KEGG   ORTHOLOGY: K02539Help
Entry
K02539                      KO                                     

Name
MCL1
Definition
myeloid leukemia cell differntiation protein MCL-1
Pathway
ko04151  PI3K-Akt signaling pathway
ko04210  Apoptosis
ko04630  Jak-STAT signaling pathway
ko05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
   04151 PI3K-Akt signaling pathway
    K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
BRITE hierarchy
Genes
HSA: 4170(MCL1)
PTR: 457274(MCL1)
PPS: 100979595(MCL1)
GGO: 101137633(MCL1)
PON: 100436188(MCL1)
NLE: 100604947(MCL1)
MCC: 707539(MCL1)
MCF: 101925224(MCL1)
CSAB: 103247197(MCL1)
RRO: 104681074(MCL1)
RBB: 108533266(MCL1)
CJC: 100406790(MCL1)
SBQ: 101046604(MCL1)
MMU: 17210(Mcl1)
RNO: 60430(Mcl1)
CGE: 100764237(Mcl1)
NGI: 103729108(Mcl1)
HGL: 101724340(Mcl1)
CCAN: 109681197(Mcl1)
OCU: 100359222(MCL1)
TUP: 102472561(MCL1)
CFA: 403537(MCL1)
AML: 100484433(MCL1)
UMR: 103667602(MCL1)
ORO: 101368348(MCL1) 101376217
FCA: 493970(MCL1)
PTG: 102965985(MCL1)
AJU: 106986653(MCL1)
BTA: 788087(MCL1)
BOM: 102277523 102283384(MCL1)
BIU: 109555382(MCL1) 109564155
PHD: 102335865(MCL1)
CHX: 102185798(MCL1)
OAS: 554329(MCL1)
SSC: 397648(MCL1)
CFR: 102509345(MCL1)
CDK: 105103187(MCL1)
BACU: 103006100(MCL1)
LVE: 103090946(MCL1)
OOR: 101289701(MCL1)
ECB: 100054765(MCL1)
EPZ: 103547666(MCL1)
EAI: 106846539(MCL1)
MYB: 102262272(MCL1)
MYD: 102766301(MCL1)
HAI: 109372291(MCL1)
RSS: 109451606(MCL1)
PALE: 102884014(MCL1)
LAV: 100676317(MCL1)
TMU: 101350934
MDO: 100017262(MCL1)
SHR: 100928648(MCL1)
GGA: 395674(MCL1)
MGP: 100540044(MCL1)
CJO: 107324527(MCL1)
APLA: 101803270(MCL1)
ACYG: 106029353
GFR: 102044096(MCL1)
FAB: 101817366(MCL1)
PHI: 102111555(MCL1)
PMAJ: 107198998(MCL1)
CCW: 104683526(MCL1)
FCH: 102058939(MCL1)
CLV: 102097620(MCL1)
EGZ: 104134875(MCL1)
AAM: 106495154(MCL1)
ASN: 102377228(MCL1)
AMJ: 102565309(MCL1)
PSS: 102460228(MCL1)
CMY: 102947037(MCL1)
CPIC: 101937549(MCL1) 101950886
ACS: 100556744(mcl1)
PVT: 110081542(MCL1)
PBI: 103056794(MCL1)
GJA: 107120546(MCL1)
XLA: 100192362(mcl1.L) 108700339(mcl1.S)
XTR: 100038211(mcl1)
NPR: 108789796(MCL1)
DRE: 58122(mcl1a)
TRU: 101069436(mcl1)
NCC: 104944908
MZE: 101488044
OLA: 101165916
XMA: 102230859
PRET: 103477645
NFU: 107379220
LCF: 108883179
BPEC: 110162674
ELS: 105031245
LCM: 102350724(MCL1)
SKO: 100377406
OBI: 106869231
LAK: 106168952
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Bingle CD, Craig RW, Swales BM, Singleton V, Zhou P, Whyte MK
  Title
Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death.
  Journal
J Biol Chem 275:22136-46 (2000)
DOI:10.1074/jbc.M909572199
Reference
  Authors
Fujise K, Zhang D, Liu J, Yeh ET
  Title
Regulation of apoptosis and cell cycle progression by MCL1. Differential role of proliferating cell nuclear antigen.
  Journal
J Biol Chem 275:39458-65 (2000)
DOI:10.1074/jbc.M006626200
  Sequence
[hsa:4170]

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