KEGG   ORTHOLOGY: K02324Help
Entry
K02324                      KO                                     
Name
POLE1
Definition
DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
Pathway
Purine metabolism
Pyrimidine metabolism
DNA replication
Base excision repair
Nucleotide excision repair
HTLV-I infection
Module
M00263  
DNA polymerase epsilon complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K02324  POLE1; DNA polymerase epsilon subunit 1
   00240 Pyrimidine metabolism
    K02324  POLE1; DNA polymerase epsilon subunit 1
 Genetic Information Processing
  Replication and repair
   03030 DNA replication
    K02324  POLE1; DNA polymerase epsilon subunit 1
   03410 Base excision repair
    K02324  POLE1; DNA polymerase epsilon subunit 1
   03420 Nucleotide excision repair
    K02324  POLE1; DNA polymerase epsilon subunit 1
 Human Diseases
  Infectious diseases
   05166 HTLV-I infection
    K02324  POLE1; DNA polymerase epsilon subunit 1
KEGG pathway modules [BR:ko00002]
 Structural complex
  Genetic information processing
   DNA polymerase
    M00263  DNA polymerase epsilon complex [BR:ko03032 ko03400]
     K02324  POLE1; DNA polymerase epsilon subunit 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K02324  POLE1; DNA polymerase epsilon subunit 1
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    K02324  POLE1; DNA polymerase epsilon subunit 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      K02324  POLE1; DNA polymerase epsilon subunit 1
BRITE hierarchy
Other DBs
Genes
HSA: 
5426(POLE)
PTR: 
452384(POLE) 467165(POLE)
PPS: 
100994929(POLE)
GGO: 
101124678(POLE)
PON: 
100457382(POLE)
MCC: 
698023(POLE)
MMU: 
18973(Pole)
RNO: 
304573(Pole)
CFA: 
486223(POLE)
AML: 
100468260(POLE)
FCA: 
101096921(POLE)
BTA: 
785457(POLE)
SSC: 
100620959(POLE)
ECB: 
100061669
MDO: 
100027569(POLE)
SHR: 
100930494(POLE)
GGA: 
416997(POLE)
MGP: 
100546821(POLE)
TGU: 
100227333(POLE)
ACS: 
100553994(pole)
XTR: 
100498309(pole)
DRE: 
553405(pole)
TRU: 
101077972
OLA: 
101171586
BFO: 
BRAFLDRAFT_84229 BRAFLDRAFT_84230
CIN: 
100175840
SPU: 
589064
DME: 
Dmel_CG6768(DNApol-epsilon)
DPO: 
Dpse_GA19850
DAN: 
Dana_GF16992
DER: 
Dere_GG11199
DPE: 
Dper_GL13784
DSE: 
Dsec_GM26499
DSI: 
Dsim_GD21012
DWI: 
Dwil_GK10841
DYA: 
Dyak_GE10366
DGR: 
Dgri_GH20086
DMO: 
Dmoj_GI24369
DVI: 
Dvir_GJ24376
AGA: 
AgaP_AGAP004615
AAG: 
AaeL_AAEL002800
CQU: 
CpipJ_CPIJ008666
AME: 
409673(DNApol-epsilon)
NVI: 
100114949(NV16063)
TCA: 
657660
API: 
100164975
PHU: 
Phum_PHUM420020
CEL: 
CELE_F33H2.5(F33H2.5)
CBR: 
CBG19758
BMY: 
Bm1_41890
TSP: 
Tsp_07270
SMM: 
Smp_146170
NVE: 
NEMVE_v1g119951
HMG: 
100207477
TAD: 
TRIADDRAFT_30078
AQU: 
100640956
ATH: 
AT1G08260(TIL1) AT2G27120(TIL2)
ALY: 
ARALYDRAFT_888057 ARALYDRAFT_901556
