KEGG   ORTHOLOGY: K03010Help
Entry
K03010                      KO                                     

Name
RPB2, POLR2B
Definition
DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
Pathway
ko00230  Purine metabolism
ko00240  Pyrimidine metabolism
ko01100  Metabolic pathways
ko03020  RNA polymerase
ko05016  Huntington's disease
ko05169  Epstein-Barr virus infection
Module
M00180  RNA polymerase II, eukaryotes
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2
   00240 Pyrimidine metabolism
    K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2
 Genetic Information Processing
  Transcription
   03020 RNA polymerase
    K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2
 Human Diseases
  Neurodegenerative diseases
   05016 Huntington's disease
    K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2
  Infectious diseases
   05169 Epstein-Barr virus infection
    K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   RNA polymerase
    M00180  RNA polymerase II, eukaryotes
     K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.6  DNA-directed RNA polymerase
     K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Core subunits
     K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2
BRITE hierarchy
Other DBs
RN: R00435 R00441 R00442 R00443
COG: COG0085
GO: 0003899
Genes
HSA: 5431(POLR2B)
PTR: 461305(POLR2B)
PPS: 100968738(POLR2B)
GGO: 101143816(POLR2B)
PON: 100446677(POLR2B)
NLE: 100584058(POLR2B)
MCC: 694664(POLR2B)
MCF: 101926699(POLR2B)
CSAB: 103235632(POLR2B)
RRO: 104682709(POLR2B)
RBB: 108513476(POLR2B)
CJC: 100398671(POLR2B)
SBQ: 101031275(POLR2B)
MMU: 231329(Polr2b)
RNO: 289561(Polr2b)
CGE: 100755901(Polr2b) 103159043
NGI: 103734370(Polr2b)
HGL: 101716957(Polr2b)
CCAN: 109691660(Polr2b)
OCU: 100348087(POLR2B)
TUP: 102489094(POLR2B)
CFA: 475152(POLR2B)
AML: 100483838(POLR2B)
UMR: 103672816(POLR2B)
ORO: 101383255(POLR2B)
FCA: 101082819(POLR2B)
PTG: 102949543(POLR2B)
AJU: 106971661(POLR2B)
BTA: 538184(POLR2B)
BOM: 102278532(POLR2B)
BIU: 109560501(POLR2B)
PHD: 102318820(POLR2B)
CHX: 102181376(POLR2B)
OAS: 101111368(POLR2B)
SSC: 397001(POLR2B)
CFR: 102506075(POLR2B)
CDK: 105091802(POLR2B)
BACU: 103005000(POLR2B)
LVE: 103068533(POLR2B)
OOR: 101284735(POLR2B)
ECB: 100053708(POLR2B)
EPZ: 103556479(POLR2B)
EAI: 106841688(POLR2B)
MYB: 102246104 102262116(POLR2B)
HAI: 109394371(POLR2B)
RSS: 109440020 109451696(POLR2B)
PALE: 102879872(POLR2B)
LAV: 100672166(POLR2B)
TMU: 101344562
MDO: 100012197(POLR2B)
SHR: 100921014(POLR2B)
OAA: 100092521(POLR2B)
GGA: 422621(POLR2B)
MGP: 100548897(POLR2B)
CJO: 107313401(POLR2B)
APLA: 101792149(POLR2B)
ACYG: 106046088(POLR2B)
TGU: 100220604(POLR2B)
GFR: 102044948(POLR2B)
FAB: 101814603(POLR2B)
PHI: 102107563(POLR2B)
PMAJ: 107203204(POLR2B)
CCW: 104697209(POLR2B)
FPG: 101911796(POLR2B)
FCH: 102055075(POLR2B)
CLV: 102088079(POLR2B)
EGZ: 104122670(POLR2B)
AAM: 106495852(POLR2B)
ASN: 102377984(POLR2B)
AMJ: 102574695(POLR2B)
PSS: 102445005(POLR2B)
CMY: 102931328(POLR2B)
CPIC: 101946265(POLR2B)
ACS: 100560133(polr2b)
PVT: 110090994(POLR2B)
PBI: 103055368(POLR2B)
GJA: 107106788(POLR2B) 107125350
XLA: 108712074 398890(polr2b.L)
XTR: 100380205(polr2b)
NPR: 108791660(POLR2B)
DRE: 100149268(polr2b)
IPU: 108278578(polr2b)
AMEX: 103034649(polr2b)
TRU: 101064446(polr2b) 101074162
LCO: 104939446(polr2b)
MZE: 101470057(polr2b)
OLA: 101166780(polr2b)
XMA: 102217972(polr2b)
PRET: 103471798(polr2b)
NFU: 107381208(polr2b)
CSEM: 103390778(polr2b)
LCF: 108891802(polr2b)
HCQ: 109508323(polr2b)
BPEC: 110153111(polr2b)
SASA: 100380395(rpb2) 106604641
ELS: 105007541(polr2b)
SFM: 108938795(polr2b)
LCM: 102365212(POLR2B)
CMK: 103177668(polr2b)
CIN: 100181952(polr2b)
SPU: 584422
APLC: 110979844
SKO: 100377945
DME: Dmel_CG3180(RpII140)
