KEGG   ORTHOLOGY: K03935Help
Entry
K03935                      KO                                     

Name
NDUFS2
Definition
NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
Pathway
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko04714  Thermogenesis
ko04723  Retrograde endocannabinoid signaling
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05010  Alzheimer's disease
ko05012  Parkinson's disease
ko05016  Huntington's disease
Module
M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Disease
H00473  Mitochondrial respiratory chain deficiencies (MRCD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Energy metabolism
   00190 Oxidative phosphorylation
    K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
 Organismal Systems
  Nervous system
   04723 Retrograde endocannabinoid signaling
    K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
  Environmental adaptation
   04714 Thermogenesis
    K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
   05012 Parkinson's disease
    K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
   05016 Huntington's disease
    K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
KEGG modules [BR:ko00002]
 Structural complex
  Energy metabolism
   ATP synthesis
    M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
     K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.5  With a quinone or similar compound as acceptor
    1.6.5.3  NADH:ubiquinone reductase (H+-translocating)
     K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
   1.6.99  With unknown physiological acceptors
    1.6.99.3  NADH dehydrogenase
     K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2
BRITE hierarchy
Other DBs
RN: R11945
GO: 0008137 0003954
TC: 3.D.1.6
Genes
HSA: 4720(NDUFS2)
PTR: 747334(NDUFS2)
PPS: 100978992(NDUFS2)
PON: 100461547(NDUFS2)
NLE: 100603263(NDUFS2)
MCC: 719935(NDUFS2)
MCF: 101925833(NDUFS2) 102117050
CSAB: 103223688(NDUFS2)
RRO: 104664715 104665340(NDUFS2)
RBB: 108521164(NDUFS2) 108522021 108525091
CJC: 100415319(NDUFS2)
SBQ: 101049213(NDUFS2)
MMU: 226646(Ndufs2)
RNO: 289218(Ndufs2)
CGE: 100768067(Ndufs2)
NGI: 103745951(Ndufs2)
HGL: 101701670(Ndufs2)
CCAN: 109693207(Ndufs2)
OCU: 100352168(NDUFS2)
TUP: 102502777(NDUFS2)
CFA: 478981(NDUFS2)
AML: 100481212(NDUFS2)
UMR: 103672016(NDUFS2)
ORO: 101367772(NDUFS2)
FCA: 101088298(NDUFS2)
PTG: 102956606(NDUFS2)
AJU: 106978535(NDUFS2)
BTA: 327697(NDUFS2)
BOM: 102274147(NDUFS2)
BIU: 109578296(NDUFS2)
PHD: 102344873(NDUFS2)
CHX: 102190747(NDUFS2)
OAS: 101104108(NDUFS2)
SSC: 100156075(NDUFS2)
CFR: 102524292(NDUFS2)
CDK: 105100106(NDUFS2)
BACU: 103013023(NDUFS2)
LVE: 103084921(NDUFS2)
OOR: 101277400(NDUFS2)
ECB: 100066089(NDUFS2)
EPZ: 103559989(NDUFS2)
EAI: 106827589(NDUFS2)
MYB: 102262139(NDUFS2)
MYD: 102774289(NDUFS2)
HAI: 109376934(NDUFS2)
RSS: 109435223(NDUFS2)
PALE: 102896927(NDUFS2)
LAV: 100654713(NDUFS2)
TMU: 101348326
MDO: 100028959(NDUFS2)
SHR: 100922998(NDUFS2)
GGA: 100857596(NDUFS2)
MGP: 104915859(NDUFS2)
CJO: 107307779(NDUFS2)
APLA: 101793923(NDUFS2)
GFR: 102035718(NDUFS2)
FAB: 101811118(NDUFS2)
PHI: 102104978(NDUFS2) 106629022
FPG: 101924701(NDUFS2)
FCH: 102058442(NDUFS2)
CLV: 102093867(NDUFS2)
EGZ: 104124796(NDUFS2)
