KEGG   ORTHOLOGY: K02353Help
Entry
K02353                      KO                                     

Name
DVL
Definition
segment polarity protein dishevelled
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04330  Notch signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing's syndrome
ko05165  Human papillomavirus infection
ko05166  HTLV-I infection
ko05200  Pathways in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Module
M00677  Wnt signaling
Disease
H00485  Robinow syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K02353  DVL; segment polarity protein dishevelled
   04330 Notch signaling pathway
    K02353  DVL; segment polarity protein dishevelled
   04390 Hippo signaling pathway
    K02353  DVL; segment polarity protein dishevelled
   04150 mTOR signaling pathway
    K02353  DVL; segment polarity protein dishevelled
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K02353  DVL; segment polarity protein dishevelled
 Organismal Systems
  Endocrine system
   04916 Melanogenesis
    K02353  DVL; segment polarity protein dishevelled
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K02353  DVL; segment polarity protein dishevelled
   05225 Hepatocellular carcinoma
    K02353  DVL; segment polarity protein dishevelled
   05226 Gastric cancer
    K02353  DVL; segment polarity protein dishevelled
   05217 Basal cell carcinoma
    K02353  DVL; segment polarity protein dishevelled
   05224 Breast cancer
    K02353  DVL; segment polarity protein dishevelled
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    K02353  DVL; segment polarity protein dishevelled
  Infectious diseases
   05166 HTLV-I infection
    K02353  DVL; segment polarity protein dishevelled
   05165 Human papillomavirus infection
    K02353  DVL; segment polarity protein dishevelled
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00677  Wnt signaling
     K02353  DVL; segment polarity protein dishevelled
BRITE hierarchy
Genes
HSA: 1855(DVL1) 1856(DVL2) 1857(DVL3)
PTR: 455236(DVL2) 457191(DVL1) 460882(DVL3)
PPS: 100977837(DVL3) 100986952(DVL2) 100991559(DVL1)
GGO: 101141318(DVL1) 101145045(DVL3) 101146042(DVL2)
PON: 100448038(DVL3) 100454011(DVL2) 100454488(DVL1)
NLE: 100583216(DVL3) 100585595(DVL2) 100593186(DVL1)
MCC: 100423838(DVL3) 705864(DVL1) 714381(DVL2)
MCF: 102130032(DVL3) 102138928(DVL1) 102143975(DVL2)
CSAB: 103221145(DVL3) 103225806(DVL1) 103242279(DVL2)
RRO: 104655760(DVL1) 104664635(DVL3) 104673334(DVL2) 104679742
RBB: 108514297(DVL2) 108522287 108524838(DVL3) 108544197(DVL1)
CJC: 100388569(DVL1) 100390081(DVL3) 100398229(DVL2)
SBQ: 101028835(DVL2) 101035529(DVL1) 101044711(DVL3)
MMU: 13542(Dvl1) 13543(Dvl2) 13544(Dvl3)
RNO: 303251(Dvl2) 303811(Dvl3) 83721(Dvl1)
CGE: 100762587(Dvl2) 100770288(Dvl1) 100773535(Dvl3)
NGI: 103732646(Dvl3) 103749746(Dvl1) 103752158(Dvl2)
HGL: 101710629(Dvl2) 101715426(Dvl1) 101716996(Dvl3)
CCAN: 109674455(Dvl2) 109681149(Dvl1) 109694105(Dvl3)
OCU: 100339336(DVL2) 100358367(DVL3)
TUP: 102468994(DVL1) 102472352(DVL3) 102485749(DVL2)
CFA: 100855811(DVL1) 478650(DVL3) 489464(DVL2)
AML: 100466067(DVL3) 100471972(DVL1) 100480005(DVL2)
UMR: 103660462(DVL2) 103676184(DVL3) 103682075
ORO: 101362760(DVL1) 101375453(DVL2) 101380123(DVL3)
FCA: 101084782(DVL1) 101094385(DVL2) 101095675(DVL3)
PTG: 102954084(DVL3) 102957003(DVL1) 102967723(DVL2)
AJU: 106972415(DVL2) 106983787(DVL3) 106988759(DVL1)
BTA: 523325(DVL1) 539203(DVL3) 614312(DVL2)
BOM: 102273776(DVL2) 102280462(DVL3) 102287954(DVL1)
BIU: 109562775(DVL3) 109570328(DVL1) 109573933(DVL2)
PHD: 102319823(DVL1) 102331639(DVL3) 102338674(DVL2)
CHX: 102182444(DVL3) 102188083(DVL2) 102189698(DVL1)
OAS: 101104259(DVL1) 101107926(DVL3) 101117599(DVL2)
SSC: 100525170(DVL1) 100621038(DVL3) 100625452(DVL2)
CFR: 102504125(DVL1) 102508928(DVL3) 102516993(DVL2)
CDK: 105085889(DVL3) 105103047(DVL2) 105105575(DVL1)
