KEGG   ORTHOLOGY: K01825Help
Entry
K01825                      KO                                     

Name
fadB
Definition
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
Pathway
Fatty acid degradation
Valine, leucine and isoleucine degradation
Geraniol degradation
Lysine degradation
Tryptophan metabolism
beta-Alanine metabolism
Propanoate metabolism
Butanoate metabolism
Carbon fixation pathways in prokaryotes
Limonene and pinene degradation
Caprolactam degradation
Biosynthesis of unsaturated fatty acids
Carbon metabolism
Fatty acid metabolism
Module
M00032  
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00087  
beta-Oxidation
M00374  
Dicarboxylate-hydroxybutyrate cycle
M00375  
Hydroxypropionate-hydroxybutylate cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
   01212 Fatty acid metabolism
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  Carbohydrate metabolism
   00640 Propanoate metabolism
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
   00650 Butanoate metabolism
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  Energy metabolism
   00720 Carbon fixation pathways in prokaryotes
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  Lipid metabolism
   00071 Fatty acid degradation
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
   01040 Biosynthesis of unsaturated fatty acids
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
   00310 Lysine degradation
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
   00380 Tryptophan metabolism
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  Metabolism of terpenoids and polyketides
   00903 Limonene and pinene degradation
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
   00281 Geraniol degradation
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  Xenobiotics biodegradation and metabolism
   00930 Caprolactam degradation
    K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
KEGG modules [BR:ko00002]
 Pathway module
  Energy metabolism
   Carbon fixation
    M00375  Hydroxypropionate-hydroxybutylate cycle
     K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
    M00374  Dicarboxylate-hydroxybutyrate cycle
     K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  Carbohydrate and lipid metabolism
   Fatty acid metabolism
    M00087  beta-Oxidation
     K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  Nucleotide and amino acid metabolism
   Lysine metabolism
    M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
     K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.35  3-hydroxyacyl-CoA dehydrogenase
     K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17  enoyl-CoA hydratase
     K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.2  Acting on hydroxy acids and derivatives
