahan MJ, Shivers BD
  Title
Cloning, tissue expression and regulation of rat interleukin 1 beta converting enzyme.
  Journal
Cytokine 7:105-10 (1995)
  Sequence
[rno:25166]
Reference
PMID:1373520
  Authors
Cerretti DP, Kozlosky CJ, Mosley B, Nelson N, Van Ness K, Greenstreet TA, March CJ, Kronheim SR, Druck T, Cannizzaro LA, et al.
  Title
Molecular cloning of the interleukin-1 beta converting enzyme.
  Journal
Science 256:97-100 (1992)
  Sequence
[hsa:834]

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