KEGG   ORTHOLOGY: K03990Help
Entry
K03990                      KO                                     

Name
C3
Definition
complement component 3
Pathway
ko04145  Phagosome
ko04610  Complement and coagulation cascades
ko05133  Pertussis
ko05134  Legionellosis
ko05140  Leishmaniasis
ko05142  Chagas disease (American trypanosomiasis)
ko05150  Staphylococcus aureus infection
ko05152  Tuberculosis
ko05167  Kaposi's sarcoma-associated herpesvirus infection
ko05168  Herpes simplex infection
ko05203  Viral carcinogenesis
ko05322  Systemic lupus erythematosus
Disease
H00102  Classic complement pathway component defects
H00821  Age-related macular degeneration
H01434  Atypical hemolytic uremic syndrome (aHUS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K03990  C3; complement component 3
 Organismal Systems
  Immune system
   04610 Complement and coagulation cascades
    K03990  C3; complement component 3
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K03990  C3; complement component 3
  Immune diseases
   05322 Systemic lupus erythematosus
    K03990  C3; complement component 3
  Infectious diseases
   05133 Pertussis
    K03990  C3; complement component 3
   05134 Legionellosis
    K03990  C3; complement component 3
   05150 Staphylococcus aureus infection
    K03990  C3; complement component 3
   05152 Tuberculosis
    K03990  C3; complement component 3
   05168 Herpes simplex infection
    K03990  C3; complement component 3
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K03990  C3; complement component 3
   05140 Leishmaniasis
    K03990  C3; complement component 3
   05142 Chagas disease (American trypanosomiasis)
    K03990  C3; complement component 3
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Opsonins
    K03990  C3; complement component 3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   K03990  C3; complement component 3
BRITE hierarchy
Genes
HSA: 718(C3)
PTR: 455644(C3)
PPS: 100982432(C3)
GGO: 101139062(C3)
PON: 100446798(C3)
NLE: 100598784(C3)
MCC: 703613(C3)
MCF: 102131458(C3)
CSAB: 103234342(C3)
RRO: 104665361(C3)
RBB: 108534593(C3)
CJC: 100400501(C3)
SBQ: 101044671(C3)
MMU: 12266(C3)
RNO: 24232(C3)
CGE: 100763958(C3)
NGI: 103737182(C3)
HGL: 101726247(C3)
CCAN: 109694300(C3) 109698715
OCU: 100009121(C3)
TUP: 102487294(C3)
CFA: 476728(C3)
AML: 100472549(C3)
UMR: 103681871(C3)
ORO: 101385252(C3)
BTA: 280677(C3)
BOM: 102270836(C3)
BIU: 109561686(C3)
CHX: 100860826(C3)
SSC: 397072(C3)
CFR: 102512172(C3)
CDK: 105104550(C3)
BACU: 103011779(C3)
LVE: 103083690(C3)
OOR: 101281425(C3)
RSS: 109434093(C3)
PALE: 102882350(C3)
TMU: 101350977
MDO: 100020034(C3)
OAA: 100074341(C3)
GGA: 396370(C3)
MGP: 100551026(C3)
APLA: 101793615(C3)
ACYG: 106049436(C3)
GFR: 102043273
FAB: 101805832
PHI: 102102912(C3)
PMAJ: 107199229
FPG: 101923177(C3)
FCH: 102047045(C3)
CLV: 102087426(C3)
EGZ: 104129973(C3)
DRE: 30491(c3a.2) 321046(c3a.1) 494039(c3a.6) 565074(c3a.3)
CMK: 103191243(c3)
CIN: 445694(c3-1)
SPU: 373284(c3)
TUT: 107359770
CRG: 105333243
MYI: 110467112
EPA: 110253638
ADF: 107332922
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2579379
  Authors
de Bruijn MH, Fey GH
  Title
Human complement component C3: cDNA coding sequence and derived primary structure.
  Journal
Proc Natl Acad Sci U S A 82:708-12 (1985)
DOI:10.1073/pnas.82.3.708
  Sequence
[hsa:718]
Reference
  Authors
Murray I, Kohl J, Cianflone K
  Title
Acylation-stimulating protein (ASP): structure-function determinants of cell surface binding and triacylglycerol synthetic activity.
  Journal
Biochem J 342 ( Pt 1):41-8 (1999)
DOI:10.1042/bj3420041
  Sequence
[hsa:718]

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