BACU: 103001138(DVL2) 103006135(DVL1) 103009589(DVL3)
LVE: 103078766(DVL2) 103082466(DVL3) 103086975(DVL1)
OOR: 101270557(DVL3) 101274659(DVL2) 101278332(DVL1)
ECB: 100061612(DVL2) 100147200(DVL1) 100147654(DVL3)
EPZ: 103542807(DVL1) 103554749(DVL3) 103557742(DVL2)
EAI: 106834527(DVL3) 106844176(DVL2) 106845228(DVL1)
MYB: 102242768(DVL1) 102247666(DVL3) 102263975(DVL2)
MYD: 102751460(DVL3) 102770215(DVL1) 102771718(DVL2)
HAI: 109371312(DVL3) 109391189(DVL1) 109394615(DVL2)
RSS: 109434809(DVL1) 109449521(DVL3) 109454443(DVL2)
PALE: 102880039(DVL2) 102881158(DVL1) 102895469(DVL3)
LAV: 100657649(DVL1) 100657749(DVL2) 100673586(DVL3)
MDO: 100010047(DVL1) 100022768(DVL3) 100617787(DVL2)
SHR: 100931932(DVL2) 100932119(DVL3) 100932600(DVL1)
OAA: 100091980
GGA: 419416(MIR6808) 424949(DVL3)
MGP: 100542700(DVL3) 100542715(DVL1)
CJO: 107318246(DVL3) 107323265(DVL1)
APLA: 101795365(DVL1) 101803917(DVL3)
ACYG: 106044602(DVL1) 106049394(DVL3)
TGU: 100220188(DVL3) 100231182(DVL1)
GFR: 102039062(DVL3) 102042753(DVL1)
FAB: 101814246(DVL1) 101819961(DVL3)
PHI: 102100381(DVL1) 102106626(DVL3)
PMAJ: 107208764(DVL3) 107213612(DVL1)
CCW: 104687975(DVL3) 104693398(DVL1)
FPG: 101911922(DVL3) 101912223(DVL1)
FCH: 102050159(DVL1) 102058771(DVL3)
CLV: 102083825(DVL1) 102090902(DVL3)
EGZ: 104122225(DVL3) 104133401(DVL1)
AAM: 106483786 106483810(DVL3) 106495571(DVL1)
ASN: 102368492(DVL3) 102369873(DVL2) 102374968(DVL1)
AMJ: 102570134(DVL2) 102577127(DVL1) 106736875(DVL3)
PSS: 102444255(DVL2) 102448187(DVL1) 102456265(DVL3)
CMY: 102935034(DVL3) 102940481(DVL1)
CPIC: 101944412(DVL3) 101944935(DVL2) 101945376(DVL1)
PVT: 110073291(DVL1) 110082311(DVL2) 110090056(DVL3)
GJA: 107107424(DVL3) 107118069(DVL2) 107118298(DVL1)
XLA: 100381153(dvl1.L) 108697641 108703580 108718034 399301(dvl2.L) 444527(dvl3.L)
XTR: 100144639(dvl1) 100144702(dvl3) 780117(dvl2)
NPR: 108784332(DVL1) 108803700(DVL2) 108804026 108804693(DVL3)
DRE: 100149082(dvl3) 323630(dvl2) 560032(dvl1b) 569863(dvl1a) 80972(dvl3a)
IPU: 108264349(dvl3) 108268006 108268205(dvl2) 108276110(dvl1)
TRU: 101061269(dvl2) 101061354 101065936(dvl3) 101074176(dvl1)
LCO: 104924672(dvl1) 104933929(dvl3) 104934174 104937819(dvl2)
OLA: 101157324(dvl3) 101163770(dvl2) 101165393(dvl1)
NFU: 107372429(dvl2) 107379914(dvl3) 107384150 107390467(dvl1)
CSEM: 103382638(dvl3) 103385359(dvl1) 103386914(dvl2) 103395894
LCF: 108882158(dvl1) 108883643(dvl3) 108897075(dvl2) 108902917
BPEC: 110157674(dvl2) 110164535(dvl1) 110173568(dvl3)
LCM: 102349092 102356490(DVL2) 102358902(DVL1) 102364030(DVL3)
CMK: 103181449(dvl1) 103187995(dvl3)
CIN: 445782(dsh)
SPU: 584189
APLC: 110978958
SKO: 100374125(dvl)
DME: Dmel_CG18361(dsh)
DSI: Dsimw501_GD29351(Dsim_GD29351)
MDE: 101897435
AAG: 5570297
AME: 409050(dsh)
BIM: 100747477
BTER: 100647590
SOC: 105197726
AEC: 105148755
ACEP: 105624974
PBAR: 105422062
HST: 105191205
CFO: 105257731
LHU: 105679300
PGC: 109852813
NVI: 100124213
TCA: 655946
DPA: 109539978
NVL: 108566391
BMOR: 101740539
PMAC: 106720864
PRAP: 110996112
API: 100166217
DNX: 107165836
ZNE: 110827516
FCD: 110846397
DPX: DAPPUDRAFT_346802(DSH1)
CEL: CELE_C27A2.6(dsh-2) CELE_C34F11.9(dsh-1)
CBR: CBG02318(Cbr-dsh-2) CBG02352(Cbr-dsh-1)
BMY: Bm1_23120
TSP: Tsp_08621
CRG: 105324971
MYI: 110455289
OBI: 106876540
ADF: 107338504
HMG: 100205784
AQU: 100616091(Dvl)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kikuchi K, Niikura Y, Kitagawa K, Kikuchi A
  Title
Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1.
  Journal
EMBO J 29:3470-83 (2010)
DOI:10.1038/emboj.2010.221
Reference
PMID:9192851
  Authors
Semenov MV, Snyder M
  Title
Human dishevelled genes constitute a DHR-containing multigene family.
  Journal
Genomics 42:302-10 (1997)
DOI:10.1006/geno.1997.4713
  Sequence
[hsa:1855 1856 1857]

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