KEGG   ORTHOLOGY: K03982Help
Entry
K03982                      KO                                     

Name
SERPINE1, PAI1
Definition
plasminogen activator inhibitor-1
Pathway
HIF-1 signaling pathway
p53 signaling pathway
Hippo signaling pathway
Complement and coagulation cascades
Chagas disease (American trypanosomiasis)
Disease
H00223  
Inherited thrombophilia
H01106  
Plasminogen activator inhibitor type 1 (PAI-1) deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04390 Hippo signaling pathway
    K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
   04066 HIF-1 signaling pathway
    K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
 Cellular Processes
  Cell growth and death
   04115 p53 signaling pathway
    K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
 Organismal Systems
  Immune system
   04610 Complement and coagulation cascades
    K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
 Human Diseases
  Infectious diseases
   05142 Chagas disease (American trypanosomiasis)
    K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
Heparan sulfate/heparin binding proteins [BR:ko00536]
 Coagulation and fibrinolysis
  K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
BRITE hierarchy
Genes
HSA: 
5054(SERPINE1)
PTR: 
472467(SERPINE1)
PPS: 
100973457(SERPINE1)
GGO: 
101149162(SERPINE1)
PON: 
100435876(SERPINE1)
MCC: 
713883(SERPINE1)
MCF: 
102147003(SERPINE1)
MMU: 
18787(Serpine1)
RNO: 
24617(Serpine1)
CGE: 
HGL: 
101703903(Serpine1)
TUP: 
102478468(SERPINE1)
CFA: 
403476(SERPINE1)
AML: 
FCA: 
100127105(SERPINE1)
BTA: 
281375(SERPINE1)
BOM: 
102275884(SERPINE1)
PHD: 
102322571(SERPINE1)
CHX: 
102169375(SERPINE1)
SSC: 
396945(SERPINE1)
CFR: 
102505188(SERPINE1)
ECB: 
100033931(PAI-1)
MYB: 
102262847(SERPINE1)
MDO: 
SHR: 
100922915(SERPINE1)
OAA: 
PSS: 
102443480(SERPINE1)
ACS: 
XLA: 
779433(serpine1)
XTR: 
100127732(serpine1)
DRE: 
100136840(serpine1)
TRU: 
MZE: 
OLA: 
100529196(serpine1)
XMA: 
LCM: 
102360184(SERPINE1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Vial D, McKeown-Longo PJ
  Title
PAI1 stimulates assembly of the fibronectin matrix in osteosarcoma cells through  crosstalk between the alphavbeta5 and alpha5beta1 integrins.
  Journal
J Cell Sci 121:1661-70 (2008)

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