KEGG ORTHOLOGY: K04146

ORTHOLOGY: K04146

Entry

K04146                      KO

Symbol

DRD3

Name

dopamine receptor D3

Pathway

map04080

Neuroactive ligand-receptor interaction

map04728

Dopaminergic synapse

Disease

H01577

Essential tremor

H01649

Schizophrenia

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04146  DRD3; dopamine receptor D3
09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    K04146  DRD3; dopamine receptor D3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04146  DRD3; dopamine receptor D3
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Biogenic amine
   Dopamine
    K04146  DRD3; dopamine receptor D3

Other DBs

GO:

0001591

TC:	9.A.14.3.9

Genes

HSA:	1814(DRD3)

PTR:	470885(DRD3)

PPS:	100984609(DRD3)

GGO:	101132878(DRD3)

PON:	100454395(DRD3)

NLE:	100594342(DRD3)

HMH:	116466316(DRD3)

MCC:	100425047(DRD3)

MCF:	102123487(DRD3)

MTHB:

126949262

MNI:	105470374(DRD3)

CSAB:

103228289(DRD3)

CATY:

105596287(DRD3)

PANU:

101009027(DRD3)

TGE:	112618986(DRD3)

MLEU:

105529632(DRD3)

RRO:	104660606(DRD3)

RBB:	108519483(DRD3)

TFN:	117076621(DRD3)

PTEH:

111541871(DRD3)

CANG:

105510704(DRD3)

CJC:	100398788(DRD3)

SBQ:	101037836(DRD3)

CIMI:

108317405

CSYR:

103268304(DRD3)

MMUR:

105883933(DRD3)

LCAT:

123642077(DRD3)

PCOQ:

105816746(DRD3)

OGA:	100959253(DRD3)

MMU:	13490(Drd3)

MCAL:

110311792(Drd3)

MPAH:

110329875(Drd3)

RNO:	29238(Drd3)

MCOC:

116086417(Drd3)

ANU:	117718078(Drd3)

MUN:	110557780(Drd3)

CGE:	100769070(Drd3)

MAUA:

101836535(Drd3)

PROB:

127227182(Drd3)

PLEU:

114694979(Drd3)

MORG:

121461963(Drd3)

MFOT:

126505783

AAMP:

119825223(Drd3)

NGI:	103741932(Drd3)

HGL:	101713857(Drd3)

CPOC:

100716075(Drd3)

CCAN:

109678247(Drd3)

DORD:

105994896(Drd3)

DSP:	122105576(Drd3)

PLOP:

125351292(Drd3)

NCAR:

124993306

MMMA:

107136186(Drd3)

OCU:

100343485

OPI:	101517452(DRD3)

TUP:	102483861(DRD3)

GVR:	103596516(DRD3)

CFA:	487984(DRD3)

CLUD:

112678084(DRD3)

VVP:	112913445(DRD3)

VLG:	121501338(DRD3)

NPO:	129503916(DRD3)

AML:	100474054(DRD3)

UMR:	103678807(DRD3)

UAH:	113256431(DRD3)

UAR:	123784294(DRD3)

ELK:

111150975

LLV:

125078618

MPUF:

101690016(DRD3)

MNP:	132010189(DRD3)

MLK:	131825114(DRD3)

NVS:	122910426(DRD3)

ORO:	101368111(DRD3)

EJU:	114214824(DRD3)

ZCA:	113917541(DRD3)

MLX:	118000626(DRD3)

NSU:	110582507(DRD3)

LWW:	102738050(DRD3)

FCA:	101092878(DRD3)

PYU:	121036262(DRD3)

PCOO:

112849609(DRD3)

PBG:	122491463(DRD3)

PVIV:

125174774(DRD3)

LRUF:

124526951

PTG:	102956080(DRD3)

PPAD:

109266419(DRD3)

PUC:

125921764

AJU:

106977772

HHV:	120226664(DRD3)

