KEGG ORTHOLOGY: K03351

ORTHOLOGY: K03351

Entry

K03351 KO

Name

APC4

Definition

anaphase-promoting complex subunit 4

Pathway

ko04110	Cell cycle
ko04111	Cell cycle - yeast
ko04113	Meiosis - yeast
ko04114	Oocyte meiosis
ko04120	Ubiquitin mediated proteolysis
ko04914	Progesterone-mediated oocyte maturation
ko05166	HTLV-I infection

Module

M00389

APC/C complex

Brite

KEGG Orthology (KO) [BR:ko00001]
Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K03351  APC4; anaphase-promoting complex subunit 4
Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K03351  APC4; anaphase-promoting complex subunit 4
   04111 Cell cycle - yeast
    K03351  APC4; anaphase-promoting complex subunit 4
   04113 Meiosis - yeast
    K03351  APC4; anaphase-promoting complex subunit 4
   04114 Oocyte meiosis
    K03351  APC4; anaphase-promoting complex subunit 4
Organismal Systems
  Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K03351  APC4; anaphase-promoting complex subunit 4
Human Diseases
  Infectious diseases
   05166 HTLV-I infection
    K03351  APC4; anaphase-promoting complex subunit 4
KEGG modules [BR:ko00002]
Structural complex
  Genetic information processing
   Ubiquitin system
    M00389  APC/C complex
     K03351  APC4; anaphase-promoting complex subunit 4
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   APC/C
    Other subunits
     K03351  APC4; anaphase-promoting complex subunit 4
Chromosome [BR:ko03036]
Eukaryotic Type
  Sister chromatid separation proteins
   APC/C complex
    K03351  APC4; anaphase-promoting complex subunit 4

