KEGG   ORTHOLOGY: K03006Help
Entry
K03006                      KO                                     

Name
RPB1, POLR2A
Definition
DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
Pathway
ko00230  Purine metabolism
ko00240  Pyrimidine metabolism
ko01100  Metabolic pathways
ko03020  RNA polymerase
ko05016  Huntington's disease
ko05168  Herpes simplex infection
ko05169  Epstein-Barr virus infection
Module
M00180  RNA polymerase II, eukaryotes
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
   00240 Pyrimidine metabolism
    K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
 Genetic Information Processing
  Transcription
   03020 RNA polymerase
    K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
 Human Diseases
  Neurodegenerative diseases
   05016 Huntington's disease
    K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
  Infectious diseases
   05168 Herpes simplex infection
    K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
   05169 Epstein-Barr virus infection
    K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   RNA polymerase
    M00180  RNA polymerase II, eukaryotes
     K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.6  DNA-directed RNA polymerase
     K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Core subunits
     K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1
BRITE hierarchy
Other DBs
RN: R00435 R00441 R00442 R00443
COG: COG0086
GO: 0003899
Genes
HSA: 5430(POLR2A)
PTR: 454463(POLR2A)
PPS: 100978542(POLR2A)
GGO: 101124852 101125439(POLR2A) 101126759 109025070
PON: 100432084(POLR2A)
NLE: 100602704 100607400(POLR2A) 105739221
MCC: 721865(POLR2A)
MCF: 101866538(POLR2A) 102117738
CSAB: 103235459 103241040 103242561(POLR2A) 103244018
RRO: 104661647(POLR2A) 104665965 104669448
RBB: 108514411(POLR2A)
SBQ: 101037169(POLR2A) 104652524
MMU: 20020(Polr2a)
RNO: 363633(Polr2a)
NGI: 103732687 103752129(Polr2a)
HGL: 101725588(Polr2a)
CCAN: 109674720(Polr2a) 109675799
TUP: 102483652(POLR2A)
CFA: 479483(POLR2A)
AML: 100466109(POLR2A)
UMR: 103660476(POLR2A) 103662796
ORO: 101366669(POLR2A)
FCA: 101098500(POLR2A)
PTG: 102963688(POLR2A)
AJU: 106972432(POLR2A)
BTA: 282312(POLR2A)
BOM: 102267367(POLR2A)
BIU: 109573243 109573647(POLR2A)
PHD: 102336826(POLR2A)
CHX: 102187892(POLR2A)
OAS: 100144762(POLR2A)
SSC: 100737040(POLR2A)
CFR: 102521198(POLR2A)
CDK: 105103024(POLR2A)
BACU: 103005752(POLR2A)
LVE: 103081078 103085062(POLR2A)
OOR: 101289878(POLR2A)
ECB: 100072997(POLR2A)
EPZ: 103557717(POLR2A) 103566557
EAI: 106844204(POLR2A)
MYB: 102240177(POLR2A) 102248599
MYD: 102755359(POLR2A)
HAI: 109394669(POLR2A)
RSS: 109440163 109454459(POLR2A)
PALE: 102885614(POLR2A)
LAV: 100662030(POLR2A)
TMU: 101354753
MDO: 100014728(POLR2A)
SHR: 100926404(POLR2A)
OAA: 100086954(POLR2A)
GFR: 102043834
PHI: 102114631(POLR2A) 106628779
FPG: 101917042(POLR2A) 106112884
FCH: 102050838
CLV: 110363770
EGZ: 104129623
ASN: 102378270(POLR2A)
AMJ: 102572150(POLR2A)
PSS: 102448760
CMY: 102942345
CPIC: 101934161(POLR2A)
ACS: 100555559 100561860(polr2a)
PVT: 110087752(POLR2A)
PBI: 103060884(POLR2A)
GJA: 107119815(POLR2A) 107121070
XLA: 108703583(polr2a.S) 108711801 108711840(polr2a.L)
DRE: 553347(polr2a)
CCAR: 109056007(polr2a) 109067075
IPU: 108272125 108273729(polr2a)
TRU: 101067103(polr2a)
NCC: 104945449(polr2a)
MZE: 101464637(polr2a)
OLA: 101160848(polr2a)
XMA: 102226500(polr2a)
PRET: 103480466(polr2a)
CSEM: 103387258(polr2a)
HCQ: 109508358(polr2a)
SFM: 108923135(polr2a) 108933825
LCM: 102363493
CIN: 100177272
SPU: 583794
APLC: 110980806
DME: Dmel_CG1554(RpII215)
DPO: Dpse_GA13798(Dpse_RpII215)
DER: Dere_GG18851(Dere_RpII215)
