KEGG   ORTHOLOGY: K03990Help
Entry
K03990                      KO                                     

Name
C3
Definition
complement component 3
Pathway
Phagosome
Complement and coagulation cascades
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Staphylococcus aureus infection
Tuberculosis
Herpes simplex infection
Viral carcinogenesis
Systemic lupus erythematosus
Disease
H00102  
Classic complement pathway component defects
H00821  
Macular degeneration
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K03990  C3; complement component 3
 Organismal Systems
  Immune system
   04610 Complement and coagulation cascades
    K03990  C3; complement component 3
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K03990  C3; complement component 3
  Immune diseases
   05322 Systemic lupus erythematosus
    K03990  C3; complement component 3
  Infectious diseases
   05133 Pertussis
    K03990  C3; complement component 3
   05134 Legionellosis
    K03990  C3; complement component 3
   05150 Staphylococcus aureus infection
    K03990  C3; complement component 3
   05152 Tuberculosis
    K03990  C3; complement component 3
   05168 Herpes simplex infection
    K03990  C3; complement component 3
   05140 Leishmaniasis
    K03990  C3; complement component 3
   05142 Chagas disease (American trypanosomiasis)
    K03990  C3; complement component 3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   K03990  C3; complement component 3
Cell adhesion molecules and their ligands [BR:ko04516]
 2. Integrin Family
  Beta2 integrins
   CR3, Mac-1
    ITGB2; integrin beta 2
     K03990 C3; complement component 3
   p150/95
    ITGB2; integrin beta 2
     K03990 C3; complement component 3
BRITE hierarchy
Genes
HSA: 
718(C3)
PTR: 
455644(C3)
PPS: 
GGO: 
PON: 
MCC: 
703613(C3)
MCF: 
MMU: 
12266(C3)
RNO: 
24232(C3)
CGE: 
HGL: 
TUP: 
CFA: 
476728(C3)
AML: 
FCA: 
BTA: 
280677(C3)
BOM: 
PHD: 
CHX: 
SSC: 
397072(C3)
CFR: 
ECB: 
MYB: 
MDO: 
SHR: 
OAA: 
GGA: 
396370(C3)
MGP: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
ACS: 
XTR: 
DRE: 
30491(c3b) 321046(c3a) 565074(c3c)
TRU: 
MZE: 
OLA: 
100125801(c3-1) 100125802(c3-2)
XMA: 
LCM: 
CIN: 
445694(c3-1)
SPU: 
373284(c3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Sim RB, Tsiftsoglou SA
  Title
Proteases of the complement system.
  Journal
Biochem Soc Trans 32:21-7 (2004)

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