KEGG   ORTHOLOGY: K01389Help
Entry
K01389                      KO                                     
Name
MME
Definition
neprilysin [EC:3.4.24.11]
Pathway
Renin-angiotensin system
Hematopoietic cell lineage
Protein digestion and absorption
Alzheimer's disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K01389  MME; neprilysin
  Endocrine system
   04614 Renin-angiotensin system
    K01389  MME; neprilysin
  Digestive system
   04974 Protein digestion and absorption
    K01389  MME; neprilysin
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K01389  MME; neprilysin
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.11  neprilysin
     K01389  MME; neprilysin
Peptidases [BR:ko01002]
 Metallo Peptidases
  Family M13: neprilysin family
   K01389  MME; neprilysin
Cellular antigens [BR:ko04090]
 Proteins
  K01389  CD10, MME; membrane metallo-endopeptidase
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
4311(MME)
PTR: 
460792(MME)
PPS: 
GGO: 
PON: 
MCC: 
707667(MME)
MMU: 
17380(Mme)
RNO: 
24590(Mme)
CFA: 
477120(MME)
AML: 
FCA: 
101087516(MME)
BTA: 
536741(MME)
SSC: 
100511536(MME)
ECB: 
100053541(MME)
MDO: 
100012497
SHR: 
100920293(MME)
OAA: 
100075251 100092983
GGA: 
425031(MME)
MGP: 
100544190
TGU: 
100224600(MME)
ACS: 
100558527
OLA: 
101170860
BFO: 
BRAFLDRAFT_278852
CEL: 
CELE_F26G1.6(nep-12)
MVA: 
Mvan_0184
MGI: 
Mflv_0472
MMC: 
Mmcs_0157
MKM: 
Mkms_0166
MJL: 
Mjls_0147
RHA: 
RHA1_ro05118
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Miners JS, Baig S, Palmer J, Palmer LE, Kehoe PG, Love S
  Title
Abeta-degrading enzymes in Alzheimer's disease.
  Journal
Brain Pathol 18:240-52 (2008)
Reference
PMID:7937532
  Authors
Bai JP
  Title
Distribution of brush-border membrane peptidases along the rat intestine.
  Journal
Pharm Res 11:897-900 (1994)
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