GMX: 
100778115 100812003
MTR: 
MTR_4g054980
CSV: 
101208568
RCU: 
RCOM_0792580
POP: 
POPTR_594813
VVI: 
100241432(POLE)
OSA: 
4329458
DOSA: 
Os02t0511900-00(Os02g0511900) Os02t0511901-00(Os02g0511901)
BDI: 
100829409(POLE)
SBI: 
SORBI_04g020730(SORBIDRAFT_04g020730)
ZMA: 
100279392
SMO: 
SELMODRAFT_442263 SELMODRAFT_445541
PPP: 
PHYPADRAFT_136896
CRE: 
CHLREDRAFT_9481(POLE1)
VCN: 
VOLCADRAFT_116136
OLU: 
OSTLU_150
OTA: 
Ot11g02010
CME: 
CMQ098C
SCE: 
YNL262W(POL2)
AGO: 
AGOS_AFR657C
ERC: 
Ecym_1099
KLA: 
KLLA0C02585g
LTH: 
KLTH0F02640g
PPA: 
PAS_chr1-3_0083
VPO: 
Kpol_2000p54
ZRO: 
ZYRO0F16412g
CGR: 
CAGL0J08030g
NCS: 
NCAS_0A00660(NCAS0A00660)
NDI: 
NDAI_0F04140(NDAI0F04140)
TPF: 
TPHA_0B04380(TPHA0B04380)
TBL: 
TBLA_0A05580(TBLA0A05580)
TDL: 
TDEL_0C06080(TDEL0C06080)
KAF: 
KAFR_0D03890(KAFR0D03890)
DHA: 
DEHA2E22000g
PIC: 
PICST_66970(POL2)
PGU: 
PGUG_01613
LEL: 
LELG_03145 LELG_03147
CAL: 
CaO19.2365(POL2) CaO19.9901(POL2)
CTP: 
CTRG_00708
CDU: 
CD36_32530
COT: 
CORT_0D05520
YLI: 
YALI0E26367g
CLU: 
CLUG_00743 CLUG_00744
NCR: 
NCU04548
SMP: 
SMAC_06069
PAN: 
PODANSg1900
TTT: 
THITE_2117750
MTM: 
MYCTH_2139989
MGR: 
MGG_03850
FGR: 
FG06065.1
NHE: 
NECHADRAFT_20015
VAL: 
VDBG_03087
SSL: 
SS1G_11933
BFU: 
BC1G_10334
ANI: 
AN3067.2
NFI: 
NFIA_067730
AFM: 
AFUA_3G09560
AOR: 
AOR_1_2240174(AO090005001292)
AFV: 
AFLA_085310
ACT: 
ACLA_037330
PCS: 
Pc12g15980
CIM: 
CIMG_01894
CPW: 
CPC735_046170
PBL: 
PAAG_07398
URE: 
UREG_06843
ABE: 
ARB_01174
TVE: 
TRV_03251
AJE: 
HCAG_05419
PNO: 
SNOG_11951
PTE: 
PTT_19357
ZTR: 
MYCGRDRAFT_76789
TML: 
GSTUM_00007495001
SPO: 
SPBC25H2.13c(cdc20)
CNE: 
CNK01430
CNB: 
CNBK2100
CGI: 
CGB_K2570C
LBC: 
LACBIDRAFT_312780
MPR: 
MPER_01343 MPER_05209 MPER_10345
CCI: 
CC1G_09909
SCM: 
SCHCODRAFT_74334
UMA: 
UM01008.1
MGL: 
MGL_0515
PGR: 
PGTG_17326
ECU: 
ECU10_1210
EIN: 
Eint_101160
EHE: 
EHEL_101230
NCE: 
NCER_100184
MBR: 
MONBRDRAFT_15015
NGR: 
NAEGRDRAFT_59151
DDI: 
DDB_G0283189
DPP: 
DICPUDRAFT_94903
PFA: 
PFF1470c
PFD: 
PFDG_02178
PFH: 
PFHG_04267
PYO: 
PY05353 PY06086
PCB: 
PC000380.01.0 PC300986.00.0
PBE: 
PB000449.01.0
PKN: 
PKH_111860
PVX: 
PVX_114615
PCY: 
PCYB_112770
TAN: 
TA09840
TPV: 
TP04_0813 TP04_0814
BBO: 
BBOV_III009080(17.m07793)
CPV: 
cgd8_1240
CHO: 
Chro.80147
TGO: 
TGME49_119860
TET: 
TTHERM_00112520
PTM: 
GSPATT00033819001
TBR: 
Tb09.211.1820
TCR: 
506147.180 510733.60
LIF: 
LINJ_35_4430
LDO: 
LDBPK_354430
LMI: 
LMXM_34_4360
LBZ: 
LBRM_34_4340
GLA: 
GL50803_23064
TVA: 
TVAG_197030
PTI: 
PHATRDRAFT_52678
TPS: 
THAPSDRAFT_268553
PIF: 
PITG_15505
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8087839
  Authors
Stillman B.
  Title
Smart machines at the DNA replication fork.
  Journal
Cell 78:725-8 (1994)
DBGET integrated database retrieval system