DSI: Dsimw501_GD15986(Dsim_GD15986)
DYA: Dyak_GE17292(Dyak_RpII215)
AAG: 23687783
AME: 550829(Polii)
BIM: 100742572
BTER: 100643011
SOC: 105203889
ACEP: 105620252
PBAR: 105426788
HST: 105187653
LHU: 105677199
PGC: 109862221
NVI: 100116776(POLII)
PRAP: 111004072
CEL: CELE_F36A4.7(ama-1)
CBR: CBG05355(Cbr-rpb-1)
BMY: Bm1_34315
TSP: Tsp_05375
CRG: 105344236
SHX: MS3_04490
EPA: 110246041
HMG: 100204515 101238056(polr2a)
ATH: AT4G35800(NRPB1)
CPAP: 110822512
TCC: 18610701
LJA: Lj2g3v1648020.1(Lj2g3v1648020.1) Lj2g3v1648040.1(Lj2g3v1648040.1) Lj2g3v1659630.1(Lj2g3v1659630.1) Lj2g3v3109510.1(Lj2g3v3109510.1) Lj4g3v2296000.1(Lj4g3v2296000.1) Lj6g3v1093470.1(Lj6g3v1093470.1)
PPER: 18769771
PMUM: 103340377
PAVI: 110761372
CSV: 101220606
CMO: 103490666
MCHA: 111014830
RCU: 8267704
INI: 109177654
NNU: 104604309(RPB1)
DOSA: Os05t0151000-00(Os05g0151000)
OBR: 102715133
ATS: 109733104(LOC109733104) 109733730(LOC109733730) 109733985(LOC109733985) 109738132(LOC109738132) 109741117(LOC109741117) 109748481(LOC109748481) 109760995(LOC109760995) 109771740(LOC109771740) 109784772(LOC109784772) 109784773(LOC109784773) 109786615(LOC109786615)
ZMA: 541967
PDA: 103718915
DCT: 110095028
AOF: 109827408
ATR: 105420618 18424189(RPB1)
CRE: CHLREDRAFT_196948(RPB1)
APRO: F751_1389
SCE: YDL140C(RPO21)
ERC: Ecym_8065
KMX: KLMA_60512(RPB1)
NCS: NCAS_0A13900(NCAS0A13900)
NDI: NDAI_0A02130(NDAI0A02130)
TPF: TPHA_0A03070(TPHA0A03070)
TBL: TBLA_0F02170(TBLA0F02170)
TDL: TDEL_0C02320(TDEL0C02320)
KAF: KAFR_0B01060(KAFR0B01060)
PIC: PICST_75374(RPO21)
CAL: CAALFM_CR10680WA(RPO21)
CAUR: QG37_04197
SLB: AWJ20_3261(RPO21)
NTE: NEUTE1DRAFT47767(NEUTE1DRAFT_47767) NEUTE1DRAFT70543(NEUTE1DRAFT_70543)
MGR: MGG_04652
MAW: MAC_07408
MAJ: MAA_00658
CMT: CCM_05485
MBE: MBM_03515
ANI: AN0809.2
ANG: ANI_1_3202014(An01g12710)
ABE: ARB_00027
TVE: TRV_02753
SPO: SPBC28F2.12(rpb1)
CNE: CNE03720
CNB: CNBE3710
ABP: AGABI1DRAFT116765(AGABI1DRAFT_116765) AGABI1DRAFT65857(AGABI1DRAFT_65857)
ABV: AGABI2DRAFT195511(AGABI2DRAFT_195511) AGABI2DRAFT215454(AGABI2DRAFT_215454)
MGL: MGL_2782
DDI: DDB_G0279193(rpb1)
DFA: DFA_09469(rpb1)
EHI: EHI_121760(147.t00005)
PYO: PY17X_0810200(PY03187)
PCB: PCHAS_080730(PC000499.01.0)
TAN: TA03235
TPV: TP03_0185
BBO: BBOV_I003360(19.m02399)
CPV: cgd3_2620
TGO: TGME49_225260(POLR2A)
SMIN: v1.2.018632.t1(symbB.v1.2.018632.t1) v1.2.036200.t1(symbB.v1.2.036200.t1)
FCY: FRACYDRAFT_183150(RNA_pol)
TPS: THAPSDRAFT_168(RPB1)
TCR: 509011.20
LMA: LMJF_31_2610(RPOIILS)
LIF: LINJ_31_2680(RPOIILS)
VG: 10963889(WIV_gp167) 11257036(mg373) 12977914(11R) 14445391(H012_gp622) 1497295(LCDV1gp007) 15766152(PGCG_00263) 16414381(042R) 16512858(pdul_cds_295) 16605586(psal_cds_246) 1733004(IIV6gp172) 18266394(pv_366-368) 18501236(041R) 18501416(044R) 18501593(043R) 18938278(DH26_gp117) 19738704(120R) 20041646(JO84_gp233) 20041750(JO84_gp155) 22220328(NP1450L) 23463173(TW95_gp1522) 25479125(AMQ81_gp076) 25812737(ml_310) 26049265(ceV_398) 26281639(ATL82_gp007) 26683634(AV955_gp089) 28218350(ORF8) 28619867(BGV90_gp007) 2943447(LDVICp190) 2947780(FV3gorf8R) 30523163(BQ3484_210) 30902737(BZK12_gp161) 31050597(B1750_gp011) 3197022(ORF104L) 32290704(B9W72_gp295) 3654696(EhV064) 3678174(ATVp06) 4156234(MIV090L) 4306175(ORF008) 5076030(HVAV3e_gp011) 5141657(TNAV2c_gp042) 935304(Isaknvgp028) 9887771(crov368) 9925132(R501)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
PMID:9852112
  Authors
Kershnar E, Wu SY, Chiang CM
  Title
Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.
  Journal
J Biol Chem 273:34444-53 (1998)
DOI:10.1074/jbc.273.51.34444
  Sequence
[hsa:5430]

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