KEGG   ORTHOLOGY: K02324Help
Entry
K02324                      KO                                     

Name
POLE
Definition
DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
Pathway
ko00230  Purine metabolism
ko00240  Pyrimidine metabolism
ko01100  Metabolic pathways
ko03030  DNA replication
ko03410  Base excision repair
ko03420  Nucleotide excision repair
ko05166  HTLV-I infection
Module
M00263  DNA polymerase epsilon complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K02324  POLE; DNA polymerase epsilon subunit 1
   00240 Pyrimidine metabolism
    K02324  POLE; DNA polymerase epsilon subunit 1
 Genetic Information Processing
  Replication and repair
   03030 DNA replication
    K02324  POLE; DNA polymerase epsilon subunit 1
   03410 Base excision repair
    K02324  POLE; DNA polymerase epsilon subunit 1
   03420 Nucleotide excision repair
    K02324  POLE; DNA polymerase epsilon subunit 1
 Human Diseases
  Infectious diseases
   05166 HTLV-I infection
    K02324  POLE; DNA polymerase epsilon subunit 1
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   DNA polymerase
    M00263  DNA polymerase epsilon complex
     K02324  POLE; DNA polymerase epsilon subunit 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K02324  POLE; DNA polymerase epsilon subunit 1
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    K02324  POLE; DNA polymerase epsilon subunit 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      K02324  POLE; DNA polymerase epsilon subunit 1
BRITE hierarchy
Other DBs
RN: R00375 R00376 R00377 R00378
COG: COG0417
GO: 0003887
Genes
HSA: 5426(POLE)
PTR: 467165(POLE)
PPS: 100994929(POLE)
GGO: 101124678(POLE)
PON: 100457382(POLE)
NLE: 100586999(POLE)
MCC: 698023(POLE)
MCF: 102128564(POLE) 102136347
CSAB: 103239455(POLE)
RRO: 104674305(POLE)
RBB: 108544513(POLE)
CJC: 100409761(POLE)
SBQ: 101027910(POLE)
MMU: 18973(Pole)
RNO: 304573(Pole)
CGE: 100774671(Pole)
NGI: 103750601(Pole)
HGL: 101720520(Pole)
CCAN: 109686269(Pole)
OCU: 100338950(POLE)
TUP: 102498444(POLE)
CFA: 486223(POLE)
AML: 100468260(POLE)
UMR: 103678890(POLE)
ORO: 101370582(POLE)
FCA: 101096921(POLE)
PTG: 102961044(POLE)
AJU: 106985893(POLE)
BTA: 785457(POLE)
BOM: 102275686(POLE)
BIU: 109571514(POLE)
PHD: 102329727(POLE)
CHX: 102174589(POLE)
OAS: 101116176(POLE)
SSC: 100620959(POLE)
CFR: 102506685(POLE)
CDK: 105104087(POLE)
BACU: 103019668(POLE)
LVE: 103075841(POLE)
OOR: 101280243(POLE)
ECB: 100061669(POLE)
EPZ: 103561638(POLE)
EAI: 106843873(POLE)
MYB: 102261008(POLE)
MYD: 102754827(POLE)
HAI: 109376144(POLE)
RSS: 109456462(POLE)
PALE: 102892506(POLE)
LAV: 100655118(POLE)
TMU: 101346520
MDO: 100027569(POLE)
SHR: 100930494(POLE)
OAA: 100080168(POLE)
GGA: 416997(POLE)
MGP: 100546821(POLE)
CJO: 107321357(POLE)
APLA: 101790280(POLE)
ACYG: 106047461(POLE)
TGU: 100227333(POLE)
GFR: 102044866(POLE)
FAB: 101811602(POLE)
PHI: 102114706(POLE)
PMAJ: 107211805(POLE)
CCW: 104695018(POLE)
FPG: 101917713(POLE)
FCH: 102049824(POLE)
CLV: 102087575(POLE)
EGZ: 104129954(POLE)
AAM: 106487395(POLE)
ASN: 102383079(POLE)
AMJ: 102563567(POLE) 109283538
PSS: 102447256(POLE)
CMY: 102936542(POLE)
CPIC: 101953633(POLE)
ACS: 100553994(pole)
PBI: 103049755(POLE)
GJA: 107122105(POLE)
XLA: 394427(pole.L)
XTR: 100498309(pole)
NPR: 108786269(POLE)
DRE: 553405(pole)
IPU: 108255721(pole)
AMEX: 103040955(pole)
TRU: 101077972(pole)
LCO: 104921249(pole)
