KEGG   ORTHOLOGY: K03873Help
Entry
K03873                      KO                                     

Name
TCEB2
Definition
transcription elongation factor B, polypeptide 2
Pathway
HIF-1 signaling pathway
Ubiquitin mediated proteolysis
Pathways in cancer
Renal cell carcinoma
Module
M00383  
ECV complex
M00388  
ECS complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K03873  TCEB2; transcription elongation factor B, polypeptide 2
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    K03873  TCEB2; transcription elongation factor B, polypeptide 2
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K03873  TCEB2; transcription elongation factor B, polypeptide 2
   05211 Renal cell carcinoma
    K03873  TCEB2; transcription elongation factor B, polypeptide 2
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00383  ECV complex
     K03873  TCEB2; transcription elongation factor B, polypeptide 2
    M00388  ECS complex
     K03873  TCEB2; transcription elongation factor B, polypeptide 2
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  multi subunit Ring-finger type E3
   ECV complex
    adoptor protein
     K03873  TCEB2; transcription elongation factor B, polypeptide 2
   ECS complex
    adoptor protein
     K03873  TCEB2; transcription elongation factor B, polypeptide 2
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    Other NER factors
     K03873  TCEB2; transcription elongation factor B, polypeptide 2
BRITE hierarchy
Genes
HSA: 
6923(TCEB2)
PTR: 
750134(TCEB2)
PPS: 
GGO: 
101148160(TCEB2)
PON: 
100456083(TCEB2)
NLE: 
MCC: 
715218(TCEB2)
MCF: 
CJC: 
MMU: 
67673(Tceb2)
RNO: 
81807(Tceb2)
CGE: 
HGL: 
TUP: 
CFA: 
479873(TCEB2)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
617277(TCEB2)
BOM: 
PHD: 
102340763(TCEB2)
CHX: 
102175351(TCEB2)
OAS: 
SSC: 
100519651(TCEB2)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
102256914(TCEB2)
MYD: 
102765630(TCEB2)
PALE: 
102895498(TCEB2)
MDO: 
SHR: 
OAA: 
100090222(TCEB2)
PHI: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
100562302(tceb2)
PBI: 
XLA: 
380106(tceb2)
XTR: 
394559(tceb2)
DRE: 
192341(tceb2)
TRU: 
MZE: 
OLA: 
XMA: 
CMK: 
103171651(tceb2)
BFO: 
CIN: 
SPU: 
DME: 
Dmel_CG4204(Elongin-B)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
551511(Elongin-B)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG13236(Cbr-elb-1)
BMY: 
LOA: 
HRO: 
LGI: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ALY: 
MDM: 
CSV: 
CMO: 
CVR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Mahrour N, Redwine WB, Florens L, Swanson SK, Martin-Brown S, Bradford WD, Staehling-Hampton K, Washburn MP, Conaway RC, Conaway JW
  Title
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.
  Journal
J Biol Chem 283:8005-13 (2008)
  Sequence
[hsa:6923]
Reference
PMID:7638163
  Authors
Garrett KP, Aso T, Bradsher JN, Foundling SI, Lane WS, Conaway RC, Conaway JW
  Title
Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog.
  Journal
Proc Natl Acad Sci U S A 92:7172-6 (1995)
  Sequence
[hsa:6923] [rno:81807]

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