Genes

HSA:	29945(ANAPC4)
PTR:	461149(ANAPC4)
PPS:	100993426(ANAPC4)
GGO:	101142841(ANAPC4) 109024807
PON:	100172595(ANAPC4)
NLE:	100592275(ANAPC4)
MCC:	694006(ANAPC4)
MCF:	101866196(ANAPC4)
CSAB:	103246266(ANAPC4)
RRO:	104662078(ANAPC4)
RBB:	108525947(ANAPC4)
CJC:	100408606(ANAPC4)
SBQ:	101049272(ANAPC4)
MMU:	52206(Anapc4)
RNO:	305420(Anapc4)
CGE:	100767504(Anapc4)
NGI:	103737511(Anapc4)
HGL:	101699443(Anapc4)
CCAN:	109682631(Anapc4)
OCU:	100350229(ANAPC4)
TUP:	102469333(ANAPC4)
CFA:	479123(ANAPC4)
AML:	100480006(ANAPC4)
UMR:	103658379(ANAPC4)
FCA:	101080283(ANAPC4)
PTG:	102957062(ANAPC4)
AJU:	106975106(ANAPC4)
BTA:	514572(ANAPC4)
BOM:	102278163(ANAPC4)
BIU:	109560377(ANAPC4)
PHD:	102343601(ANAPC4)
CHX:	102183223(ANAPC4)
OAS:	101105914(ANAPC4)
SSC:	100518619(ANAPC4)
CFR:	102515278(ANAPC4)
CDK:	105098371(ANAPC4)
BACU:	103005872(ANAPC4)
LVE:	103075604(ANAPC4)
ECB:	100067388(ANAPC4)
EPZ:	103546883(ANAPC4)
EAI:	106840434(ANAPC4)
MYB:	102249169(ANAPC4)
MYD:	102769723(ANAPC4)
HAI:	109382710(ANAPC4)
RSS:	109453835(ANAPC4)
PALE:	102887771(ANAPC4)
LAV:	100656117(ANAPC4)
MDO:	100012855(ANAPC4)
SHR:	100929092(ANAPC4)
OAA:	100083300(ANAPC4)
GGA:	422805(ANAPC4)
MGP:	100540792(ANAPC4)
CJO:	107313933(ANAPC4)
APLA:	101805070(ANAPC4)
ACYG:	106035888(ANAPC4)
TGU:	100231402(ANAPC4)
GFR:	102036004(ANAPC4)
FAB:	101807496(ANAPC4)
PHI:	102111623(ANAPC4)
CCW:	104690697(ANAPC4)
FPG:	101916322(ANAPC4)
FCH:	102056193(ANAPC4)
CLV:	102084273(ANAPC4)
AAM:	106498734(ANAPC4)
ASN:	102374314(ANAPC4)
AMJ:	102571851(ANAPC4)
PSS:	102445946(ANAPC4) 102452227
CMY:	102944376(ANAPC4)
CPIC:	101949863(ANAPC4)
ACS:	100566439(anapc4)
PBI:	103059845(ANAPC4)
GJA:	107115126(ANAPC4)
XLA:	414530(anapc4.L)
XTR:	100216159(anapc4)
NPR:	108794993(ANAPC4)
DRE:	494046(anapc4)
SRX:	107718415 107735811 107755257(anapc4)
SANH:	107665412 107683992
SGH:	107597467 107601943(anapc4)
IPU:	108257709(anapc4)
TRU:	101071757(anapc4)
TNG:	GSTEN00032787G001
LCO:	104919075(anapc4) 109142914
MZE:	101481954(anapc4)
OLA:	101154933(anapc4)
XMA:	102224791(anapc4)
CSEM:	103398076(anapc4)
LCF:	108878899(anapc4)
SASA:	106560255(anapc4)
ELS:	105011814(anapc4)
SFM:	108922811(anapc4)
LCM:	102354298 102365164(ANAPC4)
CMK:	103175832(anapc4)
BFO:	BRAFLDRAFT_124012
CIN:	100186302
SPU:	575488
SKO:	102805627
DME:	Dmel_CG32707(APC4)
DPO:	Dpse_GA17093 Dpse_GA26635
DAN:	Dana_GF19190
DER:	Dere_GG18284
DPE:	Dper_GL12977 Dper_GL23564
DSE:	Dsec_GM13713
DSI:	Dsimw501_GD16927(Dsim_GD16927)
DWI:	Dwil_GK25758
DYA:	Dyak_GE15816
DGR:	Dgri_GH17803
DMO:	Dmoj_GI15143
DVI:	Dvir_GJ19003
MDE:	101897321
AGA:	AgaP_AGAP002345
AAG:	AaeL_AAEL000116
CQU:	CpipJ_CPIJ009644
AME:	409810
BIM:	100740848
BTER:	100649293
SOC:	105200814
AEC:	105143678
ACEP:	105617312
PBAR:	105429711
HST:	105185377
CFO:	105256839
LHU:	105674578 105677997
NVI:	100118948
TCA:	659284
DPA:	109534672 109535593 109537217 109544363 109546119
NVL:	108565719
BMOR:	101742453
DPL:	KGM_216007
PXY:	105385646
API:	100167194
DNX:	107161757
PHU:	Phum_PHUM419840
DPX:	DAPPUDRAFT_53934
ISC:	IscW_ISCW017613
TUT:	107363696
BMY:	Bm1_46355
LOA:	LOAG_05004
HRO:	HELRODRAFT_167167
LGI:	LOTGIDRAFT_232820
CRG:	105338657
OBI:	106884231
LAK:	106168532 106168564
SMM:	Smp_136960
OVI:	T265_07666
NVE:	NEMVE_v1g131737
ADF:	107350486
HMG:	100203849
TAD:	TRIADDRAFT_55371
AQU:	105314126
ATH:	AT4G21530(APC4)
CRB:	CARUB_v10007227mg
EUS:	EUTSA_v10024471mg
BRP:	103859125
BNA:	106358610 106375728
THJ:	104812734
CIT:	102627214
CIC:	CICLE_v10014364mg
TCC:	18596950
GRA:	105777976
GHI:	107925255
EGR:	104428393 104428397 104431802 104435855 104438687 104438708 104442424 104442430 104443306 104444645 104447330 108954015 108959526
GMX:	100527617
PVU:	PHAVU_002G222500g
VRA:	106766757