BTA:	537043(DRD3)

BOM:	102280251(DRD3)

BIU:	109564092(DRD3)

BBUB:

102413222(DRD3)

BBIS:

104992461(DRD3)

CHX:	102188084(DRD3)

OAS:	101103110(DRD3)

BTAX:

128054403(DRD3)

ODA:	120851621(DRD3)

CCAD:

122445563(DRD3)

MBEZ:

129550589(DRD3)

SSC:	100513049(DRD3)

CFR:	102519907(DRD3)

CBAI:

105081577(DRD3)

CDK:	105093194(DRD3)

VPC:	102543321(DRD3)

BACU:

103008846(DRD3)

BMUS:

118894684(DRD3)

LVE:	103075834(DRD3)

OOR:	101290463(DRD3)

DLE:	111175367(DRD3)

PCAD:

102976222(DRD3)

PSIU:

116753273(DRD3)

NASI:

112393245(DRD3)

ECB:	100061160(DRD3)

EPZ:	103552929(DRD3)

EAI:	106829519(DRD3)

MYB:	102259828(DRD3)

MYD:	102756066(DRD3)

MMYO:

118676717(DRD3)

MLF:	102417311(DRD3)

PKL:	118724413(DRD3)

EFUS:

103290699(DRD3)

MNA:	107527386(DRD3)

DRO:	112320584(DRD3)

SHON:

118994705(DRD3)

AJM:	119043035(DRD3)

PDIC:

114490900(DRD3)

PHAS:

123827280(DRD3)

MMF:	118617453(DRD3)

PPAM:

129073658(DRD3)

HAI:	109387959(DRD3)

RFQ:	117037768(DRD3)

PALE:

102878121(DRD3)

PGIG:

120586623(DRD3)

PVP:	105303360(DRD3)

RAY:	107513697(DRD3)

MJV:	108392279(DRD3)

TOD:	119256822(DRD3)

SARA:

101540729(DRD3)

SETR:

126026070(DRD3)

LAV:	100676993(DRD3)

TMU:

101353801

ETF:	101651277(DRD3)

DNM:	101429338(DRD3)

MDO:	100014112(DRD3)

GAS:	123239489(DRD3)

SHR:	100913402(DRD3)

AFZ:

127554085

PCW:	110222242(DRD3)

GGA:	770757(DRD3)

PCOC:

116242389(DRD3)

MGP:	100549401(DRD3)

CJO:	107320208(DRD3)

TPAI:

128091532(DRD3)

LMUT:

125687975(DRD3)

NMEL:

110399597(DRD3)

APLA:

101799559(DRD3)

ACYG:

106037929(DRD3)

CATA:

118245002(DRD3)

AFUL:

116496915(DRD3)

TGU:	100190794(DRD3)

LSR:	110480696(DRD3)

SCAN:

103827090(DRD3)

PMOA:

120506415(DRD3)

OTC:	121339260(DRD3)

PRUF:

121351608(DRD3)

GFR:	102032767(DRD3)

FAB:	101806210(DRD3)

OMA:	130252511(DRD3)

PHI:	102110328(DRD3)

PMAJ:

107203499(DRD3)

CCAE:

111939296(DRD3)

CCW:	104687064(DRD3)

CBRC:

103614024(DRD3)

ETL:	114055119(DRD3)

ZAB:	102073117(DRD3)

ACHL:

103799605(DRD3)

SVG:	106854569(DRD3)

MMEA:

130572495(DRD3)

HRT:	120749547(DRD3)

FPG:	101922369(DRD3)

FCH:	102052693(DRD3)

CLV:	102095168(DRD3)

EGZ:	104126235(DRD3)

NNI:	104014076(DRD3)

PCRI:

104025009(DRD3)

PLET:

104616237(DRD3)

EHS:	104517208(DRD3)

PCAO:

104047537

ACUN:

113485051(DRD3)

TALA:

104368708(DRD3)