AAM: 106500504(NDUFS2)
ASN: 102368417(NDUFS2)
AMJ: 102572812(NDUFS2)
PSS: 102449264(NDUFS2)
CMY: 102936535(NDUFS2)
CPIC: 101952582(NDUFS2)
ACS: 100565070(ndufs2)
PVT: 110081004(NDUFS2)
PBI: 103061099(NDUFS2)
GJA: 107108402(NDUFS2)
XLA: 108699611 734895(ndufs2.L)
XTR: 394993(ndufs2)
NPR: 108802054(NDUFS2)
DRE: 553672(ndufs2) 641476(zgc:123301)
SRX: 107731872 107738057
SANH: 107679282 107683510
SGH: 107558431 107597916
IPU: 108267761(ndufs2)
AMEX: 103041339(ndufs2)
TRU: 101073744(ndufs2)
TNG: GSTEN00006157G001
LCO: 104924054(ndufs2)
NCC: 104945964(ndufs2)
MZE: 101467150(ndufs2)
OLA: 101168577(ndufs2)
XMA: 102222086(ndufs2)
PRET: 103480169(ndufs2)
NFU: 107384776(ndufs2)
CSEM: 103391268(ndufs2)
LCF: 108882028(ndufs2)
HCQ: 109511900(ndufs2)
BPEC: 110171241(ndufs2)
SASA: 106608746(ndufs2)
ELS: 105030963(ndufs2)
SFM: 108926077(ndufs2)
LCM: 102349663(NDUFS2)
CMK: 103175779(ndufs2)
BFO: BRAFLDRAFT_114745
CIN: 100176138
SPU: 581848 590673
APLC: 110988892
SKO: 100374503
DME: Dmel_CG11913(ND-49L) Dmel_CG1970(ND-49)
DPO: Dpse_GA11278 Dpse_GA25154
DAN: Dana_GF16933 Dana_GF19015
DER: Dere_GG11402 Dere_GG16443
DPE: Dper_GL12099 Dper_GL18172
DSE: Dsec_GM17844 Dsec_GM26777
DSI: Dsimw501_GD21215(Dsim_GD21215) Dsimw501_GD29195(Dsim_GD29195)
DWI: Dwil_GK11092 Dwil_GK13585
DYA: Dyak_GE14510 Dyak_GE23599
DGR: Dgri_GH18233 Dgri_GH23924
DMO: Dmoj_GI10189 Dmoj_GI14091
DVI: Dvir_GJ13840 Dvir_GJ23477
MDE: 101901303
AGA: AgaP_AGAP000794 AgaP_AGAP006891
AAG: 5574746
CQU: CpipJ_CPIJ011528
AME: 413891(Ndufs2)
BIM: 100740718
BTER: 100645888
SOC: 105193097
AEC: 105146000
ACEP: 105623581
PBAR: 105431009
HST: 105181499
CFO: 105249337
LHU: 105678696
PGC: 109860224
NVI: 100114733(Ndufs2) 100115931
TCA: 660813 661641(nuoD)
DPA: 109535059 109539384 109542126
NVL: 108561146 108565898
BMOR: 101739282 732900
DPL: KGM_203997 KGM_204928
PMAC: 106707293 106708250 106719953
PRAP: 111000356 111000710
PXY: 105385887 105391108 105393269
API: 100160406
DNX: 107170896
PHU: Phum_PHUM399580
ZNE: 110828970
FCD: 110858686
DPX: DAPPUDRAFT_305286 DAPPUDRAFT_307186 DAPPUDRAFT_66167 DAPPUDRAFT_67608
ISC: IscW_ISCW017643
TUT: 107364096
CEL: CELE_K09A9.5(gas-1) CELE_T26A5.3(nduf-2.2)
CBR: CBG07730(Cbr-gas-1) CBG19683(Cbr-tag-99)
NAI: NECAME_02814
BMY: Bm1_25145 Bm1_38090
LOA: LOAG_01369 LOAG_05466
HRO: HELRODRAFT_75061
LGI: LOTGIDRAFT_213061
CRG: 105319696
MYI: 110444135 110450749
OBI: 106867881
LAK: 106176336
SMM: Smp_127340
SHX: MS3_06660
OVI: T265_09475
NVE: NEMVE_v1g110807
EPA: 110240988
ADF: 107330376 107352471
HMG: 100214060 101236667
TAD: TRIADDRAFT_49563
AQU: 100641631
ATH: ArthMp043(nad7)
EUS: EUTSA_v10028891mg
BNA: 4237893(nad7)
CPAP: 7441442(nad7)
GRA: 27429579(nad7)
GHI: 24679489(nad7)
GMX: 15308597(nad7)
VAR: 15382776(nad7)
MTR: A0S16_gp16(nad7)
MDM: 13630185(nad7)
ZJU: 107418627 27215272(nad7)
CSV: 11123862(nad7)
RCU: 10221393(nad7)
VVI: 109122063 7498533(nad7)
CANN: 19988957(nad7)
NTA: 3205185(nad7)
NSY: 27214887(nad7)
INI: 29082051(nad7)
HAN: 110870575
LSV: 111880662
DCR: 12598542(nad7)
BVG: 809505(BevupMp083) 809509(nad7)
SOE: 33876590(nad7)
NNU: 28482670(nad7)
OSA: 6450198(nad7)
ATS: 109785080
SBI: 4306020(nad7)
ZMA: 109942203
PDA: 11542578(nad7)
CRE: CHLREDRAFT_185013(NUO7)
