KEGG   ORTHOLOGY: K02861Help
Entry
K02861                      KO                                     

Name
RIPK1, RIP1
Definition
receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
Pathway
NF-kappa B signaling pathway
Apoptosis
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
TNF signaling pathway
Hepatitis C
Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
   04668 TNF signaling pathway
    K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
   04622 RIG-I-like receptor signaling pathway
    K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
   04623 Cytosolic DNA-sensing pathway
    K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
 Human Diseases
  Infectious diseases
   05160 Hepatitis C
    K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
   05169 Epstein-Barr virus infection
    K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: TKL group
  RIPK family [OT]
   K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1
BRITE hierarchy
Genes
HSA: 
8737(RIPK1)
PTR: 
462397(RIPK1)
PPS: 
100991521(RIPK1)
GGO: 
101153833(RIPK1)
PON: 
100449028(RIPK1)
NLE: 
100599272(RIPK1)
MCC: 
708013(RIPK1)
MCF: 
CJC: 
100415562(RIPK1)
MMU: 
19766(Ripk1)
RNO: 
306886(Ripk1)
CGE: 
100761116(Ripk1)
HGL: 
101696605(Ripk1)
TUP: 
102502622(RIPK1)
CFA: 
102152063(RIPK1)
AML: 
100469872(RIPK1)
UMR: 
FCA: 
101087663(RIPK1)
PTG: 
102964459(RIPK1)
BTA: 
504727(RIPK1)
BOM: 
102279783(RIPK1)
PHD: 
102338792(RIPK1)
CHX: 
102178407(RIPK1)
OAS: 
101110186(RIPK1)
SSC: 
100524751(RIPK1)
CFR: 
102516401(RIPK1)
BACU: 
103004292(RIPK1)
LVE: 
ECB: 
100058015(RIPK1)
MYB: 
102245425(RIPK1)
MYD: 
102770973(RIPK1)
PALE: 
102885162(RIPK1)
MDO: 
100028597(RIPK1)
SHR: 
100914177(RIPK1)
OAA: 
100079746(RIPK1)
GGA: 
378921(RIPK1)
MGP: 
APLA: 
101801990(RIPK1)
TGU: 
100230522(RIPK1)
FAB: 
101806351(RIPK1)
PHI: 
102112432(RIPK1)
FPG: 
101913441(RIPK1)
FCH: 
102058820(RIPK1)
CLV: 
102093314(RIPK1)
ASN: 
102367941(RIPK1)
AMJ: 
102572936(RIPK1)
PSS: 
102455858(RIPK1)
CMY: 
102944603(RIPK1)
ACS: 
100556206(ripk1)
PBI: 
103062047(RIPK1)
XLA: 
734234(ripk1)
XTR: 
779958(ripk1)
DRE: 
567460(ripk1l)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102363596(RIPK1)
CMK: 
103176210(ripk1)
CIN: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M, Chan FK
  Title
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.
  Journal
Cell 137:1112-23 (2009)
  Sequence
[hsa:8737]

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