    5.1.2.3  3-hydroxybutyryl-CoA epimerase
     K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.8  dodecenoyl-CoA isomerase
     K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
BRITE hierarchy
Other DBs
Genes
ECO: 
b3846(fadB)
ECJ: 
Y75_p3334(fadB)
ECD: 
EBW: 
BWG_3522(fadB)
ECOK: 
ECE: 
Z5367(fadB)
ECS: 
ECs4774(fadB)
ECF: 
ETW: 
ECSP_4899(fadB)
ELX: 
EOJ: 
EOI: 
EOH: 
ECG: 
EOK: 
ELR: 
ECC: 
c4793(fadB)
ECP: 
ECP_4059(fadB)
ECI: 
ECV: 
ECX: 
ECW: 
ECM: 
ECY: 
ECSE_4132(fadB)
ECR: 
ECQ: 
ECK: 
ECT: 
EOC: 
CE10_4505(fadB)
EUM: 
ECZ: 
ELO: 
ELN: 
ELH: 
ESE: 
ESO: 
O3O_00700(fadB)
ESM: 
O3M_24555(fadB)
ESL: 
O3K_24635(fadB)
ECL: 
EBR: 
ECB_03737(fadB)
EBD: 
ECBD_4179(fadB)
EKO: 
EKF: 
EAB: 
EDH: 
EDJ: 
EIH: 
ENA: 
ELU: 
EUN: 
ELW: 
ECW_m4146(fadB)
ELL: 
WFL_20230(fadB)
ELC: 
i14_4387(fadB)
ELD: 
i02_4387(fadB)
ELP: 
EBL: 
ECD_03737(fadB)
EBE: 
B21_03686(fadB)
ELF: 
LF82_0614(fadB)
ECOA: 
ECOL: 
ECOI: 
ECOJ: 
ECOO: 
ECOH: 
EFE: 
EFER_3635(fadB)
STY: 
STY3577(fadB)
STT: 
t3315(fadB)
SEX: 
SENT: 
STM: 
STM3983(fadB)
SEO: 
SEV: 
SEY: 
SEM: 
SEJ: 
SEB: 
SEF: 
SETU: 
SETC: 
SEEN: 
SENR: 
SEND: 
SPT: 
SPA3823(fadB)
SEK: 
SSPA3560(fadB)
SPQ: 
SEI: 
SPC_4090(fadB)
SEC: 
SC3880(fadB)
SEH: 
SHB: 
SENH: 
SEEH: 
SEE: 
SENN: 
SEW: 
SEA: 
SENS: 
SED: 
SeD_A4369(fadB)
SEG: 
SG3469(fadB)
SEL: 
SPUL_3449(fadB)
SEGA: 
SET: 
SEN3777(fadB)
SENJ: 
SEEC: 
SEEB: 
SEEP: 
SENB: 
BN855_40540(SBOV40601)
SENE: 
IA1_19355(fadB)
SES: 
SBG: 
SBG_3514(fadB)
SBZ: 
YPE: 
YPO3766(fadB)
YPK: 
y0464(fadB)
YPA: 
YPA_3436(fadB)
YPN: 
YPN_0198(fadB)
YPM: 
YP_3282(fadB)
YPP: 
YPG: 
YPZ: 
YPZ3_3324(fadB)
YPT: 
YPD: 
YPD4_3315(fadB)
YPX: 
YPD8_3316(fadB)
YPH: 
YPC_0474(fadB)
YPS: 
YPTB0267(fadB)
YPI: 
YPY: 
YPK_3933(fadB)
YPB: 
YPTS_0283(fadB)
YEN: 
YE0268(fadB)
YEP: 
YEY: 
YEL: 
YSI: 
SFL: 
SF3922(fadB)
SFX: 
S3830(fadB)
SFV: 
SFV_3654(fadB)
SFE: 
SFxv_4275(fadB)
SSN: 
SSON_4019(fadB)
SSJ: 
SBC: 
SDY: 
SDY_3899(fadB)
SDZ: 
ECA: 
ECA0208(fadB)
PATR: 
PCT: 
PCC: 
PWA: 
PEC: 
ETA: 
ETA_02460(fadB)
EPY: 
EpC_02330(fadB)
EPR: 
EAM: 
EAMY_0223(fadB)
EAY: 
EAM_0213(fadB)
EBI: 
EbC_02440(fadB)
ERJ: 
PLU: 
plu4402(fadB)
PAY: 
PAU_03873(fadB)
ENT: 
ENC: 
ENO: 
ECLO: 
EEC: 
ENL: 
ESC: 
EAS: 
EAU: 
EAE: 
EAE_08050(fadB)
EAR: 
ENR: 
ESA: 
ESA_03714(fadB)
CSK: 
ES15_3645(fadB)
CSZ: 
CSI: 
CTU: 
CTU_02770(fadB)
KPN: 
KPN_04340(fadB)
KPU: 
KP1_0203(fadB)
KPM: 
KPP: 
KPE: 
KPK_5333(fadB)
KPO: 
KPR: 
KPR_0289(fadB)
KPJ: 
KPI: 
KPA: 
KPS: 
KVA: 
KOX: 
KOX_07835(fadB)
KOE: 
KOY: 
CKO: 
CKO_00188(fadB)
CRO: 
ROD_39091(fadB)
CFD: 
SPE: 
Spro_0261(fadB)
SRR: 
SRL: 
SRY: 
SRS: 
SRA: 
SMAF: 
SMW: 
SLQ: 
SERR: 
SFO: 
PMR: 
PMI3550(fadB)
PMIB: 
DDA: 
DDC: 
DDD: 
DZE: 
XBO: 
XBJ1_0517(fadB)
XNE: 
XNC1_3875(fadB)
PAM: 
PANA_0201(fadB)
PLF: 
PAJ: 
PAJ_3361(fadB)
PAQ: 
PVA: 
