KEGG   ORTHOLOGY: K01403Help
Entry
K01403                      KO                                     

Name
MMP9
Definition
matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
Pathway
TNF signaling pathway
Leukocyte transendothelial migration
Estrogen signaling pathway
Hepatitis B
Pathways in cancer
Transcriptional misregulation in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Bladder cancer
Disease
H00025  
Penile cancer
H00479  
Metaphyseal dysplasias
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04668 TNF signaling pathway
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
 Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
  Endocrine system
   04915 Estrogen signaling pathway
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
   05202 Transcriptional misregulation in cancers
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
   05206 MicroRNAs in cancer
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
   05205 Proteoglycans in cancer
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
   05219 Bladder cancer
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
  Infectious diseases
   05161 Hepatitis B
    K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.35  gelatinase B
     K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
Peptidases [BR:ko01002]
 Metallo Peptidases
  Family M10
   K01403  MMP9; matrix metalloproteinase-9 (gelatinase B)
BRITE hierarchy
Genes
HSA: 
4318(MMP9)
PTR: 
458294(MMP9)
PPS: 
100974722(MMP9)
GGO: 
101138361(MMP9)
PON: 
100455867(MMP9)
MCC: 
708084(MMP9)
MCF: 
102117693(MMP9)
MMU: 
17395(Mmp9)
RNO: 
81687(Mmp9)
CGE: 
100770707(Mmp9)
HGL: 
101717243(Mmp9)
TUP: 
102487885(MMP9)
CFA: 
403885(MMP9)
AML: 
FCA: 
101084185(MMP9)
BTA: 
282871(MMP9)
BOM: 
102273141(MMP9)
PHD: 
102321866(MMP9)
CHX: 
102168469(MMP9)
SSC: 
654325(MMP9)
CFR: 
102509767(MMP9)
ECB: 
100056599(MMP9)
MYB: 
102260281(MMP9)
MDO: 
SHR: 
100934566(MMP9)
GGA: 
395387(MMP9)
MGP: 
TGU: 
100227728(MMP9)
FAB: 
101813444(MMP9)
PHI: 
102112681(MMP9)
APLA: 
101793782(MMP9)
FPG: 
101912755(MMP9)
FCH: 
102053895(MMP9)
CLV: 
102094215(MMP9)
ASN: 
102368987(MMP9)
XLA: 
100037129(mmp-9th) 379663(mmp9)
XTR: 
DRE: 
406397(mmp9)
TRU: 
653023(mmp-9)
MZE: 
OLA: 
100125420(gel-b)
XMA: 
LCM: 
102358076(MMP9)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Fanjul-Fernandez M, Folgueras AR, Cabrera S, Lopez-Otin C
  Title
Matrix metalloproteinases: evolution, gene regulation and functional analysis in  mouse models.
  Journal
Biochim Biophys Acta 1803:3-19 (2010)
Reference
  Authors
Amalinei C, Caruntu ID, Balan RA
  Title
Biology of metalloproteinases.
  Journal
Rom J Morphol Embryol 48:323-34 (2007)
Reference
  Authors
Hua H, Li M, Luo T, Yin Y, Jiang Y
  Title
Matrix metalloproteinases in tumorigenesis: an evolving paradigm.
  Journal
Cell Mol Life Sci 68:3853-68 (2011)

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