KEGG   ORTHOLOGY: K01403Help
Entry
K01403                      KO                                     
Name
MMP9
Definition
matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
Pathway
Leukocyte transendothelial migration
Estrogen signaling pathway
Hepatitis B
Pathways in cancer
Transcriptional misregulation in cancer
Proteoglycans in cancer
Bladder cancer
Disease
H00025  
Penile cancer
H00479  
Metaphyseal dysplasias
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
  Endocrine system
   04915 Estrogen signaling pathway
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
   05202 Transcriptional misregulation in cancers
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
   05205 Proteoglycans in cancer
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
   05219 Bladder cancer
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
  Infectious diseases
   05161 Hepatitis B
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.35  gelatinase B
     K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
Peptidases [BR:ko01002]
 Metallo Peptidases
  Family M10
   K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
BRITE hierarchy
Genes
HSA: 
4318(MMP9)
PTR: 
458294(MMP9)
PPS: 
100974722(MMP9)
GGO: 
101138361(MMP9)
PON: 
100455867(MMP9)
MCC: 
708084(MMP9)
MMU: 
17395(Mmp9)
RNO: 
81687(Mmp9)
CFA: 
403885(MMP9)
AML: 
FCA: 
101084185(MMP9)
BTA: 
282871(MMP9)
SSC: 
654325(MMP9)
ECB: 
100056599(MMP9)
MDO: 
100022144
SHR: 
100934566(MMP9)
GGA: 
395387(MMP9)
MGP: 
100540313
TGU: 
100227728(MMP9)
XLA: 
100037129(mmp-9th) 379663(mmp9)
XTR: 
100494738 448591(mmp9)
DRE: 
406397(mmp9)
TRU: 
653023(mmp-9)
OLA: 
100125420(gel-b)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Fanjul-Fernandez M, Folgueras AR, Cabrera S, Lopez-Otin C
  Title
Matrix metalloproteinases: evolution, gene regulation and functional analysis in  mouse models.
  Journal
Biochim Biophys Acta 1803:3-19 (2010)
Reference
  Authors
Amalinei C, Caruntu ID, Balan RA
  Title
Biology of metalloproteinases.
  Journal
Rom J Morphol Embryol 48:323-34 (2007)
Reference
  Authors
Hua H, Li M, Luo T, Yin Y, Jiang Y
  Title
Matrix metalloproteinases in tumorigenesis: an evolving paradigm.
  Journal
Cell Mol Life Sci 68:3853-68 (2011)
DBGET integrated database retrieval system