KEGG   ORTHOLOGY: K02580Help
Entry
K02580                      KO                                     

Name
NFKB1
Definition
nuclear factor NF-kappa-B p105 subunit
Pathway
MAPK signaling pathway
Ras signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Osteoclast differentiation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
T cell receptor signaling pathway
B cell receptor signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Prolactin signaling pathway
Adipocytokine signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Cocaine addiction
Epithelial cell signaling in Helicobacter pylori infection
Shigellosis
Salmonella infection
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Tuberculosis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Transcriptional misregulation in cancer
Viral carcinogenesis
MicroRNAs in cancer
Pancreatic cancer
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04010 MAPK signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04064 NF-kappa B signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04668 TNF signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04066 HIF-1 signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04024 cAMP signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04151 PI3K-Akt signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04621 NOD-like receptor signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04622 RIG-I-like receptor signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04623 Cytosolic DNA-sensing pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04660 T cell receptor signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04662 B cell receptor signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04062 Chemokine signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
  Endocrine system
   04920 Adipocytokine signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   04917 Prolactin signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
  Nervous system
   04722 Neurotrophin signaling pathway
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
  Development
   04380 Osteoclast differentiation
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05202 Transcriptional misregulation in cancers
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05206 MicroRNAs in cancer
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05203 Viral carcinogenesis
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05212 Pancreatic cancer
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05221 Acute myeloid leukemia
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05220 Chronic myeloid leukemia
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05215 Prostate cancer
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05222 Small cell lung cancer
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
  Substance dependence
   05030 Cocaine addiction
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05132 Salmonella infection
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05131 Shigellosis
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05133 Pertussis
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05134 Legionellosis
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05152 Tuberculosis
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05166 HTLV-I infection
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05162 Measles
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05164 Influenza A
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05161 Hepatitis B
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05160 Hepatitis C
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05168 Herpes simplex infection
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05169 Epstein-Barr virus infection
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05146 Amoebiasis
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05145 Toxoplasmosis
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05140 Leishmaniasis
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
   05142 Chagas disease (American trypanosomiasis)
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
BRITE hierarchy
Genes
HSA: 
4790(NFKB1)
PTR: 
461406(NFKB1)
PPS: 
100979341(NFKB1)
GGO: 
101153465(NFKB1)
PON: 
100461595(NFKB1)
MCC: 
710324(NFKB1)
MCF: 
102138273(NFKB1)
MMU: 
18033(Nfkb1)
RNO: 
81736(Nfkb1)
CGE: 
100770607(Nfkb1)
HGL: 
101696485(Nfkb1)
TUP: 
102487413(NFKB1)
CFA: 
442859(NFKB1)
AML: 
100467906(NFKB)
FCA: 
100142683(NFKB1)
PTG: 
102964232(NFKB1)
BTA: 
616115(NFKB1)
BOM: 
102286969(NFKB1)
PHD: 
102316422(NFKB1)
CHX: 
102175660(NFKB1)
SSC: 
751869(NFKB1)
CFR: 
102505905(NFKB1)
BACU: 
102999230(NFKB1)
LVE: 
103068644(NFKB1)
ECB: 
100067894(NFKB1)
MYB: 
102255251(NFKB1)
MYD: 
102770715(NFKB1)
PALE: 
102880692(NFKB1)
MDO: 
100014446(NFKB1)
SHR: 
OAA: 
GGA: 
396033(NFKB1)
MGP: 
TGU: 
100221542(NFKB1)
FAB: 
101815528(NFKB1)
PHI: 
102106412(NFKB1)
APLA: 
101803431(NFKB1)
FPG: 
101920008(NFKB1)
FCH: 
102049462(NFKB1)
CLV: 
102086078(NFKB1)
ASN: 
102369946(NFKB1)
AMJ: 
102558052(NFKB1)
PSS: 
102457132(NFKB1)
CMY: 
102944582(NFKB1)
PBI: 
103049819(NFKB1)
XLA: 
447632(nfkb1)
XTR: 
100486083(nfkb1)
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
CIN: 
778692(nfkbp105)
SPU: 
373533(NFkB)
NVE: 
AQU: 
100616089(Nfkb)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Oeckinghaus A, Ghosh S
  Title
The NF-kappaB family of transcription factors and its regulation.
  Journal
Cold Spring Harb Perspect Biol 1:a000034 (2009)

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