VCN: VOLCADRAFT_84552(nuo7)
MNG: MNEG_9543
OTA: OstapMp15(nad7)
BPG: BathyMg00160(nad7)
MIS: MicpuN_mit76(nad7)
CSL: CospCoM_p19(nad7)
CVR: OJ20_p08(nad7)
APRO: ChprMp033(nad7)
CME: CYME_CMJ211C
GSL: Gasu_27220
CCP: CHC_T00008467001 CHC_T00008797001
PPA: PAS_chr3_0808
DHA: DEHA2F10120g
PIC: PICST_68160(NUC1)
PGU: PGUG_04269
SPAA: SPAPADRAFT_63571
LEL: LELG_05138
CAL: CAALFM_C701900WA(NUC2)
CTP: CTRG_05173
COT: CORT_0G03580
CDU: CD36_71710
CTEN: CANTEDRAFT_113697
YLI: YALI0F17248g
CLU: CLUG_01453
CLUS: A9F13_06g02673
CAUR: QG37_01789
SLB: AWJ20_4375
NCR: NCU02534(nuo49)
NTE: NEUTE1DRAFT119090(NEUTE1DRAFT_119090)
SMP: SMAC_05824
PAN: PODANSg10140
TTT: THITE_2114055
MTM: MYCTH_2295737
CTHR: CTHT_0057080
MGR: MGG_09285
TMN: UCRPA7_1236
FGR: FGSG_00376
FPU: FPSE_00037
FVR: FVEG_00831
FOX: FOXG_00680
NHE: NECHADRAFT_90188
TRE: TRIREDRAFT_76159
MAW: MAC_08805
MAJ: MAA_04320
CMT: CCM_02263
PLJ: VFPFJ_05206
VAL: VDBG_04705
VDA: VDAG_04247
CFJ: CFIO01_04949
ELA: UCREL1_5440
PFY: PFICI_01104
SSL: SS1G_02958
BFU: BC1G_02234
MBE: MBM_02445
PSCO: LY89DRAFT_606697 LY89DRAFT_709428
GLZ: GLAREA_00802
ANI: AN2414.2
AFM: AFUA_2G13710
AOR: AO090026000229
ANG: ANI_1_754024(An02g05470)
AFV: AFLA_137010
ACT: ACLA_073930
NFI: NFIA_088890
PCS: Pc12g12260
PDP: PDIP_78810
CIM: CIMG_04633
CPW: CPC735_071740
PBL: PAAG_05735
PBN: PADG_07654
URE: UREG_01832
ABE: ARB_04412
TVE: TRV_06252
AJE: HCAG_04623
PNO: SNOG_04659
PTE: PTT_10543
BZE: COCCADRAFT_5915
BSC: COCSADRAFT_182335
BOR: COCMIDRAFT_31819
AALT: CC77DRAFT_1024482
ZTR: MYCGRDRAFT_104474
PFJ: MYCFIDRAFT_167272
BCOM: BAUCODRAFT_123871
NPA: UCRNP2_3658
TML: GSTUM_00003603001
CNE: CNH02730
CNB: CNBL2770
CGI: CGB_L3400C
TMS: TREMEDRAFT_45745
TVS: TRAVEDRAFT_67970
DSQ: DICSQDRAFT_131369
PCO: PHACADRAFT_248119
SHS: STEHIDRAFT_89393
HIR: HETIRDRAFT_456657
PSQ: PUNSTDRAFT_96133
ADL: AURDEDRAFT_179456
FME: FOMMEDRAFT_128898
GTR: GLOTRDRAFT_30731
LBC: LACBIDRAFT_186248 LACBIDRAFT_303351 LACBIDRAFT_310215 LACBIDRAFT_330759
MRR: Moror_9972
CCI: CC1G_00725
SCM: SCHCODRAFT_237320 SCHCODRAFT_83235
ABP: AGABI1DRAFT110869(NdufS2)
ABV: AGABI2DRAFT189224(AGABI2DRAFT_189224)
CPUT: CONPUDRAFT_116646
SLA: SERLADRAFT_377171(NdufS2)
WSE: WALSEDRAFT_33711
WIC: J056_000389
UMA: UMAG_11162
PFP: PFL1_02781
MGL: MGL_4072
PGR: PGTG_03025
MLR: MELLADRAFT_33293
SRE: PTSG_10552
DDI: DidioMp18(nad7)
DFA: Difao_mp24(nad7)
TET: TepyoMp12(nad7)
PSOJ: PhsooMp18(nad7)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9647766
  Authors
Loeffen J, van den Heuvel L, Smeets R, Triepels R, Sengers R, Trijbels F, Smeitink J
  Title
cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.
  Journal
Biochem Biophys Res Commun 247:751-8 (1998)
DOI:10.1006/bbrc.1998.8882
  Sequence
[hsa:4720]

  All links  
Ontology (7)   
   KEGG BRITE (4)   
   GO (2)   
   TC (1)   
Pathway (17)   
   KEGG PATHWAY (16)   
   KEGG MODULE (1)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (10052)   
   KEGG GENES (368)   
   KEGG MGENES (1732)   
   RefGene (7882)   
   EGENES (49)   
   OC (21)   
Protein sequence (252)   
   UniProt (243)   
   SWISS-PROT (9)   
Literature (1)   
   PubMed (1)   
All databases (10334)   

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