KEGG ORTHOLOGY: K01388

ORTHOLOGY: K01388

Entry

K01388 KO

Name

MMP1

Definition

matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]

Pathway

ko03320	PPAR signaling pathway
ko05200	Pathways in cancer
ko05219	Bladder cancer
ko05323	Rheumatoid arthritis

Disease

H00028

Choriocarcinoma

Brite

KEGG Orthology (KO) [BR:ko00001]
Organismal Systems
  Endocrine system
   03320 PPAR signaling pathway
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Human Diseases
  Cancers
   05200 Pathways in cancer
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
   05219 Bladder cancer
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
  Immune diseases
   05323 Rheumatoid arthritis
    K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.7  interstitial collagenase
     K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Peptidases [BR:ko01002]
Metallo Peptidases
  Family M10
   K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase)
Cell adhesion molecules and their ligands [BR:ko04516]
2. Integrin Family
  Beta1 integrins
   VLA-2
    ITGB1; integrin beta 1
     K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase)

Other DBs

GO:

0008133

Genes

HSA:	4312(MMP1)
PTR:	451510(MMP1)
PPS:	100995251
GGO:	101131051(MMP1)
PON:	100459931(MMP1)
MCC:	703653(MMP1)
MMU:	83995(Mmp1a) 83996(Mmp1b)
RNO:	300338(Mmp1b) 300339(Mmp1)
CFA:	489428(MMP1)
AML:	100478167
FCA:	101084217
BTA:	100848085 281308(MMP1)
SSC:	397320(MMP1)
ECB:	100033896(MMP1)
MDO:	100012472(MMP1)
SHR:	100915062(MMP1)
OAA:	100078975
GGA:	418982(MMP1)
MGP:	100543241
TGU:	100218575(MMP1)
ACS:	100552848
XLA:	495287(mmp1)
XTR:	594916(mmp1)

» show all

Reference

PMID:19631700

Authors

Fanjul-Fernandez M, Folgueras AR, Cabrera S, Lopez-Otin C

Title

Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models.

Journal

Biochim Biophys Acta 1803:3-19 (2010)

Reference

PMID:18060181

Authors

Amalinei C, Caruntu ID, Balan RA

Title

Biology of metalloproteinases.

Journal

Rom J Morphol Embryol 48:323-34 (2007)

All links

Ontology (7)   
   KEGG BRITE (6)   
   GO (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (37)   
   KEGG GENES (26)   
   KEGG EGENES (9)   
   KEGG MGENES (2)   
Protein sequence (18)   
   UniProt (18)   
Literature (2)   
   PubMed (2)   
All databases (75)   

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