VAR:	108343835
CCAJ:	109805100
MTR:	MTR_4g090990
CAM:	101507734
ADU:	107480633
AIP:	107627979
LANG:	109339013
FVE:	101308844
PPER:	18780071
PMUM:	103324640
MDM:	103446561 103446562
ZJU:	107423011
CSV:	101220229
CMO:	103501540
RCU:	8289828
JCU:	105649464
POP:	POPTR_0004s03490g(POPTRDRAFT_817758)
VVI:	100255109 100854764
SLY:	101255653
SPEN:	107011184
SOT:	102591780
CANN:	107859458
NTA:	107771175 107831050
INI:	109159078
SIND:	105167928
BVG:	104909119
NNU:	104599129
OSA:	4330947(OJ1316_E06.7)
OBR:	102716293
BDI:	100825517
ATS:	F775_02751
SBI:	8082701
ZMA:	100304372
SITA:	101758832
PDA:	103699778 103718156
EGU:	105040099
MUS:	104000087
ATR:	18435506
SMO:	SELMODRAFT_89017
PPP:	PHYPADRAFT_168296
MIS:	MICPUN_58493
MPP:	MICPUCDRAFT_56629
CSL:	COCSUDRAFT_46664
CVR:	CHLNCDRAFT_142451
APRO:	F751_3344
SCE:	YDR118W(APC4)
AGO:	AGOS_AGR078C
ERC:	Ecym_4300
KLA:	KLLA0F19316g
LTH:	KLTH0G13508g
VPO:	Kpol_392p1
ZRO:	ZYRO0C01474g
CGR:	CAGL0B01859g
NCS:	NCAS_0B03790(NCAS0B03790)
NDI:	NDAI_0J01270(NDAI0J01270)
TPF:	TPHA_0J00790(TPHA0J00790)
TBL:	TBLA_0C04570(TBLA0C04570)
TDL:	TDEL_0F03970(TDEL0F03970)
KAF:	KAFR_0B05460(KAFR0B05460)
PPA:	PAS_chr3_0477
DHA:	DEHA2B08316g
PIC:	PICST_50092
PGU:	PGUG_02166
SPAA:	SPAPADRAFT_61013
LEL:	LELG_03990
CAL:	CAALFM_C500060CA(CaO19.5692)
CTP:	CTRG_05228
COT:	CORT_0B02610
CDU:	CD36_50100
YLI:	YALI0D12705g
CLU:	CLUG_00726
NCR:	NCU00494
NTE:	NEUTE1DRAFT122482(NEUTE1DRAFT_122482)
SMP:	SMAC_01925
PAN:	PODANSg5067
TTT:	THITE_2118487
MTM:	MYCTH_2304760
CTHR:	CTHT_0026320
MGR:	MGG_05678
TMN:	UCRPA7_6359
FGR:	FGSG_05437
FPU:	FPSE_03570
FVR:	FVEG_07090
FOX:	FOXG_09461
NHE:	NECHADRAFT_101327
TRE:	TRIREDRAFT_54244
MAW:	MAC_08351
MAJ:	MAA_03573
CMT:	CCM_07395
VAL:	VDBG_08709
VDA:	VDAG_06370
CFJ:	CFIO01_03342
ELA:	UCREL1_8397
PFY:	PFICI_12965
SSL:	SS1G_07126
BFU:	BC1G_10196
MBE:	MBM_02156
PSCO:	LY89DRAFT_672835
GLZ:	GLAREA_07599
ANI:	AN0905.2
AFM:	AFUA_1G15710
AOR:	AOR_1_1976174(AO090005001135)
ANG:	ANI_1_1904014(An01g14050)
AFV:	AFLA_083760
ACT:	ACLA_019660
NFI:	NFIA_009620
PCS:	Pc06g01880
PDP:	PDIP_65430
CIM:	CIMG_03115
CPW:	CPC735_010330
PBL:	PAAG_05339
PBN:	PADG_06682
URE:	UREG_02843
ABE:	ARB_02145
TVE:	TRV_01494
AJE:	HCAG_02275
PNO:	SNOG_01935
PTE:	PTT_17150
BZE:	COCCADRAFT_312
BOR:	COCMIDRAFT_92220
BCOM:	BAUCODRAFT_281096
SPO:	SPAC19G12.01c(cut20)
DSQ:	DICSQDRAFT_176475
SHS:	STEHIDRAFT_117482
PSQ:	PUNSTDRAFT_59241
FME:	FOMMEDRAFT_167218
MRR:	Moror_13255
CCI:	CC1G_13643
ABP:	AGABI1DRAFT124189(AGABI1DRAFT_124189)
CPUT:	CONPUDRAFT_134079
SLA:	SERLADRAFT_454537
WSE:	WALSEDRAFT_60682
WIC:	J056_003973
SRE:	PTSG_02141
DDI:	DDB_G0285223(anapc4)
DPP:	DICPUDRAFT_100160
DFA:	DFA_01295(anapc4)
ACAN:	ACA1_073040
TET:	TTHERM_00149850
AAF:	AURANDRAFT_72273
PIF:	PITG_01169
PSOJ:	PHYSODRAFT_300421
SPAR:	SPRG_11649
EHX:	EMIHUDRAFT_467828
GTT:	GUITHDRAFT_134093

» show all

Reference

PMID:18485873

Authors

Jin L, Williamson A, Banerjee S, Philipp I, Rape M

Title

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex.

Journal

Cell 133:653-65 (2008)
DOI:10.1016/j.cell.2008.04.012

Sequence

[hsa:29945]

Reference

PMID:16763193

Authors

Acquaviva C, Pines J.

Title

The anaphase-promoting complex/cyclosome: APC/C.

Journal

J Cell Sci 119:2401-4 (2006)
DOI:10.1242/jcs.02937

Sequence

[dme:Dmel_CG32707]

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (15)   
   KEGG PATHWAY (14)   
   KEGG MODULE (1)   
Gene (801)   
   KEGG GENES (343)   
   KEGG MGENES (314)   
   RefGene (43)   
   EGENES (80)   
   OC (21)   
Protein sequence (185)   
   UniProt (178)   
   SWISS-PROT (7)   
Literature (2)   
   PubMed (2)   
All databases (1007)   

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