KEGG   ORTHOLOGY: K01370Help
Entry
K01370                      KO                                     

Name
CASP1
Definition
caspase 1 [EC:3.4.22.36]
Pathway
NOD-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Legionellosis
Influenza A
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04621 NOD-like receptor signaling pathway
    K01370  CASP1; caspase 1
   04623 Cytosolic DNA-sensing pathway
    K01370  CASP1; caspase 1
 Human Diseases
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    K01370  CASP1; caspase 1
  Infectious diseases
   05132 Salmonella infection
    K01370  CASP1; caspase 1
   05133 Pertussis
    K01370  CASP1; caspase 1
   05134 Legionellosis
    K01370  CASP1; caspase 1
   05164 Influenza A
    K01370  CASP1; caspase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.36  caspase-1
     K01370  CASP1; caspase 1
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C14: caspase family
   K01370  CASP1; caspase 1
BRITE hierarchy
Genes
HSA: 
834(CASP1)
PTR: 
PPS: 
100986637(CASP1)
GGO: 
101136563(CASP1)
PON: 
100437679(CASP1)
MCC: 
706568(CASP1)
MCF: 
102118885(CASP1)
MMU: 
12362(Casp1)
RNO: 
25166(Casp1)
CGE: 
100759171(Casp1)
HGL: 
101725179(Casp1)
TUP: 
FCA: 
493961(CASP1)
BTA: 
514214(CASP1)
BOM: 
PHD: 
CHX: 
SSC: 
397319(CASP1)
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
395764(CASP1)
MGP: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
XLA: 
378669(casp1-b) 397719(casp1-a)
XTR: 
DRE: 
57933(caspa)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7780029
  Authors
Keane KM, Giegel DA, Lipinski WJ, Callahan MJ, Shivers BD
  Title
Cloning, tissue expression and regulation of rat interleukin 1 beta converting enzyme.
  Journal
Cytokine 7:105-10 (1995)
Reference
  Authors
Sakamaki K, Satou Y
  Title
Caspases: evolutionary aspects of their functions in vertebrates.
  Journal
J Fish Biol 74:727-53 (2009)
Reference
  Authors
Chowdhury I, Tharakan B, Bhat GK
  Title
Caspases - an update.
  Journal
Comp Biochem Physiol B Biochem Mol Biol 151:10-27 (2008)

DBGET integrated database retrieval system