KEGG   ORTHOLOGY: K02159Help
Entry
K02159                      KO                                     

Name
BAX
Definition
apoptosis regulator BAX
Pathway
p53 signaling pathway
Protein processing in endoplasmic reticulum
Apoptosis
Neurotrophin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Amyotrophic lateral sclerosis (ALS)
Huntington's disease
Prion diseases
Tuberculosis
Hepatitis B
HTLV-I infection
Pathways in cancer
Viral carcinogenesis
Colorectal cancer
Disease
H00020  
Colorectal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K02159  BAX; apoptosis regulator BAX
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K02159  BAX; apoptosis regulator BAX
   04115 p53 signaling pathway
    K02159  BAX; apoptosis regulator BAX
 Organismal Systems
  Nervous system
   04722 Neurotrophin signaling pathway
    K02159  BAX; apoptosis regulator BAX
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K02159  BAX; apoptosis regulator BAX
   05203 Viral carcinogenesis
    K02159  BAX; apoptosis regulator BAX
   05210 Colorectal cancer
    K02159  BAX; apoptosis regulator BAX
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    K02159  BAX; apoptosis regulator BAX
   05016 Huntington's disease
    K02159  BAX; apoptosis regulator BAX
   05020 Prion diseases
    K02159  BAX; apoptosis regulator BAX
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K02159  BAX; apoptosis regulator BAX
  Infectious diseases
   05152 Tuberculosis
    K02159  BAX; apoptosis regulator BAX
   05166 HTLV-I infection
    K02159  BAX; apoptosis regulator BAX
   05161 Hepatitis B
    K02159  BAX; apoptosis regulator BAX
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Fission and Fusion factors
    K02159  BAX; apoptosis regulator BAX
BRITE hierarchy
Genes
HSA: 
581(BAX)
PTR: 
747093(BAX)
PPS: 
GGO: 
PON: 
MCC: 
718948(BAX)
MCF: 
MMU: 
12028(Bax)
RNO: 
CGE: 
HGL: 
TUP: 
CFA: 
403523(BAX)
AML: 
FCA: 
493837(BAX)
PTG: 
BTA: 
BOM: 
PHD: 
CHX: 
SSC: 
396633(BAX)
CFR: 
BACU: 
LVE: 
ECB: 
MYD: 
PALE: 
MDO: 
TGU: 
FAB: 
PHI: 
FPG: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
373637(bax)
XTR: 
394793(bax)
DRE: 
100004321 58081(baxa) 767645(im:7148473)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
CIN: 
SPU: 
NVE: 
HMG: 
TAD: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ruiz-Vela A, Opferman JT, Cheng EH, Korsmeyer SJ
  Title
Proapoptotic BAX and BAK control multiple initiator caspases.
  Journal
EMBO Rep 6:379-85 (2005)
Reference
  Authors
Gavathiotis E, Suzuki M, Davis ML, Pitter K, Bird GH, Katz SG, Tu HC, Kim H, Cheng EH, Tjandra N, Walensky LD
  Title
BAX activation is initiated at a novel interaction site.
  Journal
Nature 455:1076-81 (2008)

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