PADL:

103921515(DRD3)

AFOR:

103907478(DRD3)

ACHC:

115343711(DRD3)

HALD:

104311002(DRD3)

HLE:	104831685(DRD3)

AGEN:

126049109

GCL:

127015651

CCRI:

104169578(DRD3)

CSTI:

104553292(DRD3)

CMAC:

104476590

MUI:	104537666(DRD3)

BREG:

104634337(DRD3)

FGA:	104073739(DRD3)

GSTE:

104254693(DRD3)

LDI:	104344111(DRD3)

MNB:	103775934(DRD3)

OHA:	104333898(DRD3)

NNT:	104401305(DRD3)

SHAB:

115601555(DRD3)

DPUB:

104307061(DRD3)

PGUU:

104470573(DRD3)

ACAR:

104518562(DRD3)

CPEA:

104389267(DRD3)

AVIT:

104275531(DRD3)

CVF:	104281862(DRD3)

RTD:	128914726(DRD3)

CUCA:

104055797(DRD3)

TEO:	104370418(DRD3)

BRHI:

104496577(DRD3)

AAM:	106490539(DRD3)

AROW:

112974038(DRD3)

NPD:	112945579(DRD3)

TGT:	104571920(DRD3)

DNE:	112979639(DRD3)

SCAM:

104144268(DRD3)

ASN:	102386496(DRD3)

AMJ:	102576256(DRD3)

CPOO:

109319311(DRD3)

GGN:	109304870(DRD3)

PSS:	102451549(DRD3)

CMY:	102938985(DRD3)

CCAY:

125621289(DRD3)

DCC:	119861431(DRD3)

CPIC:

101942822(DRD3)

TST:	117871033(DRD3)

CABI:

116822763(DRD3)

MRV:	120373112(DRD3)

ACS:	100556183(drd3)

ASAO:

132772070(DRD3)

PVT:	110084757(DRD3)

SUND:

121926367(DRD3)

PBI:	103054341(DRD3)

PMUR:

107288264(DRD3)

VKO:	123029343(DRD3)

PMUA:

114595824(DRD3)

PRAF:

128412765(DRD3)

ZVI:	118078335 118084770(DRD3)

HCG:	128348861(DRD3)

GJA:	107112443(DRD3)

STOW:

125430434(DRD3)

EMC:	129326051(DRD3)

MUO:	115471328(DRD3)

GSH:	117359702(DRD3)

DRE:	282554(drd3)

SRX:	107733056 107754942

SANH:

107654199 107701643

SGH:	107585015 107591280

CCAR:

109058564 109085564

CAUA:

113042725 113065960

CGIB:

127945900 128012933

PTET:

122330234(drd3)

LROH:

127155373(drd3)

OMC:	131533217(drd3)

PPRM:

120476053(drd3)

RKG:	130083855(drd3)

MAMB:

125258403(drd3)

CIDE:

127506501

MASI:

127432042 127434797

TROS:

130547402(drd3)

TDW:	130413329(drd3)

MANU:

129426282(drd3)

IPU:

108256204

IFU:	128599968(drd3)

PHYP:

113541240(drd3)

SMEO:

124375668(drd3)

TFD:	113661610(drd3)

TVC:	132840188(drd3)

AMEX:

103024755(drd3)

CMAO:

118798772(drd3) 118814062

EEE:

113581235

CHAR:

105890089(drd3)

TRU:	101061574(drd3)

TFS:	130513955(drd3)

TNG:	GSTEN00023894G001

LCO:	104934476(drd3)

TBEN:

117493955 117498753(drd3)

CGOB:

115025762 115025802

PGEO:

117449333 117465506(drd3)

GACU:

117535851(drd3)

EMAC:

134883769(drd3)

ELY:	117264462(drd3)

EFO:	125882182(drd3)

PLEP:

121960747(drd3)

SLUC:

116037971(drd3)

ECRA:

117937613(drd3)

