KEGG   ORTHOLOGY: K02330Help
Entry
K02330                      KO                                     

Name
POLB
Definition
DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
Pathway
Base excision repair
HTLV-I infection
Viral carcinogenesis
Module
M00296  
BER complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03410 Base excision repair
    K02330  POLB; DNA polymerase beta
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K02330  POLB; DNA polymerase beta
  Infectious diseases
   05166 HTLV-I infection
    K02330  POLB; DNA polymerase beta
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Repair system
    M00296  BER complex
     K02330  POLB; DNA polymerase beta
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K02330  POLB; DNA polymerase beta
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.-  
     K02330  POLB; DNA polymerase beta
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Short Patch-BER factors
     K02330  POLB; DNA polymerase beta
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    X-family DNA polymerases
     K02330  POLB; DNA polymerase beta
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5423(POLB)
PTR: 
737210(POLB)
PPS: 
100990190(POLB)
GGO: 
101144130(POLB)
PON: 
100441812(POLB)
NLE: 
100588738(POLB)
MCC: 
704801(POLB)
MCF: 
102115303(POLB)
CJC: 
100393825(POLB)
MMU: 
18970(Polb)
RNO: 
29240(Polb)
CGE: 
100774965(Polb)
NGI: 
103726620(Polb)
HGL: 
101710722(Polb)
OCU: 
100348691(POLB)
TUP: 
102502435(POLB)
CFA: 
494001(POLB)
AML: 
UMR: 
103677058(POLB)
FCA: 
101099797(POLB)
PTG: 
102963455(POLB)
BTA: 
614688(POLB)
BOM: 
102281166(POLB)
PHD: 
102337510(POLB)
CHX: 
102177689(POLB)
OAS: 
101122327(POLB)
SSC: 
100526021(POLB)
CFR: 
102508539(POLB)
BACU: 
103013074(POLB)
LVE: 
103088370(POLB)
ECB: 
MYB: 
102254615(POLB)
MYD: 
102773539(POLB)
PALE: 
102893018(POLB)
MDO: 
100030148(POLB)
SHR: 
100929187(POLB)
OAA: 
100078894(POLB)
GGA: 
426794(POLB)
MGP: 
APLA: 
101792343(POLB)
TGU: 
FAB: 
101818872(POLB)
PHI: 
102100382(POLB)
FPG: 
101922234(POLB)
FCH: 
102058720(POLB)
CLV: 
102087419(POLB)
ASN: 
AMJ: 
PSS: 
102449407(POLB)
CMY: 
102931250(POLB)
ACS: 
100552750(polb)
PBI: 
XLA: 
397973(polb)
XTR: 
448741(polb)
DRE: 
554204(polb)
TRU: 
MZE: 
OLA: 
XMA: 
102224288(polb)
LCM: 
102356930(POLB)
CMK: 
103191220(polb)
BFO: 
CIN: 
SPU: 
NVI: 
TCA: 
API: 
PHU: 
ISC: 
HRO: 
NVE: 
TAD: 
AQU: 
OLU: 
CNB: 
TMS: 
SHS: 
PSQ: 
FME: 
GTR: 
LBC: 
MRR: 
CCI: 
CPUT: 
UMA: 
MBR: 
DDI: 
DPP: 
DFA: 
DFA_04253(gxcFF)
ACAN: 
TBR: 
Tb927.5.2780(Tb05.26K5.520) Tb927.5.2790(Tb05.26K5.490)
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Moon AF, Garcia-Diaz M, Batra VK, Beard WA, Bebenek K, Kunkel TA, Wilson SH, Pedersen LC
  Title
The X family portrait: structural insights into biological functions of X family polymerases.
  Journal
DNA Repair (Amst) 6:1709-25 (2007)
Reference
  Authors
DeMott MS, Beyret E, Wong D, Bales BC, Hwang JT, Greenberg MM, Demple B
  Title
Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone.
  Journal
J Biol Chem 277:7637-40 (2002)
  Sequence
[hsa:5423]

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