KEGG   ORTHOLOGY: K03161Help
Entry
K03161                      KO                                     

Name
TNFSF5, CD40L
Definition
tumor necrosis factor ligand superfamily member 5
Pathway
Cytokine-cytokine receptor interaction
NF-kappa B signaling pathway
Cell adhesion molecules (CAMs)
T cell receptor signaling pathway
Intestinal immune network for IgA production
Malaria
Toxoplasmosis
Asthma
Autoimmune thyroid disease
Systemic lupus erythematosus
Allograft rejection
Primary immunodeficiency
Viral myocarditis
Disease
H00093  
Combined immunodeficiencies (CIDs)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
   04514 Cell adhesion molecules (CAMs)
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
   04672 Intestinal immune network for IgA production
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
 Human Diseases
  Immune diseases
   05310 Asthma
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
   05322 Systemic lupus erythematosus
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
   05320 Autoimmune thyroid disease
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
   05330 Allograft rejection
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
   05340 Primary immunodeficiency
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
  Cardiovascular diseases
   05416 Viral myocarditis
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
  Infectious diseases
   05144 Malaria
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
   05145 Toxoplasmosis
    K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
Cytokines [BR:ko04052]
 TNF family
  K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
Cell adhesion molecules and their ligands [BR:ko04516]
 2. Integrin Family
  Beta1 integrins
   VLA-5
    ITGB1; integrin beta 1
     K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
  Beta2 integrins
   CR3, Mac-1
    ITGB2; integrin beta 2
     K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
  Beta3 integrins
   alpha IIb  beta 3
    ITGB3; integrin beta 3
     K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
 7. Others
  TNFRSF5, CD40; tumor necrosis factor receptor superfamily, member 5
   K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
Cellular antigens [BR:ko04090]
 Proteins
  K03161  CD154, CD40LG; tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
BRITE hierarchy
Other DBs
Genes
HSA: 
959(CD40LG)
PTR: 
473802(CD40LG)
PPS: 
100975410(CD40LG)
GGO: 
101152672(CD40LG)
PON: 
100434130(CD40LG)
MCC: 
574160(CD40LG)
MCF: 
102138630(CD40LG)
MMU: 
21947(Cd40lg)
RNO: 
84349(Cd40lg)
CGE: 
HGL: 
101700616(Cd40lg)
TUP: 
102488619(CD40LG)
CFA: 
403468(CD40LG)
AML: 
FCA: 
493850(CD40LG)
BTA: 
282387(CD40LG)
BOM: 
102269787(CD40LG)
PHD: 
102320409(CD40LG)
CHX: 
102172335(CD40LG)
SSC: 
397231(CD40LG)
CFR: 
102520018(CD40LG)
ECB: 
100054624(CD40LG)
MYB: 
102255985(CD40LG)
MDO: 
SHR: 
100918070(CD40LG)
OAA: 
GGA: 
395485(CD40LG)
MGP: 
TGU: 
100231712(CD40LG)
FAB: 
101808143(CD40LG)
PHI: 
102107724(CD40LG)
APLA: 
101789598(CD40LG)
FPG: 
101911204(CD40LG)
FCH: 
102059509(CD40LG)
CLV: 
102086646(CD40LG)
ASN: 
102381504(CD40LG)
PSS: 
102447555(CD40LG)
ACS: 
XTR: 
100489038(cd40lg)
DRE: 
793819(cd40lg)
LCM: 
102357754(CD40LG)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Gaur U, Aggarwal BB
  Title
Regulation of proliferation, survival and apoptosis by members of the TNF superfamily.
  Journal
Biochem Pharmacol 66:1403-8 (2003)
Reference
  Authors
Bodmer JL, Schneider P, Tschopp J.
  Title
The molecular architecture of the TNF superfamily.
  Journal
Trends Biochem Sci 27:19-26 (2002)

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