KEGG   ORTHOLOGY: K02373Help
Entry
K02373                      KO                                     

Name
FADD
Definition
FAS-associated death domain protein
Pathway
Platinum drug resistance
Apoptosis
Apoptosis - multiple species
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Toll and Imd signaling pathway
TNF signaling pathway
Alzheimer's disease
Chagas disease (American trypanosomiasis)
Tuberculosis
Hepatitis B
Herpes simplex infection
Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04668 TNF signaling pathway
    K02373  FADD; FAS-associated death domain protein
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K02373  FADD; FAS-associated death domain protein
   04215 Apoptosis - multiple species
    K02373  FADD; FAS-associated death domain protein
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K02373  FADD; FAS-associated death domain protein
   04624 Toll and Imd signaling pathway
    K02373  FADD; FAS-associated death domain protein
   04621 NOD-like receptor signaling pathway
    K02373  FADD; FAS-associated death domain protein
   04622 RIG-I-like receptor signaling pathway
    K02373  FADD; FAS-associated death domain protein
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K02373  FADD; FAS-associated death domain protein
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K02373  FADD; FAS-associated death domain protein
  Infectious diseases
   05152 Tuberculosis
    K02373  FADD; FAS-associated death domain protein
   05161 Hepatitis B
    K02373  FADD; FAS-associated death domain protein
   05168 Herpes simplex infection
    K02373  FADD; FAS-associated death domain protein
   05142 Chagas disease (American trypanosomiasis)
    K02373  FADD; FAS-associated death domain protein
  Drug resistance
   01524 Platinum drug resistance
    K02373  FADD; FAS-associated death domain protein
BRITE hierarchy
Genes
HSA: 
8772(FADD)
PTR: 
451389(FADD)
PPS: 
100968673(FADD)
GGO: 
101134274(FADD)
PON: 
100439256(FADD)
NLE: 
100607557(FADD)
MCC: 
708606(FADD)
MCF: 
101866285(FADD)
CSAB: 
103245758(FADD)
RRO: 
104677132(FADD)
CJC: 
100410616(FADD)
SBQ: 
101046905(FADD)
MMU: 
14082(Fadd)
RNO: 
266610(Fadd)
CGE: 
100774599(Fadd)
NGI: 
103751502(Fadd)
HGL: 
101709972(Fadd)
OCU: 
103346753(FADD)
TUP: 
102489799(FADD)
CFA: 
611694(FADD)
AML: 
100468003(FADD)
UMR: 
103671072(FADD)
FCA: 
101087871(FADD)
PTG: 
102965744(FADD)
BTA: 
493720(FADD)
BOM: 
102271962(FADD)
PHD: 
102330217(FADD)
CHX: 
102170760(FADD)
OAS: 
101116783(FADD)
SSC: 
100737955(FADD) 595129(FADD)
CFR: 
102519266(FADD)
BACU: 
103014148(FADD)
LVE: 
103080339(FADD)
ECB: 
100061802(FADD)
MYD: 
102756704(FADD)
PALE: 
102892511(FADD)
LAV: 
100662633(FADD)
MDO: 
100031941(FADD)
SHR: 
100925732(FADD)
OAA: 
100075638(FADD)
GGA: 
423146(FADD)
MGP: 
100540536(FADD)
CJO: 
107314471(FADD)
APLA: 
101801863(FADD)
TGU: 
100229649(FADD)
GFR: 
102042362(FADD)
FAB: 
101806236(FADD)
PHI: 
102102219(FADD)
CCW: 
104697634(FADD)
FPG: 
101918701(FADD)
FCH: 
102055286(FADD)
CLV: 
102085703(FADD)
AAM: 
106498371(FADD)
ASN: 
102377608(FADD)
AMJ: 
102572187(FADD)
PSS: 
102448271(FADD)
CMY: 
102930159(FADD)
ACS: 
103279978(fadd)
PBI: 
103054174(FADD)
GJA: 
107118889(FADD)
XLA: 
496403(fadd.S)
XTR: 
100379789(fadd)
DRE: 
562317(fadd)
TRU: 
101067067(fadd)
MZE: 
101483780(fadd)
OLA: 
100049399(fadd)
XMA: 
102230597(fadd)
SASA: 
106561969(FADD) 106587129(FADD)
LCM: 
102357786(FADD)
CMK: 
103175018(fadd)
BFO: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD20917(Dsim_GD20917)
DWI: 
DYA: 
Dyak_GE10264(dyak_GLEANR_10204)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
AME: 
BIM: 
BTER: 
SOC: 
AEC: 
HST: 
CFO: 
TCA: 
103312947(Fadd)
BMOR: 
DPL: 
PXY: 
LGI: 
CRG: 
OBI: 
HMG: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7538907
  Authors
Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM
  Title
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
  Journal
Cell 81:505-12 (1995)
  Sequence
[hsa:8772]
Reference
  Authors
Bolze A, Byun M, McDonald D, Morgan NV, Abhyankar A, Premkumar L, Puel A, Bacon CM, Rieux-Laucat F, Pang K, Britland A, Abel L, Cant A, Maher ER, Riedl SJ, Hambleton S, Casanova JL
  Title
Whole-exome-sequencing-based discovery of human FADD deficiency.
  Journal
Am J Hum Genet 87:873-81 (2010)
  Sequence
[hsa:8772]

DBGET integrated database retrieval system