NCC: 104945035(pole)
MZE: 101477333(pole)
OLA: 101171586(pole)
XMA: 102229683(pole)
PRET: 103470347(pole)
NFU: 107393957(pole)
CSEM: 103397307(pole)
LCF: 108878119(pole)
HCQ: 109511643(pole)
BPEC: 110156718(pole)
SASA: 106580112(pole)
ELS: 105014433(pole)
SFM: 108932609(pole)
LCM: 102354933(POLE)
CMK: 103184063(pole)
CIN: 100175840
SPU: 589064
APLC: 110983491
SKO: 100367259
DME: Dmel_CG6768(DNApol-epsilon255)
DSI: Dsimw501_GD21012(Dsim_GD21012)
MDE: 101898658
AAG: 5576108
AME: 409673(DNApol-epsilon)
BIM: 100741328
BTER: 100644263
SOC: 105199658
AEC: 105151595
ACEP: 105617488
PBAR: 105431386
HST: 105192209
CFO: 105252186
LHU: 105677922
PGC: 109851666
NVI: 100114949
TCA: 657660
DPA: 109536243
NVL: 108569051
BMOR: 101742003
PRAP: 110994309
API: 100164975
DNX: 107166146
ZNE: 110831436
FCD: 110842609
CEL: CELE_F33H2.5(pole-1)
CBR: CBG19758
BMY: Bm1_41890
TSP: Tsp_07270
CRG: 105328709
MYI: 110462861
SHX: MS3_06279
EPA: 110234119
HMG: 100207477
AQU: 100640956
ATH: AT1G08260(TIL1) AT2G27120(TIL2)
CRB: 17900286
BRP: 103871570
BOE: 106295016
THJ: 104826411
CPAP: 110817276
CIT: 102608212
TCC: 18590361
DZI: 111285079
VRA: 106756208
VAR: 108340273
CCAJ: 109798448
CAM: 101514286
ADU: 107476420
AIP: 107629315
LJA: Lj3g3v2995970.1(Lj3g3v2995970.1) Lj3g3v2995970.2(Lj3g3v2995970.2)
FVE: 101291492
PPER: 18772839
PMUM: 103327021
ZJU: 107410533
CSV: 101208568
CMO: 103497954
CMAX: 111491125
CMOS: 111459170
CPEP: 111795204
RCU: 8277599
JCU: 105637094
HBR: 110654153
POP: 18097958
JRE: 109008755
VVI: 100241432(POLE)
SLY: 101253967
SPEN: 107004841
SOT: 102599922
NTO: 104119602
INI: 109158540
SIND: 105171162
OEU: 111383059
HAN: 110940900
DCR: 108215229
BVG: 104900347
SOE: 110791677
NNU: 104586917
OSA: 4329458
DOSA: Os02t0511900-00(Os02g0511900) Os02t0511901-00(Os02g0511901)
OBR: 102722465
BDI: 100829409
ATS: 109778776(LOC109778776)
SBI: 8056089
SITA: 101780569
PDA: 103719838
EGU: 105035197
MUS: 103998275
DCT: 110113617
ATR: 18441362
PPP: 112290298
CRE: CHLREDRAFT_9481(POLE1)
OLU: OSTLU_150
APRO: F751_0448
SCE: YNL262W(POL2)
ERC: Ecym_1099
KMX: KLMA_10117(POL2)
NCS: NCAS_0A00660(NCAS0A00660)
NDI: NDAI_0F04140(NDAI0F04140)
TPF: TPHA_0B04380(TPHA0B04380)
TBL: TBLA_0A05580(TBLA0A05580)
TDL: TDEL_0C06080(TDEL0C06080)
KAF: KAFR_0D03890(KAFR0D03890)
PIC: PICST_66970(POL2)
CAL: CAALFM_CR07000CA(POL2)
SLB: AWJ20_3963(POL2)
NCR: NCU04548
NTE: NEUTE1DRAFT123761(NEUTE1DRAFT_123761)
MGR: MGG_03850
MAW: MAC_01906
MAJ: MAA_04664
CMT: CCM_01023
MBE: MBM_04038
ANI: AN3067.2
ANG: ANI_1_434144(An16g03060)
ABE: ARB_01174
TVE: TRV_03251
PTE: PTT_19357
SPO: SPBC25H2.13c(cdc20)
CNE: CNK01430
CNB: CNBK2100
ABP: AGABI1DRAFT61718(AGABI1DRAFT_61718)
ABV: AGABI2DRAFT188103(AGABI2DRAFT_188103)
MGL: MGL_0515
DFA: DFA_07560
PYO: PY17X_1130600(PY05353)
PCB: PCHAS_112860(PC000380.01.0)
TAN: TA09840
BBO: BBOV_III009080(17.m07793)
CPV: cgd8_1240
SMIN: v1.2.001887.t1(symbB.v1.2.001887.t1) v1.2.001887.t2(symbB.v1.2.001887.t2) v1.2.001887.t3(symbB.v1.2.001887.t3)
SPAR: SPRG_04353
EHX: EMIHUDRAFT_106805(POLE1)
GTT: GUITHDRAFT_97375(POLE1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Shimizu K, Hashimoto K, Kirchner JM, Nakai W, Nishikawa H, Resnick MA, Sugino A
  Title
Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae.
  Journal
J Biol Chem 277:37422-9 (2002)
DOI:10.1074/jbc.M204476200
  Sequence
[sce:YNL262W]

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