KEGG ORTHOLOGY: K03937

ORTHOLOGY: K03937

Entry

K03937 KO

Name

NDUFS4

Definition

NADH dehydrogenase (ubiquinone) Fe-S protein 4 [EC:1.6.5.3 1.6.99.3]

Pathway

ko00190	Oxidative phosphorylation
ko05010	Alzheimer's disease
ko05012	Parkinson's disease
ko05016	Huntington's disease

Module

M00143

NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria

Disease

H00473

Mitochondrial respiratory chain deficiencies (MRCD)

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Energy metabolism
   00190 Oxidative phosphorylation
    K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
   05012 Parkinson's disease
    K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
   05016 Huntington's disease
    K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
KEGG pathway modules [BR:ko00002]
Structural complex
  Energy metabolism
   ATP synthesis
    M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
     K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.5  With a quinone or similar compound as acceptor
    1.6.5.3  NADH:ubiquinone reductase (H+-translocating)
     K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
   1.6.99  With other acceptors
    1.6.99.3  NADH dehydrogenase
     K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4

Other DBs

GO:

0008137 0003954

Genes

HSA:	4724(NDUFS4)
PTR:	461878(NDUFS4)
PPS:	100980708(NDUFS4)
GGO:	101125075(NDUFS4)
PON:	100172316(NDUFS4)
MCC:	704137(NDUFS4)
MMU:	17993(Ndufs4)
RNO:	499529(Ndufs4)
CFA:	479335(NDUFS4)
AML:	100467769
FCA:	101089240(NDUFS4)
BTA:	327680(NDUFS4)
SSC:	100516161
ECB:	100063168
MDO:	100031559
SHR:	100930936(NDUFS4)
OAA:	100075551
GGA:	374122(NDUFS4)
TGU:	100190761(NDUFS4)
ACS:	100558063
XLA:	447172(ndufs4)
XTR:	100125122(ndufs4)
DRE:	573689(ndufs4)
TRU:	101065318
CIN:	100182853
SPU:	100888952
DME:	Dmel_CG12203
DPO:	Dpse_GA11474
DAN:	Dana_GF20193
DER:	Dere_GG19227
DPE:	Dper_GL13999 Dper_GL14531
DSE:	Dsec_GM22960
DSI:	Dsim_GD17444
DWI:	Dwil_GK25430
DYA:	Dyak_GE15845
DGR:	Dgri_GH17652
DMO:	Dmoj_GI16090
DVI:	Dvir_GJ15739
AGA:	AgaP_AGAP007082
AAG:	AaeL_AAEL013744
CQU:	CpipJ_CPIJ008770
AME:	727599(Ndufs4)
NVI:	100116901(Ndufs4)
TCA:	664573(Ndufs4)
API:	100164295(Ndufs4)
PHU:	Phum_PHUM387800
ISC:	IscW_ISCW014628
CEL:	CELE_ZK973.10(lpd-5)
CBR:	CBG23930(Cbr-lpd-5)
BMY:	Bm1_55425
TSP:	Tsp_03499
SMM:	Smp_018020
NVE:	NEMVE_v1g236104
HMG:	100212472
TAD:	TRIADDRAFT_22290
AQU:	100634278
ATH:	AT5G67590(FRO1)
ALY:	ARALYDRAFT_358798
GMX:	100526873
MTR:	MTR_4g097160
CSV:	101203147 101210439 101227046
RCU:	RCOM_0580980
POP:	POPTR_409930 POPTR_820136
VVI:	100245052 100250742
OSA:	4343746
DOSA:	Os07t0585800-01(Os07g0585800)
BDI:	100833859
SBI:	SORBI_02g037780(SORBIDRAFT_02g037780)
ZMA:	100193844 100281028(pco104752)
SMO:	SELMODRAFT_143005 SELMODRAFT_18036
PPP:	PHYPADRAFT_18919 PHYPADRAFT_48732
CRE:	CHLREDRAFT_184606(NUOS4)
VCN:	VOLCADRAFT_77953(nuoS4)
CME:	CMO080C
PPA:	PAS_chr2-2_0366
DHA:	DEHA2F20812g
PIC:	PICST_62206(NUO21.2)
PGU:	PGUG_00320
LEL:	LELG_01368
CAL:	CaO19.10800 CaO19.3290
CTP:	CTRG_04402
CDU:	CD36_00960
COT:	CORT_0B11080
YLI:	YALI0B14861g
CLU:	CLUG_03938
NCR:	NCU05221
SMP:	SMAC_07180
PAN:	PODANSg3777
TTT:	THITE_60812
MTM:	MYCTH_73070
MGR:	MGG_04136
FGR:	FG02474.1
NHE:	NECHADRAFT_70137
SSL:	SS1G_13868
BFU:	BC1G_13852
ANI:	AN7497.2
NFI:	NFIA_082220
AFM:	AFUA_2G05500
AOR:	AOR_1_1192164(AO090001000661)
ANG:	ANI_1_1174094(An11g09390)
AFV:	AFLA_129650
ACT:	ACLA_089200
PCS:	Pc22g09110
CIM:	CIMG_00752
CPW:	CPC735_055420
PBL:	PAAG_02266
ABE:	ARB_03885
TVE:	TRV_06626
AJE:	HCAG_00972
PNO:	SNOG_08966
PTE:	PTT_08515
ZTR:	MYCGRDRAFT_87601
TML:	GSTUM_00002958001
CNE:	CNM01810
CNB:	CNBM1690
CGI:	CGB_M2440C
LBC:	LACBIDRAFT_148506
MPR:	MPER_11281
CCI:	CC1G_07164
SCM:	SCHCODRAFT_53560
UMA:	UM00512.1
MGL:	MGL_1562
PGR:	PGTG_10558
MBR:	MONBRDRAFT_14804
NGR:	NAEGRDRAFT_79997
TET:	TTHERM_00526930
PTM:	GSPATT00014427001

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Pathway (95)   
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   KEGG GENES (136)   
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   KEGG EGENES (199)   
   KEGG MGENES (28)   
Protein sequence (113)   
   UniProt (113)   
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