ESP:	116672402(drd3)

PFLV:

114549091(drd3)

GAT:	120811924(drd3)

PPUG:

119198815(drd3)

AFB:	129110842(drd3)

CLUM:

117749578(drd3)

PSWI:

130206158(drd3)

MSAM:

119910027(drd3)

SCHU:

122866291(drd3)

CUD:	121527436(drd3)

ALAT:

119008825(drd3)

MZE:	101466511(drd3)

ONL:	100700994(drd3)

OAU:	116314531(drd3)

OLA:	101163209(drd3)

OML:	112151030(drd3)

CSAI:

133422967(drd3)

XHE:	116712258(drd3)

PFOR:

103139760(drd3)

PLAI:

106944641(drd3)

PMEI:

106909294(drd3)

GAF:	122824330(drd3)

PPRL:

129364818(drd3)

CTUL:

119778832

GMU:	124858480(drd3)

NFU:	107382847(drd3)

KMR:	108230287(drd3)

ALIM:

106513406(drd3)

NWH:	119426580(drd3)

AOCE:

111565955 111572874

MCEP:

125024391(drd3)

CSEM:

103377231(drd3)

POV:	109629576(drd3)

SSEN:

122775385(drd3)

HHIP:

117753862(drd3)

HSP:	118098946(drd3)

SMAU:

118290884(drd3)

LCF:

108881734

SDU:	111220952(drd3)

SLAL:

111662989(drd3)

XGL:	120790149(drd3)

HCQ:	109514061(drd3)

SSCV:

125985745

SBIA:

133492796(drd3) 133494432

PEE:	133396585(drd3)

PTAO:

133470413(drd3) 133490028

BPEC:

110160994(drd3)

MALB:

109960079(drd3)

BSPL:

114853454(drd3) 114853455 114853483

SJO:	128382310(drd3)

SASA:

106579486 106590468

STRU:

115151465 115195266

OTW:	112216544 112252992

OMY:	110490825 110535364(drd3)

OGO:	123990248(drd3) 124039126

ONE:	115104498 115131083

OKI:	109900139 109909731

OKE:	118373642(drd3) 118382487

SALP:

111973273

SNH:	120028047(drd3) 120050963

CCLU:

121549504(drd3) 121569272

ELS:	105021975(drd3)

PKI:	111860966(drd3)

LOC:	102695188(drd3)

PSPA:

121302597(drd3)

ARUT:

117406286 117972721

PSEX:

120523110(drd3)

LCM:

102359087

CMK:	103183539(drd3)

CPLA:

122555031(drd3)

HOC:	132820718(drd3)

LERI:

129702615(drd3)

PCLA:

ESN:

LPOL:

BGT:

GAE:

MMER:

123540381 123554373 123555479

RPHI:

132720326 132723551

ATEN:

116300804 116304932

SPIS:

111330923

XEN:	124435718 124454146

» show all

Reference

PMID:19520868

Authors

Villar VA, Jones JE, Armando I, Palmes-Saloma C, Yu P, Pascua AM, Keever L, Arnaldo FB, Wang Z, Luo Y, Felder RA, Jose PA

Title

G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor.

Journal

J Biol Chem 284:21425-34 (2009)
DOI:10.1074/jbc.M109.003665

Sequence

[hsa:1814]

Reference

PMID:8415635

Authors

Schmauss C, Haroutunian V, Davis KL, Davidson M

Title

Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia.

Journal

Proc Natl Acad Sci U S A 90:8942-6 (1993)
DOI:10.1073/pnas.90.19.8942

Sequence

[hsa:1814]

All links

Ontology (4)   
   KEGG BRITE (2)   
   GO (1)   
   TC (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (2)   
   KEGG DISEASE (2)   
Drug (33)   
   KEGG DRUG (33)   
Gene (621)   
   KEGG GENES (409)   
   KEGG MGENES (117)   
   RefGene (93)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (666)   

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