KEGG   ORTHOLOGY: K03158Help
Entry
K03158                      KO                                     

Name
TNFRSF1A, TNFR1
Definition
tumor necrosis factor receptor superfamily member 1A
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
NF-kappa B signaling pathway
Sphingolipid signaling pathway
mTOR signaling pathway
Apoptosis
Apoptosis - multiple species
Osteoclast differentiation
TNF signaling pathway
Adipocytokine signaling pathway
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
HTLV-I infection
Herpes simplex infection
Disease
H00912  
Tumor necrosis factor receptor-associated periodic syndrome (TRAPS)
H01490  
Multiple sclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   04064 NF-kappa B signaling pathway
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   04668 TNF signaling pathway
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   04071 Sphingolipid signaling pathway
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   04150 mTOR signaling pathway
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   04215 Apoptosis - multiple species
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
 Organismal Systems
  Endocrine system
   04920 Adipocytokine signaling pathway
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
  Development
   04380 Osteoclast differentiation
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   05014 Amyotrophic lateral sclerosis (ALS)
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   04931 Insulin resistance
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
  Infectious diseases
   05152 Tuberculosis
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   05166 HTLV-I infection
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   05164 Influenza A
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   05160 Hepatitis C
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   05168 Herpes simplex infection
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   05145 Toxoplasmosis
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
   05142 Chagas disease (American trypanosomiasis)
    K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
Cytokine receptors [BR:ko04050]
 TNF receptor family
  K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
Cellular antigens [BR:ko04090]
 Proteins
  K03158  CD120a, TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
7132(TNFRSF1A)
PTR: 
466934(TNFRSF1A)
PPS: 
100983212(TNFRSF1A)
GGO: 
101149216(TNFRSF1A)
PON: 
100438667(TNFRSF1A)
NLE: 
100581749(TNFRSF1A)
MCC: 
722033(TNFRSF1A)
MCF: 
102135285(TNFRSF1A)
RRO: 
104680127(TNFRSF1A)
CJC: 
100397418(TNFRSF1A)
MMU: 
21937(Tnfrsf1a)
RNO: 
25625(Tnfrsf1a)
CGE: 
100765017(Tnfrsf1a)
NGI: 
103727530(Tnfrsf1a)
HGL: 
101698980(Tnfrsf1a)
OCU: 
100346106(TNFRSF1A)
TUP: 
102493692(TNFRSF1A)
CFA: 
403634(TNFRSF1A)
AML: 
100479926(TNFRSF1A)
UMR: 
103656234(TNFRSF1A)
FCA: 
493957(TNFRSF1A)
PTG: 
102956793(TNFRSF1A)
BTA: 
282527(TNFRSF1A)
BOM: 
102285873(TNFRSF1A)
PHD: 
102331960(TNFRSF1A)
CHX: 
102190310(TNFRSF1A)
OAS: 
100135698(TNFRSF1A)
SSC: 
397020(TNFRSF1A)
CFR: 
102508884(TNFRSF1A)
BACU: 
103016474(TNFRSF1A)
LVE: 
103072461(TNFRSF1A)
ECB: 
100059548(TNFRSF1A)
MYB: 
102251038(TNFRSF1A)
MYD: 
102768884(TNFRSF1A)
PALE: 
102885752(TNFRSF1A)
MDO: 
103104450(TNFRSF1A)
SHR: 
100919788(TNFRSF1A)
OAA: 
100085735(TNFRSF1A)
GGA: 
418325(TNFRSF1A)
MGP: 
100544064(TNFRSF1A)
CJO: 
107319582(TNFRSF1A)
APLA: 
101801004(TNFRSF1A)
TGU: 
GFR: 
102036131(TNFRSF1A)
FAB: 
101821296(TNFRSF1A)
PHI: 
102104037(TNFRSF1A)
CCW: 
104687033(TNFRSF1A)
FPG: 
101917376(TNFRSF1A)
FCH: 
102057894(TNFRSF1A)
CLV: 
AAM: 
106497278(TNFRSF1A)
ASN: 
AMJ: 
102560352(TNFRSF1A)
PSS: 
102445357(TNFRSF1A)
CMY: 
ACS: 
PBI: 
GJA: 
XLA: 
100137626(tnfrsf1a)
XTR: 
100144930(tnfrsf1a)
DRE: 
406471(tnfrsf1a)
TRU: 
101071351(tnfrsf1a)
MZE: 
OLA: 
105355952(tnfrsf1a)
XMA: 
102237252(tnfrsf1a)
LCM: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2158862
  Authors
Loetscher H, Pan YC, Lahm HW, Gentz R, Brockhaus M, Tabuchi H, Lesslauer W
  Title
Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor.
  Journal
Cell 61:351-9 (1990)
  Sequence
[hsa:7132]
Reference
PMID:1849278
  Authors
Lewis M, Tartaglia LA, Lee A, Bennett GL, Rice GC, Wong GH, Chen EY, Goeddel DV
  Title
Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.
  Journal
Proc Natl Acad Sci U S A 88:2830-4 (1991)
  Sequence
[mmu:21937]

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