Pvag_3442(fadB)
PAO: 
RAH: 
RAQ: 
RAA: 
Q7S_21080(fadB)
PSI: 
S70_07695(fadB)
EBT: 
MMK: 
ROR: 
EBF: 
PSTS: 
VCH: 
VC2758(fadB)
VCE: 
VCJ: 
VCO: 
VCR: 
VCM: 
VCI: 
O3Y_13185(fadB)
VCL: 
VVU: 
VV1_0981(fadB)
VVY: 
VV0029(fadB)
VVM: 
VPA: 
VP0030(fadB)
VPB: 
VPK: 
VPF: 
VPH: 
VHA: 
VCA: 
VAG: 
VSP: 
VS_0041(fadB)
VEX: 
VEJ: 
VFU: 
VNI: 
VAN: 
LAG: 
VFI: 
VF_0025(fadB)
VFM: 
VSA: 
PPR: 
PBPRA0064(fadB)
PAE: 
PA3014(faoA)
PAEV: 
N297_3120(fadB)
PAEI: 
N296_3120(fadB)
PAU: 
PAP: 
PAG: 
PAF: 
PNC: 
PDK: 
PSG: 
PRP: 
PAEP: 
PAER: 
PAEM: 
PAEL: 
PAES: 
PAEU: 
BN889_03366(fadB_1) BN889_03367(fadB_2)
PAEG: 
PAEC: 
M802_3117(fadB)
PAEO: 
M801_2985(fadB)
PPU: 
PP_2136(fadB)
PPF: 
Pput_3606(fadB)
PPG: 
PPW: 
PPT: 
PPB: 
PPI: 
PPX: 
T1E_0604(fadB)
PPUH: 
PPUT: 
PPUN: 
PP4_37140(fadB)
PPUU: 
PST: 
PSB: 
Psyr_3290(fadB)
PSYR: 
PSP: 
PCI: 
PFL: 
PFL_1940(fadB)
PPRC: 
PFO: 
PFS: 
PFLU1553(fadB)
PFE: 
PFC: 
PPZ: 
PEN: 
PSEEN3728(fadB)
PMY: 
Pmen_1580(fadB)
PMK: 
PSA: 
PST_1726(fadB)
PSZ: 
PSR: 
PSC: 
PSJ: 
PSH: 
PBA: 
PBC: 
PFV: 
PDR: 
PRE: 
PSV: 
PSK: 
PMON: 
PMOT: 
PKC: 
PKB_3787(fadB)
PCH: 
AVN: 
AVL: 
AvCA_14440(fadB) AvCA_16390(fadB2)
AVD: 
PAR: 
Psyc_1934(fadB)
PCR: 
PRW: 
PSO: 
ACI: 
ACIAD0335(fadB)
ACD: 
ABM: 
ABSDF3220(fadB)
ABY: 
ABAYE3470(fadB)
ABC: 
ABN: 
AB57_0387(fadB)
ABB: 
ABX: 
ABZ: 
ABR: 
ABD: 
ABH: 
ABAD: 
ABJ: 
ABAB: 
ABAJ: 
ABAZ: 
ACC: 
MCT: 
MCR_0091(fadB)
MCS: 
DR90_1804(fadB)
SON: 
SO_0021(fadB)
SDN: 
Sden_0015(fadB)
SFR: 
Sfri_0013(fadB)
SAZ: 
Sama_0032(fadB)
SBL: 
Sbal_0021(fadB)
SBM: 
SBN: 
SBP: 
SBT: 
SBS: 
SBB: 
SLO: 
Shew_0019(fadB)
SPC: 
SHP: 
SSE: 
Ssed_0023(fadB)
SPL: 
Spea_0018(fadB)
SHE: 
SHM: 
SHN: 
SHW: 
SHL: 
Shal_0016(fadB)
SWD: 
Swoo_0021(fadB)
SWP: 
swp_0035(fadB)
SVO: 
SVI_0052(fadB-1)
ILO: 
IL0011(fadB)
ILI: 
CPS: 
CPS_0393(fadB)
PHA: 
PSHAa0011(fadB)
PAT: 
Patl_0201(fadB)
PSM: 
PSM_A0012(fadB)
SDE: 
MAQ: 
Maqu_1144(fadB)
MHC: 
MARHY2136(fadB)
MAD: 
MBS: 
AMC: 
AMAC: 
AMB: 
AMG: 
AMH: 
AMK: 
AMAA: 
AMAE: 
AMAO: 
AMAD: 
AMAI: 
AMAG: 
ALT: 
AAL: 
GAG: 
GNI: 
GNIT_2932(fadB)
GPS: 
TTU: 
FBL: 
HCH: 
HCH_04756(fadB)
CSA: 
Csal_2393(fadB)
HEL: 
HELO_1758(fadB)
HCS: 
ABO: 
ABO_1652(fadB)
ADI: 
B5T_01517(fadB)
KKO: 
Kkor_0013(fadB)
MMW: 
MME: 
MPC: 
TOL: 
TOR: 
AHA: 
AHA_0139(fadB)
AHY: 
AHD: 
AHR: 
AHP: 
ASA: 
ASA_4250(fadB)
AVR: 
AMED: 
OCE: 
GU3_01845(fadB)
SAGA: 
M5M_01685(fadB) M5M_18535(fadB)
GPB: 
BCT: 
DAR: 
Daro_2350(fadB)
HOH: 
MSL: 
Msil_1395(fadB)
AZL: 
RBA: 
RB1092(faoA)
SACI: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Sato S, Nomura CT, Abe H, Doi Y, Tsuge T
  Title
Poly[(R)-3-hydroxybutyrate] formation in Escherichia coli from glucose through an enoyl-CoA hydratase-mediated pathway.
  Journal
J Biosci Bioeng 103:38-44 (2007)

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