DSI: Dsimw501_GD18948(Dsim_GD18948)
DVI: Dvir_GJ24629(Dvir_RpII140)
MDE: 101890053
AAG: 23687633
AME: 552156(RpII140)
BIM: 100750174
BTER: 100642622
AEC: 105148984
ACEP: 105622040
PBAR: 105428806
HST: 105181898
CFO: 105250022
LHU: 105674410
PGC: 109856178
TCA: 663520
DPA: 109545413
BMOR: 101746067
PMAC: 106713319
PRAP: 111002501
PXY: 105387798
API: 100168370
DNX: 107169069
ZNE: 110831776
TUT: 107361736
CEL: CELE_C26E6.4(rpb-2)
CBR: CBG18197(Cbr-rpb-2)
BMY: Bm1_45495
TSP: Tsp_09661
CRG: 105343101
MYI: 110452053
OBI: 106874492
SHX: MS3_09303
EPA: 110240663
ADF: 107349326
HMG: 100208869(polr2b)
ATH: AT4G21710(NRPB2)
CRB: 17880293
CPAP: 110817850
TCC: 18596855
GRA: 105772811
GHI: 107960207
DZI: 111280340
EGR: 104445284
CCAJ: 109803307
CAM: 101504170
ADU: 107468283
AIP: 107622567
LJA: Lj6g3v2041910.1(Lj6g3v2041910.1)
FVE: 101295402
PPER: 18778996
PMUM: 103324762
PAVI: 110766738
CSV: 101205163
CMO: 103484522
MCHA: 111012507
CMAX: 111478551
CMOS: 111433090
CPEP: 111803581
RCU: 8279501
JCU: 105649538
HBR: 110648006
POP: 7477407
JRE: 108990620
VVI: 100252267(RPB2)
SLY: 100736502(RPB2-2) 544278(rpb2)
SPEN: 107011155
DCR: 108204225
BVG: 104900705
SOE: 110788080
NNU: 104587142(RPB2)
OSA: 4333571
DOSA: Os03t0646800-01(Os03g0646800)
OBR: 102718250
BDI: 100838357
ATS: 109785353(LOC109785353) 109786605(LOC109786605)
SBI: 8062207
SITA: 101780789
PDA: 103715429
EGU: 105044174
MUS: 103999650
DCT: 110096277
ATR: 18448921(RPB2)
CRE: CHLREDRAFT_186432(RPB2)
APRO: F751_4378
SCE: YOR151C(RPB2)
ERC: Ecym_4538
KMX: KLMA_50187(RPB2)
NCS: NCAS_0H02400(NCAS0H02400)
NDI: NDAI_0C01250(NDAI0C01250)
TPF: TPHA_0J02910(TPHA0J02910)
TBL: TBLA_0A02460(TBLA0A02460)
TDL: TDEL_0A03610(TDEL0A03610)
KAF: KAFR_0E02450(KAFR0E02450)
PIC: PICST_34146(RPB140)
SPAA: SPAPADRAFT_53113(RPB2)
CAL: CAALFM_C101590CA(CaO19.3349)
CAUR: QG37_03091
SLB: AWJ20_2667(RPB2)
NCR: NCU05120
NTE: NEUTE1DRAFT124967(NEUTE1DRAFT_124967)
MGR: MGG_04714
TRE: TRIREDRAFT_79225(rpb2)
MAW: MAC_02463
MAJ: MAA_00336
CMT: CCM_06694
MBE: MBM_04681
ANI: AN9120.2
ANG: ANI_1_104104(An12g00720)
ABE: ARB_06116
TVE: TRV_00102
PTE: PTT_11005
SPO: SPAC23G3.01(rpb2)
CNE: CND03540
CNB: CNBD2790
ABP: AGABI1DRAFT117576(AGABI1DRAFT_117576)
ABV: AGABI2DRAFT113824(AGABI2DRAFT_113824)
MGL: MGL_0889
DDI: DDB_G0288257(rpb2)
DFA: DFA_03939(rpb2)
EHI: EHI_022940(81.t00015)
PYO: PY17X_0312900(PY01115)
PCB: PCHAS_031450(PC000741.00.0)
TAN: TA07925
TPV: TP04_0340
BBO: BBOV_II002050(18.m06162)
CPV: cgd7_3720
SMIN: v1.2.010767.t1(symbB.v1.2.010767.t1) v1.2.028322.t1(symbB.v1.2.028322.t1) v1.2.028323.t1(symbB.v1.2.028323.t1)
TPS: THAPSDRAFT_40925(RPB21)
SPAR: SPRG_07858
TCR: 509951.49
VG: 10399617(rpc2) 10963836(WIV_gp114) 12977927(58R) 1497301(LCDV1gp013) 15766097(PGCG_00208) 15766117(PGCG_00228) 16414503(164R) 16512637(pdul_cds_410) 16605810(psal_cds_363) 1733408(IIV6gp424) 18266270(pv_242) 18501367(173R) 18501547(175R) 18501721(171R) 19738779(195R) 20041727(JO84_gp253) 21012043(MEL_022) 22220435(EP1242L) 25479171(AMQ81_gp122) 26049143(ceV_276) 26049155(ceV_288) 26281675(ATL82_gp043) 27111958(A3303_gp045) 27924385(A9K97_gp466) 28218309(ORF49) 28619906(BGV90_gp046) 2947762(FV3gorf62L) 29674579(GMAR_ORF274) 2979160(LDVICp025) 30523324(BQ3484_355) 30902636(BZK12_gp060) 31051022(B1750_gp436) 31910245(BNJ_00362) 3197077(ORF073L) 32290851(B9W72_gp044) 3654845(EhV434) 3678211(ATVp44) 4156258(MIV009R) 8746261(MAR_ORF023) 935305(Isaknvgp034) 9887626(crov224)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
PMID:9852112
  Authors
Kershnar E, Wu SY, Chiang CM
  Title
Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.
  Journal
J Biol Chem 273:34444-53 (1998)
DOI:10.1074/jbc.273.51.34444
  Sequence
[hsa:5431]

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